Research titles (with abstracts) from the Islands.  The research articles are accessed from the ISI web of knowledge website.

This post lists 350 papers, all published with at least one Philippine address. From nasal spray to bioactive sesquiterpene, from starfish to new frogs, from fuzzy modelling to semiconductor photoluminescence, the topics are as diverse as the sizes of the islands.

I will try to make a summary of a research that you find interesting but no promises.  Email me for request.


Publication type J
Title Stock trading system based on the multi-objective particle swarm optimization of technical indicators on end-of-day market data
Author/s Briza, AC Naval, PC
Vol 11
Issue 1
Start page 1191
End page 1201
Publication year 2011
Times cited 0
Abstract Stock traders consider several factors or objectives in making decisions. Moreover, they differ in the importance they attach to each of these objectives. This requires a tool that can provide an optimal tradeoff among different objectives, a problem aptly solved by a multi-objective optimization (MOO) system. This paper aims to investigate the application of multi-objective optimization to end-of-day historical stock trading. We present a stock trading system that uses multi-objective particle swarm optimization (MOPSO) of financial technical indicators. Using end-of-day market data, the system optimizes the weights of several technical indicators over two objective functions, namely, percent profit and Sharpe ratio. The performance of the system was compared to the performance of the technical indicators, the performance of the market, and the performance of another stock trading system which was optimized with the NSGA-II algorithm, a genetic algorithm-based MOO method. The results show that the system performed well on both training and out-of-sample data. In terms of percent profit, the system outperformed most, if not all, of the indicators under study, and, in some instances, it even outperformed the market itself. In terms of Sharpe ratio, the system consistently performed significantly better than all the technical indicators. The proposed MOPSO system also performed far better than the system optimized by NSGA-II. The proposed system provided a diversity of solutions for the two objective functions and is found to be robust and fast. These results show the potential of the system as a tool for making stock trading decisions. (C) 2010 Elsevier B.V. All rights reserved.
UT WOS:000281591300118
SN 1568-4946
doi 10.1016/j.asoc.2010.02.017

Publication type J
Title Effect of high temperature and water stress on pollen germination and
spikelet fertility in rice
Author/s Rang, ZW Jagadish, SVK Zhou, QM Craufurd, PQ Heuer, S
Vol 70
Issue 1
Start page 58
End page 65
Publication year 2011
Times cited 1
Abstract In future climates, rice could more frequently be subjected to
simultaneous high temperature and water stress during sensitive
developmental stages such as flowering. In this study, five rice
genotypes were exposed to high temperature, water stress and combined
high temperature and water stress during flowering to quantify their
response through spikelet fertility. Microscopic analyses revealed
significant differences in anther dehiscence between treatments and
genotypes, with a moderately high association with the number of
germinated pollen grains on the stigma. There was a strong relationship
between spikelet fertility and the number of germinated pollen on
stigmas. Although, all three stress treatments resulted in spikelet
sterility, high-temperature stress caused the highest sterility in all
five genotypes. A cumulative linear decline in spikelet fertility with
increasing duration of independent high-temperature stress and in
combination with water stress was quantified. Better anther dehiscence,
higher in vivo pollen germination, and higher spikelet fertility were
observed in both the N22 accessions compared with IR64, Apo and
Moroberekan under high temperature, water stress and combined stress,
indicating its ability to tolerate multiple abiotic stresses. (C) 2010
Elsevier B.V. All rights reserved.
UT WOS:000283485100008
SN 0098-8472
doi 10.1016/j.envexpbot.2010.08.009

Publication type J
Title Screening for potential anti-angiogenic property utilizing avian embryo
chorioallantois membranes (CAMs) II. Garlic (Allium sativum L.) oil
Author/s Ramos, GB Arguelles, CL Herrera, AA Ragasa, CV
Vol 20
Issue 1
Start page 13
End page 23
Publication year 2011
Times cited 0
Abstract To examine the anti-angiogenic property of garlic (Allium sativum L.)
oil, the blood vessel formation and branching complexity in the
chorioallantoic membranes (CAMs) of avian embryos were measured
quantitatively by histologic microvessel point counting and macroscopic
fractal dimension analysis. Surgical gelfoams, as matrix for the
growing blood vessels, were implanted onto the CAMs. Seventy three-day
old fertilized whiteleghorn eggs were divided into negative control
(NC), which received neither phosphate buffered saline (PBS) norgarlic
oil, three positive control (PC) which received 20, 50 and 100 mu l PBS
and three treatment groups (TG) which received 20, 50 and 100 mu l
garlic oil. The study lasted for 13 days during which samples were kept
in constant 37 degrees C. On the last day, the gelfoam implants with
the surrounding CAMs were detached from the embryos and processed for
light microscopy. A second batch of duck fertilized eggs was run in
similar conditions. The CAMs were removed on the last day, mounted on
water-absorbent white boards and photographed with macrolens for the
fractal dimension analysis. Results showed that garlic oil
significantly reduced the number of microvessels per area in the chick
embryo CAMs in a dose-dependent manner, that is, the higher the dose,
the lower the percent microvessel area incurred. A decreasing trend in
blood vessel branching complexity was found in the fractal dimension
analysis but not significantly different from the other groups. While
there is a discrepancy in the results of the two assays, the potential
anti-angiogenic property of garlic oil could not be disregarded.
Possibly, an increase in the sample size could increase the power of
the statistical test and may yield more conclusive results.
UT WOS:000283469900002
SN 0117-3375

Publication type J
Title Patch richness and shape complexity in Central Cebu Protected
Landscape, Cebu Island, Philippines: Implications in Environmental
Author/s Bagarinao, RT
Vol 20
Issue 1
Start page 25
End page 35
Publication year 2011
Times cited 0
Abstract The many advances in the field of landscape ecology allow the analysis
of landscape structure vis-a-vis ecological processes. The study was
conducted to measure patch richness (PR) and shape complexity (i.e.
perimeter-to-area ratio, PAR) of the various patch classes in Central
Cebu Protected Landscape (CCPL). CCPL is an important biodiversity zone
in the Central Visayas region due to its high endemicity. Both patch
richness and shape complexity indices were measured, and their
implications on the management of the landscape were identified. CCPL
consists of four patch classes, namely: perennial crops, annual crops,
forests and built-up areas. Though annual crops showed the highest size
in all patch types, the perennial crops have the highest patch number.
PAR and PR values of forest patches indicate forest ecosystems in the
landscape are highly fragmented and have greater edge than core area.
If conservation objective is to protect endangered species from
extinction, landscape management should focus on the establishment of
connections among isolated forest patches. In particular, management
should consider establishing patches with maximum core area if
conservation is for the protection of core-dependent species.
UT WOS:000283469900003
SN 0117-3375

Publication type J
Title New species and records of Oribatida and other soil-inhabiting mites
(Acari) mainly from Luzon and Mindanao islands, Philippines
Author/s Corpuz-Raros, LA Gruezo, WS
Vol 20
Issue 1
Start page 37
End page 61
Publication year 2011
Times cited 0
Abstract Five new species of oribatid mites are described as new to science:
Phyllhermannia pinicola Corpuz-Raros & Gruezo (Hermanniidae),
Ceratoppia filipina Corpuz-Raros & Garcia (Peloppiidae), Basiceremaeus
igorotus Corpuz-Raros & Gruezo (Otocepheidae) and Nesopelops
philippinensis Corpuz-Raros & Garcia (Phenopelopidae), all from La
Trinidad, Benguet, Luzon Is. and Dolicheremaeus pahabaeus Corpuz-Raros
& Gruezo (Otocepheidae) from Mindanao Is. Five species are also
recorded for the first time in the Philippines: the cunaxid
(Actinedida) Dactyloscirus machairodus (Oudemans) and the oribatids,
Heminothrus minor Aoki (Camisiidae)., Nippohermannia parallela (Aoki)
(Nanhermanniidae), Acrotocepheus bajau (Mahunka) (Otocepheidae) and
Nasozetes choreognathus Willmann (Hemileidae).
UT WOS:000283469900004
SN 0117-3375

Publication type J
Title Effects of undigested fraction of soybean protein on lipid metabolism
in Brown Norway rats with different age groups
Author/s Gatchalian-Yee, MV
Vol 20
Issue 1
Start page 77
End page 85
Publication year 2011
Times cited 0
Abstract Soybean protein was reported to lower cholesterol. However, these
proteins tend to have bitter taste. Debittering or removing the taste
of soybean may be done to improve the taste of soybean.
This study was conducted to investigate the effect of feeding
debittered undigested fraction of soybean in young and adult Brown
Norway rats. Eighteen 4- and 32-week old male Brown Norway rats were
fed for 22 days with 3 types of protein sources: casein (CAS), soybean
(SOY) and debittered undigested fraction of soybean (UDF). The rats
were divided into 3 groups with 6 rats per group. Debittered UDF from
soybean isolate did not exert any aggravating effect on the age-related
change in lipid metabolism. Both serum and liver cholesterol levels
were decreased when UDF was fed in both age groups. Adult rats showed
to have a comparable desaturation index while debittered UDF-fed young
rats demonstrated the lowest desaturation index. Debittered UDF might
not be efficient in increasing the desaturation of linoleic acid to
arachidonic acid.
UT WOS:000283469900006
SN 0117-3375

Publication type J
Title An embryoprotective role of Parameria laevigata (A. Juss.) Moldenke in
vitamin A teratogenesis in Mus musculus L.
Author/s Cajuday, LA Herrera, AA
Vol 20
Issue 1
Start page 87
End page 98
Publication year 2011
Times cited 0
Abstract Evaluation for possible embryoprotective/antiteratogenic role using the
hexane fraction obtained from the leaves of Parameria laevigata (A.
Juss.) Moldenke was performed on pregnant ICR mice (Mus musculus L.).
The overall effect of the treatment with P laevigata hexane fraction on
maternal reproductive performance was manifested by the significant
differences observed (p <= 0.05) on the number of live and dead fetuses
per litter between the groups. The incidence of live fetuses was high
and the frequency of dead fetuses per litter was low in all the groups
that received the plant extract including the group that was exposed to
Vitamin A while more dead fetuses/litter (2 +/- 0.71)and less live
fetuses/litter (8.8 +/- 1.1) were seen from the group exposed to
vitamin A only. Morphological analysis of the live fetuses revealed
normal appearance in all the groups except samples exposed to the
teratogen. There was a significant difference in terms of mean fetal
weight and morphological abnormalities per litter between the groups.
The lowest mean fetal weight per litter was obtained from the group
administered with plain vitamin A (0.55 +/- 0.14) and the highest value
was recorded from mice exposed to 50 mg of P laevigata plain (0.92 +/-
0.2) or adjunct to vitamin A (1.02 +/- 0.12). Bone maturation was
greatly reduced by vitamin A administration. Regions significantly
affected include the long bones in the forelimbs and hind limbs. The
degree of ossification was enhanced by treatment with P laevigata
hexane fraction and the effect of the teratogen in reducing bone
mineralization was counteracted in the treated samples given with the
medium and high doses of the plant extract.
UT WOS:000283469900007
SN 0117-3375

Publication type J
Title Taxonomy of flagellated algae in brackish- and freshwater fishponds in
Central Luzon, Philippines
Author/s Boonmee, S Martinez-Goss, MR Shin, W
Vol 20
Issue 1
Start page 99
End page 141
Publication year 2011
Times cited 0
Abstract Monthly water samplings for algae for one year were conducted from
brackish (BW) and freshwater (FW) fishponds in Bulacan, Bulacan and
Munoz, Nueva Ecija, in Central Luzon, Philippines, respectively. A
total of 58 species of flagellated algae (in their vegetative state)
were identified belonging to five divisions, six classes and 18 genera.
Thirty two new records and one new variety, Trachelomonas volvocina
Ehrenberg var. collaris Boonmee, var nov. (Euglenophyta) are described
in this paper. All the 42 species of euglenophytes were observed in the
freshwater fishponds only while of the 10 species of chlorophytes,
three species were found in BW ponds, five in FW ponds and two species
in both types of pond. Diagnostic descriptions, illustrations,
photographs and habitat records are given for each species or variety.
A key is presented for the species in each division or genus.
UT WOS:000283469900008
SN 0117-3375

Publication type J
Title Feeding habits of Visayan leopard cats (Prionailurus bengalensis
rabori) in sugarcane fields of Negros Occidental, Philippines
Author/s Fernandez, DAP de Guia, APO
Vol 20
Issue 1
Start page 143
End page 154
Publication year 2011
Times cited 0
Abstract The Visayan leopard cat (Prionailurus bengalensis rabori) is a small
wild felid of the Negros-Panay faunal region of the Philippines. In
Negros Occidental, many individuals wander into sugarcane fields and
game fowl farms due to the declining forests, causing locals to believe
that leopard cats eat sugarcane or prey on chicks. This study was
conducted to determine the actual feeding habits of Visayan leopard
cats through scat analysis. The cuticular and medullary patterns of
hair from 25 scats collected from May to October 2009 were analyzed to
identify prey species. Results suggest that there are no defined areas
where leopard cat scats and scats from other animals are found. The
first scats were collected in July, increasing until October while none
was collected in May and June. Results suggest that the presence of
Visayan leopard cats in sugarcane fields is influenced by the growth of
sugarcane which attracts rodents. The main prey species consumed by
Visayan leopard cats were Mus musculus (96%), Rattus exulans (96%),
Rattus argentiventer (64%) and Rattus tanezumi (32%) concurring with
many studies that small mammals are the main prey items of leopard
cats. Also, results showed that Visayan leopard cats do not eat birds
or plant matter exclusively, contrary to local belief.
UT WOS:000283469900009
SN 0117-3375

Publication type J
Title Human-forest interaction in Aborlan Guba System, Palawan Island,
Philippines: Implications for Conservation and Management
Author/s Sopsop, LB Buot, IE
Vol 20
Issue 1
Start page 155
End page 173
Publication year 2011
Times cited 0
Abstract The dynamics of human-forest interaction in Aborlan Guba System,
Aborlan, Palawan was determined by doing social and literature surveys
and by using the STELLA program for model development. The direct users
of the forest were poor Indigenous Peoples and migrants. Income, family
size, education and size of cultivated farm significantly influenced
the harvest frequency of forest products.
Using current data and trends to extrapolate conditions over the next
50 years, the simulation showed that the Aborlan Guba System would
become less and less sustainable in ecological and socioeconomic terms.
The model projected that forest cover declines at 3 ha/year.
The best way to sustainably manage the Aborlan Guba System is by
increasing people’s income, reducing population growth and increasing
reforestation efforts especially for rattan species and almaciga trees.
For immediate protection, the area must be upgraded from a Controlled
Use Zone to Core Zone but declaring it into a Protected Area under
NIPAS law ensures its long term sustainability.
UT WOS:000283469900010
SN 0117-3375

Publication type J
Title Assessment of the fitness status of an individual using
kinanthropometric tests
Author/s Buot, MM
Vol 20
Issue 1
Start page 175
End page 184
Publication year 2011
Times cited 0
Abstract There is always the need to regularly monitor fitness status not only
of athletes but of non-athletes as well. This paper is to address this
necessity in order to minimize occurrences of common cardio-respiratory
ailments plaguing through these years, hence enhancing and sustaining a
healthy population.
A total of 510 male and female respondents were included in the 3-year
study of assessing the health status of physical education students at
the University of the Philippines Los Banos, College, Laguna. Analyzing
relationship of anthropometric measures (body mass index and waist-hip
ratio) with some performance indices/musculoskeletal fitness (such as
curl up, push up and sit and reach) through regular physical fitness
test were also done.
Generally, students believe and accept the fact that there are
countless benefits derived from doing a regular exercise and living a
healthy lifestyle. The main problem though is the availability of the
program that would suit to their lifestyle and busy schedules. It is
always the duty of the university, the college and the department to
organize programs that could address individual needs.
UT WOS:000283469900011
SN 0117-3375

Publication type J
Title Diversity and spatial distribution patterns of macro land snails in
Mount Makiling Forest Reserve, Philippines
Author/s de Chavez, ERC de Lara, AV
Vol 20
Issue 1
Start page 185
End page 201
Publication year 2011
Times cited 1
Abstract The diversity, relative abundance and spatial distribution of macro
land snails (>5mm) were determined in the Mount Makiling Forest
Reserve, Luzon Island, Philippines. Four slopes
(northeast-UPLB-Forestry, southeast-MakBan, northwest-Puting Lupa and
southwest-Sipit) were selected and divided into three elevation
gradients: upper (>600 mast), middle (500-600 masl) and lower (<500
mast) wherein 36 20 x 20 m(2) quadrats were randomly set. Altitude,
temperature, top soil pH, exchangeable calcium, forest type, canopy
cover, number and diameter of trees, and leaf litter depth were
determined or measured. A total of 639 individuals belonging to five
families (Achatinidae, Bradybaenidae, Camaenidae, Cyclophoridae and
Helicarionidae) and 14 species were identified. Of the four slopes,
Puting Lupa had the most number of individuals (299) and species (11)
while MakBan had the least (48 and 3). The most common species was
Ryssota otaheitana (41.47%) while Cochloslyla camelopardalis was the
rarest (0.16%). Canonical correspondence analysis (CCA) showed
significant direct correlation between species and the primary and
mid-montane forests, except for Achatina fulica which was more
associated with mahogany plantations and former slash and burn sites.
The dominant limiting variables for land snail composition were
altitude, temperature, canopy cover and exchangeable calcium. The
present research suggests that endemic macro land snails are more
abundant and diverse in intact and undisturbed forests, and the strong
association of helicostylids to native forest could qualify the group
as potential indicators of healthy forest ecosystems.
UT WOS:000283469900012
SN 0117-3375

Publication type J
Title Nutritional value, physico-chemical properties and acceptability of
rice (Oryza sativa L.)-corn (Zea mays L.) composites
Author/s Nagares, ND Hurtada, WA Rodriguez, FM Dizon, EI
Vol 20
Issue 1
Start page 203
End page 218
Publication year 2011
Times cited 0
Abstract IR 72 rice variety (high-amylose type) was combined with IPB Var. 6, a
Quality Protein Maize (QPM) white corn, obtaining a total of nine
different rice-corn composites (rice and corn combination). QPM
contains nearly twice as much usable protein that is specifically rich
in lysine and tryptophan, the two limiting essential amino acids in
rice. Addition of QPM white corn grits to IR 72 rice variety increased
the amount of protein, lysine, tryptophan, fat, ash, starch, amylose
and total fiber content of the rice-corn composites. Gel consistency
and hardness were relatively higher in samples having more corn. Both
IR 72 rice variety and QPM white corn have the same gelatinization
temperature below 70 C. Generally, based on a 7-point Hedonic rating
scale for evaluation, all the rice-corn composites were considered
acceptable in terms of color, odor, flavor, cohesiveness and texture.
There was a significant difference in each sensory attribute except
cohesiveness. The sensory evaluation showed that the 70:30 (rice:corn)
ratio had the highest preference score in terms of flavor and general
acceptability. The study showed that combining IR 72 rice variety and
QPM white corn grits at a 70:30 ratio can be utilized as a staple food
owing to its improved nutritional and sensory qualities and thus, can
be used to ameliorate food insecurity in the Filipino families and
UT WOS:000283469900013
SN 0117-3375

Publication type J
Title Effect of simulated acid rain on the germination and early seedling
growth of Betis [Madhuca betis (Blanco) MacBride], Antipolo [Artocarpus
blancoi (Elmer) Merr.] and Kalantas (Toona calantas Merr. & Rolfe) in
two soil types in Laguna, Philippines
Author/s Carandang, VQ Tolentino, EL Cruz, RVO Castillo, AS Visco, RG Carandang, WM
Vol 20
Issue 1
Start page 243
End page 262
Publication year 2011
Times cited 0
Abstract The sensitivities of Betis [Madhuca betis (Blanco) Mac Bride], Antipolo
[Artocarpus. blancoi (Elmer) Merr.] and Kalantas (Toona calantas Merr.
& Rolfe) whose seeds were sown and maintained in two soil types,
namely: Makiling and Pansol soils were established by examining their
responses to four pH levels of simulated rain in terms of seed
germination and early growth of their seedlings. Germination value and
root length were not significantly affected by acidity treatment.
However, height and diameter growth, sturdiness quotient, shoot, root
biomass and shoot- root ratio were found significantly affected by
rainfall acidity. These parameters were then considered as most useful
indicators of sensitivity to acid treatment in the study area. Root
length was affected by acidity treatment and soil type and regarded as
less useful parameter in the study of the sensitivity of plants to acid
treatment. Of the three species studied, 7: calantas was observed to be
the most sensitive to changes in the acidity treatment levels. The
measurements obtained in all seedling growth parameters which were
round to be significantly different showed more remarkable changes in
the said species. With U. betis, the differences in the seedling
responses to the various pH levels of simulated acid rain were found to
be insignificant. Artocarpus blancoi was intermediate between T.
calantas and M. betis.
UT WOS:000283469900015
SN 0117-3375

Publication type J
Title Nonlinear maps from closed-loop tandems of A-to-D and D-to-A converters
Author/s Edang, AE Leynes, JKO Ella, RLA Labayane, RC Santiago, CM
Vol 16
Issue 3
Start page 1483
End page 1489
Publication year 2011
Times cited 0
Abstract A new class of dynamical maps arises from tandems consisting of an
analog-to-digital converter and a digital-to-analog converter when the
latter’s output is looped back to the formers input. Its nonlinear
function is created when at least one of the lines between the
converters is cut and that which connects to the DAC is tied to a
logical High. Other maps are produced when additional DAC input lines
are similarly altered, or instead clamped to a logical Low. The
resulting closed-loop systems exhibit several bifurcations including
that which lead to pseudo-randomness. Simulation results from numerical
analysis match fairly well with those derived from an electronic
circuit realization. (C) 2010 Elsevier B.V. All rights reserved.
UT WOS:000283826100035
SN 1007-5704
doi 10.1016/j.cnsns.2010.07.015

Publication type J
Title A multi-scale biophysical model to inform regional management of coral
reefs in the western Philippines and South China Sea
Author/s Melbourne-Thomas, J Johnson, CR Alino, PM Geronimo, RC Villanoy, CLGurney, GG
Vol 26
Issue 1
Start page 66
End page 82
Publication year 2011
Times cited 0
Abstract The health and functioning of coral reef ecosystems worldwide is in
decline, and in the face of increasing anthropogenic stress, the rate
of decline of these important ecosystems is set to accelerate.
Mitigation strategies at regional scales are costly, but nevertheless
critical, as reef systems are highly connected across regions by ocean
transport of both larval propagules and pollutants, It is essential
that these strategies are informed by sound science, but the inherent
complexity of coral reef systems confers significant challenges for
scientists and managers. Models are useful tools for dealing with
complexity and can inform decision making for coral reef management.
We develop a spatially explicit biophysical model for a general coral
reef system. The model couples dynamics from local (10(2) m) to
regional (10(6) m) scales, and explicitly incorporates larval
connectivity patterns derived from sophisticated larval dispersal
models. Here, we instantiate and validate the model for coral reefs in
the Philippines region of the South China Sea. We demonstrate how the
model can be used in decision support for coral reef management by
presenting two examples of regional-scale scenario projection relating
to key management issues in the Philippines: (i) marine reserve design
and the recovery of fish stocks; and (ii) synergistic effects between
coral bleaching and poor water quality. These scenarios highlight the
importance of considering multiple stressors to reef health and
patterns of larval connectivity in regional-scale management decisions.
(C) 2010 Elsevier Ltd. All rights reserved.
UT WOS:000283891600009
SN 1364-8152
doi 10.1016/j.envsoft.2010.03.033

Publication type J
Title Thermophysical property characterization of
Author/s Soriano, AN Cabahug, DIV Li, MH
Vol 43
Issue 2
Start page 186
End page 189
Publication year 2011
Times cited 0
Abstract In this present work, a thermophysical property characterization of
aqueous solution of tris(hydroxymethyl)aminomethane (TRIS), a
biological buffer, was done. The investigated properties were
refractive index (n), density (rho), and electrolytic conductivity
(kappa). These properties were measured for temperatures up to 353.15 K
(at normal atmospheric condition) and for the entire composition range
where TRIS is still soluble in water. The measured properties were
reported as functions of temperature and composition. A modified form
of the Vogel-Tamman-Fulcher equation which leads to an Arrhenius-type
asymptotic exponential function was used to generally correlate the
temperature and compositional dependence of the considered properties
and satisfactory results were obtained. (C) 2010 Elsevier Ltd. All
rights reserved.
UT WOS:000284570500011
SN 0021-9614
doi 10.1016/j.jct.2010.08.016

Publication type J
Title The phi(S) polar decomposition of matrices
Author/s De la Cruz, RJ Merino, DI Paras, AT
Vol 434
Issue 1
Start page 4
End page 13
Publication year 2011
Times cited 0
Abstract Let S is an element of M-2n be skew-symmetric and nonsingular. For X is
an element of M-2n, we show that the following are equivalent: (a) X
has a Os polar decomposition, (b) rank([X phi(S)(X)](i)) =
rank([phi(S)(X)X](i)) and rank([X phi(S)(X)X]X-i) is even for all
nonnegative integers i, and (c) X phi(S)(X) is similar to phi(S)(X)X
and rank([phi(S)(X)(i)]X]) is even for all nonnegative integer i. (C)
2010 Elsevier Inc. All rights reserved.
UT WOS:000284724500003
SN 0024-3795
doi 10.1016/j.laa.2010.09.001

Publication type J
Title Positioning strategic competitiveness of green business innovation
capabilities using hybrid method
Author/s Lin, YH Tseng, ML Chen, CC Chiu, ASF
Vol 38
Issue 3
Start page 1839
End page 1849
Publication year 2011
Times cited 0
Abstract There are intensive studies on the issues of environment practice and
business innovation capability, have been dealt with extensively from
practitioners and academicians, however, studies on the evaluation of
green business innovation capabilities (GBICs) are few. This study
tackles the evaluation assessment using fuzzy set theory, analytical
network process and importance-performance analysis. Specifically, this
study is using the theoretical framework of GBICs and proposed hybrid
approach, which are new in the theoretical and empirical literatures.
An expert group was empirical assessment to the perception on PWB
sector and a manufacturing firm is evaluated. The analytical results
indicated that this proposed hybrid method is a suitable and effective
method for identifying and analyzing the strategic competitiveness of
GBICs at case firm, especially when evaluation criteria are dependent
in uncertainty. (C) 2010 Elsevier Ltd. All rights reserved.
UT WOS:000284863200062
SN 0957-4174
doi 10.1016/j.eswa.2010.07.113

Publication type J
Title Ranking of predictor variables based on effect size criterion provides
an accurate means of automatically classifying opinion column articles
Author/s Legara, EF Monterola, C Abundo, C
Vol 390
Issue 1
Start page 110
End page 119
Publication year 2011
Times cited 0
Abstract We demonstrate an accurate procedure based on linear discriminant
analysis that allows automatic authorship classification of opinion
column articles. First, we extract the following stylometric features
of 157 column articles from four authors: statistics on high frequency
words, number of words per sentence, and number of sentences per
paragraph. Then, by systematically ranking these features based on an
effect size criterion, we show that we can achieve an average
classification accuracy of 93% for the test set. In comparison,
frequency size based ranking has an average accuracy of 80%. The
highest possible average classification accuracy of our data merely
relying on chance is similar to 31%. By carrying out sensitivity
analysis, we show that the effect size criterion is superior than
frequency ranking because there exist low frequency words that
significantly contribute to successful author discrimination.
Consistent results are seen when the procedure is applied in
classifying the undisputed Federalist papers of Alexander Hamilton and
James Madison. To the best of our knowledge, the work is the first
attempt in classifying opinion column articles, that by virtue of being
shorter in length (as compared to novels or short stories), are more
prone to over-fitting issues. The near perfect classification for the
longer papers supports this claim. Our results provide an important
insight on authorship attribution that has been overlooked in previous
studies: that ranking discriminant variables based on word frequency
counts is not necessarily an optimal procedure. (C) 2010 Elsevier B.V.
All rights reserved.
UT WOS:000284662500013
SN 0378-4371
doi 10.1016/j.physa.2010.03.016

Publication type J
Title Outcome of a hospital based multidisciplinary weight loss program in
obese Filipino children
Author/s Tan-Ting, AM Llido, L
Journal source NUTRITION
Vol 27
Issue 1
Start page 50
End page 54
Publication year 2011
Times cited 0
Abstract Background: Childhood obesity is becoming a problem for Filipino
children with an increasing national prevalence of pediatric overweight
and obesity. A multidisciplinary approach combining behavioral therapy
with diet and exercise is often advocated as having the greatest impact
in pediatric weight management.
Objective: To determine the effects of a weight loss program, which is
a staged 3-mo, multidisciplinary intervention consisting of combined
dietary, exercise, and behavioral methods in obese children.
Research methods and procedures: Prospective study done in a
hospital-based weight management center; duration of study: 15 mo
(November 2005 to January 2008); participants: 44 obese children (aged
5-17 y; body mass index [BMI] 85th-99th percentile); outcome measures:
change in weight, BMI, BMI z-score (SD score); secondary measures
included changes in waist circumference, blood pressure, and body fat.
Statistical tests: paired t tests, chi(2) test, Wilcoxon ranked sum
test, regression analysis, and ANOVA.
Results: At the end of the program, the patients demonstrated a
decrease in weight, BMI, BMI z-score, body fat, systolic blood
pressure, and waist circumference. Mean weight loss is 4.2 kg (P <
0.01) with an average of 5.3% weight loss; BMI decreased by 1.5 units
(P < 0.01), BMI z-score by 0.15 (P < 0.004), body fat by 14% (P <
0.01), systolic blood pressure by 7.25 mm Hg (P < 0.05), and waist
circumference by 5.4 cm (P < 0.05). Decrease in weight. BMI, and body
fat were significantly correlated with number of sessions attended.
Conclusion: The use of a multidisciplinary 3-mo staged program resulted
in an effective weight loss in obese Filipino children, which was
directly related to the frequency of sessions attended. (C) 2011
Elsevier Inc. All rights reserved.
UT WOS:000285659700008
SN 0899-9007
doi 10.1016/j.nut.2009.11.028

Publication type J
Title Deficiency in the amino aldehyde dehydrogenase encoded by GmAMADH2, the
homologue of rice Os2AP, enhances 2-acetyl-1-pyrroline biosynthesis in
soybeans (Glycine max L.)
Author/s Arikit, S Yoshihashi, T Wanchana, SUyen, TT Huong, NTT Wongpornchai, S Vanavichit, A
Vol 9
Issue 1
Start page 75
End page 87
Publication year 2011
Times cited 3
Abstract 2-Acetyl-1-pyrroline (2AP), the volatile compound that provides the
‘popcorn-like’ aroma in a large variety of cereal and food products, is
widely found in nature. Deficiency in amino aldehyde dehydrogenase
(AMADH) was previously shown to be the likely cause of 2AP biosynthesis
in rice (Oryza sativa L.). In this study, the validity of this
mechanism was investigated in soybeans (Glycine max L.). An assay of
AMADH activity in soybeans revealed that the aromatic soybean, which
contains 2AP, also lacked AMADH enzyme activity. Two genes, GmAMADH1
and GmAMADH2, which are homologous to the rice Os2AP gene that encodes
AMADH, were characterized. The transcription level of GmAMADH2 was
lower in aromatic varieties than in nonaromatic varieties, whereas the
expression of GmAMADH1 did not differ. A double nucleotide (TT)
deletion was found in exon 10 of GmAMADH2 in all aromatic varieties.
This variation caused a frame-shift mutation and a premature stop
codon. Suppression of GmAMADH2 by introduction of a GmAMADH2-RNAi
construct into the calli of the two nonaromatic wild-type varieties
inhibited the synthesis of AMADH and induced the biosynthesis of 2AP.
These results suggest that deficiency in the GmAMADH2 product, AMADH,
plays a similar role in soybean as in rice, which is to promote 2AP
biosynthesis. This phenomenon might be a conserved mechanism among
plant species.
UT WOS:000285012600008
SN 1467-7644
doi 10.1111/j.1467-7652.2010.00533.x

Publication type J
Title Content and Structure of Values in Middle Adolescence: Evidence From
Singapore, the Philippines, Indonesia, and Australia
Author/s Liem, GAD Martin, AJ Nair, E Bernardo, ABI Prasetya, PH
Vol 42
Issue 1
Start page 146
End page 154
Publication year 2011
Times cited 0
Abstract Schwartz’s theory of the content and structure of human values has been
validated mostly with adult (teacher and university student) samples.
The present study examines the content and structure of values of
middle adolescents in Singapore, the Philippines, Indonesia, and
Australia. The 40-item version of the Portrait Values Questionnaire was
administered to 230 adolescents in each country (total N = 920; boys
and girls were equal) and smallest space analysis was performed.
Consistent with theory, the 10 first-order values and the four
second-order values, organized in two bipolar dimensions, were
identified in all samples. In support of the developmentally modified
value model for young people, there was some evidence for the periphery
of power to achievement. Interestingly, the location of benevolence and
universalism were reversed across all cultural groups, and tradition
values separated into self-restriction and faith. Overall, the findings
support the claim that Schwartz’s theory of values is neither
restricted to adults nor solely based on a particular instrument and is
generalizable across diverse national contexts.
UT WOS:000284998400012
SN 0022-0221
doi 10.1177/0022022110383309

Publication type J
Title Rice spikelet rot disease in China – 2. Pathogenicity tests, assessment
of the importance of the disease, and preliminary evaluation of control
Author/s Huang, SW Wang, L Liu, LM Tang, SQ Zhu, DF Savary, S
Journal source CROP PROTECTION
Vol 30
Issue 1
Start page 10
End page 17
Publication year 2011
Times cited 2
Abstract In recent years a rice panicle disease-rice spikelet rot occurred
seriously in large rice-growing area in China, causing the rice grains
discolor, unfilled and deform It does not only influence the rice yield
because of the colored pathogens and toxigenic but also changes the
appearance of the rice and reduces its quality Spikelet rot disease
influences on the rice production and market price, and causes harm to
the safety and health of human and livestock This paper makes effort to
elucidate the occurrence epidemic regularity of the disease the
pathogenicity of isolates Fungicides to control the disease were
preliminarily selected in lab and control efficiency test were
conducted in field The investigation results indicate that japonica
varieties and their hybrid combination tighten panicle varieties are
easier to be infected by the disease than that of the indica rice
varieties with loosen panicles It was propitious to the disease
occurrence and epidemic when rice late booting to flowering period met
the overcast rainy (high humidity) and warm (25-33 degrees C) climate
Indoor selection results showed that ketotriazole shows very good
restraint effect on the pathogens Seed treating with fungicide spraying
ketotriazole carbendazim + thiram mixture or tricyclazole at later
booting and/or flowering stage can reached over 70% control efficiency
to the disease (C) 2010 Published by Elsevier Ltd
UT WOS:000285119800002
SN 0261-2194
doi 10.1016/j.cropro.2010.06.008

Publication type J
Title Rice spikelet rot disease in China – 1. Characterization of fungi
associated with the disease
Author/s Huang, SW Wang, L Liu, LM Tang, SQ Zhu, DF Savary, S
Journal source CROP PROTECTION
Vol 30
Issue 1
Start page 1
End page 9
Publication year 2011
Times cited 2
Abstract Rice spikelet rot disease (SRD) is an emerging disease of rice panicle
in China which affects both rice yield and grain quality Four fungal
pathogens were isolated from diseased rice grains Morphological
observation biological testing and molecular characterization led to
identify these fungi as Fusarium proliferatum Bipolaris australiensis
Curvularia lunata and Alternaria tenuis The four fungi can grow from 10
degrees C to 40 degrees C and from pH 5 to pH 10 The most suitable
temperature range is 25 degrees C-30 degrees C however the optimal pH
for sporulation of these fungi varies greatly The four fungi can grow
on media supplemented with different carbon and nitrogen sources These
differences in carbon and nitrogen requirements suggest differences in
trophism and have large effects on hyphal growth and spore production
The results suggest that rice SRD is caused by various fungi with
diverse physiological characteristics (C) 2010 Elsevier Ltd All rights
UT WOS:000285119800001
SN 0261-2194
doi 10.1016/j.cropro.2010.07.010

Publication type J
Title Extended release quetiapine fumarate (quetiapine XR) monotherapy as
maintenance treatment for generalized anxiety disorder: a long-term,
randomized, placebo-controlled trial
Author/s Katzman, MA Brawman-Mintzer, O Reyes, EB Olausson, B Liu, S Eriksson, H
Vol 26
Issue 1
Start page 11
End page 24
Publication year 2011
Times cited 0
Abstract The objective of this study was to evaluate the efficacy and
tolerability of extended release quetiapine fumarate (quetiapine XR) as
maintenance monotherapy for patients with generalized anxiety disorder
(GAD). Time-to-event (anxiety symptom recurrence; maximum 52 weeks)
multicenter, randomized-withdrawal, parallel-group, double-blind,
placebo-controlled study of quetiapine XR (50-300 mg/day) following
open-label run-in (4-8 weeks) and open-label stabilization (>= 12
weeks). Primary variable: time from randomization to anxiety event.
Secondary variables included: Hamilton Anxiety Rating Scale (HAM-A)
total, HAM-A psychic/somatic anxiety factors, Clinical Global
Impression-Severity of Illness (CGI-S), and Quality of Life, Enjoyment
and Satisfaction Questionnaire (Q-LES-Q) scores; adverse events (AE)
reporting. Four hundred and thirty-two patients, stabilized on
quetiapine XR, were randomized to continue quetiapine XR (N=216) or
switch to placebo (N=216). Risk of anxiety symptom recurrence was
significantly reduced by 81% for quetiapine XR versus placebo: hazard
ratio = 0.19 (95% confidence interval 0.12-0.31; P < 0.001). Fewer
patients receiving quetiapine XR (N=22, 10.2%) than placebo (N=84,
38.9%) experienced anxiety symptom recurrence. Significant differences
were observed between quetiapine XR and placebo in: HAM-A total,
psychic/somatic, CGI-S (all P < 0.001) and Q-LES-Q (P < 0.05) scores.
AEs (>10%) during open-label treatment were dry mouth, sedation,
somnolence, dizziness, fatigue, and constipation. During randomized
treatment, the most common AEs for quetiapine XR were headache and
nasopharyngitis. Quetiapine XR monotherapy reduced the risk of anxiety
symptom recurrence in patients with GAD stabilized on quetiapine XR,
with tolerability results consistent with the known profile of
quetiapine. Int Clin Psychopharmacol 26: 11-24 (C) 2010 Wolters Kluwer
Health vertical bar Lippincott Williams & Wilkins.
UT WOS:000285083700002
SN 0268-1315
doi 10.1097/YIC.0b013e32833e34d9

Publication type J
Title International reserves and swap lines: Substitutes or complements?
Author/s Aizenman, J Jinjarak, Y Park, D
Vol 20
Issue 1
Start page 5
End page 18
Publication year 2011
Times cited 0
Abstract Developing Asia experienced a sharp surge in foreign currency reserves
prior to the 2008-9 crisis. The global crisis has been associated with
an unprecedented rise of swap agreements between central banks of
larger economies and their counterparts in smaller economies. We
explore whether such swap lines can reduce the need for reserve
accumulation. The evidence suggests that there is only a limited scope
for swaps to substitute for reserves. The selectivity of the swap lines
indicates that only countries with significant trade and financial
linkages can expect access to such ad hoc arrangements, on a case by
case basis. Moral hazard concerns suggest that the applicability of
these arrangements will remain limited. However, deepening swap
agreements and regional reserve pooling arrangements may weaken the
precautionary motive for reserve accumulation. (C) 2010 Elsevier Inc.
All rights reserved.
UT WOS:000285122100002
SN 1059-0560
doi 10.1016/j.iref.2010.07.002

Publication type J
Title Enhanced wavefront reconstruction by random phase modulation with a
phase diffuser
Author/s Almoro, PF Pedrini, G Gundu, PN Osten, W Hanson, SG
Vol 49
Issue 2
Start page 252
End page 257
Publication year 2011
Times cited 0
Abstract A phase retrieval technique for enhanced wavefront reconstruction using
random phase modulation and a phase diffuser is proposed. The speckle
field generated is sampled at multiple axially displaced planes and the
speckle patterns are used in an iterative algorithm based on the
optical wave propagation in free space. The presentation of this
technique is carried out using two setups. In the first setup, a
diffuser plate is placed at the image plane of a metallic test object.
The benefit of randomizing the phase of the object wave is the enhanced
intensity recording due to high dynamic range of the diffusely
scattered beam. The use of demagnification optics will also allow the
investigations of relatively large objects. In the second setup, a
transparent object is illuminated using a wavefront with random phase
and constant amplitude by positioning the phase diffuser close to the
object. The benefit of phase-only modulation is the increased
resolution of the phase structures of the transparent test objects. (C)
2010 Elsevier Ltd. All rights reserved.
UT WOS:000285169500010
SN 0143-8166
doi 10.1016/j.optlaseng.2010.09.012

Publication type J
Title Fuzzy input-output model for optimizing eco-industrial supply chains
under water footprint constraints
Author/s Aviso, KB Tan, RR Culaba, AB Cruz, JB
Vol 19
Issue 2-3
Start page 187
End page 196
Publication year 2011
Times cited 0
Abstract Global water stress is expected to increase due to population growth,
economic development and climate change. Because of this trend, there
is an increased interest in the water intensity of industrial
activities conducted via the product supply chain or within specified
geographical boundaries or regions, both at the enterprise- or
regulatory-level. The total water footprint of economic activities
should be evaluated in consideration of local water resource
consumption, virtual water trade and resource availability. As
individual entities seek to protect their respective interests, the
challenge is to optimize inter-regional trade of goods with the
consideration of the interests of participants in the network. This
work presents a fuzzy input output model for optimizing supply chains
under water footprint constraints. Two case studies, involving tile
manufacturing and biofuel production, are considered to demonstrate the
use of the model. (C) 2010 Elsevier Ltd. All rights reserved.
UT WOS:000285227800010
SN 0959-6526
doi 10.1016/j.jclepro.2010.09.003

Publication type J
Title Heat-sensitizing effects of plant extracts on Clostridium spp. spores
Author/s Cui, HY Gabriel, AA Nakano, H
Journal source FOOD CONTROL
Vol 22
Issue 1
Start page 99
End page 104
Publication year 2011
Times cited 0
Abstract The effects of ethanol-soluble fractions of 12 plant extracts were
tested for heat-sensitizing effects on the spores of Clostridium
botulinum (type A and type B) and Clostridium sporogenes PA 3679.
Licorice, pineapple sage and lemon eucalyptus extracts were
respectively found to significantly decrease (P < 0.05) the thermal
resistance of C. botulinum 62A (type A), C. botulinum Okra (type B),
and C. sporogenes; reducing initial spore populations at 0.5-1.0% level
of addition. Further investigations showed that increasing acidity and
licorice extract (0.5%) had an additive heat- sensitizing effect on C.
botulinum 62A while increasing NaCl counteracted the effect of the
extract on the spores. Exposure of spores to 0.5% licorice extract for
7 d prior to heating significantly reduced the heat resistance of the
spores. Finally, a post-heating sporicidal property of licorice extract
was also observed, resulting in significantly greater spore population
reductions compared to that when licorice extract was removed by
washing with Tween 80 prior to enumeration on growth medium. The use of
naturally occurring compounds in plants as potential food additives may
help address the consumer demands for products with highly acceptable
sensory and nutritive qualities, and safety. (C) 2010 Elsevier Ltd. All
rights reserved.
UT WOS:000285661400017
SN 0956-7135
doi 10.1016/j.foodcont.2010.05.014

Publication type J
Title A Note on Lights-Out-Puzzle: Parity-State Graphs
Author/s Gervacio, SV Maehara, H
Vol 27
Issue 1
Start page 109
End page 119
Publication year 2011
Times cited 0
Abstract A state of a graph G is an assignment of 0 or 1 to each vertex of G. A
move of a state consists of choosing a vertex and then switching the
value of the vertex as well as those of its neighbors. Two states are
said to be equivalent if one state can be changed to the other by a
series of moves. A parity-state graph is defined to be a graph in which
two states are equivalent if and only if the numbers of 1’s in the two
states have the same parity. We characterize parity-state graphs and
present some constructions of parity-state graphs together with
applications. Among other things, it is proved that the one-skeleton of
the 3-polytope obtained from a simple 3-polytope by cutting off all
vertices is a parity-state graph.
UT WOS:000285152100007
SN 0911-0119
doi 10.1007/s00373-010-0958-1

Publication type J
Title A bioactive sesquiterpene from Bixa orellana
Author/s Raga, DD Espiritu, RA Shen, CC Ragasa, CY
Vol 65
Issue 1
Start page 206
End page 211
Publication year 2011
Times cited 0
Abstract A dichloromethane extract of the air-dried leaves of Bixa orellana
afforded ishwarane 1, phytol 2, polyprenol 3, and a mixture of
stigmasterol 4a and sitosterol 4b by silica gel chromatography. The
structure of 1 was elucidated by extensive 1D and 2D NMR spectroscopy.
Compound 1 at three doses (25, 50, and 100 mg/kg BW) was tested for
prophylactic, gastrointestinal motility, analgesic, hypoglycemic, and
antimicrobial potentials. Results of the prophylactic assay
demonstrated the anti-toxic property of 1 at 100 mg/kg BW. A 50 mg/kg
BW dose of 1 resulted in a more propulsive movement of the
gastrointestinal tract (88.38 +/- A 13.59%) compared to the negative
control (78.47 +/- A 10.61%). Tail flick and acetic acid writhing tests
indicated that 100 mg/kg BW 1 had minimal analgesic activity. Compound
1 demonstrated no hypoglycemic potential on the animals tested.
Compound 1 exhibited moderate antifungal activity against C. albicans,
low activity against T. mentagrophytes, and low antibacterial activity
against E. coli, S. aureus, and P. aeruginosa. It was inactive against
B. subtilis and A. niger.
UT WOS:000285156800033
SN 1340-3443
doi 10.1007/s11418-010-0459-9

Publication type J
Author/s Bermal, N Szenborn, L Alberto, E Hernandez, M Pejcz, J Majda-Stanislawska, E Gatchalian, S Fanic, A Dieussaert, I Schuerman, L
Vol 30
Issue 1
Start page 69
End page 72
Publication year 2011
Times cited 1
Abstract The safety and reactogenicity profiles of the 10-valent pneumococcal
conjugate vaccine, PHiD-CV, and 7vCRM were comparable within the
Philippines and Poland when coadministered as a booster dose with
DTPw-HBV/Hib and poliovirus vaccines to toddlers primed with the same
vaccines. Robust immune responses for all 10 vaccine pneumococcal
serotypes and protein D following PHiD-CV booster vaccination were
indicative of effective priming.
UT WOS:000285498800018
SN 0891-3668
doi 10.1097/INF.0b013e3181f2da06

Publication type J
Title Cross-national comparisons of socioeconomic differences in the
prevalence of leisure-time and occupational physical activity, and
active commuting in six Asia-Pacific countries
Author/s Bauman, A Ma, GS Cuevas, F Omar, Z Waqanivalu, T Phongsavan, P Keke, K Bhushan, A
Vol 65
Issue 1
Start page 35
End page 43
Publication year 2011
Times cited 0
Abstract Background This study describes physical activity patterns and their
association with socioeconomic factors in six countries in the
Asia-Pacific region, and examines whether physical activity
associations with socioeconomic status follow similar patterns across
the six countries.
Methods Population-wide representative surveys of non-communicable
disease risk factors and socioeconomic factors conducted in Australia,
China, Fiji, Malaysia, Nauru and the Philippines between 2002 and 2006
were used. Survey respondents aged 18-64 years who provided information
on their socioeconomic status (age, education, income, area of
residence) and physical activity level in three domains (leisure-time,
occupation, commuting) were included in the study (Australia N = 15
786; China N = 142 693; Fiji N = 6763; Malaysia N = 2572; Nauru N =
2085; Philippines N = 3307).
Results Leisure-time physical activity increased with age in China,
showed inverse associations for Fiji and Nauru men, and there were no
age relationships in other countries. Individuals in China, Fiji and
Malaysia living in urban areas, with higher educational attainment and
affluence were physically active during leisure time but less active at
work and during commuting compared to those in rural areas, with lower
educational attainment and lower income.
Conclusion There is a link between types of physical activity
participation and socioeconomic factors in developing countries.
Associations with socioeconomic indicators are likely to reflect
economic growth. The findings strongly support the need for a
comparable noncommunicable risk factors surveillance system in
developing countries.
UT WOS:000284938700008
SN 0143-005X
doi 10.1136/jech.2008.086710

Publication type J
Title Parameter extraction from I-V characteristics of PV devices
Author/s Macabebe, EQB Sheppard, CJ van Dyk, EE
Journal source SOLAR ENERGY
Vol 85
Issue 1
Start page 12
End page 18
Publication year 2011
Times cited 0
Abstract Device parameters such as series and shunt resistances, saturation
current and diode ideality factor influence the behaviour of the
current-voltage (I-V) characteristics of solar cells and photovoltaic
modules. It is necessary to determine these parameters since
performance parameters are derived from the I-V curve and information
provided by the device parameters are useful in analyzing performance
losses. This contribution presents device parameters of CuIn(Se,S)(2)-
and Cu(In,Ga)(Se,S)(2)-based solar cells, as well as, CuInSe2, mono-
and multicrystalline silicon modules determined using a parameter
extraction routine that employs Particle Swarm Optimization. The device
parameters of the CuIn(Se,S)(2)- and Cu(In,Ga)(Se,S)(2)-based solar
cells show that the contribution of recombination mechanisms exhibited
by high saturation current when coupled with the effects of parasitic
resistances result in lower maximum power and conversion efficiency.
Device parameters of photovoltaic modules extracted from I-V
characteristics obtained at higher temperature show increased
saturation current. The extracted values also reflect the adverse
effect of temperature on parasitic resistances. The parameters
extracted from I-V curves offer an understanding of the different
mechanisms involved in the operation of the devices. The parameter
extraction routine utilized in this study is a useful tool in
determining the device parameters which reveal the mechanisms affecting
device performance. (C) 2010 Elsevier Ltd. All rights reserved.
UT WOS:000286866500003
SN 0038-092X
doi 10.1016/j.solener.2010.11.005

Publication type J
Title Genetic Variation in Biomass Traits among 20 Diverse Rice Varieties
Author/s Jahn, CE Mckay, JK Mauleon, R Stephens, J McNally, KL Bush, DR Leung, H Leach, JE
Vol 155
Issue 1
Start page 157
End page 168
Publication year 2011
Times cited 0
Abstract Biofuels provide a promising route of producing energy while reducing
reliance on petroleum. Developing sustainable liquid fuel production
from cellulosic feedstock is a major challenge and will require
significant breeding efforts to maximize plant biomass production. Our
approach to elucidating genes and genetic pathways that can be targeted
for improving biomass production is to exploit the combination of
genomic tools and genetic diversity in rice (Oryza sativa). In this
study, we analyzed a diverse set of 20 recently resequenced rice
varieties for variation in biomass traits at several different
developmental stages. The traits included plant size and architecture,
aboveground biomass, and underlying physiological processes. We found
significant genetic variation among the 20 lines in all morphological
and physiological traits. Although heritability estimates were
significant for all traits, heritabilities were higher in traits
relating to plant size and architecture than for physiological traits.
Trait variation was largely explained by variety and breeding history
(advanced versus landrace) but not by varietal groupings (indica,
japonica, and aus). In the context of cellulosic biofuels development,
cell wall composition varied significantly among varieties.
Surprisingly, photosynthetic rates among the varieties were inversely
correlated with biomass accumulation. Examining these data in an
evolutionary context reveals that rice varieties have achieved high
biomass production via independent developmental and physiological
pathways, suggesting that there are multiple targets for biomass
improvement. Future efforts to identify loci and networks underlying
this functional variation will facilitate the improvement of biomass
traits in other grasses being developed as energy crops.
UT WOS:000285838300020
SN 0032-0889
doi 10.1104/pp.110.165654

Publication type J
Title Seeds of alpine plants are short lived: implications for long-term
Author/s Mondoni, A Probert, RJ Rossi, G Vegini, E Hay, FR
Journal source ANNALS OF BOTANY
Vol 107
Issue 1
Start page 171
End page 179
Publication year 2011
Times cited 0
Abstract Background and Aims Alpine plants are considered one of the groups of
species most sensitive to the direct and indirect threats to ecosystems
caused by land use and climate change. Collecting and banking seeds of
plant species is recognized as an effective tool for providing
propagating material to re-establish wild plant populations and for
habitat repair. However, seeds from cold wet environments have been
shown to be relatively short lived in storage, and therefore successful
long-term seed conservation for alpine plants may be difficult. Here,
the life spans of 69 seed lots representing 63 related species from
alpine and lowland locations from northern Italy are compared.
Methods Seeds were placed into experimental storage at 45 degrees C and
60% relative humidity (RH) and regularly sampled for germination. The
time taken in storage for viability to fall to 50% (p(50)) was
determined using probit analysis and used as a measure of relative seed
longevity between seed lots.
Key Results Across species, p50 at 45 degrees C and 60% RH varied from
4.7 to 95.5 d. Seed lots from alpine populations/species had
significantly lower p50 values compared with those from lowland
populations/species; the lowland seed lots showed a slower rate of loss
of germinability, higher initial seed viability, or both. Seeds were
progressively longer lived with increased temperature and decreased
rainfall at the collecting site.
Conclusions Seeds of alpine plants are short lived in storage compared
with those from lowland populations/related taxa. The lower resistance
to ageing in seeds of alpine plants may arise from low selection
pressure for seed resistance to ageing and/or damage incurred during
seed development due to the cool wet conditions of the alpine climate.
Long-term seed conservation of several alpine species using
conventional seed banking methods will be problematic.
UT WOS:000285413500014
SN 0305-7364
doi 10.1093/aob/mcq222

Publication type J
Title Characterization of mannose-binding protein isolated from the African
catfish (Clarias gariepinus B.) serum
Author/s Argayosa, AM Bernal, RAD Luczon, AU Arboleda, JS
Journal source AQUACULTURE
Vol 310
Issue 3-4
Start page 274
End page 280
Publication year 2011
Times cited 0
Abstract Lectins are carbohydrate-binding proteins which are involved in many
biological functions including cell adhesion, phagocytosis, complement
activation and innate immunity. This paper reports the first isolation
of mannose-binding protein (MBP), designated as CgMBP or kumpolin1,
from the serum of the African catfish, Clarias gariepinus (Burchell,
1822), a robust freshwater fish farmed extensively in Africa and South
East Asia. Mannan-agarose affinity column was used to purify the
mannose-binding protein from the serum. Molecular weight determination
using reducing SDS-PAGE and non-reducing SDS-PAGE analyses revealed a
single band close to 35 kDa and 28 kDa protein, respectively. Positive
microbial cell agglutination activities of the African catfish
mannose-binding protein were observed against Candida albicans,
Saccharomyces cerevisiae, Aeromonas hydrophila, Bacillus subtilis,
Enterococcus faecalis, Escherichia coil, and Pseudomonas aeruginosa.
The functional properties of the MBP were tested under various
conditions by using S. cerevisiae as the test organism. Agglutination
activity of MBP was found to occur at pH 3-7. It required 0.5 mM
calcium and was inhibited by 1 mM EDTA. (C) 2010 Elsevier B.V. All
rights reserved.
UT WOS:000286548300005
SN 0044-8486
doi 10.1016/j.aquaculture.2010.11.002

Publication type J
Title Renin-angiotensin system blockade and cognitive function in patients at
high risk of cardiovascular disease: analysis of data from the ONTARGET
and TRANSCEND studies
Author/s Anderson, C Teo, K Gao, P Arima, H Dans, A Unger, T Commerford, P Dyal, L Schumacher, HPogue, J Paolasso, E Holwerda, N Chazova, I Binbrek, A Young, J Yusuf, S
Vol 10
Issue 1
Start page 43
End page 53
Publication year 2011
Times cited 1
Abstract Background Cardiovascular risk factors are associated with dementia and
cognitive decline. We investigated the effects of renin-angiotensin
system blockade on cognitive function in patients aged 55 years and
older with established atherosclerotic cardiovascular disease or
diabetes with end-organ damage in two clinical trials.
Methods In the main study, ONTARGET, a double-blind, double-dummy,
randomised controlled trial, the effects on cardiovascular outcomes of
standard doses of an angiotensin-converting enzyme (ACE) inhibitor
(ramipril), an angiotensin-receptor blocker (telmisartan), and a
combination of the drugs were evaluated in 25 620 participants. In the
parallel TRANSCEND trial, the effects of telmisartan were compared with
those of placebo in 5926 participants intolerant to ACE inhibitors.
Secondary outcomes included cognitive impairment (defined by
investigator-reported diagnosis of dementia or significant cognitive
dysfunction, or a score of <= 23 on the Mini-Mental State Examination
[MMSE]) and cognitive decline (a decrease of points on the MMSE from
baseline during follow-up). Analyses were by intention to treat. We
pooled data from these studies to identify baseline predictors of
cognitive impairment and its frequency according to mean systolic blood
pressure during follow-up. These studies were registered with
ClinicalTrials.gov, number NCT00153101.
Findings During a median duration of 56 months (IQR 51-64) of follow-up
in ONTARGET, cognitive impairment occurred in 652 (8%) of 7865 patients
allocated ramipril, 584 (7%) of 7797 allocated telmisartan, and 618
(8%) of 7807 allocated combination treatment (combination vs ramipril,
odds ratio [OR] 0.95, 95% CI 0.85-1.07, p=0.39; telmisartan vs
ramipril, OR 0.90, 0.80-1.01, p=0.06). Corresponding figures for
cognitive decline were 1314 (17%), 1279 (17%), and 1240 (17%) in each
of the groups, respectively (telmisartan vs ramipril, OR 0.97,
0.89-1.06, p=0.53; combination vs ramipril, OR 0.95, 0.88-1.04,
p=0.28). In TRANSCEND, cognitive impairment occurred in 239 (9%) of
2694 participants allocated telmisartan compared with 245 (9%) of 2689
allocated placebo (OR 0.97, 0.81-1.17, p=0.76). The corresponding
figures for cognitive decline were 454 (17%) and 412 (16%; OR 1.10,
0.95-1.27, p=0. 22).
Interpretation In patients with cardiovascular disease or diabetes,
different approaches to blocking of the renin-angiotensin system had no
dear effects on cognitive outcomes. Although patients with the lowest
systolic blood pressure had the greatest preservation of cognitive
function, meta-regression analyses did not show any benefits of
blood-pressure lowering on cognition over several years of treatment.
UT WOS:000285810100018
SN 1474-4422
doi 10.1016/S1474-4422(10)70250-7

Publication type J
Title The versatile, changing, and advancing roles of fish in sediment
toxicity assessment-a review
Author/s Hallare, AV Seiler, TB Hollert, H
Vol 11
Issue 1
Start page 141
End page 173
Publication year 2011
Times cited 1
Abstract Purpose Sediments serve as integral and dynamic parts of our aquatic
systems. Within the last 15 to 20 years, however, the scientific
community has begun noticing deterioration of sediment quality at an
alarming rate worldwide. Sediments are now harboring hazardous
pollutants that can directly influence water quality, thereby creating
very stressful conditions for aquatic life. As a consequence, global
efforts were initiated in the early 1970s, to find ways to assess
sediment quality. Because of their obvious ecological and economic
significance, fish have remained a major taxonomic group for appraising
the general quality of aquatic systems. However, for sediment risk
assessment, fish have lagged behind invertebrates due to their mobility
and generally, pelagic lifestyle. To our knowledge, this is the first
paper that comprehensively presents and reviews the versatile role of
fish in assessing the state of health of aquatic sediments.
Main features Through a literature search of the more relevant and/or
more recent studies, this review attempted to trace the development of
the various approaches as well as to describe the future prospects of
using fish as sentinels for sediment quality assessment. Initially, the
use of whole fish (juveniles or adults) bioassays contributed immensely
to our understanding of sediment contamination and ecotoxicology. But
due to economic as well as ethical issues linked to the use of live
vertebrates for toxicity testing, the approach has shifted to using
fish cell cultures and fish embryos. Much newer approaches involving
receptors and gene arrays in fish cells to elucidate the mode of action
of sediment-borne contaminants are very promising. The review paper
also lists and explores some of the issues associated with the use of
juvenile or adult fish, fish cell cultures, fish embryos, and fish gene
expression profiles in sediment toxicity evaluations to stimulate
further discussions, and hopefully, to serve as benchmark for future
handling of similar or related aspects of fish utilization in sediment
risk assessment.
Conclusions and perspectives Overall, the present review has
comprehensively explored the changing and progressing roles of fish in
sediment toxicity evaluation. Indeed the usefulness of this taxon as
test organisms has provided a significant contribution to the
advancement of sediment toxicology. However, despite the quite
optimistic and bright future for these current procedures, a number of
issues and problems remain. Therefore, efforts to develop new
technologies and to refine current methods and approaches continue to
challenge many laboratories worldwide.
UT WOS:000286527400014
SN 1439-0108
doi 10.1007/s11368-010-0302-7

Publication type J
Title Pathogen dynamics in a crop canopy and their evolution under changing
Author/s Pangga, IB Hanan, J Chakraborty, S
Journal source PLANT PATHOLOGY
Vol 60
Issue 1
Start page 70
End page 81
Publication year 2011
Times cited 2
Abstract Canopy-level interactions have been largely ignored in epidemiological
models and their applications in defining disease risks under climate
change, although these interactions are important for disease
management. This paper uses anthracnose of Stylosanthes scabra as a
case study and reviews research on dynamics of the pathogen
(Colletotrichum gloeosporioides) at the canopy level and pathogen
evolution under changing climate. It argues that linking of pathogen
dynamics, crop growth and climate models is essential in predicting
disease risks under climate change. A plant functional-structural model
was used to couple S. scabra growth and architecture with disease under
ambient and elevated CO2. A level of induced resistance in plants with
enlarged canopy determined anthracnose severity at elevated CO2.
Moisture-related microclimatic variables determined infection at
ambient but not at elevated CO2. At high CO2 increased disease level
from raised pathogen fecundity in enlarged canopy accelerated pathogen
evolution after 25 sequential infection cycles. Modelling of pathogen
dynamics under climate change currently suffers from a paucity of
quantitative data, mismatch of scales in coupling climate and disease
models, and model uncertainties. Further experimental research on
interactions of biotic and abiotic factors on plant diseases under
climate change and validation of models are essential prior to their
use in climate-change prediction. Understanding and anticipating trends
in host-pathogen evolution under climate change will improve the
durability of resistance and lay the foundation for increased crop
adaptation through pre-emptive plant breeding.
UT WOS:000286114700007
SN 0032-0862
doi 10.1111/j.1365-3059.2010.02408.x

Publication type J
Title Complexity in climate-change impacts: an analytical framework for
effects mediated by plant disease
Author/s Garrett, KA Forbes, GA Savary, S Skelsey, P Sparks, AH Valdivia, C van Bruggen, AHC Willocquet, LDjurle, A Duveiller, E Eckersten, H Pande, S Cruz, CV Yuen, J
Journal source PLANT PATHOLOGY
Vol 60
Issue 1
Start page 15
End page 30
Publication year 2011
Times cited 1
Abstract The impacts of climate change on ecosystem services are complex in the
sense that effective prediction requires consideration of a wide range
of factors. Useful analysis of climate-change impacts on crops and
native plant systems will often require consideration of the wide array
of other biota that interact with plants, including plant diseases,
animal herbivores, and weeds. We present a framework for analysis of
complexity in climate-change effects mediated by plant disease. This
framework can support evaluation of the level of model complexity
likely to be required for analysing climate-change impacts mediated by
disease. Our analysis incorporates consideration of the following set
of questions for a particular host, pathogen, host-pathogen
combination, or geographic region. 1. Are multiple biological
interactions important? 2. Are there environmental thresholds for
population responses? 3. Are there indirect effects of global change
factors on disease development? 4. Are spatial components of epidemic
processes affected by climate? 5. Are there feedback loops for
management? 6. Are networks for intervention technologies slower than
epidemic networks? 7. Are there effects of plant disease on multiple
ecosystem services? 8. Are there feedback loops from plant disease to
climate change? Evaluation of these questions will help in gauging
system complexity, as illustrated for fusarium head blight and potato
late blight. In practice, it may be necessary to expand models to
include more components, identify those components that are the most
important, and synthesize such models to include the optimal level of
complexity for planning and research prioritization.
UT WOS:000286114700003
SN 0032-0862
doi 10.1111/j.1365-3059.2010.02409.x

Publication type J
Title Socio-cultural context of fishers’ participation in coastal resources
management in Anini-y, Antique in west central Philippines
Author/s Aldon, MET Fermin, AC Agbayani, RF
Vol 107
Issue 1-3
Start page 112
End page 121
Publication year 2011
Times cited 0
Abstract The vicious cycle of poverty, overfishing and resource degradation in
coastal communities in the Philippines calls for action that will
address the problem of declining fish catch and degraded fish habitats.
The literature has shown that an efficient and effective coastal
management program can be instrumental in approaching this problem. In
order to secure food and livelihood of fishers, the Southeast Asian
Fisheries Development Center/Aquaculture Department collaborated with
the local government of Anini-y. Antique to develop a sustainable
utilization of natural marine resources through sea ranching of abalone
within the Nogas Island marine protected area. Establishing a marine
protected area is a means of conserving natural stocks while sea
ranching is considered an effective strategy that can increase fishery
resources. The two management schemes are considered as effective
coastal resources management strategies. The success of a sea-ranching
project is dependent not only on biophysical but also on socioeconomic
factors as determinants of community participation and cooperation. A
social assessment was conducted to determine the fishers’
socio-cultural characteristics, their perceptions of their coastal
resources and knowledge on how to effectively manage these coastal
resources. The fishers’ awareness on fishing regulations and the extent
of their participation in community’s coastal resources management
activities were also determined. Data were collected from a household
survey using a semi-structured questionnaire, focus group discussions
and in-depth interviews with key informants. The fishers generally
scored low in almost all aspects of their socioeconomic wellbeing. Most
fishers perceived that their coastal resources were in a bad condition
which they attributed to illegal and commercial fishing, increasing
number of fishers and the poor enforcement of fishery regulations.
However, the weighted mean scores of their knowledge on coastal
resources management, awareness to fishery regulations and
participation in community coastal resource management activities were
average. This implied that fishers when trained and developed can
become potential partners for effective coastal resources management
programs. (C) 2010 Elsevier B.V. All rights reserved.
UT WOS:000287113600012
SN 0165-7836
doi 10.1016/j.fishres.2010.10.014

Publication type J
Title Characterization of Rice Blast Isolates by the Differential System and
their Application for Mapping a Resistance Gene, Pi19(t)
Author/s Koide, Y Telebanco-Yanoria, MJ Dela Pena, F Fukuta, Y Kobayashi, N
Vol 159
Issue 2
Start page 85
End page 93
Publication year 2011
Times cited 0
Abstract To facilitate resistance gene characterization in the present study,
the pathogenicities of newly collected blast isolates from rice fields
in the Philippines were characterized using international blast
differential varieties consisting of 31 monogenic lines that target 24
resistance genes. To classify and designate the blast isolates, we used
a new international blast designation system, which has been proposed
as a suitable naming system for comparing blast races among different
studies. A total of 23 rice blast isolates collected from the
Philippines were classified into 16 pathotypes, which showed reaction
patterns different from those seen in the standard isolates. Among the
blast pathotypes, 11 had differentiating ability for four Pik alleles
(Pik, Pik-m, Pik-h, and Pik-p) and Pi1, whereas the standard blast
isolates from the Philippines were not able to differentiate these
genes. In addition, several blast isolates were avirulent to IRBLt-K59,
IRBL19-A, and Lijiangxintuanheigu, although the standard differential
blast isolates were virulent to these lines. Moreover, two blast
isolates were virulent to a monogenic line, IRBL9-W, which harbours Pi9
and was resistant to all standard differential blast isolates. By using
the isolates avirulent to IRBL19-A, Pi19(t) was successfully mapped in
the centromeric region on chromosome 12 with simple sequence repeat
markers RM27937 and RM1337. These markers are useful for
marker-assisted Pi19(t) introgression worldwide.
UT WOS:000285968400003
SN 0931-1785
doi 10.1111/j.1439-0434.2010.01721.x

Publication type J
Author/s Hufana-Duran, D Duran, PG Atabay, EP Kanai, Y Takahashi, Y Cruz, LC
Vol 23
Issue 1
Start page 101
Publication year 2011
Times cited 0
UT WOS:000285008200114
SN 1031-3613

Publication type J
Title Organochlorine Pesticides in Ambient Air in Selected Urban and Rural
Residential Areas in the Philippines Derived from Passive Samplers with
Polyurethane Disks
Author/s Santiago, EC Cayetano, MG
Vol 86
Issue 1
Start page 50
End page 55
Publication year 2011
Times cited 0
Abstract The passive sampler with PUF disk was applied to investigate the types
and concentrations of organochlorine pesticides (OCPs) in ambient air
in three urban and rural residential areas simultaneously at different
weather conditions in the Philippines. The concentrations of OCPs
derived from the passive samplers indicated clear distinctions in the
predominance of certain types and amounts of OCPs in air at different
sampling sites and periods of sampling. Chlordanes were detected in
concentrations ranging from 218 to 2,324 pg/m(3) in the urban
residential sites in all the sampling periods, indicating the possible
use of these pesticides as termiticides in houses. Endosulfans were
detected in two rural sites at 491 pg/m(3) and 904 pg/m(3) during one
sampling period; indicating the possible use of the pesticide in the
farm areas at that period.
UT WOS:000285999900008
SN 0007-4861
doi 10.1007/s00128-010-0160-4

Publication type J
Title Detection of Drought-Related Loci in Rice at Reproductive Stage Using
Selected Introgressed Lines
Author/s Chen, MY Ali, J Fu, BY Xu, JL Zhao, MF Jiang, YZ Zhu, LH Shi, YY Yao, DN Gao, YM Li, ZK
Vol 10
Issue 1
Start page 1
End page 8
Publication year 2011
Times cited 0
Abstract The present study was carried out to illustrate high-efficient
detection of quantitative trait loci (QTLs) with selected introgression
lines (ILs) and the existence of ‘hidden genes’ conferring drought
tolerance (DT). 52 selected DT ILs, derived from BC2F2 population
developed by crossing and backcrossing the susceptible recurrent parent
(RP) IR64 with the susceptible donor Khazar were planted under
irrigation and drought condition. Four important agronomic traits,
e.g., grain yield (GY), heading date (HD), panicle numbers per plant
(PN), and plant height (PH) were evaluated and 83 SSR polymorphic
molecular markers were used for genotypic analysis. Chi-square test
based on genetic hitch-hiking and one-way analysis of variances (ANOVA)
were used to detect drought-related loci. Nine and 36 loci were
detected by chi-square test and one-way ANOVA, respectively. Five
common loci were observed by comparing the results of the two methods,
among which two QTLs linked with RM7, and RM241 were detected under
irrigation condition, both of the favorable alleles were from RP and
explained 13% phenotypic variation (PV) for GY and 28% PV for PH,
respectively. The other three QTLs linked with RM163, RM18, and RM270
were detected under drought condition, the favorable alleles were all
from the donor and explained 10, 24, and 19% PV for HD, PH, and PH,
respectively. Five common loci were observed by comparing the results
of chi-square test and one-way ANOVA including two QTLs (one for GY and
one for PH) under irrigation condition and three QTLs (one for HD and
two for PH) under drought condition. By combining phenotypic and
genotypic analysis, drought escape could be inferred as the main
mechanism for drought tolerance in the present study. The results in
present study suggested that the selected ILs population analyzed by
chi-square test and one-way ANOVA was quite effective for DT QTL
detection with low inputs and could also produce useful materials for
breeding with wide genetic diversity for drought tolerance.
UT WOS:000286360000001
SN 1671-2927
doi 10.1016/S1671-2927(09)60284-4

Publication type J
Title The Y-chromosome landscape of the Philippines: extensive heterogeneity
and varying genetic affinities of Negrito and non-Negrito groups
Author/s Delfin, F Salvador, JM Calacal, GC Perdigon, HB Tabbada, KA Villamor, LP Halos, SCGunnarsdottir, E Myles, S Hughes, DA Xu, SH Jin, L Lao, O Kayser, M Hurles, ME Stoneking, MDe Ungria, MCA
Vol 19
Issue 2
Start page 224
End page 230
Publication year 2011
Times cited 2
Abstract The Philippines exhibits a rich diversity of people, languages, and
culture, including so-called ‘Negrito’ groups that have for long
fascinated anthropologists, yet little is known about their genetic
diversity. We report here, a survey of Y-chromosome variation in 390
individuals from 16 Filipino ethnolinguistic groups, including six
Negrito groups, from across the archipelago. We find extreme diversity
in the Y-chromosome lineages of Filipino groups with heterogeneity seen
in both Negrito and non-Negrito groups, which does not support a simple
dichotomy of Filipino groups as Negrito vs non-Negrito. Filipino
non-recombining region of the human Y-chromosome lineages reflect a
chronology that extends from after the initial colonization of the
Asia-Pacific region, to the time frame of the Austronesian expansion.
Filipino groups appear to have diverse genetic affinities with
different populations in the Asia-Pacific region. In particular, some
Negrito groups are associated with indigenous Australians, with a
potential time for the association ranging from the initial
colonization of the region to more recent (after colonization) times.
Overall, our results indicate extensive heterogeneity contributing to a
complex genetic history for Filipino groups, with varying roles for
migrations from outside the Philippines, genetic drift, and admixture
among neighboring groups. European Journal of Human Genetics (2011) 19,
224-230; doi:10.1038/ejhg.2010.162; published online 29 September 2010
UT WOS:000286176500018
SN 1018-4813
doi 10.1038/ejhg.2010.162

Publication type J
Title Comment on: ‘Rabies and African bat lyssavirus encephalitis and its
Author/s Briggs, DJ Wilde, H Hemachuda, T Shantavasinkul, P Quiambao, B Sudarshan, MK Madhusudana, SN
Vol 37
Issue 2
Start page 182
End page 183
Publication year 2011
Times cited 1
UT WOS:000286198900021
SN 0924-8579
doi 10.1016/j.ijantimicag.2010.09.014

Publication type J
Title Knowledge, attitudes and practices of farmers on rodent pests and their
management in the lowlands of the Sierra Madre Biodiversity Corridor,
Author/s Stuart, AM Prescott, CV Singleton, GR Joshi, RC
Journal source CROP PROTECTION
Vol 30
Issue 2
Start page 147
End page 154
Publication year 2011
Times cited 0
Abstract A survey of the knowledge, attitudes and practices (KAP) of 100 rice
farmers and 50 coconut farmers was conducted in the coastal lowland
agro-ecosystems of the Sierra Madre Biodiversity Corridor, Luzon,
Philippines to identify current rodent management practices and to
understand the extent of rat damage and the attitudes of farmers to
community actions for rodent management. Pests were most commonly
listed as one of the three most important rice and coconut production
constraints. Other major crop production constraints were typhoons and
insufficient water. Farmers consider rats to be the major pest of
coconut and of rice during the wet season rice crop, with average yield
losses of 3.0% and 13.2%, respectively. Rice and coconut farmers
practised a wide range of rodent management techniques. These included
scrub clearance, hunting and trapping. Of the 42 rice farmers and 3
coconut farmers that applied rodenticides to control rodents, all used
the acute rodenticide, zinc phosphide. However, only ten rice farmers
(23.8%) applied rodenticides prior to the booting stage and only seven
farmers (15.6%) conducted pre-baiting before applying zinc phosphide.
The majority of farmers belonged to farmer organisations and believed
that rat control can only be done by farmers working together. However,
during the last cropping season, less than a third of rice farmers
(31.2%) applied rodent management as a group. In order to reduce the
impact of rodents on the farmers of the coastal lowlands of the Sierra
Madre Biodiversity Corridor, integrated management strategies need to
be developed that specifically target the pest rodents in a sustainable
manner, and community actions for rodent management should be promoted.
(C) 2010 Elsevier Ltd. All rights reserved.
UT WOS:000286957800009
SN 0261-2194
doi 10.1016/j.cropro.2010.10.002

Publication type J
Title Characterizing multiple linkages between individual diseases, crop
health syndromes, germplasm deployment, and rice production situations
in India
Author/s Reddy, CS Laha, GS Prasad, MS Krishnaveni, D Castilla, NP Nelson, A Savary, S
Vol 120
Issue 2
Start page 241
End page 253
Publication year 2011
Times cited 0
Abstract Five groups of crop health syndromes, four production situations, and
three patterns of germplasm deployment were identified and
characterized from a data set consisting of information from 129 Indian
districts, which were surveyed in 2005 as part of the
Production-Oriented Surveys conducted by the Directorate of Rice
Research of the Indian Council of Agricultural Research. ANOVAs and
MANOVAs indicated that these groupings from hierarchical cluster
analyses correspond to clearly different levels of disease and animal
pest injuries (crop health syndromes): of crop rotation, crop
management, agricultural resources, and inputs (production situations):
and of deployment of traditional, high yielding, or hybrid plant
material (patterns of germplasm deployment). Correspondence analysis
and discriminant analyses further indicated that crop health syndromes,
and their change, are strongly associated with production situations,
and patterns of germplasm deployment. A few specific hypotheses were
tested, indicating that false smut is statistically associated with the
involvement of hybrid rice in patterns of germplasm deployment. This
highlights the need for research on the biology and the epidemiology of
this disease in order to develop suitable management tools.
Importantly, this work shows that national surveys, such as the
Production-Oriented Surveys conducted by the Directorate of Rice
Research, generate extremely valuable information to guide research and
development through the characterization of production environments,
contexts, and crop health responses, in times of unprecedented
agricultural change. This work concurs with earlier results obtained at
the field level, and thus opens important methodological questions
regarding the up- and down-scaling of information between different
scales (e.g., field, district). We propose that our ability to predict
emerging diseases and crop health syndromes in the face of global and
climate change will necessarily entail our ability to link different
scales, where a range of different processes, biological and
socio-economic, take place. (C) 2010 Elsevier B.V. All rights reserved.
UT WOS:000286856400005
SN 0378-4290
doi 10.1016/j.fcr.2010.10.005

Publication type J
Title Variation in root system architecture and drought response in rice
(Oryza sativa): Phenotyping of the OryzaSNP panel in rainfed lowland
Author/s Henry, A Gowda, VRP Torres, RO McNally, KL Serraj, R
Vol 120
Issue 2
Start page 205
End page 214
Publication year 2011
Times cited 1
Abstract Root growth at soil depths below 30 cm may provide access to critical
soil water reserves during drought in rainfed lowland rice. In this
study, the OryzaSNP panel, a set of 20 lines representing genetic
diversity in rice used for the discovery of DNA sequence polymorphisms,
was evaluated for root characteristics in the field over three seasons
varying in drought severity. Root length density (RLD) at a depth of
30-45 cm varied up to 74-92% among genotypes under drought stress
(2008-2009 dry seasons), ranging from 0.024 to 0.23 cm cm(-3) in 2008
and from 0.19 to 0.81 cm cm(-3) in 2009. Real-time monitoring of soil
moisture profiles revealed significant differences among genotypes, and
these differences were correlated with RLD at those soil depths. Among
the lines evaluated, the Aus isozyme group, particularly the genotype
Dular, showed greater drought resistance associated with deep root
growth and the highest drought response index (less reduction in yield
by drought stress). Since the set of genotypes used in this study has
been completely sequenced for SNP markers, the phenotypic information
on root growth and drought avoidance responses presented here could be
used in initial analysis of the genetic basis of dehydration avoidance
traits and in facilitating improvement in drought resistance in rice.
(C) 2010 Elsevier B.V. All rights reserved.
UT WOS:000286856400001
SN 0378-4290
doi 10.1016/j.fcr.2010.10.003

Publication type J
Title Development of elite breeding lines conferring Bph18 gene-derived
resistance to brown planthopper (BPH) by marker-assisted selection and
genome-wide background analysis in japonica rice (Oryza sativa L.)
Author/s Suh, JP Yang, SJ Jeung, JU Pamplona, A Kim, JJ Lee, JH Hong, HC Yang, CI Kim, YG Jena, KK
Vol 120
Issue 2
Start page 215
End page 222
Publication year 2011
Times cited 0
Abstract Brown planthopper (BPH) is a serious threat to rice production. In this
study, we have used the novel resistance gene Bph18 derived from Oryza
australiensis and incorporated it into an elite japonica cultivar,
Junambyeo, which is highly susceptible to BPH. The Bph18 gene was
introduced by marker-assisted backcross (MAB) breeding into Junambyeo.
The backcrossed progenies were evaluated for desirable agronomic and
grain quality traits and the selection of improved breeding lines while
simultaneously evaluating BPH resistance by bioassays in the greenhouse
and foreground selection. Of the 26 advanced backcross breeding lines
(ABL), four lines showed agronomic traits similar to those of the
recurrent parent, with strong resistance to BPH. Molecular genotyping
of the four ABL revealed the conversion of genotypes closely resembling
the genotype of Junambyeo. The percentage of donor chromosome segments
in ABL decreased from 12.3% in the BC2 to 9.4%, 8.4% and 5.3% in BC3,
BC4 and BC5 generations, respectively. ABL retained small sizes of the
donor chromosome segments on chromosomes 1, 2, 10, 11 and 12 but the
genomes of ABL2, ABL3 and ABL4 were homosequential to the recurrent
parent on chromosomes 3, 4, 5, 6, 7 and 9 without donor chromosome
segment introgression. The ABL1 and ABL2 retained only some small
segments of the donor genome on chromosomes 9 and 8. respectively. Fine
structure analysis of the Bph18 flanking region between RM511 and
RM1584 markers on chromosome 12 showed a progressive elimination of
donor-derived chromosome segments from BC2 to BC5 generations. The
percentage of O. australiensis derived chromosome segment substitution
in the recurrent parent background decreased from 28% of the donor
parent to 6.7%, 3.9%, 3.4% and 3.4% in BC2, BC3, BC4 and BC5
generations, respectively. However, it was revealed that the O.
australiensis-derived chromosome segment (1320 kb) in ABL containing
the Bph18 gene was consistently maintained irrespective of advances in
backcross generations. BPH resistant elite breeding lines with
agronomic and grain quality traits similar to those of the recurrent
parent were successfully developed by foreground and background
analysis in japonica background without linkage drag. (C) 2010 Elsevier
B.V. All rights reserved.
UT WOS:000286856400002
SN 0378-4290
doi 10.1015/j.fcr.2010.10.004

Publication type J
Title Hamiguitan Range: A sanctuary for native flora
Author/s Amoroso, VB Aspiras, RA
Vol 18
Issue 1
Start page 7
End page 15
Publication year 2011
Times cited 0
Abstract Hamiguitan Range is one of the wildlife sanctuaries in the Philippines
having unique biodiversity resources that are at risk due to forest
degradation and conversion of forested land to agriculture, shifting
cultivation, and over-collection. Thus, it is the main concern of this
research to identify and assess the endemic and endangered flora of
Hamiguitan Range. Field reconnaissance and transect walk showed five
vegetation types namely: agro-ecosystem, dipterocarp, montane, typical
mossy and mossy-pygmy forests. Inventory of plant species revealed 163
endemic species, 35 threatened species, and 33 rare species. Assessment
of plants also showed seven species as new record in Mindanao and one
species as new record in the Philippines. Noteworthy is the discovery
of Nepenthes micramphora, a new species of pitcher plant found in the
high altitudes of Hamiguitan Range. This species is also considered
site endemic, rare, and threatened. The result of the study also showed
that the five vegetation types of Mt. Hamiguitan harbor a number of
endangered, endemic, and rare species of plants. Thus, the result of
this study would serve as basis for the formulation of policies for the
protection and conservation of these species and their habitats before
these plants become extinct. (C) 2010 King Saud University. All rights
UT WOS:000286426600002
SN 1319-562X
doi 10.1016/j.sjbs.2010.07.003

Publication type J
Title -174G > C interleukin-6 gene polymorphism in Tunisian patients with
coronary artery disease
Author/s Ghazouani, L Abboud, N Khalifa, SB Added, F Ben Khalfallah, A Nsiri, B Mediouni, M Mahjoub, T
Vol 31
Issue 1
Start page 40
End page 44
Publication year 2011
Times cited 0
Abstract BACKGROUND AND OBJECTIVES: A state of low-grade inflammation
accompanies the pathogenesis of atherosclerotic events. Interleukin-6
(IL-6) is a pleotropic pro-inflammatory cytokine that modulates the
development of acute coronary syndromes (ACSs), partly by destabilizing
coronary atherosclerotic plaques. We have examined the contribution of
the -174G>C IL-6 promoter variant on the risk of coronary artery
disease (CAD) among Tunisians.
PATIENTS AND METHODS: Study subjects included 418 CAD patients and 406
age-and sex-matched controls. IL-6 genotyping was done by
PCR-restriction fragment length polymorphism.
RESULTS: The frequency of the -174C allele (mutant) was lower in
Tunisians than in Europeans, and the distribution of -174G>C genotypes
was similar between CAD patients and control subjects. Moreover,
compared to GG genotype carriers, -174C allele carriage did not
increase the CAD relative risk (odds ratio and 95% confidence
interval=1.09 and 0.80-1.49), which remained nonsignificant after
adjusting for traditional risk factors for CAD (age, smoking,
hypertension, diabetes and obesity).
CONCLUSION: The -174G>C IL-6 promoter variant is not associated with an
increased risk of CAD among Tunisians.
UT WOS:000286609200008
SN 0256-4947
doi 10.4103/0256-4947.75777

Publication type J
Title Comparative and competitive adsorption of copper, lead, and nickel
using chitosan immobilized on bentonite
Author/s Futalan, CM Kan, CC Dalida, ML Hsien, KJ Pascua, C Wan, MW
Vol 83
Issue 2
Start page 528
End page 536
Publication year 2011
Times cited 0
Abstract The comparative and competitive adsorption of Cu(II) Ni(II) and Pb(II)
from aqueous solution using chitosan immobilized on bentonite (CHB) was
investigated The adsorption data of single and binary systems indicated
that Cu(II) and Pb(II) best fits Freundlich isotherm while NI(II)
follows Langmuir In binary systems a decrease in adsorption capacities
and isotherm constants was observed showing preference of adsorption in
the order of Pb(II) > Cu(II) > Ni(II) Kinetic studies of single system
indicated that the pseudo-second order is the best fit with high
correlation coefficients (R-2 > 099) and low sum of error values (SE =
0 13-0 46%) Thermodynamic studies illustrated that adsorption of CHB
are exothermic and causes a decrease in the entropy The adsorption of
Pb(II) is spontaneous while Ni(11) is non-spontaneous at 25-55 C Cu(II)
adsorption is only spontaneous at 25 C (C) 2010 Elsevier Ltd All rights
UT WOS:000285437000029
SN 0144-8617
doi 10.1016/j.carbpol.2010.08.013

Publication type J
Title Fixed-bed column studies on the removal of copper using chitosan
immobilized on bentonite
Author/s Futalan, CM Kan, CC Dalida, ML Pascua, C Wan, MW
Vol 83
Issue 2
Start page 697
End page 704
Publication year 2011
Times cited 0
Abstract The use of chitosan immobilized on bentonite (CHB) in the removal of
Cu(II) from aqueous solutions was investigated using a column system
The effect on the time of breakthrough and uptake capacity of the
column was examined The dynamics of the adsorption process were
evaluated by using bed depth service time (BDST) model and Thomas model
The adsorption capacity of 14 92 mg Cu(II)/g CHB with 24 h breakthrough
was achieved at 500 mg/L of initial concentration bed height of 4 3 cm
and flow rate of 020 mL/min The time of breakthrough decreases while
breakthrough curves become sharper with increase in flow rate and
influent concentration and a decrease in bed height of the adsorbent
Moreover Thomas model was an acceptable kinetic model The BDST model
was utilized to compute dynamic bed capacity (N-0) adsorption rate
constant (k(ads)) and critical bed depth (Z(0)) at 29 94 g/L 0 000857
L/(mg h) and 0 9187 cm respectively (C) 2010 Elsevier Ltd All rights
UT WOS:000285437000052
SN 0144-8617
doi 10.1016/j.carbpol.2010.08.043

Publication type J
Title Shifting trends in in vitro antibiotic susceptibilities for common
bacterial conjunctival isolates in the last decade at the New York Eye
and Ear Infirmary
Author/s Adebayo, A Parikh, JG McCormick, SA Shah, MK Huerto, RS Yu, GP Milman, T
Vol 249
Issue 1
Start page 111
End page 119
Publication year 2011
Times cited 0
Abstract Bacterial conjunctivitis is one of the most common forms of ocular
diseases worldwide. The purpose of this study is to determine the most
common pathogens causing bacterial conjunctivitis, their in vitro
susceptibility to existing antibiotics, and the changing trends in
bacterial resistance to antibiotics over the last decade.
Records of all conjunctival bacterial cultures performed at the NYEEI
Microbiology Laboratory from 1 January 1997 through 30 June 2008 were
reviewed. Data on species of bacterial isolates and their in vitro
susceptibility to the antibiotics tetracycline,
trimethaprim/sulfamethoxazole (TMP/SMZ), imipenem, fluoroquinolones
(ciprofloxacin, moxifloxacin, gatifloxacin), aminoglycosides
(gentamicin, tobramycin), erythromycin, cefazolin, oxacillin, and
vancomycin were collected.
Review of records yielded 20,180 conjunctival bacterial cultures, 60.1%
of which were culture-positive. Of the culture-positive isolates, 76.6%
were gram-positive and 23.4% were gram-negative pathogens.
Staphylococcus aureus was the most common gram-positive pathogen
isolated, and also the most commonly isolated pathogen overall.
Haemophilus influenzae was the most common gram-negative pathogen. A
significant increase in the percentage of methicillin-resistant
Staphylococcus aureus (MRSA) was observed in the course of 11.5 years.
The highest levels of antibiotic resistance were observed to
tetracycline, erythromycin, and TMP/SMZ. Gram-positive isolates were
least resistant to vancomycin, and gram-negative isolates were least
resistant to imipenem. The lowest broad-spectrum antibiotic resistance
was observed in the case of moxifloxacin, gatifloxacin, and
Staphylococcus aureus is the most common pathogen in bacterial
conjunctivitis. Conjunctival bacterial isolates demonstrated high
levels of resistance to tetracycline, erythromycin and TMP/SMZ.
Moxifloxacin and gatifloxacin appear to be currently the best choice
for empirical broad-spectrum coverage. Vancomycin is the best
antibiotic for MRSA coverage.
UT WOS:000286608700014
SN 0721-832X
doi 10.1007/s00417-010-1426-6

Publication type J
Title BM-ca is a newly defined type I/II anti-CD20 monoclonal antibody with
unique biological properties
Author/s Nishida, M Uematsu, N Kobayashi, H Matsunaga, Y Ishida, S Takata, M Niwa, O Padlan, EA Newman, R
Vol 38
Issue 2
Start page 335
End page 344
Publication year 2011
Times cited 0
Abstract Rituximab (chimeric anti-CD20 mAb) is currently used in the treatment
of B-NHL and B cell malignancies, alone or in combination with
chemotherapy. However, subsets of patients do not initially respond
and/or develop resistance to additional treatments. Hence, there is a
need to develop more effective anti-CD20 mAbs that may improve clinical
response. BM-ca is a novel humanized anti-CD20 mAb that was tested
against several B-NHL cell lines and was compared to several anti-CD20
mAbs (Rituximab, ofatumumab, 2H7, B1 and B-Ly1). BM-ca was shown to
strongly induce both homotypic cell aggregation and redistribution of
CD20 to membrane lipid rafts. BM-ca was also able to induce programmed
cell death (apoptosis) without the need for cross-linking and
demonstrated potent complement-dependent cytotoxicity (CDC). BM-ca was
more cytotoxic than rituximab even in malignant B cells expressing low
amounts of membrane CD20. Type I anti-CD20 mAbs typically induce
minimal levels of homotypic cell aggregation and apoptosis but strong
localization of CD20 to lipid rafts and potent CDC. Type II anti-CD20
mAbs typically exert the reverse activities. Noteworthy, BM-ca exhibits
properties that are shared by both type I and type II anti-CD20 mAbs,
which may reflect the recognition of a new CD20 epitope and/or exhibit
different molecular signaling. Overall, the present data show that
BM-ca is a novel anti-CD20 mAb that may be classified as a type I/II.
The therapeutics efficacy of BM-ca awaits its use in clinical trials.
UT WOS:000286702600005
SN 1019-6439
doi 10.3892/ijo.2010.864

Publication type J
Title Kinetics of absorption of carbon dioxide in 2-amino-2-methyl-l-propanol
plus N-methyldiethanolamine plus water
Author/s Huang, YM Soriano, AN Caparanga, AR Li, MH
Vol 42
Issue 1
Start page 76
End page 85
Publication year 2011
Times cited 0
Abstract The rate at which CO2 is absorbed in the solvent system 2-amino-2-methyl-l-propanol (AMP) + N-methyldiethanolamine (MDEA) + H2O was determined at 30, 35, and 40 degrees C in a wetted-wall column. Ten
different concentrations of the solvent system were used in which MDEA concentration was varied as 1.0 and 1.5 kmol m(-3); that of AMP, as 0.1, 0.2, 0.3, 0.4, and 0.5 kmol m(-3). The overall pseudo-first order
reaction rate constants for the CO2 absorption estimated from the kinetics data are presented. Data suggest that a small increase in AMP concentration at fixed MDEA concentration in the solvent system will result in significant increase on the rate of CO2 absorption. The absorption was described in terms of a hybrid reaction rate model,
which assumed a second-order reaction (CO2 + MDEA) and a zwitterion mechanism for the reaction between CO2 and AMP. The apparent rate constants estimated from the measurements were compared to the corresponding values predicted from the model; the result was satisfactory, with an overall AAD of 4.0%. (C) 2010 Taiwan Institute of Chemical Engineers. Published by Elsevier B.V. All rights reserved.
UT WOS:000286847500011
SN 1876-1070
doi 10.1016/j.jtice.2010.04.007

Publication type J
Title Health in Southeast Asia 2 Maternal, neonatal, and child health in
southeast Asia: towards greater regional collaboration
Author/s Acuin, CS Khor, GL Liabsuetrakul, T Achadi, EL Htay, TT Firestone, R Bhutta, ZA
Journal source LANCET
Vol 377
Issue 9764
Start page 516
End page 525
Publication year 2011
Times cited 0
Abstract Although maternal and child mortality are on the decline in southeast
Asia, there are still major disparities, and greater equity is key to
achieve the Millennium Development Goals. We used comparable
cross-national data sources to document mortality trends from 1990 to
2008 and to assess major causes of maternal and child deaths. We
present inequalities in intervention coverage by two common measures of
wealth quintiles and rural or urban status. Case studies of reduction
in mortality in Thailand and Indonesia indicate the varying extents of
success and point to some factors that accelerate progress. We
developed a Lives Saved Tool analysis for the region and for country
subgroups to estimate deaths averted by cause and intervention. We
identified three major patterns of maternal and child mortality
reduction: early, rapid downward trends (Brunei, Singapore, Malaysia,
and Thailand); initially high declines (sustained by Vietnam but
faltering in the Philippines and Indonesia); and high initial rates
with a downward trend (Laos, Cambodia, and Myanmar). Economic
development seems to provide an important context that should be
coupled with broader health-system interventions. Increasing coverage
and consideration of the health-system context is needed, and regional
support from the Association of Southeast Asian Nations can provide
increased policy support to achieve maternal, neonatal, and child
health goals.
UT WOS:000287381800033
SN 0140-6736
doi 10.1016/S0140-6736(10)62049-1

Publication type J
Title Stronger guidance needed on lifelong care for chronic diseases
Author/s Bermejo, RA Prashant, NS Sharma, SK
Journal source LANCET
Vol 377
Issue 9764
Start page 463
End page 463
Publication year 2011
Times cited 0
UT WOS:000287381800017
SN 0140-6736

Publication type J
Title Growth Response of Direct-Seeded Rice to Oxadiazon and
Bispyribac-Sodium in Aerobic and Saturated Soils
Author/s Chauhan, BS Johnson, DE
Journal source WEED SCIENCE
Vol 59
Issue 1
Start page 119
End page 122
Publication year 2011
Times cited 0
Abstract Studies were conducted to determine the growth responses of rice to PRE
application of oxadiazon and POST application of bispyribac-sodium.
Oxadiazon at 1.0 and 1.5 kg ha(-1) and bispyribac-sodium at 0.030 and
0.045 kg ha(-1) were applied to four rice varieties (‘IR64’, ‘IR72’,
‘RC09’, and ‘RC18’), which were grown in saturated and aerobic (30% of
saturation) soils. Control treatments, where no herbicides were
applied, were also included in the study. Shoot and root biomass, and
height of rice plants were measured 14 d after application. Phytotoxic
effects for both herbicides, including reduced shoot and root biomass,
were consistent in all varieties. Rice phytotoxicity symptoms were
greater when herbicides were applied to saturated than to aerobic
soils. Oxadiazon at 1.0 kg ha(-1) reduced rice shoot biomass by 22 to
36% in aerobic condition, and 43 to 56% in saturated condition when
compared with the control. Bispyribac-sodium reduced rice shoot biomass
by 9 to 17% at 0.030 kg ha(-1) in aerobic soil and 23 to 37% in
saturated soil. The results of this study suggest that soil water
content is an important factor influencing herbicide phytotoxicity in
rice, and its influence warrants further research to improve
understanding of physiology of phytotoxicity to minimize the effects of
these herbicides on crop production.
UT WOS:000286716700018
SN 0043-1745
doi 10.1614/WS-D-10-00075.1

Publication type J
Title Exhaustive measurement of food items in the home using a universal
product code scanner
Author/s Stevens, J Bryant, M Wang, LL Borja, J Bentley, ME
Vol 14
Issue 2
Start page 314
End page 318
Publication year 2011
Times cited 0
Abstract Objective: We aimed to develop, test and describe the Exhaustive Home
Food Inventory (EHFI), which measures foods in the home using scanning
of the universal product code (UPC) and EHFI software to link codes to
food identities and energy values.
Design: Observational design with up to three repeated measures in each
household yielded a total of 218 inventories.
Setting: Eighty private households in North Carolina.
Subjects: Low-income African-American women with an infant between the
ages of 12 and 18 months. Recruitment rate was 71%.
Results: Approximately 12 200 different food items were successfully
recorded using the EHFI method. The average number of food items within
a household was 147. The time required for the first measurement in a
home declined from 157 to 136 min (P<0.05) for the first third compared
to the last third of homes measured. In the sixty-four households in
which three assessments were performed, the time required decreased
from 145 to 97 min as did the time per item from 1.10 to 0.73 min.
Conclusions: It is feasible to record all foods and drinks in the home
using UPC scanning. Further development and enhancement of databases
linking UPC to food identification, nutrients and other information are
UT WOS:000287824100016
SN 1368-9800
doi 10.1017/S1368980010001837

Publication type J
Title Growth and survival of grouper Epinephelus coioides (Hamilton) larvae
fed free-living nematode Panagrellus redivivus at first feeding
Author/s Reyes, OS Duray, MN Santiago, CB Ricci, M
Vol 19
Issue 1
Start page 155
End page 164
Publication year 2011
Times cited 0
Abstract The free-living nematode, Panagrellus redivivus, was tested as live
food for grouper Epinephelus coioides larvae during the first feeding
stage. A series of experiments were conducted to determine the
acceptability of the free-living nematodes in grouper larvae at first
feeding, the optimum nematode density and the response of the larvae to
nutritionally enriched nematode. All experiments were conducted in
200-L conical tanks filled with 150-L filtered seawater and stocked at
15 larvae L-1. Duration of feeding experiments was up to day 21
(experiment 1) and 14 days (experiment 2 and 3). Brachionus plicatilis
and Artemia (experiment 1) and Brachionus plicatilis alone (experiment
2 & 3) was used as the control treatment. Observations indicated that
the grouper larvae readily fed on free-living nematodes as early as 3
days posthatching, the start of exogenous feeding. Optimum feeding
density for the larvae was 75 nematodes ml(-1). The enrichment of cod
liver oil or sunflower oil influenced the total lipids and n-3 highly
unsaturated fatty acids of P. redivivus, which in turn influenced those
of the grouper larvae, however, growth and survival of the larvae were
not affected (P > 0.05). The results from this investigation showed
that the nematode, P. redivivus, can be used as first live food for
grouper larvae from the onset of exogenous feeding until they could
feed on Artemia nauplii.
UT WOS:000286200300014
SN 0967-6120
doi 10.1007/s10499-010-9349-0

Publication type J
Title ‘Physical activity measurement instruments for children with cerebral
palsy: a systematic review’ Reply
Author/s Capio, CM Sit, CHP Abernethy, B Rotor, ER
Vol 53
Issue 2
Start page 192
End page 192
Publication year 2011
Times cited 0
UT WOS:000286329200024
SN 0012-1622
doi 10.1111/j.1469-8749.2010.03873.x

Publication type J
Title Mid-Holocene palaeoceanography of the northern South China Sea using
coupled fossil-modern coral and atmosphere-ocean GCM model
Author/s Yokoyama, Y Suzuki, A Siringan, F Maeda, Y Abe-Ouchi, A Ohgaito, R Kawahata, H Matsuzaki, H
Vol 38
Publication year 2011
Times cited 0
Abstract High-resolution records of past environments of the South China Sea
(SCS) could provide important information to better understand the
mechanisms of El Nino Southern Oscillation (ENSO) and East Asian
monsoon evolution since SCS is located between Pacific Ocean and
Eurasian continent. SCS plays a key role as the moisture source area of
monsoon precipitation that affects the terrestrial climate of Asia.
Fossil and modern corals were obtained from South China Sea (SCS) to
study changes in oceanographic conditions when the northern hemisphere
experienced perihelion during the early to mid-Holocene and thermal
contrast between SCS and the Asian continent was larger. The fossil
coral is 6600 years old and XRD and SEM investigations confirmed
pristine nature of this sample. Oxygen isotope measurement of modern
coral yielded an average value of ca. -6 parts per thousand, whereas
the fossil coral showed ca. -5.5 parts per thousand. Given that
previously reported alkenone SST thermometry and foraminiferal SST
reconstruction indicate little changes in SST (<0.5 degrees C)
throughout the Holocene in SCS, we consider the possibility of changes
in delta O-18 of seawater to be due to local sea surface salinity
(SSS). Coral data from the present study (6600 years old coral) as well
as previously published record (4400 years old) showed higher SSS
during the mid-Holocene. Coral data were then compared with the coupled
Ocean-Atmosphere GCM (MIROC3.2). Higher SSS during the mid-Holocene
time was also seen in AOGCM experiments. We observed northward shift of
inter tropical convergent zone (ITCZ) in the experiments that produced
increased precipitation on the Asian continent. The cause of increase
in salinity was, therefore, due to less precipitation in SCS and
increased continental precipitation inland of Asia. Citation: Yokoyama,
Y., A. Suzuki, F. Siringan, Y. Maeda, A. Abe-Ouchi, R. Ohgaito, H.
Kawahata, and H. Matsuzaki (2011), Mid-Holocene palaeoceanography of
the northern South China Sea using coupled fossil-modern coral and
atmosphere-ocean GCM model, Geophys. Res. Lett., 38, L00F03, doi:
UT WOS:000286324100001
SN 0094-8276
doi 10.1029/2010GL044231

Publication type J
Title Overcoming Multidrug Resistance of Breast Cancer Cells by the Micellar
Doxorubicin Nanoparticles of mPEG-PCL-Graft-Cellulose
Author/s Chen, CH Cuong, NV Chen, YT So, RC Liau, I Hsieh, MF
Vol 11
Issue 1
Start page 53
End page 60
Publication year 2011
Times cited 0
Abstract The amphiphilic block copolymer methoxy-poly(ethylene
glycol)-poly(epsilon-caprolactone) (mPEG-PCL) was grafted to
2-hydroxyethyl cellulose (HEC) to produce nano-sized micellar
nanoparticles. The nanoparticles were loaded with anti-tumor drug,
doxorubicin (DOX) and the size of the DOX-loaded nanoparticles were
determined by dynamic light scattering (DLS) in aqueous solution to be
from 197.4 to 230 nm. The nanoparticles subjected to co-culture with
macrophage cells showed that these nanoparticles used as drug carrier
are not recognized as foreign bodies. Overexpression of P-glycoprotein
(P-gp) is an important factor in the development of multidrug
resistance (MDR) in many cancer cells. In this study, Western blot and
Rhodamine 123 were used to monitor the relative P-glycoprotein
expression in human breast cancer cell lines MCF-7/WT and MCF-7/ADR.
The endocytosis of the DOX-loaded nanoparticles by breast cancer cells
is more efficient observed under a confocal laser scanning microscopy
(CLSM) and a flow cytometry in MCF7/ADR cells, compared to the
diffusion of the free drug into the cytoplasm of cells. Based on these
findings, we concluded that the nanoparticles made from
mPEG-PCL-g-cellulose were effective in overcoming P-gp efflux in MDR
breast cancer cells.
UT WOS:000286344400005
SN 1533-4880
doi 10.1166/jnn.2011.3102

Publication type J
Title Drought Resistance Improvement in Rice: An Integrated Genetic and
Resource Management Strategy
Author/s Serraj, R McNally, KL Slamet-Loedin, I Kohli, A Haefele, SM Atlin, G Kumar, A
Vol 14
Issue 1
Start page 1
End page 14
Publication year 2011
Times cited 0
Abstract Drought is the major constraint to rice production in rainfed areas
across Asia and sub-Saharan Africa. In the context of current and
predicted water scarcity, increasing irrigation is generally not a
viable option for alleviating drought problems in rainfed rice-growing
systems. It is therefore critical that genetic management strategies
for drought focus on maximum extraction of available soil moisture and
its efficient use in crop establishment and growth to maximize biomass
and yield. Extensive genetic variation for drought resistance exists in
rice germplasm. However, the current challenge is to decipher the
complexities of drought resistance in rice and exploit all available
genetic resources to produce rice varieties combining drought
adaptation with high yield potential, quality, and resistance to biotic
stresses. The strategy described here aims at developing a pipeline for
elite breeding lines and hybrids that can be integrated with efficient
management practices and delivered to rice farmers. This involves the
development of high-throughput, high-precision phenotyping systems to
allow genes for yield components under stress to be efficiently mapped
and their effects assessed on a range of drought-related traits, and
then moving the most promising genes into widely grown rice
mega-varieties, while scaling up gene detection and delivery for use in
marker-aided breeding.
UT WOS:000286645000001
SN 1343-943X

Publication type J
Title A PCR-based marker for a locus conferring aroma in vegetable soybean
(Glycine max L.)
Author/s Arikit, S Yoshihashi, T Wanchana, S Tanya, P Juwattanasomran, R Srinives, P Vanavichit, A
Vol 122
Issue 2
Start page 311
End page 316
Publication year 2011
Times cited 0
Abstract Vegetable soybean (Glycine max L.) is an important economic and
nutritious crop in South and Southeast Asian countries and is
increasingly grown in the Western Hemisphere. Aromatic vegetable
soybean is a special group of soybean varieties that produce young pods
containing a sweet aroma, which is produced mainly by the volatile
compound 2-acetyl-1-pyrroline (2AP). Due to the aroma, the aromatic
vegetable soybean commands higher market prices and gains wider
acceptance from unfamiliar consumers. We have previously reported that
the GmAMADH2 gene encodes an AMADH that regulates aroma (2AP)
biosynthesis in soybeans (Arikit et al. 2010). A sequence variation
involving a 2-bp deletion in exon 10 was found in this gene in all
investigated aromatic varieties. In this study, a codominant PCR-based
marker for the aroma trait in soybeans was designed based on the 2-bp
deletion in GmAMADH2. The marker was verified in five aromatic and five
non-aromatic varieties as well as in F-2 soybean population segregating
for aroma. The aromatic genotype with the 2-bp deletion was completely
associated with the five aromatic soybean varieties as well as the
aromatic progeny of the F-2 population with seeds containing 2AP.
Similarly, the non-aromatic genotype was associated with the five
non-aromatic varieties and non-aromatic progeny. The perfect
co-segregation of the marker genotypes and aroma phenotypes confirmed
that the marker could be efficiently used for molecular breeding of
soybeans for aroma.
UT WOS:000286198000006
SN 0040-5752
doi 10.1007/s00122-010-1446-y

Publication type J
Title Dissecting quantitative resistance against blast disease using
heterogeneous inbred family lines in rice
Author/s Liu, Y Zhu, X Zhang, SH Bernardo, M Edwards, J Galbraith, DW Leach, J Zhang, GS Liu, B Leung, H
Vol 122
Issue 2
Start page 341
End page 353
Publication year 2011
Times cited 0
Abstract SHZ-2 is an indica rice cultivar that exhibits broad-spectrum
resistance to rice blast; it is widely used as a resistance donor in
breeding programs. To dissect the QTL responsible for broad-spectrum
blast resistance, we crossed SHZ-2 to TXZ-13, a blast susceptible
indica variety, to produce 244 BC4F3 lines. These lines were evaluated
for blast resistance in greenhouse and field conditions. Chromosomal
introgressions from SHZ-2 into the TXZ-13 genome were identified using
a single feature polymorphism microarray, SSR markers and gene-specific
primers. Segregation analysis of the BC4F3 population indicated that
three regions on chromosomes 2, 6, and 9, designated as qBR2.1, qBR6.1,
and qBR9.1, respectively, was associated with blast resistance and
contributed 16.2, 14.9, and 22.3%, respectively, to the phenotypic
variance of diseased leaf area (DLA). We further narrowed the three QTL
regions using pairs of sister lines extracted from heterogeneous inbred
families (HIF). Pairwise comparison of these lines enabled the
determination of the relative contributions of individual QTL. The
qBR9.1 conferred strong resistance, whereas qBR2.1 or qBR6.1
individually did not reduce disease under field conditions. However,
when qBR2.1 and qBR6.1 were combined, they reduced disease by 19.5%,
suggesting that small effect QTLs contribute to reduction of epidemics.
The qBR6.1 and qBR9.1 regions contain nucleotide-binding sites and
leucine rich repeats (NBS-LRR) sequences, whereas the qBR2.1 did not.
In the qBR6.1 region, the patterns of expression of adjacent NBS-LRR
genes were consistent in backcross generations and correlated with
blast resistance, supporting the hypothesis that multiple resistance
genes within a QTL region can contribute to non-race-specific
quantitative resistance.
UT WOS:000286198000009
SN 0040-5752
doi 10.1007/s00122-010-1450-2

Publication type J
Title White spot syndrome virus (WSSV) risk factors associated with shrimp
farming practices in polyculture and monoculture farms in the
Author/s Tendencia, EA Bosma, RH Verreth, JAJ
Journal source AQUACULTURE
Vol 311
Issue 1-4
Start page 87
End page 93
Publication year 2011
Times cited 0
Abstract White spot sydrome virus (WSSV) is one of the most important viral
disease of shrimp. Several studies to control the disease have been
done. Tank experiments identified WSSV risk factors related to the
physico chemical properties of the water. A few studies reported pond
level WSSV risk factors. This study identifies the risk factors
associated with essentially two different farming systems: polyculture
and semi-intensive monoculture of Penaeus monodon. Data were gathered
from a total of 174 shrimp farmers in eight provinces of the
Philippines using a structured questionnaire. Forty-seven variables
related to pond history and site description, period of culture, pond
preparation techniques, water management, culture methods, feed and
other inputs, and biosecurity measures were investigated. In the
analysis for combined monoculture and polyculture farms, feeding live
molluscs was identified as important WSSV risk factors. In addition to
feeding live molluscs, sharing of water source with other farms, having
the same receiving and water source, larger pond size, and higher
stocking density were identified as important WSSV risk factors in
monoculture farms. Climate, i.e. stocking during the cold months and
sludge removal and its deposition on the dikes were identified as WSSV
risk factors in polyculture farms. Protective factors, listed in
decreasing significance, were feeding with planktons and high mangrove
to pond area ratio, both observed in the dataset with both monoculture
and polyculture farms, while only the latter was observed in the
dataset for monoculture farms only. No protective factor was observed
in the dataset for polyculture farms.
This study confirmed the negative effect of sharing water source with
other farms and identified several new factors influencing WSSV
infection such as feeding live molluscs increases the risk, while
feeding with planktons and high mangrove to pond area ratio reduce the
risk. (C) 2010 Elsevier B.V. All rights reserved.
UT WOS:000287432600013
SN 0044-8486
doi 10.1016/j.aquaculture.2010.11.039

Publication type J
Title Root-Specific Transcript Profiling of Contrasting Rice Genotypes in
Response to Salinity Stress
Author/s Cotsaftis, O Plett, D Johnson, AAT Walia, H Wilson, C Ismail, AM Close, TJ Tester, M Baumann, U
Journal source MOLECULAR PLANT
Vol 4
Issue 1
Start page 25
End page 41
Publication year 2011
Times cited 0
Abstract Elevated salinity imposes osmotic and ion toxicity stresses on living
cells and requires a multitude of responses in order to enable plant
survival. Building on earlier work profiling transcript levels in rice
(Oryza sativa) shoots of FL478, a salt-tolerant indica recombinant
inbred line, and IR29, a salt-sensitive cultivar, transcript levels
were compared in roots of these two accessions as well as in the roots
of two additional salt-tolerant indica genotypes, the landrace Pokkali
and the recombinant inbred line IR63731. The aim of this study was to
compare transcripts in the sensitive and the tolerant lines in order to
identify genes likely to be involved in plant salinity tolerance,
rather than in responses to salinity per se. Transcript profiles of
several gene families with known links to salinity tolerance are
described (e.g. HKTs, NHXs). The putative function of a set of genes
identified through their salt responsiveness, transcript levels, and/or
chromosomal location (i.e. underneath QTLs for salinity tolerance) is
also discussed. Finally, the parental origin of the Saltol region in
FL478 is further investigated. Overall, the dataset presented appears
to be robust and it seems likely that this system could provide a
reliable strategy for the discovery of novel genes involved in salinity
UT WOS:000286674900003
SN 1674-2052
doi 10.1093/mp/ssq056

Publication type J
Title Reversible and Irreversible Drought-Induced Changes in the Anther
Proteome of Rice (Oryza sativa L.) Genotypes IR64 and Moroberekan
Author/s Liu, JX Bennett, J
Journal source MOLECULAR PLANT
Vol 4
Issue 1
Start page 59
End page 69
Publication year 2011
Times cited 3
Abstract Crop yield is most sensitive to water deficit during the reproductive
stage. For rice, the most sensitive yield component is spikelet
fertility and the most sensitive stage is immediately before heading.
Here, we examined the effect of drought on the anther proteome of two
rice genotypes: Moroberekan and IR64. Water was withheld for 3 d before
heading (3DBH) in well watered controls for 5 d until the flag leaf
relative water content (RWC) had declined to 45-50%. Plants were then
re-watered and heading occurred 2-3 d later, representing a delay of
4-5 d relative to controls. The anther proteins were separated at 3
DBH, at the end of the stress period, and at heading in
stressed/re-watered plants and controls by two-dimensional (2-D) gel
electrophoresis, and 93 protein spots were affected reproducibly in
abundance by drought during the experiment across two rice genotypes.
After drought stress, upon re-watering, expressions of 24 protein spots
were irreversible in both genotypes, 60 protein spots were irreversible
in IR64 but reversible in Moroberekan, only nine protein spots were
irreversible in Moroberekan while reversible in IR64. Among them, there
were 14 newly drought-induced protein spots in IR64; none of them was
reversible on re-watering. However, there were 13 newly drought-induced
protein spots in Moroberekan, 10 of them were reversible on
re-watering, including six drought-induced protein spots that were not
reversed in IR64. Taken together, our proteomics data reveal that
drought-tolerant genotype Moroberekan possessed better recovery
capability following drought and re-watering at the anther proteome
level than the drought-sensitive genotype IR64. The disruptions of
drought to rice anther development and pollen cell functions are also
discussed in the paper.
UT WOS:000286674900005
SN 1674-2052
doi 10.1093/mp/ssq039

Publication type J
Title Detection of koi herpesvirus (KHV) from koi (Cyprinus carpio koi)
broodstock in South Korea
Author/s Gomez, DK Joh, SJ Jang, H Shin, SP Choresca, CH Han, JE Kim, JH Jun, JW Park, SC
Journal source AQUACULTURE
Vol 311
Issue 1-4
Start page 42
End page 47
Publication year 2011
Times cited 0
Abstract The presence of koi herpesvirus (KHV) was confirmed in three ornamental
koi broodstocks for breeding purposes. The broodstocks showed poor
appetite, lethargy, abnormal swimming behavior with gasping movements
in shallow water and increased mucus secretion. Histopathologically,
the gill showed diffuse necrosis of the branchial epithelial cells and
diffuse lymphocytic-monocytic interstitial nephritis with necrosis of
the tubular epithelial cells predominantly found in these three
broodstocks. The presence of viral intranuclear inclusion bodies were
also observed. KHV was not isolated using KF-1 cell line but PCR
positive results at 484 bp DNA product was confirmed in all organs of
the fish and quatification of KHV genomic DNA using real-time Taqman
PCR in all organs ranged from 1.32 x 10(-9) to 1.39 x 10(-9) copy
numbers. The analysis of sequencing data of 484 bp fragments of KHV DNA
of three Korean isolates revealed 100% identities with each other and
closely related (98 to 99%) to the known CyHV-3 type of KHV. This
report confirmed the presence of KHV infection in one koi commercial
farm in South Korea using pathological and molecular methods. (C) 2010
Elsevier By. All rights reserved.
UT WOS:000287432600006
SN 0044-8486
doi 10.1016/j.aquaculture.2010.11.021

Publication type J
Title Molecular analysis of new isolates of Tomato leaf curl Philippines
virus and an associated betasatellite occurring in the Philippines
Author/s Sharma, P Matsuda, N Bajet, NB Ikegami, M
Vol 156
Issue 2
Start page 305
End page 312
Publication year 2011
Times cited 1
Abstract Three new begomovirus isolates and one betasatellite were obtained from
a tomato plant exhibiting leaf curl symptom in Laguna, the Philippines.
Typical begomovirus DNA components representing the three isolates
(PH01, PH02 and PH03) were cloned, and their full-length sequences were
determined to be 2754 to 2746 nucleotides. The genome organizations of
these isolates were similar to those of other Old World monopartite
begomoviruses. The sequence data indicated that PH01 and PH02 were
variants of strain B of the species Tomato leaf curl Philippines virus,
while PH03 was a variant of strain A of the species Tomato leaf curl
Philippines virus. These isolates were designated ToLCPV-B[PH:Lag1:06],
ToLCPV-B[PH:Lag2:06], and ToLCPV-A[PH:Lag3:06], respectively.
Phylogenetic analysis revealed that the present isolates form a
separate monophyletic cluster with indigenous begomoviruses reported
earlier in the Philippines. A betasatellite isolated from same sample
belongs to the betasatellite species Tomato leaf curl Philippines
betasatellite and designated Tomato leaf curl Philippines
betasatellite-[Philippines:Laguna1:2006], ToLCPHB-[PH:Lag1:06]. When
co-inoculated with this betasatellite, tomato leaf curl Philippines
virus induced severe symptoms in N. benthamiana and Solanum
lycopersicum plants. Using a PVX-mediated transient assay, we found
that the C4 and C2 proteins of tomato leaf curl Philippines virus and
the beta C1 protein of ToLCPHB-[PH:Lag1:06] function as a suppressor of
RNA silencing.
UT WOS:000286828500012
SN 0304-8608
doi 10.1007/s00705-010-0837-3

Publication type J
Title Susceptibility of hatchery-reared snubnose pompano Trachinotus blochii
to natural betanodavirus infection and their immune responses to the
inactivated causative virus
Author/s Pakingking, R Mori, KI Bautista, NB de Jesus-Ayson, EG Reyes, O
Journal source AQUACULTURE
Vol 311
Issue 1-4
Start page 80
End page 86
Publication year 2011
Times cited 0
Abstract Mass mortality of snubnose pompano Trachinotus blochii fry exhibiting
dark coloration, anorexia, and abnormal swimming behavior was recently
documented at the hatchery of the Aquaculture Department of the
Southeast Asian Fisheries Development Center, Philippines. Samples of
brain tissues were collected from affected fish and processed for
RT-PCR amplification and virus isolation in cell culture. Infected E-11
cells exhibited cytopathic effect characteristic of betanodavirus.
Histopathology of moribund fish showed pronounced vacuolations in the
brain, spinal cord, and retina. An RT-PCR product of approximately 430
bp was amplified from the culture supernatant of betanodavirus-infected
E-11 cells and sequenced. Sequencing of the T4 region of the coat
protein gene (RNA 2) revealed clustering of the isolated virus within
the red-spotted grouper nervous necrosis virus type. The pathogenicity
of the isolated betanodavirus in healthy pompano juveniles and fry was
determined via intramuscular injection and immersion challenges,
respectively. Higher mortality rates were obtained in challenged fish
compared with the controls. An inactivated vaccine was subsequently
prepared by treating the clarified betanodavirus with formalin. Pompano
juveniles intraperitoneally injected with the inactivated vaccine
exhibited neutralizing antibodies from days 15 (mean titer 1:240) to
125 (1:560) with the highest titer noted at day 64(1:2240)
post-vaccination. Additionally, pompano fry bath-vaccinated and
consequently bath-challenged with betanodavirus at day 35
post-vaccination showed higher survival rate compared with the control,
indicating the potential of the inactivated betanodavirus vaccine
against VNN in pompano fry and juveniles. (C) 2010 Elsevier B.V. All
rights reserved.
UT WOS:000287432600012
SN 0044-8486
doi 10.1016/j.aquaculture.2010.11.035

Publication type J
Title High-precision frequency measurement of the 423-nm Ca I line
Author/s Salumbides, EJ Maslinskas, V Dildar, IM Wolf, AL van Duijn, EJ Eikema, KSE Ubachs, W
Journal source PHYSICAL REVIEW A
Vol 83
Issue 1
Publication year 2011
Times cited 0
Abstract We have performed an accurate frequency calibration of the 4s(2) S-1(0)
-> 4s4p P-1(1) principal resonance line of the neutral calcium atom at
423 nm. Doppler-free cw excitation on a Ca atomic beam was performed by
utilizing a Sagnac geometry in the alignment of the excitation beams.
From frequency calibrations against a frequency comb, stabilized to a
global positioning system (GPS) disciplined Rb standard, the transition
frequency is determined at 709 078 373.01(35) MHz for the main Ca-40
isotope. Slightly lower accuracies are obtained for the transition
frequencies of the less abundant isotopes. The achieved fractional
uncertainty of 5 x 10(-10) exceeds the requirements for including this
transition in investigations that aim to probe a possible variation in
the fine-structure constant a on cosmological time scales.
UT WOS:000286732900004
SN 1050-2947
doi 10.1103/PhysRevA.83.012502

Publication type J
Title A Clean Air Scorecard for Asian Cities
Author/s Patdu, MK Ajero, MA
CT Joint Conference of
CY AUG 28-SEP 01, 2010
Journal source EPIDEMIOLOGY
Vol 22
Issue 1
Start page S150
End page S150
Publication year 2011
Times cited 0
UT WOS:000285400800440
SN 1044-3983

Publication type J
Title Identification of rhizome-specific genes by genome-wide differential
expression Analysis in Oryza longistaminata
Author/s Hu, FY Wang, D Zhao, XQ Zhang, T Sun, HX Zhu, LH Zhang, F Li, LJ Li, QO Tao, DY Fu, BY Li, ZK
Journal source BMC PLANT BIOLOGY
Vol 11
Publication year 2011
Times cited 0
Abstract Background: Rhizomatousness is a key component of perenniality of many
grasses that contribute to competitiveness and invasiveness of many
noxious grass weeds, but can potentially be used to develop perennial
cereal crops for sustainable farmers in hilly areas of tropical Asia.
Oryza longistaminata, a perennial wild rice with strong rhizomes, has
been used as the model species for genetic and molecular dissection of
rhizome development and in breeding efforts to transfer rhizome-related
traits into annual rice species. In this study, an effort was taken to
get insights into the genes and molecular mechanisms underlying the
rhizomatous trait in O. longistaminata by comparative analysis of the
genome wide tissue specific gene expression patterns of five different
tissues of O. longistaminata using the Affymetrix GeneChip Rice Genome
Results: A total of 2,566 tissue-specific genes were identified in five
different tissues of O. longistaminata, including 58 and 61 unique
genes that were specifically expressed in the rhizome tips (RT) and
internodes (RI), respectively. In addition, 162 genes were up-regulated
and 261 genes were down-regulated in RT compared to the shoot tips. Six
distinct cis-regulatory elements (CGACG, GCCGCC, GAGAC, AACGG, CATGCA,
and TAAAG) were found to be significantly more abundant in the promoter
regions of genes differentially expressed in RT than in the promoter
regions of genes uniformly expressed in all other tissues. Many of the
RT and/or RI specifically or differentially expressed genes were
located in the QTL regions associated with rhizome expression, rhizome
abundance and rhizome growth-related traits in O. longistaminata and
thus are good candidate genes for these QTLs.
Conclusion: The initiation and development of the rhizomatous trait in
O. longistaminata are controlled by very complex gene networks
involving several plant hormones and regulatory genes, different
members of gene families showing tissue specificity and their regulated
pathways. Auxin/IAA appears to act as a negative regulator in rhizome
development, while GA acts as the activator in rhizome development.
Co-localization of the genes specifically expressed in rhizome tips and
rhizome internodes with the QTLs for rhizome traits identified a large
set of candidate genes for rhizome initiation and development in rice
for further confirmation.
UT WOS:000287208300001
SN 1471-2229
doi 10.1186/1471-2229-11-18

Publication type J
Title Synthetic, spectroscopic, and structural studies on organoimido
molybdenum, tungsten, and rhenium phthalocyanines
Author/s Darwish, W Seikel, E Harms, K Burghaus, O xSundermeyer, J
Vol 40
Issue 5
Start page 1183
End page 1188
Publication year 2011
Times cited 0
Abstract Unprecedented imido phthalocyaninato complexes of pentavalent
refractory metals [PcM(NR)Cl] (M = Mo, W, Re; R = tBu: 1, 3, 6, Mes: 2,
4, 7 or Ts: 5) have been synthesized by reductive cyclotetramerization
of phthalonitrile in the presence of appropriate bis(imido) complexes
of Mo, W and Re as templates. While d(1) Mo(V) and W(V) species 1-5
show distinctive EPR spectra corresponding to metal centered radicals
with hyperfine coupling of two magnetically non-equivalent nitrogen
atoms (4 equatorial and 1 axial N), corresponding d(2) Re(V) compounds
6 and 7 are diamagnetic. [PcMo(NtBu)Cl] 1 crystallizes from
1-chloronaphthalene in the tetragonal space group P4/n. The molecular
structure reveals, that the metal center is located above the plane of
the equatorial N4 and displaced towards the axial pi-donor ligand. Due
to the thermodynamic trans effect the Mo Cl bond trans to the imido
group is elongated to about 2.600(2) angstrom.
UT WOS:000286390300026
SN 1477-9226
doi 10.1039/c0dt01166e

Publication type J
Title Testing absolute and percentage thresholds in the identification of key
biodiversity areas
Author/s Edgar, GJ Brooks, TM
Vol 14
Issue 1
Start page 12
End page 13
Publication year 2011
Times cited 1
UT WOS:000287359800002
SN 1367-9430
doi 10.1111/j.1469-1795.2011.00438.x

Publication type J
Title Parasitoids of Asian rice planthopper (Hemiptera: Delphacidae) pests
and prospects for enhancing biological control by ecological engineering
Author/s Gurr, GM Liu, J Read, DMY Catindig, JLA Cheng, J ALan, LP Heong, KL
Vol 158
Issue 2
Start page 149
End page 176
Publication year 2011
Times cited 0
Abstract The brown planthopper (BPH) Nilaparvata lugens, whitebacked planthopper
(WBPH) Sogatella furcifera and smaller BPH Laodelphax striatellus
increasingly exhibit resistance to insecticides and adaptation to
resistant varieties, so they threaten food security. This review draws
together, for the first time, information on the parasitoids of
planthopper pests of rice from the non-English literature published in
Asia. This is integrated with the English language literature to
provide a comprehensive analysis. Planthopper pests of rice are
attacked by a large range of parasitoids from Strepsiptera, Diptera
and, especially, Hymenoptera. Levels of field parasitism vary widely
between parasitoid species and locations. For many taxa, especially
within Mymaridae, there is evidence that non-crop habitats are
important as overwintering habitat in which alternative hosts are
available. These source habitats may promote early season parasitism of
pest Hemiptera in rice crops, and their movement into crops could be
manipulated with applications of herbivore-induced plant volatiles.
Non-crop plants can also provide nectar to improve parasitoid longevity
and fecundity. Despite evidence for the importance of environmental
factors affecting parasitoids of rice pests, the use of habitat
manipulation to enhance biological control in the world’s most
important crop is surprisingly underrepresented in the literature.
Current research in China, Vietnam and Thailand on ecological
engineering, carefully selected vegetation diversity introduced without
disrupting profitable farming, is briefly reported. Although the most
important pest, BPH (N. lugens), is a migratory species, maintaining
local communities of parasitoids and other natural enemies offers scope
to prevent even r-selected pests from reaching damaging population
UT WOS:000287191900001
SN 0003-4746
doi 10.1111/j.1744-7348.2010.00455.x

Publication type J
Title Fuzzy optimization of topologically constrained eco-industrial resource
conservation networks with incomplete information
Author/s Aviso, KB Tan, RR Culaba, AB Foo, DCY Hallale, N
Vol 43
Issue 3
Start page 257
End page 279
Publication year 2011
Times cited 2
Abstract It is possible to minimize industrial resource consumption by
establishing eco-industrial resource conservation networks (RCN)
between different plants. The establishment of these networks requires
the satisfaction of quality criteria for material properties deemed
significant by an industry. It also necessitates cooperation among the
different firms based on the satisfaction of individual cost or
resource consumption goals. Furthermore, there may be varying degrees
of incomplete information regarding the process data of the
participating plants. Eco-industrial RCNs may also be topologically
constrained with respect to the number of links connecting different
plants. These design aspects are incorporated in the optimization model
through fuzzy mixed integer linear programming (FMILP) or fuzzy mixed
integer non-linear programming (FMINLP). Case studies from literature
involving water integration and hydrogen recovery are used to
illustrate the methodology. The model is able to identify the
topologically constrained network that achieves the highest level of
overall satisfaction among participating plants.
UT WOS:000287206100002
SN 0305-215X
doi 10.1080/0305215X.2010.486031

Publication type J
Title Tropical Street Trees and Climate Uncertainty in Southeast Asia
Author/s Kjelgren, R Trisurat, Y Puangchit, L Baguinon, N Yok, PB
Journal source HORTSCIENCE
Vol 46
Issue 2
Start page 167
End page 172
Publication year 2011
Times cited 1
Abstract Urban trees are a critical quality of life element in rapidly growing
cities in tropical climates. Tropical trees are found in a wide variety
of habitats governed largely by the presence and duration of monsoonal
dry periods. Tropical cities can serve as a proxy for climate change
impacts of elevated carbon dioxide (CO2), urban heat island, and
drought-prone root zones on successful urban trees. Understanding the
native habitats of species successful as tropical urban trees can yield
insights into the potential climate impact on those habitats. Species
from equatorial and montane wet forests where drought stress is not a
limiting factor are not used as urban trees in cities with monsoonal
dry climates such as Bangkok and Bangalore. Absence of trees from a wet
habitat in tropical cities in monsoonal climates is consistent with
model and empirical studies suggesting wet evergreen species are
vulnerable to projected climates changes such as lower rainfall and
increased temperatures. However, monsoonal dry forest species appear to
have wider environmental tolerances and are successful urban trees in
cities with equatorial wet climates such as Singapore as well as cities
with monsoonal climates such as Bangkok and Bangalore. In cities with
monsoonal dry climates, deciduous tree species are more common than dry
evergreen species. Although dry deciduous species generally have better
floral displays, their prevalence may in part be the result of greater
tolerance of urban heat islands and drought in cities; this would be
consistent with modeled habitat gains at the expense of dry evergreen
species in native forest stands under projected higher temperatures
from climate change. Ecological models may also point to selection of
more heat- and drought-tolerant species for tropical cities under
projected climate change.
UT WOS:000287336000005
SN 0018-5345

Publication type J
Title What aspects of the health technology assessment process recommended by
international health technology assessment agencies received the most
attention in Poland in 2008?
Author/s Kolasa, K Dziomdziora, M Fajutrao, L
Vol 27
Issue 1
Start page 84
End page 94
Publication year 2011
Times cited 0
Abstract Objectives: The primary objective of this study was to determine the
extent to which international standards on transparency and quality are
met by the health technology assessment (HTA) process in Poland. A
secondary objective is to describe the outcomes of the HTA process and
their associated factors.
Methods: All published online HTA appraisal and meeting proceedings on
pharmaceutical products in 2008 were reviewed using a score card
developed from international checklists recommended by INAHTA and
Results: The sixty-nine reports reviewed showed that five of nine
transparency standards and six of eight quality standards were usually
met by the HTA reports. Areas for improvement for transparency include
inputs from external stakeholders, availability of English summaries,
conclusions, implications of results, and suggested program of action.
Areas of improvement for quality include appropriateness of target
population and comparator/s, sufficiency of evidence on efficacy and
safety, methodological rigor, economic model assumptions, and
adaptation to the Polish setting. A consideration of the ethical and
social consequences to the healthcare system must also be strengthened.
Conclusions: The study demonstrates that the incorporation and
implementation of the HTA appraisal process in Poland has been
successful. HTA appraisal reports in Poland have considered most of the
international standards of transparency and quality. Recommendations
for both HTA users and doers are forwarded for the improvement of the
HTA process in the Polish setting.
UT WOS:000287270100012
SN 0266-4623
doi 10.1017/S0266462310001236

Publication type J
Title Ternary diffusion coefficients of DEG and LiBr in aqueous glycol-salt
system (DEG + LiBr + H2O)
Author/s Peng, SW Soriano, AN Leron, RB Li, MH
Vol 42
Issue 2
Start page 233
End page 239
Publication year 2011
Times cited 0
Abstract The ternary diffusion coefficients of diethylene glycol (DEG) and LiBr
in aqueous glycol-salt solution containing DEC + LiBr + H2O were
measured using the Taylor dispersion method. Measurements were done for
temperatures of 303.15, 308.15, and 313.15 K The investigated ternaries
of the aqueous glycol-salt system contained total solute concentrations
of 10, 15, and 20 wt%. The ternary diffusion coefficients, i.e. main
diffusion coefficients (D-11 and D-22) and the cross-diffusion
coefficients (D-12 and D-21), were correlated to temperature and
concentration. A modified equation based on that proposed by Batchelor
(1983) for a mixture of hard spheres in a continuum solvent was used to
correlate the present diffusion coefficient data. Calculations yield
satisfactory results. (C) 2010 Taiwan Institute of Chemical Engineers.
Published by Elsevier B.V. All rights reserved.
UT WOS:000287228600007
SN 1876-1070
doi 10.1016/j.jtice.2010.07.015

Publication type J
Title Diffusion coefficients of aqueous ionic liquid solutions at infinite
dilution determined from electrolytic conductivity measurements
Author/s Soriano, AN Agapito, AM Lagumbay, LJLI Caparanga, AR Li, MH
Vol 42
Issue 2
Start page 258
End page 264
Publication year 2011
Times cited 0
Abstract In this work, the molar conductivities of aqueous solutions of the
ionic liquids abbreviated as [Bdmim][BE4], [Bdmim][PF6], [Bmim][Br],
and [Bmim][CI] are reported. Such data were determined from the
electrolytic conductivities of the systems, which were measured at
different concentrations (dilute region) and temperatures (from 303.15
to 323.15 K). From these data, the infinite dilution diffusion
coefficients of the ionic liquids and ionic diffusion coefficients were
estimated using the Nernst-Haskell equation. Another theoretical
equation, the Nernst-Einstein equation, was, likewise, used to
determine the hydrodynamic radii of the considered ions in this work.
(C) 2010 Taiwan Institute of Chemical Engineers. Published by Elsevier
B.V. All rights reserved.
UT WOS:000287228600011
SN 1876-1070
doi 10.1016/j.jtice.2010.06.003

Publication type J
Title DNA barcodes of Philippine accipitrids
Author/s Ong, PS Luczon, AU Quilang, JP Sumaya, AMT Ibanez, JC Salvador, DJ Fontanilla, IKC
Vol 11
Issue 2
Start page 245
End page 254
Publication year 2011
Times cited 0
Abstract DNA barcoding is a molecular method that rapidly identifies an
individual to a known taxon or its closest relative based on a 650-bp
fragment of the cytochrome c oxidase subunit I (COI). In this study,
DNA barcodes of members of the family Accipitridae, including Haliastur
indus (brahminy kite), Haliaeetus leucogaster (white-bellied sea
eagle), Ichthyophaga ichthyaetus (grey-headed fish eagle), Spilornis
holospilus (crested serpent-eagle), Spizaetus philippensis (Philippine
hawk-eagle), and Pithecophaga jefferyi (Philippine eagle), are reported
for the first time. All individuals sampled are kept at the Philippine
Eagle Center in Davao City, Philippines. Basic local alignment search
tool results demonstrated that the COI sequences for these species were
unique. The COI gene trees constructed using the maximum-likelihood and
neighbour-joining (NJ) methods supported the monophyly of the booted
eagles of the Aquilinae and the sea eagles of the Haliaeetinae but not
the kites of the Milvinae.
UT WOS:000287200200003
SN 1755-098X
doi 10.1111/j.1755-0998.2010.02928.x

Publication type J
Title A 13-nation population survey of upper gastrointestinal symptoms:
prevalence of symptoms and socioeconomic factors
Author/s Haag, S Andrews, JM Gapasin, J Gerken, G Keller, A Holtmann, GJ
Vol 33
Issue 6
Start page 722
End page 729
Publication year 2011
Times cited 0
Abstract P>Background
Previous data collected in separate studies using various different
survey instruments have suggested some variability in the prevalence of
symptoms between nations. However, there is a lack of studies which
assess and compare the prevalence of upper gastrointestinal symptoms
contemporaneously in various countries using a uniform, standardised
To determine the prevalence of upper gastrointestinal (UGI) symptoms in
13 European countries, and the association between socioeconomic
factors and symptoms using a standardised method.
A representative age- and gender-stratified sample of 23 163 subjects
(aged 18-69 years) was surveyed.
The prevalence of UGI symptoms was 38%. UGI symptoms were most
prevalent in Hungary [45%, 95% confidence interval (CI): 42.2-48.4] and
lowest in the Netherlands (24%, 95% CI: 21.0-26.2). UGI symptoms were
more prevalent in women (39%, 95% CI: 38.4-39.6) vs. men (37%, 95% CI:
36.4-37.6). Heartburn (24%, 95% CI: 23.4-24.6) and acidic reflux (14%,
95% CI: 13.6-14.4) were most common. With age, the prevalence of UGI
symptoms decreased (e.g. 18-29 years: 43%, 95% CI: 41.4-44.3 vs. 50-69
years: 33%, 95% CI: 32.3-34.4); in contrast, the frequency of symptom
episodes/year increased with age (e.g. 18-29 years: 11.3 episodes per
years, 95% CI: 10.5-12.1 vs. 50-69 years: 21.8, 95% CI: 20.7-22.9).
Socioeconomic status as measured by gross domestic product was
inversely associated with symptoms and in total, socioeconomic factors,
gender, body mass index, smoking habits and alcohol consumption
explained 83% of the variance of UGI symptoms.
There are marked differences in the country specific prevalence of
upper gastrointestinal complaints. Socioeconomic factors are closely
associated with the prevalence of upper gastrointestinal symptoms.
UT WOS:000287361000011
SN 0269-2813
doi 10.1111/j.1365-2036.2010.04564.x

Publication type J
Title Low temperature photoluminescence and Raman phonon modes of
Au-catalyzed MBE-grown GaAs-AlGaAs core-shell nanowires grown on a
pre-patterned Si (111) substrate
Author/s Bailon-Somintac, MF Ibanez, JJ Jaculbia, RB Loberternos, RA Defensor, MJ Salvador, AA Somintac, AS
Vol 314
Issue 1
Start page 268
End page 273
Publication year 2011
Times cited 0
Abstract We present the optical properties of MBE-grown GaAs-AlGaAs core-shell
nanowires (NWs) grown on anodized-aluminum-oxide (AAO) patterned-Si (1
1 1) substrate using photoluminescence and Raman scattering
spectroscopy. The GaAs NWs were grown via the vapor-liquid-solid method
with Au-nanoparticles as catalysts. Enhancement in emission of at least
an order of magnitude was observed from the GaAs-AlGaAs core-shell NWs
as compared to the bare GaAs NWs grown under similar conditions. which
is an indication of improved radiative efficiency. The improvement in
radiative efficiency is due to the passivating effect of the AlGaAs
shell. Variation in bandgap emission energy as a function of
temperature was analyzed using the semi-empirical Bose-Einstein model.
Results show that the free exciton energy of the GaAs core-shell agrees
well with the known emission energy of zinc blende (ZB) bulk GaAs.
Further analysis on the linear slope of the temperature dependence
curve of photoluminescence emission energy at low temperatures shows
that there is no difference between core-shell nanowires and bulk GaAs,
strongly indicating that the grown NWs are indeed predominantly ZB in
structure. The Raman modes show downshift and asymmetrical broadening,
which are characteristic features of NWs. The downshift is attributed
to lattice defects rather than the confinement or shape effect. (C)
2010 Elsevier B.V. All rights reserved.
UT WOS:000286853400049
SN 0022-0248
doi 10.1016/j.jcrysgro.2010.10.152

Publication type J
Title Southeast Asia: an emerging focus for global health
Author/s Acuin, J Firestone, R Htay, TT Khor, GL Thabrany, H Saphonn, V Wibulpolprasert, S
Journal source LANCET
Vol 377
Issue 9765
Start page 534
End page 535
Publication year 2011
Times cited 0
UT WOS:000287556700006
SN 0140-6736
doi 10.1016/S0140-6736(10)61426-2

Publication type J
Title Small mammal diversity along an elevational gradient in northern Luzon,
Author/s Rickart, EA Heaney, LR Balete, DS Tabaranza, BR
Vol 76
Issue 1
Start page 12
End page 21
Publication year 2011
Times cited 1
Abstract A faunal survey conducted along an elevational gradient in
Balbalasang-Balbalan National Park in northern Luzon Island,
Philippines, revealed 15 species of non-flying small mammals. Thirteen,
including 1 shrew and 12 murid rodents, are native species endemic to
the Philippines, 7 of which are endemic to northern Luzon. Two species
are non-native murid rodents that were restricted to disturbed
habitats. As seen elsewhere in the Philippines, species richness was
greatest in montane and mossy forest habitats at mid to high
elevations. Although species-rich, the Balbalasang gradient does not
include the full diversity of species known from the Central Cordillera
region. Comparative data from sites elsewhere on Luzon reveal that
total species richness is a function of local elevation, with more
species present in areas with higher mountain peaks. These patterns
reflect the fact that diversity of non-flying small mammals is
concentrated in highland areas where local assemblages include species
that differ in diel activity, spatial habitat use, and diet.
Numerically dominant species are members of a single murid clade, and
several of these are specialized predators of earthworms. Similarly
structured communities in the highlands of Mindanao include species
that are only distantly related to those of Luzon. Community
convergence is thought to reflect the influence of similar habitat
structure, food resource availability, and trophic partitioning in
shaping small mammal assemblages. (C) 2010 Deutsche Gesellschaft fur
Saugetierkunde. Published by Elsevier Gmbh. All rights reserved.
UT WOS:000287547700003
SN 1616-5047
doi 10.1016/j.mambio.2010.01.006

Publication type J
Title Coordinated Activation of Cellulose and Repression of Lignin
Biosynthesis Pathways in Rice
Author/s Ambavaram, MMR Krishnan, A Trijatmiko, KR Pereira, A
Vol 155
Issue 2
Start page 916
End page 931
Publication year 2011
Times cited 0
Abstract Cellulose from plant biomass is the largest renewable energy resource
of carbon fixed from the atmosphere, which can be converted into
fermentable sugars for production into ethanol. However, the cellulose
present as lignocellulosic biomass is embedded in a hemicellulose and
lignin matrix from which it needs to be extracted for efficient
processing. Here, we show that expression of an Arabidopsis
(Arabidopsis thaliana) transcription factor, SHINE (SHN), in rice
(Oryza sativa), a model for the grasses, causes a 34% increase in
cellulose and a 45% reduction in lignin content. The rice AtSHN lines
also exhibit an altered lignin composition correlated with improved
digestibility, with no compromise in plant strength and performance.
Using a detailed systems-level analysis of global gene expression in
rice, we reveal the SHN regulatory network coordinating down-regulation
of lignin biosynthesis and up-regulation of cellulose and other cell
wall biosynthesis pathway genes. The results thus support the
development of nonfood crops and crop wastes with increased cellulose
and low lignin with good agronomic performance that could improve the
economic viability of lignocellulosic crop utilization for biofuels.
UT WOS:000286880800023
SN 0032-0889
doi 10.1104/pp.110.168641

Publication type J
Title Chemical weathering, river geochemistry and atmospheric carbon fluxes
from volcanic and ultramafic regions on Luzon Island, the Philippines
Author/s Schopka, HH Derry, LA Arcilla, CA
Vol 75
Issue 4
Start page 978
End page 1002
Publication year 2011
Times cited 0
Abstract We investigated rates of chemical weathering of volcanic and ophiolitic
rocks on Luzon Island, the Philippines. Luzon has a tropical climate
and is volcanically and tectonically very active, all factors that
should enhance chemical weathering. Seventy-five rivers and streams (10
draining ophiolites, 65 draining volcanic bedrock) and two volcanic hot
springs were sampled and analyzed for major elements, alkalinity and
Sr-87/Sr-86. Cationic fluxes from the volcanic basins are dominated by
Ca2+ and Mg2+ and dissolved silica concentrations are high (500-1900 mu
M). Silica concentrations in streams draining ophiolites are lower
(400-900 mu M), and the cationic charge is mostly Mg2+. The areally
weighted average CO2 export flux from our study area is 3.89 +/- 0.21 x
10(6) mol/km(2)/yr, or 5.99 +/- 0.64 x 10(6) mol/km(2)/yr from
ophiolites and 3.58 +/- 0.23 x 10(6) mol/km(2)/yr from volcanic areas
(uncertainty given as +/- 1 standard error, s.e.). This is similar to
6-10 times higher than the current best estimate of areally averaged
global CO2 export by basalt chemical weathering and similar to 2-3
times higher than the current best estimate of CO2 export by basalt
chemical weathering in the tropics. Extrapolating our findings to all
tropical arcs, we estimate that around one tenth of all atmospheric
carbon exported via silicate weathering to the oceans annually is
processed in these environments, which amount to similar to 1% of the
global exorheic drainage area. Chemical weathering of volcanic terranes
in the tropics appears to make a disproportionately large impact on the
long-term carbon cycle. (C) 2010 Elsevier Ltd. All rights reserved.
UT WOS:000286960400003
SN 0016-7037
doi 10.1016/j.gca.2010.11.014

Publication type J
Title Two-step stacking in capillary zone electrophoresis featuring sweeping
and micelle to solvent stacking: II. Organic anions
Author/s Quirino, JP Guidote, AM
Vol 1218
Issue 7
Start page 1004
End page 1010
Publication year 2011
Times cited 0
Abstract Two-step stacking of organic anions by sweeping and micelle to solvent
stacking (MSS) using cationic cetyltrimethylammonium micelles in
co-electroosmotic flow (co-EOF) capillary zone electrophoresis (CZE) is
described. The co-EOF condition where the direction of the EOF is the
same as the test anions was satisfied by positive dynamic coating of a
fused silica capillary with hexadimethrine bromide. The strategy was as
follows. After conditioning the capillary with the background solution
(BGS), a micellar solution (MS) was injected before the sample solution
(S). The BGS, MS and S have similar conductivities. Voltage was applied
at negative polarity. The analytes in the micelle-free S zone were
swept by micelles from the MS. The swept analytes were brought by the
micelles to the MSS boundary where the second stacking step was induced
by the presence of organic solvent in the BGS. Finally was the
separation of concentrated analytes by CZE. The effect of electrolyte
concentration in the S. injection time of the MS and the S and
surfactant concentration in the MS were studied. A 20-29,17-33 and
18-21 times increase in peak height sensitivity was obtained for the
test hypolipidaemic drugs (gemfibrozil, fluvastatin and atorvastatin),
non-steroidal anti-inflammatory drugs (diflunisal, naproxen,
ketoprofen, indoprofen and indomethacin), and herbicides (mecoprop and
fenoprop), respectively. The LODs (S/N = 3) were from 0.05 to 0.55 mu
g/mL. The intraday and interday repeatabilities (%RSD, n = 12) in terms
of retention time, corrected peak area, and peak heights was less than
3.6, 8.9, and 10.8%, respectively. The application of sweeping and MSS
in co-EOF CZE together with a simple extraction procedure to a waste
water sample spiked with the test herbicides was also demonstrated.
Crown Copyright (C) 2010 Published by Elsevier B.V. All rights
UT WOS:000287281200016
SN 0021-9673
doi 10.1016/j.chroma.2010.12.095

Publication type J
Title Characterization of Au-metal nanoparticle-hybridized poly
(3,4-ethylenedioxythiophene) films for electrochromic devices
Author/s Lee, JS Choi, YJ Wang, SJ Park, HH Pyun, JC
Vol 208
Issue 1
Start page 81
End page 85
Publication year 2011
Times cited 0
Abstract In order to enhance the electrochromic properties of poly
(3,4-ethylenedioxythiophene) (PEDOT), Au/PEDOT nano-hybrid thin films
were prepared from a Au nanoparticle (Au NP),
3,4-ethylenedioxythiophene (EDOT), iron p-toluenesulfonate and
imidazole mixture. The incorporation of Au NPs slightly affected the
surface roughness of PEDOT films but had an important impact on the
conjugation length and packing density of PEDOT due to the physical
volume effect. An enhancement in the electrochromic properties of PEDOT
was obtained, in particular, a 50% reduction in the switching speed of
PEDOT with a blue shift of the maximum absorption peak in the ultra
violet-visible spectroscopic analysis. (C) WILEY-VCH Verlag GmbH & Co.
KGaA, Weinheim
UT WOS:000287295100011
SN 1862-6300
doi 10.1002/pssa.201026201

Publication type J
Title IBD Around the world: Comparing the epidemiology, diagnosis, and
treatment: Proceedings of the World Digestive Health Day 2010 –
Inflammatory bowel disease task force meeting
Author/s Baumgart, DC Bernstein, CN Abbas, Z Colombel, JF Day, AS D’Haens, G Dotan, I Goh, KLHibi, T Kozarek, RA Quigley, EMM Reinisch, W Sands, BE Sollano, JD Steinhart, H Steinwurz, FVatn, MH Yamamoto-Furusho, JK
Vol 17
Issue 2
Start page 639
End page 644
Publication year 2011
Times cited 0
Abstract Every May 29th the World Gastroenterology Organization (WGO) celebrates
World Digestive Health Day (WDHD) and initiates a worldwide public
health campaign through its 110 national societies and 50,000 members.
Each year focuses on a particular digestive disorder in order to
increase general public awareness of prevention and therapy. 2010 is
dedicated to inflammatory bowel disease (IBD). Upon this occasion a WGO
IBD task force was compiled from leading international specialists and
researchers. The task force also included members of the American
Gastroenterological Association (AGA), International Organization for
the Study of Inflammatory Diseases (IOIBD) and the European Crohn’s and
Colitis Organization (ECCO) of the United European Gastroenterology
Federation (UEGF). The goal of the task force was to bring together IBD
specialists from around the world to discuss the epidemiology,
diagnosis, and management of IBD within different regions. This is a
summary of the WGO task force meeting at the American
Gastroenterological Association’s (AGA) Digestive Disease Week, held in
New Orleans, Louisiana, USA, May, 2010. The expert panel identified the
most pressing issues in IBD worldwide: reliable epidemiological data,
global collaboration in clinical and basic research, the approach to
distinguishing intestinal tuberculosis from Crohn’s disease, access to
specialist care and access to the latest diagnostic and therapeutic
UT WOS:000287116500028
SN 1078-0998
doi 10.1002/ibd.21409

Publication type J
Title Ontogenetic habitat shift, population growth, and burrowing behavior of
the Indo-Pacific beach star, Archaster typicus (Echinodermata;
Author/s Bos, AR Gumanao, GS van Katwijk, MM Mueller, B Saceda, MM Tejada, RLP
Journal source MARINE BIOLOGY
Vol 158
Issue 3
Start page 639
End page 648
Publication year 2011
Times cited 0
Abstract Archaster typicus, a common sea star in Indo-Pacific regions, has been
a target for the ornamental trade, even though little is known about
its population biology. Spatial and temporal patterns of abundance and
size structure of A. typicus were studied in the Davao Gulf, the
Philippines (125A degrees 42.7’E, 7A degrees 0.6’N), from February 2008
to December 2009. Specimens of A. typicus were associated with
intertidal mangrove prop roots, seagrass meadows, sandy beaches, and
shoals. Among prop roots, specimens were significantly smaller and had
highest densities (131 ind. m(-2)) between November and March. High
organic matter in sediment and a relatively low predation rate seemed
to support juvenile life among mangroves. Size and density analyses
provided evidence that individuals gradually move to seagrass, sandy
habitats, and shoals as they age. Specimens were significantly larger
at a shoal (maximum radius R = 81 mm). New recruits were found between
August and November in both 2008 and 2009. Timing of recruitment and
population size frequencies confirmed a seasonal reproductive cycle.
Juveniles had relatively high growth rates (2-7 mm month(-1)) and may
reach an R of 20-25 mm after 1 year. Growth rates of larger specimens
(R > 30 mm) were generally < 2 mm month(-1). The activity pattern of A.
typicus was related to the tidal phase and not to time of day:
Specimens moved over the sediment surface during low tides and were
burrowed during high tides possibly avoiding predation. This is one of
the first studies to document an ontogenetic habitat shift for sea
stars and provides new biological information as a basis for management
of harvested A. typicus populations.
UT WOS:000287525100015
SN 0025-3162
doi 10.1007/s00227-010-1588-0

Publication type J
Title Gene Structures, Classification and Expression Models of the AP2/EREBP
Transcription Factor Family in Rice
Author/s Sharoni, AM Nuruzzaman, M Satoh, K Shimizu, T Kondoh, H Sasaya, T Choi, IR Omura, T Kikuchi, S
Vol 52
Issue 2
Start page 344
End page 360
Publication year 2011
Times cited 0
Abstract We identified 163 AP2/EREBP (APETALA2/ethylene-responsive
element-binding protein) genes in rice. We analyzed gene structures,
phylogenies, domain duplication, genome localizations and expression
profiles. Conserved amino acid residues and phylogeny construction
using the AP2/ERF conserved domain sequence suggest that in rice the
OsAP2/EREBP gene family can be classified broadly into four subfamilies
[AP2, RAV (related to ABI3/VP1), DREB (dehydration-responsive
element-binding protein) and ERF (ethylene-responsive factor)]. The
chromosomal localizations of the OsAP2/EREBP genes indicated 20
segmental duplication events involving 40 genes; 58 redundant
OsAP2/EREBP genes were involved in tandem duplication events. There
were fewer introns after segmental duplication. We investigated
expression profiles of this gene family under biotic stresses
[infection with rice viruses such as rice stripe virus (RSV), rice
tungro spherical virus (RTSV) and rice dwarf virus (RDV, three virus
strains S, O and D84)], and various abiotic stresses. Symptoms of virus
infection were more severe in RSV infection than in RTSV and RDV
infection. Responses to biotic stresses are novel findings and these
stresses enhance the ability to identify the best candidate genes for
further functional analysis. The genes of subgroup B-5 were not induced
under abiotic treatments whereas they were activated by the three RDV
strains. None of the genes of subgroups A-3 were differentially
expressed by any of the biotic stresses. Our 44K and 22K microarray
results suggest that 53 and 52 non-redundant genes in this family were
up-regulated in response to biotic and abiotic stresses, respectively.
We further examined the stress responsiveness of most genes by reverse
transcription-PCR. The study results should be useful in selecting
candidate genes from specific subgroups for functional analysis.
UT WOS:000287254000015
SN 0032-0781
doi 10.1093/pcp/pcq196

Publication type J
Title Robust Estimation of a Spatiotemporal Model with Structural Change
Author/s Bastero, RF Barrios, EB
Vol 40
Issue 3
Start page 448
End page 468
Publication year 2011
Times cited 0
Abstract A spatiotemporal model is postulated and estimated using a procedure
that infuses the forward search algorithm and maximum likelihood
estimation into the backfitting framework. The forward search algorithm
filters the effect of temporary structural change in the estimation of
covariate and spatial parameters. Simulation studies illustrate
capability of the method in producing robust estimates of the
parameters even in the presence of structural change. The method
provides good model fit even for small sample sizes in short time
series data and good predictions for a wide range of lengths of
contamination periods and levels of severity of contamination.
UT WOS:000287030700009
SN 0361-0918
doi 10.1080/03610918.2010.543298

Publication type J
Title Electropolymerized Molecularly Imprinted Polymer Films of a
Bis-Terthiophene Dendron: Folic Acid Quartz Crystal Microbalance Sensing
Author/s Apodaca, DC Pernites, RB Ponnapati, RR Del Mundo, FR Advincula, RC
Vol 3
Issue 2
Start page 191
End page 203
Publication year 2011
Times cited 0
Abstract A folic acid sensor was prepared via an electropolymerized molecularly
imprinted polymer (E-MIP) film of a bis-terthiophene dendron on a
quartz crystal microbalance (QCM). The cyclic voltammetry (CV)
electrodeposition of the imprinted polymer film was monitored by
electrochemical QCM or E-QCM, enabling in situ monitoring and
characterization of E-MIP film formation and the viscoelastic behavior
of the film. A key component of the E-MIP process is the use of a
bifunctional monomer design to precomplex with the template and
function as a cross-linker. The complex was electropolymerized Mid
cross linked by CV to form a polythiophene Matrix. Stable cavities were
formed that specifically fit the size and shape of the folic acid
template. The same substrate surface was used for folic acid sensing.
The predicted geometry of the 1:2 folic acid/terthiophene complex was
obtained through semiempirical AM1 quantum calculations. The analytical
performance, expressed through the figures of merit, of the sensor in
aqueous solutions of the analyte was investigated. A relatively good
linearity, R-2 = 0.985, was obtained within the concentration range
0-100 mu M folic acid. The detection limit was found to be equal to
15.4 mu M (6.8 mu g). The relative cross selectivity of the folic acid
imprinted polymer against the three molecules follows this trend:
pteroic acid (= 50%) > caffeine (= 41%) > theophylline (= 6%). The
potential and limitations of the E-MIP method were also discussed.
UT WOS:000287639400016
SN 1944-8244
doi 10.1021/am100805y

Publication type J
Title Responses of Contrasting Rice (Oryza sativa L.) Genotypes to Salt
Stress as Affected by Nutrient Concentrations
Author/s Zhang, ZH Liu, QA Song, HX Rong, XM Ismail, AM
Vol 10
Issue 2
Start page 195
End page 206
Publication year 2011
Times cited 0
Abstract The study was conducted to investigate the effects of applying
different concentrations of the macronutrients K+, Ca2+, and Mg2+ on
the responses of contrasting rice (Oryza sativa L.) genotypes under
salt stress. A solution culture experiment was conducted in a phytotron
at the International Rice Research Institute (IRRI), under controlled
temperature and humidity and natural sunlight. When subjected to salt
stress of 100 mmol L-1 using NaCl, the salt tolerant genotypes FL478
and IR1651, accumulated less Na+ and maintained lower ratios of Na+/K+,
Na+/Ca2+, and Na+/Mg2+ than the sensitive genotypes IR29 and Azucena.
These tolerant genotypes also had higher concentrations of K+ in their
shoots and greater root and shoot biomass and green leaf area. Tolerant
genotypes also maintained much lower concentration of Na+ and lower and
more favorable ratios of Na+/K+, Na+/Ca2+, and Na+/Mg2+ in their active
and developing tissues. Salt tolerance and shoot and root growth of
both tolerant and sensitive genotypes were enhanced considerably when
higher concentrations of Ca2+ and Mg2+ were applied in culture
solution. The concentration of Na+ and the ratios of Na+/K+, Na+/Ca2+,
and Na+/Mg2+ in shoots also declined significantly. The beneficial
effects of higher calcium were greater than that of magnesium and
application of higher concentration of K+ seems to have minor effects.
Responses to salinity in rice can therefore be considerably enhanced
through proper nutrient management, by increasing the concentrations of
nutrient elements that have favorable effects such as Ca2+ and Mg2+.
Calcium is particularly more effective than both magnesium and
potassium, and can be applied at relatively larger quantities in salt
affected soils.
UT WOS:000287644200005
SN 1671-2927
doi 10.1016/S1671-2927(09)60306-0

Publication type J
Title Global CO2 emission from volcanic lakes
Author/s Perez, NM Hernandez, PA Padilla, G Nolasco, D Barrancos, J Melian, G Padron, E Dionis, S Calvo, DRodriguez, F Notsu, K Mori, T Kusakabe, M Arpa, MC Reniva, P Ibarra, M
Journal source GEOLOGY
Vol 39
Issue 3
Start page 235
End page 238
Publication year 2011
Times cited 0
Abstract The global CO2 discharge from subaerial volcanism has been estimated at
similar to 300 Mt yr(-1). However, estimates of CO2 emissions from
volcanic lakes have not been considered. In order to improve this
information, extensive research on CO2 emissions of volcanic lakes
worldwide has been performed. The observed normalized average CO2
emission rates increase from alkaline (5.5 t km(-2) d(-1)), to neutral
(201.2 t km(-2) d(-1)), to acid (614.2 t km(-2) d(-1)) in volcanic
lakes. Taking into account (1) normalized CO2 emission rates, (2) the
number of volcanic lakes in the world (similar to 769), and (3) the
fraction and average areas of the investigated alkaline, neutral, and
acid volcanic lakes, the estimated global CO2 emission from volcanic
lakes is 117 +/- 19 Mt yr(-1), with 94 +/- 17 Mt yr(-1) as deep-seated
CO2. This study highlights the importance of a revision of the actual
global CO2 discharge from subaerial volcanism.
UT WOS:000287374900013
SN 0091-7613
doi 10.1130/G31586.1

Publication type J
Author/s Fuiten, AM Welton, LJ Diesmos, AC Barley, AJ Oberheide, B Duya, MV Rico, ELB Brown, RM
Journal source HERPETOLOGICA
Vol 67
Issue 1
Start page 89
End page 103
Publication year 2011
Times cited 0
Abstract We describe a distinctively patterned new species of cascade stream
frog from the mountains of Nueva Vizcaya and Aurora provinces, Luzon
Island. The new species belongs to the genus Sanguirana, the definition
of which we expand to include all Philippine species previously
referred to the Rana (Hylarana) everetti complex. The new species is
distinguished from other members of the genus by its possession of a
bright yellow-green dorsum with conspicuous orange flower-shaped spots
in females, bright white, postaxial dermal flanges on the limbs,
green-to-purple flank transition, and a highly tuberculate, white
venter, in addition to the absence of a Clark canthal stripe. The new
species is known only from high-gradient, cascading mountain streams
between elevations of 750 and 1450 m in mature secondaly forest and
minimally disturbed primary forests. The discovery of such a
distinctive new species emphasizes the relatively high degree to which
endemic anuran diversity in the Philippines is still underestimated and
UT WOS:000287640100009
SN 0018-0831

Publication type J
Title Comparison of oleyl and elaidyl isomer surfactant-counterion systems in
drag reduction, rheological properties and nanostructure
Author/s Qi, YY Kesselman, E Hart, DJ Talmon, Y Mateo, A Zakin, JL
Vol 354
Issue 2
Start page 691
End page 699
Publication year 2011
Times cited 0
Abstract Compared with quaternary ammonium cationic surfactants with saturated
alkyl chains, quaternary ammonium cationic surfactants with one
double-bond in their alkyl chains, when mixed with appropriate
counterions (in certain molar concentration ratios, xi), can reach much
lower effective drag-reduction temperatures, while maintaining the
upper drag-reduction temperature limit of the corresponding saturated
drag reducing surfactant solutions. No previous study has compared the
effects of cis- vs. trans-unsaturated alkyl hydrocarbon tail
configurations (oleyl vs. elaidyl) trimethyl ammonium chloride cationic
surfactants at different counterion/surfactant concentration ratios on
micellar nanostructures, H-1 NMR spectra and on theological and
drag-reduction behavior of their solutions. Since neither pure oleyl
(cis-) nor elaidyl (trans-) trimethyl ammonium chloride surfactants are
commercially available, they were synthesized and their 5 mM solutions
with NaSaI counterion at concentrations of 5 mM, 7.5 mM and 12.5 mM
were studied. (C) 2010 Elsevier Inc. All rights reserved.
UT WOS:000286157000036
SN 0021-9797
doi 10.1016/j.jcis.2010.10.067

Publication type J
Title Analysis of Antibody Responses to Mycobacterium leprae Phenolic
Glycolipid I, Lipoarabinomannan, and Recombinant Proteins To Define
Disease Subtype-Specific Antigenic Profiles in Leprosy
Author/s Spencer, JS Kim, HJ Wheat, WH Chatterjee, D Balagon, MV Cellona, RV Tan, EV Gelber, RSaunderson, P Duthie, MS Reece, ST Burman, W Belknap, R Mac Kenzie, WR Geluk, A Oskam, LDockrell, HM Brennan, PJ
Vol 18
Issue 2
Start page 260
End page 267
Publication year 2011
Times cited 0
Abstract A simple serodiagnostic test based on the Mycobacterium leprae-specific
phenolic glycolipid I(PGL-I), for individuals with leprosy is nearly
universally positive in leprosy patients with high bacillary loads but
cannot be used as a stand-alone diagnostic test for the entire spectrum
of the disease process. For patients with early infection with no
detectable acid-fast bacilli in lesions or with low or no antibody
titer to PGL-I, as in those at the tuberculoid end of the disease
spectrum, this diagnostic approach has limited usefulness. To identify
additional M. leprae antigens that might enhance the serological
detection of these individuals, we have examined the reactivity
patterns of patient sera to PGL-I, lipoarabinomannan (LAM), and six
recombinant M. leprae proteins (ML1877, ML0841, ML2028, ML2038, ML0380,
and ML0050) by Western blot analysis and enzyme-linked immunosorbent
assay (ELISA). Overall, the responses to ML2028 (Ag85B) and ML2038
(bacterioferritin) were consistently high in both multibacillary and
paucibacillary groups and weak or absent in endemic controls, while
responses to other antigens showed considerable variability, from
strongly positive to completely negative. This analysis has given a
clearer understanding of some of the differences in the antibody
responses between individuals at opposite ends of the disease spectrum,
as well as illustrating the heterogeneity of antibody responses toward
protein, carbohydrate, and glycolipid antigens within a clinical group.
Correlating these response patterns with a particular disease state
could allow for a more critical assessment of the form of disease
within the leprosy spectrum and could lead to better patient
UT WOS:000286653900011
SN 1556-6811
doi 10.1128/CVI.00472-10

Publication type J
Title The implications of land preparation, crop establishment method and
weed management on rice yield variation in the rice-wheat system in the
Indo-Gangetic plains
Author/s Singh, Y Singh, VP Singh, G Yadav, DS Sinha, RKP Johnson, DE Mortimer, AM
Vol 121
Issue 1
Start page 64
End page 74
Publication year 2011
Times cited 0
Abstract The implications of adopting alternative seeding methods for rice and
wheat establishment were examined at three geographically separate
sites in the rice-wheat system of the Indo-Gangetic plains, across
northern India. Rice yields in cultivated plots, established by either
wet or dry seeding methods, were evaluated in comparison to yields from
zero-tillage plots and under conventional transplanting methods. In the
same trials, the effects of crop establishment methods in wheat were
assessed both on wheat yields and rice yields. Rice crop establishment
methods markedly influenced the emerging weed flora and attainable
yields were measured in relation to intensity of weed management. Over
four years, average rice grain yields in the absence of weed
competition were greatest (6.56 t ha(-1)) under wet seeding (sowing
pre-germinated rice seed on puddled soil), and similar to those from
transplanted rice (6.17 t ha(-1)) into puddled soil, and dry seeded
rice after dry soil tillage (6.15 t ha(-1)). Lowest yields were
observed from dry seeded rice sown without tillage (5.44 t ha(-1)).
Rice yield losses due to uncontrolled weed growth were least in
transplanted rice (12%) but otherwise large (c. 85%) where rice had
been sown to dry cultivated fields or to puddled soil, rising to 98% in
dry seeded rice sown without soil tillage. Weed competition reduced
multiple rice yield components, and weed biomass in wet seeded rice was
six-fold greater that in rice transplanted into puddled soil and twice
as much again in dry seeded rice sown either after dry tillage or
without tillage. Wheat grain yields were significantly higher from
crops sown into tilled soil (3.89 t ha(-1)) than those sown without
tillage (3.51 t ha(-1)), and also were elevated (5% on average) where
the soil had been dry cultivated in preparation for the previous rice
crops rather than puddled. The method of wheat cultivation did not
influence rice yield. Soil infiltration rates in the wheat season were
least where the land had been puddled for rice (1.52 mm h(-1)), and
greater where the soil had been dry-tilled (2.63 mm h(-1)) and greatest
after zero-tillage (3.54 mm h(-1)).
These studies demonstrated at research managed sites across a wide
geographic area, and on farmers’ fields, that yields of dry seeded rice
sown after dry cultivation of soil were broadly comparable with those
of transplanted rice, providing weed competition was absent. These
results support the proposition that direct seeding of rice could
provide an alternative to the conventional practice of transplanting,
and help address rising costs and threats to sustainability in the
rice-wheat rotation. Further, analysis of patterns of long-term
rainfall data indicated that farmers reliant on monsoon rainfall could
prepare fields for dry direct seeded rice some 30 days before they
could prepare fields for either transplanting or seeding with
pre-germinated seed. Dry, direct seeding of rice contributes a valuable
component of an adaptive strategy to address monsoonal variability that
also may advance the time of wheat establishment and yield. Whilst the
results illustrate the robustness, feasibility and significant
potential of direct seeded rice, they also highlight the critical
nature of effective weed control in successful implementation of direct
seeding systems for rice. (C) 2010 Elsevier B.V. All rights reserved.
UT WOS:000287567200006
SN 0378-4290
doi 10.1016/j.fcr.2010.11.012

Publication type J
Title Relations of rice seeding rates to crop and weed growth in aerobic rice
Author/s Chauhan, BS Singh, VP Kumar, A Johnson, DE
Vol 121
Issue 1
Start page 105
End page 115
Publication year 2011
Times cited 1
Abstract Aerobic rice describes a management adaptation to reduced irrigation
water supplies but, due to reduced intervals of flooding in this
system, this requires revised weed management approaches to reduce
costs and provide effective weed control. One approach is to make the
crop more competitive and reduce the effects of weeds on the crop by
using higher rice seeding rates. A study was conducted in the
Philippines and India in 2008 and 2009 to assess the relations of
seeding rates (15-125 kg ha(-1)) of hybrid and inbred varieties to crop
and weed growth in aerobic rice. Plant densities, tillers, and biomass
of rice increased linearly with increased in seeding rates under both
weedy and weed free environments. Weed biomass decreased linearly with
increasing seeding rates from 15 to 125 kg ha(-1). Panicles and grain
yields of rice in competition with weeds increased in a quadratic
relation with increased seeding rates at both locations; however, the
response was flat in the weed free plots. A quadratic model predicted
that seeding rates of 48-80 kg ha(-1) for the inbred varieties and
47-67 kg ha(-1) for the hybrid varieties were needed to achieve maximum
grain yield when grown in the absence of weeds, while rates of 95-125
kg seed ha(-1) for the inbred varieties and 83-92 kg seed ha(-1) for
the hybrid varieties were needed to achieve maximum yields in
competition with weeds. On the basis of these results, seeding rates
greater than 80 kg ha(-1) are advisable where there are risks of severe
weed competition. Such high seeding rates may be prohibitive when using
expensive seed, and maximum yields are not the only consideration for
developing recommendations for optimizing economic returns for farmers.
Results of the present study do suggest however that increasing seeding
rates of aerobic rice does suppress weed growth and reduce grain yield
losses from weed competition. This information could be incorporated in
integrated crop management packages to manage weeds more effectively.
(C) 2010 Elsevier B.V. All rights reserved.
UT WOS:000287567200010
SN 0378-4290
doi 10.1016/j.fcr.2010.11.019

Publication type J
Title Chlorophyll meter-based nitrogen management of rice grown under
alternate wetting and drying irrigation
Author/s Cabangon, RJ Castillo, EG Tuong, TP
Vol 121
Issue 1
Start page 136
End page 146
Publication year 2011
Times cited 0
Abstract Farmers have adopted alternate wetting and drying (AWD) irrigation to
cope with water scarcity in rice production. This practice shifts rice
land away from being continuously anaerobic to being partly aerobic,
thus affecting nutrient availability to the rice plant, and requiring
some adjustment in nutrient management. The use of a chlorophyll meter
(also known as a SPAD meter) has been proven effective in increasing
nitrogen-use efficiency (NUE) in continuously flooded (CF) rice, but
its use has not been investigated under AWD irrigation. This study
aimed at testing the hypotheses that (i) SPAD-based N management can be
applied to AWD in the same way it is used in CF rice, and (ii)
combining chlorophyll meter-based nitrogen management and AWD can
enhance NUE, save water, and maintain high rice yield. Experiments were
conducted in a split-plot design with four replications in the 2004 and
2005 dry seasons (DS) at IRRI. The main plots were three water
treatments: CF, AWD that involved irrigation application when the soil
dried to soil water potential at 15-cm depth of -20 kPa (AWD(-20)) and
-80 kPa (AWD(-80)) in 2004, and AWD(-10) and AWD(-50) were used in
2005. The subplots were five N management treatments: zero N (N-0), 180
kg N ha(-1) in four splits (N-180), and three SPAD-based N-management
treatments in which N was applied when the SPAD reading of the youngest
fully extended leaf was less than or equaled 35 (N-SPAD35), 38
(N-SPAD38), and 41 (N-SPAD41). In 2005. N-SPAD32 was tested instead of
N-SPAD41. A good correlation between leaf N content per unit leaf area
and the SPAD reading was observed for all water treatments, suggesting
that the SPAD reading can be used to estimate leaf N of rice grown
under AWD in a way similar to that under CF.SPAD readings and leaf
color chart (LCC) values also showed a good correlation. There were no
water x nitrogen interactive effects on rice yield, water input, water
productivity, and N-use efficiency. Rice yield in AWD(-10) was similar
to those of CF; yields of other AWD treatments were significantly lower
than those of CF.AWD(-10) reduced irrigation water input by 20% and
significantly increased water productivity compared with CF. The
apparent nitrogen recovery and agronomic N-use efficiency (ANUE) of
AWD(-10) and AWD(-20) were similar to those of CF. The ANUE of N-SPAD38
and N-SPAD35 was consistently higher than that of N-180 in all water
treatments. N-SPAD38 consistently gave yield similar to that of N-180
in all water treatments, while yield of N-SPAD35 about 90% of that of
CF. We conclude that a combination of AWD(-10) and SPAD-based N
management, using critical value 38, can save irrigation water and N
fertilizer while maintaining high yield as in CF conditions with fixed
time and rate of nitrogen application of 180 kg ha(-1). Treatments
AWD(-20) and N-SPAD35 may be accepted by farmers when water and N
fertilizer are scarce and costly. The findings also suggested LCC can
also be a practical tool for N-fertilizer management of rice grown
under AWD, but this needs further field validation. (C) 2010 Elsevier
B.V. All rights reserved.
UT WOS:000287567200013
SN 0378-4290
doi 10.1016/j.fcr.2010.12.002

Publication type J
Title Agronomic performance of rice breeding lines selected based on plant
traits or grain yield
Author/s Yuan, WL Peng, SB Cao, CG Virk, P Xing, DY Zhang, YB Visperas, RM Laza, RC
Vol 121
Issue 1
Start page 168
End page 174
Publication year 2011
Times cited 0
Abstract Selection for yield per se has greatly contributed to yield improvement
in many crops. It is expected that selection based on plant traits is
more effective in increasing crop yield potential. This study was
conducted to compare the effectiveness of trait-based and yield-based
selection in increasing rice yield and to determine whether lines with
ideotype traits have the potential to express higher yield under
optimal crop management conditions. Lines were selected based on plant
traits or on grain yield measured in a breeder’s replicated yield
trial. The main target traits for selection were plant height, leaf and
panicle morphology, grain size, total dry weight, and grain-filling
percentage. Yield performance of trait-based selection was compared
with that of yield-based selection in an agronomic trial with optimum
crop management for three seasons. Trait-based selection increased leaf
area index and total dry weight but reduced spikelet number per m(2)
and harvest index compared with yield-based selection. Consequently,
selection based on plant traits did not increase grain yield compared
with selection based on yield per se. In one of the three seasons,
yield of trait-based selection was significantly lower than that of
yield-based selection. Among all tested breeding lines, maximum yield
was produced by yield-based selection and minimum yield came from
trait-based selection. These results suggest that lines with ideotype
traits did not express higher grain yield than lines selected based on
yield per se under optimal crop management conditions, and yield-based
selection was as effective in increasing rice grain yield as
trait-based selection in the late generations of the breeding cycle.
(C) 2011 Published by Elsevier B.V.
UT WOS:000287567200017
SN 0378-4290
doi 10.1016/j.fcr.2010.12.014

Publication type J
Title Global fishing effort (1950-2010): Trends, gaps, and implications
Author/s Anticamara, JA Watson, R Gelchu, A Pauly, D
Vol 107
Issue 1-3
Start page 131
End page 136
Publication year 2011
Times cited 0
Abstract According to a recent World Bank report, the intensification of global
fishing effort and the ensuing depletion of marine fish stocks causes
economic losses of 50 billion US dollars annually. Data deficiencies,
however, currently hamper analysis of global fishing effort. We
analyzed data from the Food and Agricultural Organization of the United
Nations (FAO), the EUROPA fishing fleet registry, and peer-reviewed and
other publications, to determine the global trends in fishing effort
from 1950 to 2006. Our results show that global fishing effort,
expressed as total engine power and the number of fishing days in a
year (kilowatt days), was roughly constant from 1950 to 1970, and then
steadily increased up to the present. Europe dominated global fishing
effort, followed by Asia. Projecting current trends suggests that Asia
will soon surpass Europe. Trawlers contribute a major fraction of
global fishing effort, as do vessels greater than 100 gross registered
tons. Current estimates of global fishing effort, the number of
vessels, and total vessel tonnage are, however, underestimates given
the data gaps that we have identified. Our results are useful in the
following ways: (1) they may encourage researchers in academia and
government to improve global fishing effort databases; (2) they allow
deeper global analyses of the impact of fishing on marine ecosystems;
(3) they induce caution in accepting current underestimates of economic
losses of global fisheries; and (4) they reinforce calls for a
reduction in global fishing effort. (C) 2010 Elsevier B.V. All rights
UT WOS:000287113600014
SN 0165-7836
doi 10.1016/j.fishres.2010.10.016

Publication type J
Title A new drug for managing both nasal and ocular symptoms of allergic
rhinitis: Fluticasone furoate nasal spray
Author/s Enoz, M Inancli, HM Lapena, JF Hafiz, G
Vol 75
Issue 1
Start page 140
End page 140
Publication year 2011
Times cited 0
UT WOS:000287065800029
SN 0165-5876
doi 10.1016/j.ijporl.2010.02.018

Publication type J
Title Tissue Inhibitor of Matrix-Metalloprotease-1 Predicts Risk of Hepatic
Fibrosis in Human Schistosoma japonicum Infection
Author/s Fabre, V Wu, HW Pond Tor, S Coutinho, H Acosta, L Jiz, M Olveda, R Cheng, L White, ES Jarilla, B McGarvey, ST Friedman, JF Kurtis, JD
Vol 203
Issue 5
Start page 707
End page 714
Publication year 2011
Times cited 0
Abstract Methods. We treated 611 Schistosoma japonicum-infected Filipinos with
praziquantel (PZQ) and performed ultrasound to quantify hepatic
fibrosis at baseline and 12 months after PZQ treatment. We developed a
multiplexed assay (FibroPlex) that quantifies predictors and effect
modifiers of fibrosis. We measured FibroPlex analytes produced by
peripheral blood mononuclear cells stimulated with schistosome egg
antigen 4 weeks after PZQ treatment and related these levels to risk of
fibrosis 1 year after PZQ treatment.
Results. After adjusting for potential confounders, including baseline
grade of fibrosis, individuals with detectable tissue inhibitor of
matrix-metalloprotease-1 (TIMP-1) had a 3.5-fold greater risk of
fibrosis 1 year after PZQ treatment, compared with individuals with
undetectable levels (odds ratio, 3.48; 95% confidence interval,
1.41-8.43; P = .007).
Discussion Because TIMP-1 inhibits most matrix metalloproteases, which
are responsible for collagen degradation, these data suggest that
schistosome-associated hepatic fibrosis results, in part, from
excessive inhibition of collagen remodeling. These data further suggest
that TIMP-1 is a promising biomarker for assessing risk of hepatic
fibrosis in schistosomiasis and, potentially, other infectious and
noninfectious causes of liver disease.
UT WOS:000287028000018
SN 0022-1899
doi 10.1093/infdis/jiq099

Publication type J
Title Thermal stability and moisture uptake of 1-alkyl-3-methylimidazolium
Author/s Arellano, IHJ Guarino, JG Paredes, FU Arco, SD
Vol 103
Issue 2
Start page 725
End page 730
Publication year 2011
Times cited 1
Abstract The thermal stability of the ionic liquids (ILs)
1-n-butyl-3-methylimidazolium bromide, [BMIM]Br, and
1-n-octyl-3-methylimidazolium bromide, [OMIM]Br, was evaluated through
thermogravimetry (TG). Long-term isothermal TG studies revealed that
both of these ILs exhibit appreciable decomposition even at
temperatures significantly lower than the onset decomposition
temperature, previously determined from fast scan TG experiments. The
long-term TG studies of both the ILs showed linear mass loss as a
function of time at each temperature of 10 A degrees C interval in the
range 533-573 K over a period of 10 h. The kinetics of isothermal
decomposition of ILs was analyzed using pseudo-zero-order rate
expression. The activation energies for the isothermal decomposition of
[BMIM]Br and [OMIM]Br under nitrogen atmosphere are 219.86 and 212.50
kJ mol(-1), respectively. The moisture absorption kinetics of these ILs
at 25 A degrees C and 30% relative humidity (RH) and at 85 A degrees C
and 85% RH were also studied. Water uptake of ILs exposed at 25 A
degrees C/30%RH follows a simple saturation behavior in agreement with
Weibull model while that at 85 A degrees C/85%RH fortuitously fit into
the Henderson-Pabis model.
UT WOS:000286836000041
SN 1388-6150
doi 10.1007/s10973-010-0992-5

Publication type J
Title Decomposition Rates and Residue-Colonizing Microbial Communities of
Bacillus thuringiensis Insecticidal Protein Cry3Bb-Expressing (Bt) and
Non-Bt Corn Hybrids in the Field
Author/s Xue, K Serohijos, RC Devare, M Thies, JE
Vol 77
Issue 3
Start page 839
End page 846
Publication year 2011
Times cited 0
Abstract Despite the rapid adoption of crops expressing the insecticidal Cry
protein(s) from Bacillus thuringiensis (Bt), public concern continues
to mount over the potential environmental impacts. Reduced residue
decomposition rates and increased tissue lignin concentrations reported
for some Bt corn hybrids have been highlighted recently as they may
influence soil carbon dynamics. We assessed the effects of MON863 Bt
corn, producing the Cry3Bb protein against the corn rootworm complex,
on these aspects and associated decomposer communities by terminal
restriction fragment length polymorphism (T-RFLP) analysis. Litterbags
containing cobs, roots, or stalks plus leaves from Bt and unmodified
corn with (non-Bt + I) or without (non-Bt) insecticide applied were
placed on the soil surface and at a 10-cm depth in field plots planted
with these crop treatments. The litterbags were recovered and analyzed
after 3.5, 15.5, and 25 months. No significant effect of treatment (Bt,
non-Bt, and non-Bt + I) was observed on initial tissue lignin
concentrations, litter decomposition rate, or bacterial decomposer
communities. The effect of treatment on fungal decomposer communities
was minor, with only 1 of 16 comparisons yielding separation by
treatment. Environmental factors (litterbag recovery year, litterbag
placement, and plot history) led to significant differences for most
measured variables. Combined, these results indicate that the
differences detected were driven primarily by environmental factors
rather than by any differences between the corn hybrids or the use of
tefluthrin. We conclude that the Cry3Bb corn tested in this study is
unlikely to affect carbon residence time or turnover in soils receiving
these crop residues.
UT WOS:000286597100017
SN 0099-2240
doi 10.1128/AEM.01954-10

Publication type J
Title Effect of an alpha-lactalbumin-enriched infant formula with lower
protein on growth
Author/s Trabulsi, J Capeding, R Lebumfacil, J Ramanujam, K Feng, P McSweeney, S Harris, B DeRusso, P
Vol 65
Issue 2
Start page 167
End page 174
Publication year 2011
Times cited 0
Abstract Background/Objectives: Protein concentration is lower in human milk
(HM) than in infant formula. The objective of this study was to
evaluate the effect of an alpha-lactalbumin-enriched formula with a
lower protein concentration on infant growth, protein markers and
Subjects/Methods: Healthy term formula-fed (FF) infants 5-14 days old
were randomized in this controlled, double-blind trial to standard
formula (SF: 14.1 g/l protein, 662 kcal/l) group (n = 112) or
experimental formula (EF: 12.8 g/l protein, 662 kcal/l) group (n = 112)
for 120 days; a HM reference group (n = 112) was included. Primary
outcome was weight gain (g/day) from D0 to D120. Secondary outcomes
included serum albumin, plasma amino acids insulin and incidence of
study events. Anthropometric measures were expressed as Z-scores using
2006 World Health Organization growth standards.
Results: A total of 321 of the 336 infants (96%) who enrolled,
completed the study. Mean age was 9.6 (+/- 2.9) days; 50% were girls.
Mean weight gain (g/day) did not significantly differ between SF vs EF
(P=0.67) nor between EF vs HM (P=0.11); however weight gain (g/day) was
significantly greater in the SF vs HM group (P-0.04). At day 120, mean
weight-for-age Z-score (WAZ) and weight-for-length Z-score (WLZ) did
not significantly differ between SF vs EF nor EF vs HM; however the WAZ
was significantly greater in SF vs HM (P=0.025). Secondary outcomes
were within normal ranges for all groups. Incidence of study events did
not differ among groups.
Conclusions: alpha-Lactalbumin-enriched formula containing1 2.8 g/l
protein was safe and supported age-appropriate growth; weight gain with
EF was intermediate between SF and HM groups and resulted in growth
similar to HM-fed infants in terms of weight gain, WAZ and WLZ.
European Journal of Clinical Nutrition (2011) 65, 167-174;
doi:10.1038/ejcn.2010.236; published online 10 November 2010
UT WOS:000286875300004
SN 0954-3007
doi 10.1038/ejcn.2010.236

Publication type J
Title Nitrogen Response and Economics for Irrigated Corn in Nebraska
Author/s Dobermann, A Wortmann, CS Ferguson, RB Hergert, GW Shapiro, CA Tarkalson, DD Walters, DT
Vol 103
Issue 1
Start page 67
End page 75
Publication year 2011
Times cited 1
Abstract Nitrogen management recommendations may change as yield levels and
efficiency of crop production increase. The mean yield with nutrients
applied in 32 irrigated corn (Zea mays L.) trials conducted across
Nebraska from 2002 to 2004 to evaluate crop response to split-applied N
was 14.8 Mg ha(-1). The mean economically optimal nitrogen rates (EONR)
for irrigated corn varied with the fertilizer N/grain price ratio. At a
fertilizer N/corn price ratio of 7 the EONR was 171, 122, and 93 kg
ha(-1), respectively, for cropping systems with corn following corn
(CC), soybean [Glycine max (L.) Merr.] (CS), and drybean (Phaseolus
vulgaris L.) (CD). At this price ratio the present University of
Nebraska (UNL) recommendation procedure gave mean N recommendations
that were 17.2 and 68.1 kg ha(-1) higher than the mean EONR determined
in this study for CC and CD, respectively, but essentially equal to
mean EONR for CS. The UNL algorithm, adjusted for mean cropping system
EONR gave more accurate prediction of site-year EONR than alternative N
rate predictions for CC and CD with returns to applied nitrogen (RTN)
of -$22 and -$13 ha(-1) compared with measured site-year EONR.
Prediction of site-year EONR using mean EONR adjusted for soil organic
matter was more accurate for CS than other methods with an RTN of -$6
ha(-1) compared with measured site-year EONR. Further research is
needed to extend the results to: lower yield situations, alternatives
to split application of N, and adjustment of EONR to protect against
inadequate N in atypical seasons or for environmental protection.
UT WOS:000286000700010
SN 0002-1962
doi 10.2134/agronj2010.0179

Publication type J
Title Nitrogen Use Efficiency of Irrigated Corn for Three Cropping Systems in
Author/s Wortmann, CS Tarkalson, DD Shapiro, CA Dobermann, AR Ferguson, RB Hergert, GW Walters, D
Vol 103
Issue 1
Start page 76
End page 84
Publication year 2011
Times cited 0
Abstract Nitrogen use efficiency (NUE) is of economic and environmental
importance. Components of NUE were evaluated at in 32 irrigated corn
(Zea mays L.) trials conducted across Nebraska with different N rates
and where the previous crop was either corn (CC), drybean (Phaseolus
vulgaris L.) (CD), or soybean [Glycine max (L.) Merr.] (CS). The mean
grain yield with adequate nutrient availability was 14.7 Mg ha(-1).
When no N was applied, measured soil properties and irrigation water N
accounted for <20% of the variation in plant nitrogen uptake (UN). Mean
fertilizer N recovery in aboveground biomass was 74% at the lowest N
rate compared with 40% at the highest N rate, a mean of 64% at the
economically optimal nitrogen rate (EONR), and least with CD. Agronomic
efficiency of fertilizer N averaged 29 kg grain kg(-1) N at EONR and
was also least with CD. Partial factor productivity of N averaged 100
kg grain kg(-1) N at EONR, and was greater with CS compared with CC and
CD. Aft er harvest, residual soil nitrate nitrogen (RSN) in the 0- to
1.2-m depth ranged from 21 to 121 kg ha(-1) and increased with N rate.
Mean RSN was 88, 59, and 59 kg ha(-1) for CD, CC, and CS, respectively.
High corn yields can be achieved with high NUE and low RSN by
management to maximize profitability in consideration of yield
potential, and by applying N at the right amount and time.
UT WOS:000286000700011
SN 0002-1962
doi 10.2134/agronj2010.0189

Publication type J
Title Maternal Schistosomiasis Japonica Is Associated with Maternal,
Placental, and Fetal Inflammation
Author/s Kurtis, JD Higashi, A Wu, HW Gundogan, F McDonald, EA Sharma, S PondTor, S Jarilla, B Sagliba, MJ Gonzal, A Olveda, R Acosta, L Friedman, JF
Vol 79
Issue 3
Start page 1254
End page 1261
Publication year 2011
Times cited 0
Abstract Schistosomes infect similar to 40 million women of childbearing age and
result in the elaboration of proinflammatory cytokines that have been
implicated in fetal growth restriction. In murine models and two
observational studies in humans, schistosome infection during pregnancy
was associated with reduced birth weight, although a recent treatment
trial in Schistosoma mansoni did not detect this association. We
conducted an observational study among 99 pregnant women living in an
area of Schistosoma japonicum endemicity in the Philippines. We
enrolled women at 32 weeks gestation and measured S. japonicum and
geohelminth infection intensity. We collected maternal peripheral blood
at 32 weeks gestation and placental and cord blood at delivery to
assess inflammatory status. At delivery, we collected a
placental-tissue sample and measured birth weight. In multivariate
models adjusted for geohelminths, maternal schistosomiasis was
associated with increased levels of inflammatory cytokines in maternal
peripheral (tumor necrosis factor alpha [TNF-alpha] and interleukin 10
[IL-10]), placental (TNF-alpha, IL-6, TNF-alpha receptor II [RII], and
IL-1 beta), and cord (IL-1 beta and TNF-alpha RII) blood, as well as
acute subchorionitis and increased TNF-alpha production by
syncytiotrophoblasts assessed by immunohistochemistry (all P < 0.05).
After adjusting for confounders, placental IL-1 beta, and TNF-alpha
production by syncytiotrophoblasts was independently associated with
decreased birth weight (both P < 0.05). Our data indicate that maternal
schistosomiasis results in a proinflammatory signature that is
detectable in maternal, placental, and fetal compartments, and a subset
of these responses are associated with decreased birth weight. This
potential mechanistic link between maternal schistosomiasis and poor
birth outcomes will contribute to the debate regarding treatment of
maternal schistosome infections.
UT WOS:000287700200028
SN 0019-9567
doi 10.1128/IAI.01072-10

Publication type J
Author/s Bonu, S Rani, M Peters, DH Baker, TD
Vol 23
Issue 1
Start page 42
End page 62
Publication year 2011
Times cited 0
Abstract The study investigates the effects of mandatory political
representation of women and non-forward castes in India (73rd
Constitutional Amendment) on development preferences and social equity.
We used systematic content analysis of proceedings from meetings of 155
rural village assemblies. The study revealed overemphasis on physical
infrastructure, relative neglect of health and education, influence of
state government directives and marginalisation of gender issues.
However, there was higher likelihood of articulation of non forward
caste-related issues by non-forward caste chairpersons. A paradigm
shift in the development perspective of local governments, stressing
investments in leadership development is needed. Copyright (C) 2009
John Wiley & Sons, Ltd.
UT WOS:000286294800003
SN 0954-1748
doi 10.1002/jid.1566

Publication type J
Title Health in Southeast Asia 4 The rise of chronic non-communicable
diseases in southeast Asia: time for action
Author/s Dans, A Ng, N Varghese, C Tai, ES Firestone, R Bonita, R
Journal source LANCET
Vol 377
Issue 9766
Start page 680
End page 689
Publication year 2011
Times cited 0
Abstract Southeast Asia faces an epidemic of chronic non-communicable diseases,
now responsible for 60% of deaths in the region. The problem stems from
environmental factors that promote tobacco use, unhealthy diet, and
inadequate physical activity. Disadvantaged populations are the hardest
hit, with death rates inversely proportional to a country’s gross
national income. Families shoulder the financial burden, but entire
economies suffer as well. Although attempts to control non-communicable
diseases are increasing, more needs to be done. Health-care systems
need to be redesigned to deliver chronic care that is founded on
existing primary health-care facilities, but supported by good referral
systems. Surveillance of key modifiable risk factors is needed to
monitor the magnitude of the problem and to study the effects of
interventions. All branches of government and all sectors of society
have to get involved in establishing environments that are conducive to
healthy living. The Association of Southeast Asian Nations is in a
unique position to make a united stand against chronic non-communicable
diseases in the region. Inaction will affect millions of lives often,
the lives of those who have the least.
UT WOS:000287776600038
SN 0140-6736
doi 10.1016/S0140-6736(10)61506-1

Publication type J
Title Infants Perceived as “Fussy” Are More Likely to Receive Complementary
Foods Before 4 Months
Author/s Wasser, H Bentley, M Borja, JG oldman, BD Thompson, A Slining, M Adair, L
Journal source PEDIATRICS
Vol 127
Issue 2
Start page 229
End page 237
Publication year 2011
Times cited 0
Abstract OBJECTIVE: Our purpose was to assess early infant-feeding patterns in a
cohort of low-income black mothers and to examine associations between
maternal perception of infant temperament and complementary feeding
(CF) before 4 months.
METHODS: We used cross-sectional data from the 3-month visit (n = 217)
of the Infant Care, Feeding and Risk of Obesity Study to assess
relationships between early feeding of solids or juice and 6 dimensions
of perceived infant temperament. Descriptive statistics were used to
assess infant-feeding patterns, and logistic regression models were fit
for each diet-temperament relationship found significant in the
bivariate analyses.
RESULTS: Seventy-seven percent of the infants were fed solid foods at 3
months, 25% were fed juice, and 6% were exclusively breastfed. In
multivariable analyses, 2 dimensions of perceived infant temperament
were associated with early feeding of solid foods
(distress-to-limitations odds ratio [OR]: 1.97 [95% confidence interval
(CI): 1.12-3.44]; activity-level OR: 1.75 [95% CI: 1.07-2.85]), whereas
1 dimension, low-intensity pleasure, was associated with early feeding
of juice (OR: 0.51 [95% CI: 0.34-0.78]). Maternal characteristics
significantly associated with early CF included breastfeeding, obesity,
and depressive symptoms.
CONCLUSIONS: Low-income black mothers may represent a priority
population for interventions aimed at improving adherence to optimal
infant feeding recommendations. That maternal perceptions of several
domains of perceived infant temperament are related to early CF
suggests that this is an important factor to include in future
observational research and in the design of interventions. Pediatrics
2011; 127: 229237
UT WOS:000286805200038
SN 0031-4005
doi 10.1542/peds.2010-0166

Publication type J
Title Surface Energies of Magnetic Recording Head Components
Author/s Abenojar, ECHerber, JPEnriquez, End page
Vol 41
Issue 3
Start page 587
End page 595
Publication year 2011
Times cited 0
Abstract The rate of material removal during fixed abrasive lapping is a
function of friction coefficient, the surface tension of the lubricant
and of the substrate, and the contact angles between the interfaces. In
this study, the authors measured the surface energies of materials
typically found in thin film magnetic recording heads using contact
angle measurements and the Lifshitz-van der Waals acid/base approach.
The different materials tested were NixFey, Al2O3, and Al2O3-TiC.
Sample preparation procedures were also considered. The chemical used
to wash the surface was observed to affect the measured substrate
surface energies. Surface energy values for samples washed with either
acetone or hexane showed comparable results. The NixFey gave the
highest measured surface energy (46.3-48.8 mJ m(-2)) followed by Al2O3
(44.1-45.3 mJ m(-2)) and Al2O3-TiC (43.3-45.3 mJ m(-2)). In contrast,
the oil-washed samples measured generally lower surface energy values.
The study characterized the interaction of two lubricant types against
the three materials. The oil-based lubricant spreads completely on
oil-washed samples mainly because of the low surface tension of the oil
(22.0 mJ m(-2)) and did not show measurable contact angles. In
comparison, the water-soluble lubricant ethylene glycol, due to its
higher surface tension (48.0 mJ m(-2)), formed higher contact angles
ranging from 47.2 to 59.6A degrees on the different substrates.
UT WOS:000287498400012
SN 1023-8883
doi 10.1007/s11249-010-9737-7

Publication type J
Title Implementing a national policy for hepatitis B birth dose vaccination
in Philippines: Lessons for improved delivery
Author/s Sobel, HL Mantaring, JB Cuevas, F Ducusin, JV Thorley, M Hennessey, KA Nyunt-U, S
Journal source VACCINE
Vol 29
Issue 5
Start page 941
End page 945
Publication year 2011
Times cited 0
Abstract Background: An estimated seven million Filipinos (10-12% of the
population) are chronically infected with hepatitis B virus (HBV).
Achieving high birth dose coverage with hepatitis B vaccine is critical
for achieving the World Health Organization’s Western Pacific Regional
goal of reducing the prevalence of chronic HBV among children 5 years
of age to <2% by 2012.
Methods: Seven months after the Philippines adopted a hepatitis B
vaccine birth dose policy, hospitals with the highest number of
deliveries were invited to participate in an assessment of
implementation of the birth dose policy. Additionally, in metro Manila
birth dose coverage was estimated before and after conducting a
training workshop and supervisory follow-up for practitioners
conducting home deliveries or deliveries at lying-in clinics.
Results: Of the country’s largest 150 hospitals in terms of authorized
bed capacity, 85(56%) were included in this assessment. These hospitals
had 55,719 deliveries during July-September 2007. Of these, 54% infants
had a documented birth dose; however, only 22% were vaccinated within
24 h of delivery. Having a copy of the hepatitis B vaccine vaccination
policy (prevalence odds ratio [pOR] = 4.7, 95% confidence interval [CI]
= 1.2-18.0), having standing orders pOR = 4.8, 95% Cl = 1.3-18.1 and
providing training pOR = 18.9, 95% CI = 5.3-67.0 were associated with
>50% birth dose coverage in a hospital. In metro-Manila, regardless of
place of birth, the training workshop and supervisory follow-up
significantly improved hepatitis B vaccine administration within 24h
after birth, increasing from 19% before to 74% after the training
workshop and follow-up.
Conclusions: Experience in the Philippines showed that actions by
national, regional and health facility policy makers such as
establishing national policies, distributing detailed and specific
guidelines, conducting effective training and supervision, and having
hospital standing orders substantially increased hepatitis B vaccine
birth dose coverage. (C) 2010 Elsevier Ltd. All rights reserved.
UT WOS:000287295800012
SN 0264-410X
doi 10.1016/j.vaccine.2010.11.047

Publication type J
Title Positive nitrogen balance of Acacia mangium woodlots as fallows in the
Philippines based on N-15 natural abundance data of N-2 fixation
Author/s Mercado, AR Van Noordwijk, M Cadisch, G
Vol 81
Issue 3
Start page 221
End page 233
Publication year 2011
Times cited 0
Abstract Nitrogen inputs from biological nitrogen fixation contribute to
productivity and sustainability of agroforestry systems but they need
to be able to offset export of N when trees are harvested. This study
assessed magnitudes of biological nitrogen fixation (natural N-15
abundance) and N balance of Acacia mangium woodlots grown in farmer’s
fields, and determined if N-2 fixation capacity was affected by tree
age. Tree biomass, standing litter, understory vegetation and soil
samplings were conducted in 15 farmer’s fields growing A. mangium as a
form of sequential agroforestry in Claveria, Misamis Oriental,
Philippines. The trees corresponded to ages of 4, 6, 8, 10 and 12
years, and were replicated three times. Samples from different plant
parts and soils (0-100 cm) were collected and analyzed for delta N-15
and nutrients. The B-value, needed as a reference of isotopic
discrimination when fully reliant on atmospheric N, was generated by
growing A. mangium in an N-2-free sand culture in the glasshouse.
Isotopic discrimination occurring during N-2 fixation and metabolic
processes indicated variation of delta N-15 values in the order of
nodules > old leaves > young leaves > stems > litterfall and roots of
the trees grown in the field, with values ranging from -0.8 to 3.5aEuro
degrees except nodules which were enriched and significantly different
from other plant parts (P < 0.0001). Isotopic discrimination was not
affected by tree age (P > 0.05). Plants grown in N free sand culture
exhibited the same pattern of isotopic discrimination as plants grown
in the field. The estimated B-value for the whole plant of A. mangium
was -0.86aEuro degrees. Mature tree stands of 12 years accumulated up
to 1994 kg N ha(-1) in aboveground biomass. Average proportion of N
derived from N-2 fixation of A. mangium was 54% (+/- 22) and was not
affected by age (P > 0.05). Average yearly quantities of N-2 fixed were
128 kg N ha(-1) in above-ground biomass amounting to 1208 kg N fixed
ha(-1) over 12 years. Harvest of 12-year old trees removed
approximately 91% of standing aboveground biomass from the site as
timber and fuel wood. The resulting net N balance was +151 kg N ha(-1)
derived from remaining leaves, twigs, standing litter, and +562 kg N
ha(-1) when tree roots were included in the calculation. The fast
growing A. mangium appears to be a viable fallow option for managing N
in these systems. However, other nutrients have to be replaced by using
part of the timber and fuel wood sales to compensate for large amounts
of nutrient removed in order for the system to be sustainable.
UT WOS:000287500200005
SN 0167-4366
doi 10.1007/s10457-010-9309-8

Publication type J
Title Estimates of strain additive genetic, heterosis and reciprocal effects
for male proportion in Nile tilapia, Oreochromis niloticus L.
Author/s Lozano, C Gjerde, B Bentsen, HB Dionisio, EE Rye, M
Journal source AQUACULTURE
Vol 312
Issue 1-4
Start page 32
End page 42
Publication year 2011
Times cited 0
Abstract Data from the GIFT complete diallel cross with eight strains of Nile
tilapia reared at seven different grow out environments were analyzed
to evaluate the feasibility of using breeders from the best performing
strains or strain combinations to increase male proportion in the
population. Of the three strain genetic by test environment interaction
effects evaluated, i.e., strain additive, strain reciprocal and strain
heterosis, only the latter was found to be significantly different from
zero (P < 0.05). However, it was difficult to see any trend with
respect to the ranking of the strain total heterosis estimates across
different environments, a prerequisite for a commercial utilization of
these heterosis effects in a breeding program. Of those effects found
to have a significant effect (P < 0.05) on male proportion, the
environment effect accounted for 0.12%, the batch effect for 0.23%, the
strain additive genetic effect for 0.06%, the strain reciprocal effect
for 0.25% and the strain total heterosis effect for 0.42% of the total
variation in male proportion. The largest difference between two
strains was 13.3 +/- 4.6 percentage points (P < 0.001) for the additive
genetic effect, 12.0 +/- 2.2 percentage points (P < 0.001) for the
reciprocal effect and 5.7 +/- 2.2 percentage points (P < 0.01) for the
general heterosis effect. Average heterosis for male proportion was not
significantly different from zero (1.8 +/- 1.2 percentage points; P >
0.05), however for some strain crosses the total strain heterosis
effect was substantial with 19.7 +/- 4.4 percentage points (P < 0.001)
as the largest difference between two strain crosses. The strain
additive effect explained only 3%, the strain reciprocal effect 25% and
the strain total heterosis effect 59% of the variation in total
performance (strain additive + strain reciprocal + strain total
heterosis) in male proportion. However, most of the variation in total
heterosis was due to the specific heterosis effect which explained a
large proportion (53%) of the variation in total performance in male
proportion among the crosses, and thus is more important than any of
the other studied strain genetic effects; i.e. the strain additive,
reciprocal and general heterosis effects. Therefore to maximize gain in
male proportion the strain cross or crosses with highest total
performance should be chosen. It can be concluded that genetic
improvement of male proportion through the use of breeders from the
strain and strain crosses with highest male proportion in this study
will have an insufficient impact for the immediate commercial
applications under the tested farming conditions in the Philippines.(C)
2011 Elsevier B.V. All rights reserved.
UT WOS:000287836100005
SN 0044-8486
doi 10.1016/j.aquaculture.2010.12.037

Publication type J
Title Diet development and evaluation for juvenile abalone, Haliotis asinina
Linne: Lipid and essential fatty acid levels
Author/s Bautista-Teruel, MN Koshio, SS Ishikawa, M
Journal source AQUACULTURE
Vol 312
Issue 1-4
Start page 172
End page 179
Publication year 2011
Times cited 0
Abstract Experiments on diet development and evaluation for juvenile abalone,
Haliotis asinina focusing on lipid and essential fatty acid (EFA)
levels were conducted. Six isonitrogenous diets were formulated in
Experiment 1 (E1)) to contain 27% protein with lipid levels at 0, 2, 4,
6, 8, and 10%. Experiment 2 (E2) (EFA levels), used the optimum lipid
level (3.59%) in E1 with EFA supplementation of 0.0, 0.2, 0.4, 0.8, and
1.6%. Abalone juveniles [mean initial weight and shell length of 0.60
+/- 0.07 g and 14.70 +/- 0.12 mm (E1], [0.60 +/- 0.16 g and 15.30 +/-
0.73 mm (E2)] respectively, were fed these diets at 2-5% body weight in
3 replicates. Feeding trials in 90 days/experiment evaluated growth,
survival, feed conversion ratio (FCR) and fatty acid composition in
abalone tissues. Results showed significantly higher growth rates
(ANOVA P < 0.05) with abalone fed diets with lipid levels of 2.2%,
3.6%, and 6.1% compared with those containing lipid levels of 7.6% and
9.8%. Abalone fed the lipid-free diet showed significantly the lowest
growth rate among treatments. Break point analysis as a function of
growth, showed optimum lipid requirement at 3.59%. Survival was high at
95-99% in both experiments. FCR values for D3 and D4 were significantly
better compared to D2, D5 and D6 (E1)) while no significant differences
were found for D2-D6 for E2. Abalone body lipid increased with
corresponding increase in dietary lipid. Addition of 18:2n-6, 18:3n-3,
and n-3 HUFA showed significant improvement in weight gains up to 1.6%
supplementation. Fatty acid composition of the lipid samples reflected
those of the diets. Total lipid of abalone fed the lipid-free diet
showed higher monoenes. Addition of EFA resulted in an increase in both
n-3 and n-6 fatty acids. Lipid incorporation at 3.6% using a 1:1 ratio
of CLO and SBO with EFA supplementation (1.6%) is best in juvenile
abalone diet formulation. (C) 2011 ensevier B.V. All rights reserved.
UT WOS:000287836100021
SN 0044-8486
doi 10.1016/j.aquaculture.2011.01.004

Publication type J
Title Stable pi-pi dependent electron conduction band of TPP[M(Pc)L-2](2)
molecular conductors (TPP = tetraphenylphosphonium; M = Co, Fe; Pc =
phthalocyaninato; L = CN, Cl, Br)
Author/s Yu, DECMatsuda, M Tajima, H Naito, T Inabe, T
Vol 40
Issue 10
Start page 2283
End page 2288
Publication year 2011
Times cited 0
Abstract The partially-oxidized TPP[M(Pc)L-2](2) molecular conductors exhibit
variable electronic and magnetic transport bulk materials properties
due to central metal and axial ligand molecular modifications. The
controllable electrical conductivity and giant negative
magnetoresistance can be mainly attributable to the varying ligand
field energy and physical bulkiness of the axial ligands which cause
modulation in the intra-molecular pi-d (Pc-M) and inter-molecular pi-pi
(Pc-Pc) interactions in the TPP[M(Pc)L-2](2) system, respectively.
Characterization of the electronic conduction band utilizing
one-dimensional (1-D) tight-binding approximation from infrared
reflectance and thermoelectric power profile reveal consistent band
widths of 0.43 eV-0.62 eV for the Co series (L = Br < Cl < CN) and
0.44-0.56 eV for the Fe series (L = Br < Cl < CN). The fixed band width
suggests that stable electron conduction bands (transport pathway) can
be constructed which can withstand the molecular pi-d interaction
modifications that severely alter the bulk electronic and magnetic
materials properties of the TPP[M(Pc)L-2](2) molecular conductors.
UT WOS:000287665000029
SN 1477-9226
doi 10.1039/c0dt01054e

Publication type J
Title Rapid and high-precision marker assisted backcrossing to introgress the
SUB1 QTL into BR11, the rainfed lowland rice mega variety of Bangladesh
Author/s Iftekharuddaula, KM Newaz, MA Salam, MA Ahmed, HU Mahbub, MAA Septiningsih, EM Collard, BCY Sanchez, DL Pamplona, AM Mackill, DJ
Journal source EUPHYTICA
Vol 178
Issue 1
Start page 83
End page 97
Publication year 2011
Times cited 0
Abstract Flooding is one of the major hazards of rice production for the rainfed
lowland rice ecosystem, and tolerant cultivars are urgently needed to
help protect farmers from submergence damage. A quick and efficient
strategy was implemented to introgress SUB1, a major QTL for
submergence tolerance, into a rainfed lowland mega variety BR11 of
Bangladesh by only two backcrosses and one selfing generation. In
marker-assisted backcrossing (MABC), one tightly-linked simple sequence
repeat (SSR) and two gene-based markers, four flanking SSR and 116
background SSR markers were used for foreground, recombinant and
background selection, respectively, in backcrosses between a SUB1 donor
IR40931-33-1-3-2 and BR11. BR11-Sub1, identified in a BC2F2 plant,
possessed BR11 type SSR alleles on all fragments analyzed except the
SUB1 QTL. The introgression size in BR11-Sub1 was 800 Kb indicating
approximately 99.8% identity to BR11. BR11-Sub1 along with other
introgression lines showed submergence tolerance similar to the
tolerant parent. Yield, yield-component parameters and grain
physico-chemical properties showed successful recovery of the BR11
traits in BR11-Sub1, with yield potential ranging from 5.2 to 5.6 t/ha,
not significantly different from the recurrent parent mega variety
BR11. Producing a large number (similar to 1000) of backcross F-1
plants was considered essential to achieve recombination on both sides
of the gene, limiting linkage drag with only two backcrosses. A large
number of background markers ensured proper recovery of the recurrent
parent genome in the BC2F2 generation. The study demonstrates a rapid
and highly precise strategy to introgress a major QTL by BC2F2
generation into a modern rice variety using an unadapted donor. The
variety can replace BR11 on more than 2 million of ha in Bangladesh and
provide major increases in rice production.
UT WOS:000287456800007
SN 0014-2336
doi 10.1007/s10681-010-0272-2

Publication type J
Title Resistance to rice sheath blight (Rhizoctonia solani Kuhn)
[(teleomorph: Thanatephorus cucumeris (Abstract Frank) Donk.] disease:
current status and perspectives
Author/s Srinivasachary Willocquet, L Savary, S
Journal source EUPHYTICA
Vol 178
Issue 1
Start page 1
End page 22
Publication year 2011
Times cited 0
Abstract Sheath blight (ShB) disease, caused by Rhizoctonia solani, is an
economically important rice disease worldwide, especially in intensive
production systems. Several studies have been conducted to identify
sources for ShB resistance in different species of rice, including
local accessions and landraces. To date, none of the genotypes screened
are immune to ShB, although variation in levels of resistance have been
reported. Several quantitative trait loci (QTL) for ShB resistance have
been identified using mapping populations derived from indica or
japonica rice. A total of 33 QTL associated with ShB resistance located
on all 12 rice chromosomes have been reported, with ten of these
co-localizing with QTL for morphological attributes, especially plant
height, or for heading date. Sixteen QTL, from the same or differing
genetic backgrounds, have been mapped at least twice. Of these, nine
QTL were independent of morphological traits and heading date. We
hypothesize that two main, distinct, mechanisms contribute to ShB
resistance: physiological resistance and disease escape. Strategies to
improve our understanding of the genetics of resistance to ShB are
UT WOS:000287456800001
SN 0014-2336
doi 10.1007/s10681-010-0296-7

Publication type J
Title The Intrinsic Features of the Specific Heat at Half-Filled Landau
Levels of Two-Dimensional Electron Systems
Author/s Villagonzalo, C Gammag, R
Vol 163
Issue 1-2
Start page 43
End page 52
Publication year 2011
Times cited 0
Abstract The specific heat capacity of a two-dimensional electron gas is derived
for two types of the density of states, namely, the Dirac delta
function spectrum and that based on a Gaussian function. For the first
time, a closed form expression of the specific heat for each case is
obtained at half-filling. When the chemical potential is
temperature-independent, the temperature is calculated at which the
specific heat is a maximum. Here the effects of the broadening of the
Landau levels are distinguished from those of the different filling
factors. In general, the results derived herein hold for any
thermodynamic system having similar resonant states.
UT WOS:000287757900005
SN 0022-2291
doi 10.1007/s10909-010-0259-3

Publication type J
Title Spatio-temporal deviations in fluid flow resulting from particle-fluid
Author/s Valenzuela, JF Monterola, C
Publication year 2011
Times cited 0
Abstract We characterize the influence of the presence of suspended particles on
a fluid undergoing convection and find that it leads to deviations in
both the fluid speed and temperature. The spatio-temporal deviations of
the profiles for both fields are persistent in several well-defined
regions of the fluid. We find these variations to be robust and to be
exhibited by different temperature profiles, although the strength of
the deviations depends on the amount of time required by the suspension
to reach a steady state. The primary effect of the presence of the
particles is to weaken the fluid convective strength and heat flux, as
well as to change the convection’s spatial characteristics. The results
quantify the degree to which the physical presence and motion of
particles in a suspension affect its flow dynamics, a case that is
typically neglected in most modeling protocols.
UT WOS:000287802800042
SN 1742-5468
doi 10.1088/1742-5468/2011/02/P02038

Publication type J
Title Efficacy and safety of belimumab in patients with active systemic lupus
erythematosus: a randomised, placebo-controlled, phase 3 trial
Author/s Navarra, SV Guzman, RM Gallacher, AE Hall, S Levy, RA Jimenez, RE Li, EKM Thomas, M Kim, HY Leon, MGTanasescu, C Nasonov, E Lan, JL Pineda, L Zhong, ZJ Freimuth, W Petri, MA
Journal source LANCET
Vol 377
Issue 9767
Start page 721
End page 731
Publication year 2011
Times cited 4
Abstract Background Systemic lupus erythematosus is a heterogeneous autoimmune
disease that is associated with B-cell hyperactivity, autoantibodies,
and increased concentrations of B-lymphocyte stimulator (BLyS). The
efficacy and safety of the fully human monoclonal antibody belimumab
(BLyS-specific inhibitor) was assessed in patients with active systemic
lupus erythematosus.
Methods Patients (aged >= 18 years) who were seropositive with scores
of at least 6 on the Safety of Estrogens in Lupus Erythematosus
National Assessment Systemic Lupus Erythematosus Disease Activity Index
(SELENA-SLEDAI) were enrolled in a multicentre phase 3 study, which was
done in Latin America, Asia-Pacific, and eastern Europe. Patients were
randomly assigned by use of a central interactive voice response system
in a 1:1:1 ratio to belimumab 1 mg/kg or 10 mg/kg, or placebo by
intravenous infusion in 1 h on days 0, 14, and 28, and then every 28
days until 48 weeks, with standard of care. Patients, investigators,
study coordinators, and sponsors were masked to treatment assignment.
Primary efficacy endpoint was improvement in the Systemic Lupus
Erythematosus Responder Index (SRI) at week 52 (reduction >= 4 points
in SELENA-SLEDAI score; no new British Isles Lupus Assessment Group
[BILAG] A organ domain score and no more than 1 new B organ domain
score; and no worsening [<0.3 increase] in Physician’s Global
Assessment [PGA] score) versus baseline. Method of analysis was by
modified intention to treat. This trial is registered with
ClinicalTrials.gov, number NCT00424476.
Findings 867 patients were randomly assigned to belimumab 1 mg/kg
(n=289) or 10 mg/kg (n=290), or placebo (n=288). 865 were treated and
analysed in the belimumab (1 mg/kg, n=288; 10 mg/kg, n=290) and placebo
groups (n=287). Significantly higher SRI rates were noted with
belimumab 1 mg/kg (148 [51%], odds ratio 1.55 [95% CI 1.10-2.19];
p=0.0129) and 10 mg/kg (167 [58%], 1.83 [1.30-2.59]; p=0.0006) than
with placebo (125 [44%]) at week 52. More patients had their
SELENA-SLEDAI score reduced by at least 4 points during 52 weeks with
belimumab 1 mg/kg (153 [53%], 1.51 [1.07-2.14]; p=0.0189) and 10 mg/kg
(169 [58%], 1.71 [1.21-2.41]; p=0.0024) than with placebo (132 [46%]).
More patients given belimumab 1 mg/kg (226 [78%], 1.38 [0.93-2.04];
p=0.1064) and 10 mg/kg (236 [81%], 1.62 [1.09-2.42]; p=0.0181) had no
new BILAG A or no more than 1 new B flare than did those in the placebo
group (210 [73%]). No worsening in PGA score was noted in more patients
with belimumab 1 mg/kg (227 [79%], 1.68 [1.15-2.47]; p=0.0078) and 10
mg/kg (231 [80%], 1.74 [1.18-2.55]; p=0.0048) than with placebo (199
[69%]). Rates of adverse events were similar in the groups given
belimumab 1 mg/kg and 10 mg/kg, and placebo: serious infection was
reported in 22 (8%), 13 (4%), and 17 (6%) patients, respectively, and
severe or serious hypersensitivity reactions on an infusion day were
reported in two (<1%), two (<1%), and no patients, respectively. No
malignant diseases were reported.
Interpretation Belimumab has the potential to be the first targeted
biological treatment that is approved specifically for systemic lupus
erythematosus, providing a new option for the management of this
important prototypic autoimmune disease.
UT WOS:000287946000029
SN 0140-6736
doi 10.1016/S0140-6736(10)61354-2

Publication type J
Title Health in Southeast Asia 5 Human resources for health in southeast
Asia: shortages, distributional challenges, and international trade in
health services
Author/s Kanchanachitra, C Lindelow, MJ ohnston, T Hanvoravongchai, P Lorenzo, FM Nguyen, LH Wilopo, SA dela Rosa, JF
Journal source LANCET
Vol 377
Issue 9767
Start page 769
End page 781
Publication year 2011
Times cited 1
Abstract In this paper, we address the issues of shortage and maldistribution of
health personnel in southeast Asia in the context of the international
trade in health services. Although there is no shortage of health
workers in the region overall, when analysed separately, five
low-income countries have some deficit. All countries in southeast Asia
face problems of maldistribution of health workers, and rural areas are
often understaffed. Despite a high capacity for medical and nursing
training in both public and private facilities, there is weak
coordination between production of health workers and capacity for
employment. Regional experiences and policy responses to address these
challenges can be used to inform future policy in the region and
elsewhere. A distinctive feature of southeast Asia is its engagement in
international trade in health services. Singapore and Malaysia import
health workers to meet domestic demand and to provide services to
international patients. Thailand attracts many foreign patients for
health services. This situation has resulted in the so-called brain
drain of highly specialised staff from public medical schools to the
private hospitals. The Philippines and Indonesia are the main exporters
of doctors and nurses in the region. Agreements about mutual
recognition of professional qualifications for three groups of health
workers under the Association of Southeast Asian Nations Framework
Agreement on Services could result in increased movement within the
region in the future. To ensure that vital human resources for health
are available to meet the needs of the populations that they serve,
migration management and retention strategies need to be integrated
into ongoing efforts to strengthen health systems in southeast Asia.
There is also a need for improved dialogue between the health and trade
sectors on how to balance economic opportunities associated with trade
in health services with domestic health needs and equity issues.
UT WOS:000287946000034
SN 0140-6736
doi 10.1016/S0140-6736(10)62035-1

Publication type J
Title A set of near-isogenic lines of Indica-type rice variety CO 39 as
differential varieties for blast resistance
Author/s Telebanco-Yanoria, MJ Koide, Y Fukuta, Y Imbe, T Tsunematsu, H Kato, H Ebron, LA Thi, MNN Kobayashi, N
Vol 27
Issue 3
Start page 357
End page 373
Publication year 2011
Times cited 0
Abstract Twenty-seven near-isogenic lines (NILs) with the genetic background of
a blast-susceptible variety, CO 39, were developed by repeated
backcrossing as a first set of a large number of differential varieties
(DVs) with Indica-type genetic background. The NILs included 14
resistance genes-Pish, Pib, Piz-5, Piz-t, Pi5(t), Pik-s, Pik, Pik-h,
Pik-m, Pik-p, Pi1, Pi7(t), Pita, and Pita-2-derived from 26 donor
varieties. The reaction patterns of NILs against 20 standard isolates
from the Philippines were similar to those of blast monogenic lines
with the same resistance gene, except for those against two isolates
that are avirulent to Pia in the genetic background of CO 39. A
genome-wide DNA marker survey revealed that chromosome segments were
introgressed in the regions where each resistance gene was previously
mapped and most of the other chromosome regions in each NIL were CO 39
type. Segregation analysis of resistance and co-segregation analysis
between resistance and DNA markers using F3 populations derived from
the crosses between each NIL and the recurrent parent, CO 39, revealed
a single-gene control of resistance and association between resistance
and target introgressed segments. The morphological characters of each
NIL were almost the same as those of the recurrent parent except for
some lines, suggesting that these NILs can be used even under tropical
conditions where Japonica-type DVs are not suitable for cropping. Thus,
these NILs are useful not only as genetic tools for blast resistance
study but also as sources of genes for breeding of Indica-type rice
UT WOS:000287754700008
SN 1380-3743
doi 10.1007/s11032-010-9437-x

Publication type J
Title Apixaban in Patients with Atrial Fibrillation
Author/s Connolly, SJ Eikelboom, J Joyner, C Diener, H CHart, R Golitsyn, S Flaker, G Avezum, A Hohnloser, SH Diaz, R Talajic, M Zhu, J Pais, P Budaj, A Parkhomenko, A Jansky, P Commerford, P Tan, RS Sim, KH Lewis, BS Van Mieghem, W Lip, GYH Kim, JH Lanas-Zanetti, F Gonzalez-Hermosillo, A Dans, AL Munawar, M O’Donnell, M Lawrence, J Lewis, G Afzal, R Yusuf, S
Vol 364
Issue 9
Start page 806
End page 817
Publication year 2011
Times cited 3
Vitamin K antagonists have been shown to prevent stroke in patients
with atrial fibrillation. However, many patients are not suitable
candidates for or are unwilling to receive vitamin K antagonist
therapy, and these patients have a high risk of stroke. Apixaban, a
novel factor Xa inhibitor, may be an alternative treatment for such
In a double-blind study, we randomly assigned 5599 patients with atrial
fibrillation who were at increased risk for stroke and for whom vitamin
K antagonist therapy was unsuitable to receive apixaban (at a dose of 5
mg twice daily) or aspirin (81 to 324 mg per day), to determine whether
apixaban was superior. The mean follow up period was 1.1 years. The
primary outcome was the occurrence of stroke or systemic embolism.
Before enrollment, 40% of the patients had used a vitamin K antagonist.
The data and safety monitoring board recommended early termination of
the study because of a clear benefit in favor of apixaban. There were
51 primary outcome events (1.6% per year) among patients assigned to
apixaban and 113 (3.7% per year) among those assigned to aspirin
(hazard ratio with apixaban, 0.45; 95% confidence interval [CI], 0.32
to 0.62; P<0.001). The rates of death were 3.5% per year in the
apixaban group and 4.4% per year in the aspirin group (hazard ratio,
0.79; 95% CI, 0.62 to 1.02; P = 0.07). There were 44 cases of major
bleeding (1.4% per year) in the apixaban group and 39 (1.2% per year)
in the aspirin group (hazard ratio with apixaban, 1.13; 95% CI, 0.74 to
1.75; P = 0.57); there were 11 cases of intracranial bleeding with
apixaban and 13 with aspirin. The risk of a first hospitalization for
cardiovascular causes was reduced with apixaban as compared with
aspirin (12.6% per year vs. 15.9% per year, P<0.001). The treatment
effects were consistent among important subgroups.
In patients with atrial fibrillation for whom vitamin K antagonist
therapy was unsuitable, apixaban reduced the risk of stroke or systemic
embolism without significantly increasing the risk of major bleeding or
intracranial hemorrhage.
UT WOS:000287928400006
SN 0028-4793
doi 10.1056/NEJMoa1007432

Publication type J
Title Emerging Asia: Decoupling or Recoupling
Author/s Kim, S Lee, JW Park, CY
Journal source WORLD ECONOMY
Vol 34
Issue 1
Start page 23
End page 53
Publication year 2011
Times cited 0
Abstract In this paper, we investigate the degree of real economic
interdependence between emerging East Asian and major industrial
countries to shed light on the heated debate over the ‘decoupling’ of
emerging East Asia. We first document the evolution of macroeconomic
interdependence for emerging East Asian economies through changing
trade and financial linkages at both the regional and global levels.
Then, by employing a panel vector autoregression (VAR) model, we
estimate the degree of real economic interdependence before and after
the 1997/98 Asian financial crisis. Empirical findings show that real
economic interdependence increased significantly in the post-crisis
period, suggesting ‘recoupling’, rather than decoupling, in recent
years. Output shocks from major industrial countries have a significant
positive effect on emerging East Asian economies. More interestingly,
the reverse is also true. Output shocks from emerging East Asia (and
China) have a significant positive effect on output in major industrial
countries. The result suggests that macroeconomic interdependence
between emerging East Asia and industrial countries have become
‘bi-directional’, defying the traditional notion of the ‘North-South
relationship’ as one of ‘uni-directional’ dependence.
UT WOS:000286401300002
SN 0378-5920
doi 10.1111/j.1467-9701.2010.01280.x

Publication type J
Title Estimation of site amplification and S-wave velocity profiles in
metropolitan Manila, the Philippines, from earthquake ground motion
Author/s Yamanaka, H Ohtawara, K Grutas, R Tiglao, RB Lasala, M Narag, IC Bautista, BC
Vol 42
Issue 1
Start page 69
End page 79
Publication year 2011
Times cited 0
Abstract In this study, empirical site amplifications and S-wave velocity
profiles for shallow and deep soils are estimated using earthquake
ground motion records in metropolitan Manila, the Philippines. We first
apply a spectral inversion technique to the earthquake records to
estimate effects of source, path, and local site amplification. The
earthquake data used were obtained during 36 moderate earthquakes at 10
strong-motion stations of an earthquake observation network in Manila.
The estimated Q value of the propagation path is modelled as
54.6f(1.1). Most of the source spectra can be approximated with the
omega-square model. The site amplifications show characteristic
features according to surface geological conditions. The amplifications
at the sites in the coastal lowland and Marikina Valley shows
predominant peaks at frequencies from 1 to 5 Hz, while those in the
central plateau are characterised by no dominant peaks. These site
amplifications are inverted to subsurface S-wave velocity. We, next,
discuss the relationship between the amplifications and average S-wave
velocity in the top 30 m of the S-wave velocity profiles. The
amplifications at low frequencies are well correlated with the averaged
S-wave velocity. However, high-frequency amplifications cannot be
sufficiently explained by the averaged S-wave velocity in the top 30 m.
They are correlated more with the average of S-wave velocity over
depths less than 30 m.
UT WOS:000287707700008
SN 0812-3985
doi 10.1071/EG11003

Publication type J
Title Relationship of Porcine Plasma Free Insulin-like Growth Factor 1
(IGF-1) with the Growth Performance and Scrotal Length of Landrace Boars
Author/s Sangel, PP Roxas, NP
Vol 13
Issue 1
Start page 51
End page 56
Publication year 2011
Times cited 0
Abstract Insulin-like Growth Factor 1 (IGF-1) is a 7.6 kDa, 70 amino acid
residue peptide hormone that has been shown to be involved in the
metabolic regulation of growth and reproduction in livestock. The
present study was undertaken to quantify the concentrations of plasma
free IGF-1 in growing Landrace boars and determine whether the plasma
free IGF-1 concentration can be used as a selection criterion for
growth. A total of fourteen (n = 14) Landrace boars were bled, weighed
and monitored for ADG, backfat thickness and scrotal length at 15 and
24 weeks of age. Plasma samples were extracted from the blood and
plasma free IGF-1 concentrations were measured using the DSL 10-9400
Active free IGF-1 Enzyme-Linked Immunosorbent (ELISA) kit. Experimental
Landrace boars data on live weight, ADG, backfat thickness and scrotal
length were correlated with their levels of plasma free IGF-1. This
study has demonstrated a significant decrease (P = 0.0001) in the
circulating plasma free IGF-1 concentration of Landrace boars from 15
to 24 weeks of age. Furthermore, correlation of plasma free IGF-1
concentration with growth traits showed a positive association with ADO
(r = 0.726), while negative associations were established with backfat
thickness (r = -0.412), scrotal length (r= -0.700) and live weight (r=
-0.579). Results of this study suggest that circulating plasma free
IGF-1 is related to leaner body composition in swine. (C) 2011 Friends
Science Publishers
UT WOS:000287722400008
SN 1560-8530

Publication type J
Title Dissecting Genetic Networks Underlying Complex Phenotypes: The
Theoretical Framework
Author/s Zhang, F Zhai, HQ Paterson, AH Xu, JL Gao, YM Zheng, TQ Wu, RL Fu, BY Ali, J Li, ZK
Journal source PLOS ONE
Vol 6
Issue 1
Publication year 2011
Times cited 0
Abstract Great progress has been made in genetic dissection of quantitative
trait variation during the past two decades, but many studies still
reveal only a small fraction of quantitative trait loci (QTLs), and
epistasis remains elusive. We integrate contemporary knowledge of
signal transduction pathways with principles of quantitative and
population genetics to characterize genetic networks underlying complex
traits, using a model founded upon one-way functional dependency of
downstream genes on upstream regulators (the principle of hierarchy)
and mutual functional dependency among related genes (functional
genetic units, FGU). Both simulated and real data suggest that
complementary epistasis contributes greatly to quantitative trait
variation, and obscures the phenotypic effects of many ‘downstream’
loci in pathways. The mathematical relationships between the main
effects and epistatic effects of genes acting at different levels of
signaling pathways were established using the quantitative and
population genetic parameters. Both loss of function and “co-adapted”
gene complexes formed by multiple alleles with differentiated functions
(effects) are predicted to be frequent types of allelic diversity at
loci that contribute to the genetic variation of complex traits in
populations. Downstream FGUs appear to be more vulnerable to loss of
function than their upstream regulators, but this vulnerability is
apparently compensated by different FGUs of similar functions. Other
predictions from the model may account for puzzling results regarding
responses to selection, genotype by environment interaction, and the
genetic basis of heterosis.
UT WOS:000286522200003
SN 1932-6203
doi 10.1371/journal.pone.0014541

Publication type J
Title Frequency of Cardiac Events at Four Years Among Initially Asymptomatic
Filipinos with the Brugada Type 1 Electrocardiographic Pattern
Author/s Domingo, GG Jocson, G Dans, A
Vol 107
Issue 5
Start page 714
End page 716
Publication year 2011
Times cited 0
Abstract Brugada type 1 electrocardiographic (ECG) pattern occurs in 0.2% of
Filipinos. A knowledge gap exists on the natural course of asymptomatic
patients with Brugada type 1 ECG pattern. Most studies that reported
cohort event rates were taken from hospitals or referral centers. This
is the first cohort from an entire country where the subjects were
selected randomly. The objective of this study was to describe the
frequency of cardiac events at 4 and 6 years of 7 patients with Brugada
type 1 ECG pattern of 3,907 patients previously screened from the
general population of the Philippines during the National Nutrition and
Health Survey. Personal interviews at year 4 using a structured
questionnaire were conducted by 1 of the investigators. Occurrences of
major (syncope, seizure, unexplained accidents, sudden death) and minor
events in subjects and their first- and second-degree relatives were
elicited. Six-year follow-up by text messaging was conducted to
ascertain vital status and occurrence of cardiac events. All 7 patients
with Brugada type 1 ECG pattern were men. Three of the 7 initially
asymptomatic subjects (43%, 95 confidence interval 6 to 80) developed a
major cardiac event by the fourth year. Those with events were younger
than those without events. All 7 were alive by the sixth year. No
additional events were noted between the fourth and sixth years. In
conclusion, cardiac events are considerable in initially asymptomatic
Filipinos with Brugada type 1 ECG pattern. (c) 2011 Elsevier Inc. All
rights reserved. (Am J Cardiol’2011;107:714-716)
UT WOS:000287837200013
SN 0002-9149
doi 10.1016/j.amjcard.2010.10.047

Publication type J
Title Middle Eocene low-paleolatitude radiolarian evidence for the Cabog
Formation, Central East Luzon, Philippine Mobile Belt
Author/s Ishida, K Suzuki, S Yumul, GP Dimalanta, CB
Vol 19
Issue 1
Start page 61
End page 70
Publication year 2011
Times cited 1
Abstract The Cabog Formation, newly established herein and exposed in central
East Luzon, Philippine Mobile Belt, is defined in age by the occurrence
of radiolarians. The radiolarian assemblage is correlative with the
middle Eocene and suggests a low paleolatitude affinity. The
correlation, sedimentary environment, and the tectonic significance are
discussed. The Cabog Formation is correlative with the distal part of
the middle-late Eocene Caraballo Formation, which is exposed in the
northeastern side of the Philippine Fault Zone. The sandstone
composition and radiolarian age suggest that the Cabog Formation
represents the first depositional stage in the early arc setting. The
northward migration of the formation is also estimated in relation with
the Philippine Sea Plate motion along the Older Philippine Fault from
the equatorial area. (C) 2010 International Association for Gondwana
Research. Published by Elsevier B.V. All rights reserved.
UT WOS:000286960100006
SN 1342-937X
doi 10.1016/j.gr.2010.05.010

Publication type J
Title Comparative analysis of exit interviews and direct clinical
observations in Pediatric Ambulatory Care Services in Afghanistan
Author/s Onishi, J Gupta, S Peters, DH
Vol 23
Issue 1
Start page 76
End page 82
Publication year 2011
Times cited 0
Abstract To assess the receiver operating curves (ROCs) for counseling in the
management of common childhood diseases comparing direct observations
with exit interviews.
Eight thousand six hundred and fifty-nine randomly selected new
outpatient consultations of sick children under 5 years were assessed
by observation using a standardized checklist and an exit interview
with their parent/guardian, taken between 2005 and 2007 from 948 health
facilities in Afghanistan. The observation checklist was used as a
‘gold standard’ for counseling provided.
Sensitivity, specificity and ROCs were estimated for five counseling
items, including explanations of: a working diagnosis; what to do at
home; possible adverse reactions to medicine; signs that require a
return to the health facility; and a time to return.
The prevalence of counseling items was relatively low (ranging from 8
to 80%), but generally increasing each year. Exit interviews had
relatively low levels of sensitivity for the counseling items, ranging
from 33 to 88%, with higher levels of specificity (ranging from 63 to
91%), whereas the ROCs ranged from 61 to 77%. Although ROCs varied
significantly from year to year (P < 0.002 for each item), there was
little difference based on the sex or type of the health provider.
Exit interviews did not provide reliable measurements of provider
performance compared with direct observations. Observations identified
low prevalence of counseling tasks though increasing over time. The
differences between observation and exit interviews identified
significant gaps in communication, suggesting that exit interviews are
of low accuracy and should not be used alone.
UT WOS:000286474000010
SN 1353-4505
doi 10.1093/intqhc/mzq074

Publication type J
Title Stability in a population model without random deaths by the Verhulst
Author/s Pinol, CMN Banzon, RS
Vol 390
Issue 7
Start page 1295
End page 1299
Publication year 2011
Times cited 0
Abstract A large amount of population models use the concept of a carrying
capacity. Simulated populations are bounded by invoking finite
resources through a survival probability, commonly referred to as the
Verhulst factor. The fact, however, that resources are not easily
accounted for in actual biological systems makes the carrying capacity
parameter ill-defined. Henceforth, we deem it essential to consider
cases for which the parameter is unnecessary. This work demonstrates
the possibility of Verhulst-free steady states using the Penna aging
model, with one semelparous birth per adult. Stable populations are
obtained by setting a mutation threshold that is higher than the
reproduction age. (C) 2010 Elsevier B.V. All rights reserved.
UT WOS:000287901400009
SN 0378-4371
doi 10.1016/j.physa.2010.11.046

Publication type J
Title Product design enhancement using apparent usability and affective
Author/s Seva, RR Gosiaco, KGT Santos, MCED Pangilinan, DML
Vol 42
Issue 3
Start page 511
End page 517
Publication year 2011
Times cited 0
Abstract In this study, apparent usability and affective quality were integrated
in a design framework called the Usability Perception and Emotion
Enhancement Model (UPEEM). The UPEEM was validated using structural
equation modeling (SEM). The methodology consists of four phases namely
product selection, attribute identification, design alternative
generation, and design alternative evaluation. The first stage involved
the selection of a product that highly involves the consumer. In the
attribute identification stage, design elements of the product were
identified. The possible values of these elements were also determined
for use in the experimentation process. Design of experiments was used
to identify how the attributes will be varied in the design alternative
stage and which of the attributes significantly contribute to affective
quality, apparent usability, and desirability in the design evaluation
stage. Results suggest that product attributes related to form are
relevant in eliciting intense affect and perception of usability in
mobile phones especially those directly related to functionality and
aesthetics. This study considered only four product attributes among so
many due to the constraints of the research design employed. Attributes
related to aesthetic perception of a product enhance apparent usability
such as those related to dimensional ratios. (C) 2010 Elsevier Ltd and
The Ergonomics Society. All rights reserved.
UT WOS:000286709900014
SN 0003-6870
doi 10.1016/j.apergo.2010.09.009

Publication type J
Title Analysis of inter-plant water integration with indirect integration
schemes through game theory approach: Pareto optimal solution with
Author/s Chew, IML Thillaivarrna, SL Tan, RR Foo, DCY
Vol 13
Issue 1
Start page 49
End page 62
Publication year 2011
Times cited 1
Abstract Fresh resources such as water can be conserved through effective
reuse/recycle among several industrial plants with inter-plant water
integration (IPWI) scheme. Two types of IPWI schemes exist, i.e. direct
and indirect integrations. This article focuses on the latter, where
the water networks are integrated indirectly through a centralised
utility hub (CUH). The CUH acts as a buffer to collect water from
different networks, where water is intercepted for further
reuse/recycle (regeneration) and/or for final environmental discharge.
A recent developed game theory approach is extended for the use of
indirect IPWI schemes in this study. Besides, intervention by an
eco-industrial park (EIP) authority is included in the analysis to
investigate the influence of incentive on the participation of water
network in the IPWI.
UT WOS:000286464000005
SN 1618-954X
doi 10.1007/s10098-010-0280-x

Publication type J
Title Adductor Myocutaneous Flap Coverage for Hip and Pelvic Disarticulations
of Sarcomas with Buttock Contamination
Author/s Marfori, ML Wang, EHM
Vol 469
Issue 1
Start page 257
End page 263
Publication year 2011
Times cited 0
Abstract Background Hip disarticulation and hemipelvectomy are alternatives to
limb-salvage procedures for patients with extensive tumors of the upper
thigh and buttocks. In cases when neither the conventional posterior
gluteus maximus flap nor the anterior quadriceps flap can be used
because of the location of the tumor, a medial adductor myocutaneous
flap may be an alternative.
Description of Technique The flap is outlined over the anteromedial
thigh. The distal extent is at the level of the adductor hiatus. The
common femoral vessels and nerve are traced, preserved, and protected.
The adductor muscles then are divided above their insertions on the
femur and preserved with the flap. En bloc removal of the tumor is
performed by either hip disarticulation or hemipelvectomy. The long
adductor myocutaneous flap is brought up laterally and proximally to
close the wound.
Patients and Methods We reviewed four patients who underwent a medial
adductor myocutaneous flap after either hip disarticulation or
hemipelvectomy. The medical records and radiographs were analyzed.
These patients were followed up for at least a year or until death.
Results Wide surgical margins were achieved in all four patients and
the flap remained viable, with no skin necrosis or flap breakdown. The
patients were able to sit on the flap, and one patient was able to wear
a prosthesis.
Conclusions In patients undergoing hip disarticulation or
hemipelvectomy where tumor infiltration or inadvertent contamination by
previous surgery will not allow the traditional posterior gluteus
maximus or anterior quadriceps flap, this unconventional medial
adductor myocutaneous flap is a feasible, technically simple option.
Level of Evidence Level IV therapeutic study. See Guidelines for
Authors for a complete description of levels of evidence.
UT WOS:000286938400036
SN 0009-921X
doi 10.1007/s11999-010-1467-5

Publication type J
Title Trade-off between benefit and harm is crucial in health screening
recommendations. Part I: General principles
Author/s Dans, LF Silvestre, MAA Dans, AL
Vol 64
Issue 3
Start page 231
End page 239
Publication year 2011
Times cited 0
Abstract Health screening is defined as the use of a test or a series of tests
to detect unrecognized health risks or preclinical disease in
apparently healthy populations to permit prevention and timely
intervention. A health screening strategy consists of the sequence of a
screening test, confirmatory test(s), and finally, treatment(s) for the
condition detected. The potential benefits of health screening are easy
to understand, but the huge potential for physical and psychological
harm is less well recognized. Thus, health screening should only be
recommended when five criteria are satisfied: (I) the burden of illness
should be high, (2) the tests for screening and confirmation should be
accurate, (3) early treatment (or prevention) must be more effective
than late treatment, (4) the test(s) and treatment(s) must be safe, and
(5) the cost of the screening strategy must be commensurate with
potential benefit. Direct evidence from screening trials is subject to
less bias. In some instances, indirect evidence may be acceptable,
e.g., when the condition screened for is a risk factor for a disease
rather than the disease itself. (C) 2011 Elsevier Inc. All rights
UT WOS:000286703900002
SN 0895-4356
doi 10.1016/j.jclinepi.2010.09.009

Publication type J
Title Trade-off between benefit and harm is crucial in health screening
recommendations. Part II: Evidence summaries
Author/s Silvestre, MAA Dans, LF Dans, AL
Vol 64
Issue 3
Start page 240
End page 249
Publication year 2011
Times cited 0
Abstract Evidence on the effectiveness of health screening strategies may be
direct (i.e., studies on screening vs. no screening) or indirect (i.e.,
studies that separately evaluate the screening test[s], the
confirmatory test, or the treatment). Critical trade-offs in the
balance between harm and benefit for many screening strategies mandate
that advocates of health screening adhere to the ethical precepts of
nonmaleficence, autonomy, confidentiality, and equity. In our first
article, we pointed out five prerequisites to justifying a health
screening program: (I) the burden of illness should be high, (2) the
screening and confirmatory tests should be accurate, (3) early
treatment (or prevention) must be more effective than late treatment,
(4) the tests and the treatment(s) must be safe, and (5) the cost of
the screening strategy must be commensurate with the potential benefit.
As can be gleaned from these criteria, recommendations on screening
must be tailored to specific populations. Recommendations in one
country, no matter how authoritative, cannot be generalized to apply to
all other countries. Although accuracy, effectiveness, and safety data
may be global (criteria 2-4), burden of illness and efficiency
(criteria 1 and 5) will always vary from country to country. Rather
than review various national guidelines, in this last article of our
two-part series, we present evidence summaries to illustrate health
screening. Our examples were selected to address special issues related
to four situations screening for cancer, risk factors for disease,
genetic disorders, and infectious diseases. (C) 2011 Elsevier Inc. All
rights reserved.
UT WOS:000286703900003
SN 0895-4356
doi 10.1016/j.jclinepi.2010.09.008

Publication type J
Title Clinical presentations and outcomes of Filipino juvenile systemic lupus
Author/s Gulay, CB Dans, LF
Vol 9
Publication year 2011
Times cited 0
Abstract Objective: Juvenile Systemic Lupus Erythematosus (SLE) varies by
location and ethnicity. This study describes the clinical, laboratory
profile and outcome of juvenile SLE seen at Philippine General Hospital
(PGH) from 2004-2008.
Method: Medical charts of all Filipino Juvenile SLE cases admitted at
PGH during the 5-year period were reviewed collecting demographic
profile, clinical and laboratory manifestations and treatment during
disease course.
Results: Seventy-eight cases of juvenile SLE were reviewed. There were
7 boys and 71 girls. The mean age at diagnosis was 14 years (SD 2.7)
with a range of 8-18 years. Fever (52.5%) and malar rash (41.0%) were
the most common features at disease onset. At the time of diagnosis,
the most common features were malar rash (65.3%), renal involvement
(62.8%) and photosensitivity (55.1%). Mucocutaneous (92.3%), renal
(71.7%) and hematologic (69.2%) involvement were the most common
features during the entire course of illness. Infection (34.5%) and
neurologic (19.0%) complications were observed most frequently.
Corticocosteroid treatment was given in most of the patients in the
form of prednisone (97.4%) and concomitant methylprednisolone
intravenous pulses (29.4%). Nine patients died during the study period.
The overall 5-year mortality rate was 11.5%. Infection (77.0%) was the
most frequent cause of death.
Conclusion: Malar rash was a common feature at disease onset and at
diagnosis among Filipinos with juvenile SLE. Throughout the disease
course, renal involvement occurs in 71.7% of patients. Infection was
the leading cause of complication and death. The clinical presentations
of Filipinos with juvenile SLE were similar to juvenile SLE in other
UT WOS:000287934100001
SN 1546-0096
doi 10.1186/1546-0096-9-7

Publication type J
Title Control of Common Bunt in Organic Wheat
Author/s Barroga-Matanguihan, J Murphy, KM Jones, SS
Journal source PLANT DISEASE
Vol 95
Issue 2
Start page 92
End page 103
Publication year 2011
Times cited 0
UT WOS:000286368700001
SN 0191-2917
doi 10.1094/PDIS-09-10-0620

Publication type J
Title A rare case of anterior thoracic myelomeningocele with scoliosis-case
report and review of the literature
Author/s Nathan, ST Puno, RM Paiso, JMS Kawakami, N
Journal source SPINE JOURNAL
Vol 11
Issue 2
Start page E16
End page E22
Publication year 2011
Times cited 0
Abstract BACKGROUND CONTEXT: Spinal deformities associated with spinal
dysraphism are a challenging problem. Myelomeningocele has been
reported in the lumbar spine. However, it is rare in the thoracic
PURPOSE: The purpose of the report was to heighten the awareness of the
rare presentation of the myelomeningocele in the thoracic spine and the
ability to correct the scoliosis without debulking the lesion.
STUDY DESIGN: This is a clinical case report and literature review.
METHODS: We report a 13-year-old girl presented with complaints of back
pain, difficulty in breathing, and easy fatigability. On examination,
she had a thoracolumbar scoliosis, weakness of the right ankle
dorsiflexors, and impaired sensation over the L5 dermatome of the right
lower limb. Radiographic examination revealed a 128 degrees
thoracolumbar scoliosis with congenital hemivertebra at T6-T9, block
vertebrae of T4 and T5, and intrathoracic myelomeningocele. She
underwent an anterior closing wedge osteotomy and posterior correction
of scoliosis without removal of the sac.
RESULTS: Four-year postoperative follow-up is uneventful. To date, our
patient is the first patient who had scoliosis correction surgery for
the rare presentation of a myelomeningocele in the thoracic spine
without removal of the sac.
CONCLUSIONS: To the best of our knowledge, this is the only case of
anterior thoracic myelomeningocele with scoliosis in the literature who
had undergone a surgical correction of the scoliosis with osteotomy
without removal of the sac. Although rare, these curves are well
amenable to surgical correction of scoliosis, thereby improving
endurance and functional lung capacity. (C) 2011 Elsevier Inc. All
rights reserved.
UT WOS:000286980400004
SN 1529-9430
doi 10.1016/j.spinee.2010.12.004

Publication type J
Title Feeding aggregation of Spratelloides delicatulus on giant clams’ gametes
Author/s Maboloc, EA Mingoa-Licuanan, SS
Journal source CORAL REEFS
Vol 30
Issue 1
Start page 167
End page 167
Publication year 2011
Times cited 0
UT WOS:000286940800019
SN 0722-4028
doi 10.1007/s00338-010-0703-5

Publication type J
Title Estimating modifiable coronary heart disease risk in multiple regions
of the world: the INTERHEART Modifiable Risk Score
Author/s McGorrian, C Yusuf, S Islam, S Jung, H Rangarajan, S Avezum, A Prabhakaran, D Almahmeed, W Rumboldt, ZBudaj, A Dans, AL Gerstein, HC Teo, K Anand, SS
Vol 32
Issue 5
Start page 581
End page U1400
Publication year 2011
Times cited 0
Abstract Aims Summating risk factor burden is a useful approach in the
assessment of cardiovascular risk among apparently healthy individuals.
We aimed to derive and validate a new score for myocardial infarction
(MI) risk using modifiable risk factors, derived from the INTERHEART
case-control study (n = 19 470).
Methods and results Multiple logistic regression was used to create the
INTERHEART Modifiable Risk Score (IHMRS). Internal validation was
performed using split-sample methods. External validation was performed
in an international prospective cohort study. A risk model including
apolipoproteins, smoking, second-hand smoke exposure, hypertension, and
diabetes was developed. Addition of further modifiable risk factors did
not improve score discrimination in an external cohort. Split-sample
validation studies showed an area under the receiver-operating
characteristic (ROC) curve c-statistic of 0.71 [95% confidence interval
(CI): 0.70, 0.72]. The IHMRS was positively associated with incident MI
in a large cohort of people at low risk for cardiovascular disease [12%
increase in MI risk (95% CI: 8, 16%) with a 1-point increase in score]
and showed appropriate discrimination in this cohort (ROC c-statistic
0.69, 95% CI: 0.64, 0.74). Results were consistent across ethnic groups
and geographic regions. A non-laboratory-based score is also supplied.
Conclusions Using multiple modifiable risk factors from the INTERHEART
case-control study, we have developed and validated a simple score for
MI risk which is applicable to an international population.
UT WOS:000288028600016
SN 0195-668X
doi 10.1093/eurheartj/ehq448

Publication type J
Title Infant-feeding patterns and cardiovascular risk factors in young
adulthood: data from five cohorts in low- and middle-income countries
Author/s Fall, CHD Borja, JB Osmond, C Richter, LB hargava, SK Martorell, R Stein, AD Barros, FC Victora, GC
Vol 40
Issue 1
Start page 47
End page 62
Publication year 2011
Times cited 2
Abstract Background Infant-feeding patterns may influence lifelong health. This
study tested the hypothesis that longer duration of breastfeeding and
later introduction of complementary foods in infancy are associated
with reduced adult cardiovascular risk.
Methods Data were pooled from 10 912 subjects in the age range of 15-41
years from five prospective birth-cohort studies in low-/middle-income
countries (Brazil, Guatemala, India, Philippines and South Africa).
Associations were examined between infant feeding (duration of
breastfeeding and age at introduction of complementary foods) and adult
blood pressure (Start page), plasma glucose concentration and adiposity
(skinfolds, waist circumference, percentage body fat and
overweight/obesity). Analyses were adjusted for maternal socio-economic
status, education, age, smoking, race and urban/rural residence and
infant birth weight.
Results There were no differences in outcomes between adults who were
ever breastfed compared with those who were never breastfed. Duration
of breastfeeding was not associated with adult diabetes prevalence or
adiposity. There were U-shaped associations between duration of
breastfeeding and systolic Start page and hypertension; however, these were
weak and inconsistent among the cohorts. Later introduction of
complementary foods was associated with lower adult adiposity. Body
mass index changed by -0.19kg/m(2) [95% confidence interval (CI) -0.37
to -0.01] and waist circumference by -0.45cm (95% CI -0.88 to -0.02)
per 3-month increase in age at introduction of complementary foods.
Conclusions There was no evidence that longer duration of breastfeeding
is protective against adult hypertension, diabetes or
overweight/adiposity in these low-/middle-income populations. Further
research is required to determine whether ‘exclusive’ breastfeeding may
be protective. Delaying complementary foods until 6 months, as
recommended by the World Health Organization, may reduce the risk of
adult overweight/adiposity, but the effect is likely to be small.
UT WOS:000288720900010
SN 0300-5771
doi 10.1093/ije/dyq155

Publication type J
Title How Quickly do Fragments of Coral “Self-Attach” after Transplantation?
Author/s Guest, JR Dizon, RM Edwards, AJ Franco, C Gomez, ED
Vol 19
Issue 2
Start page 234
End page 242
Publication year 2011
Times cited 0
Abstract Transplantation of coral fragments is seen as a potential method to
rapidly restore coral cover to areas of degraded reef; however,
considerable research is still needed to assess the effectiveness of
coral transplantation as a viable reef restoration tool. Initially,
during restoration efforts, coral transplants are attached
artificially. Self-attachment (i.e., growth of coral tissue onto the
substrate) provides a more secure and lasting bond, thus knowledge
about self-attachment times for corals is of importance to reef
restoration. While it is known that coral fragments may generate new
tissue and bond to substrata within a few weeks of transplantation,
surprisingly little is known about the speed of self-attachment for
most species. Two independent experiments were carried out to examine
the self-attachment times of 12 scleractinian and one non-scleractinian
coral species to a natural calcium carbonate substrate. The first
experiment examined times to self-attachment in 11 species of differing
morphologies from seven families over approximately 7 months, whereas
the second experiment examined three fast-attaching Acropora species
over approximately 1 month. In the first experiment, the branching
species Acropora muricata had a significantly faster self-attachment
time compared to all other species, while Echinopora lamellosa had the
slowest self-attachment time. For the second experiment, A. muricata
was significantly slower to self-attach than Acropora hyacinthus
(tabular) and Acropora digitifera (corymbose-digitate). The results
suggest that a combination of factors including growth rates, growth
form and life history may determine how quickly fragments of coral
species self-attach after fragmentation and transplantation.
UT WOS:000287932600011
SN 1061-2971
doi 10.1111/j.1526-100X.2009.00562.x

Publication type J
Title An alternative approach for quantifying climate regulation by ecosystems
Author/s West, PC Narisma, GT Barford, CC Kucharik, CJ Foley, JA
Vol 9
Issue 2
Start page 126
End page 133
Publication year 2011
Times cited 1
Abstract Ecosystems provide multiple benefits to people, including climate
regulation. Previous efforts to quantify this ecosystem service have
been either largely conceptual or based on complex atmospheric models.
Here we review previous research on this topic and propose a new and
simple analytical approach for estimating the physical regulation of
climate by ecosystems. The proposed metric estimates how land-cover
change affects the loading of heat and moisture into the atmosphere,
while also accounting for the relative contribution of wind-transported
heat and moisture. Although feedback dynamics between land, atmosphere
and oceans are not modeled, the metric compares well with previous
studies for several regions. We find that ecosystems have the strongest
influence on surface climatic conditions in the boreal and tropical
regions, where temperature and moisture changes could substantially
offset or magnify greenhouse-forced changes. This approach can be
extended to estimate the effects of changing land cover on local,
physical climate processes that are relevant to society.
UT WOS:000288058100018
SN 1540-9295
doi 10.1890/090015

Publication type J
Title Revisiting climate thresholds and ecosystem collapse
Author/s Mumby, PJ Iglesias-Prieto, R Hooten, AJ Sale, PF Hoegh-Guldberg, O Edwards, AJ Harvell, CD Gomez, ED Knowlton, N Hatziolos, ME Kyewalyanga, MS Muthiga, N
Vol 9
Issue 2
Start page 94
End page 96
Publication year 2011
Times cited 0
UT WOS:000288058100012
SN 1540-9295
doi 10.1890/11.WB.002

Publication type J
Title Topology-dependent entropic differences for chiral polypeptides in
Author/s Bernido, CC Carpio-Bernido, MV Aringa, HP
Journal source PHYSICS LETTERS A
Vol 375
Issue 9
Start page 1225
End page 1228
Publication year 2011
Times cited 0
Abstract The entropy of topological conformations of helical biopolymers in a
solvent is determined as a function of the chirality of winding.
Probability distributions are obtained by taking all possible winding
conformations of a polypeptide. The results show that between mirror
image distributions, there is a difference in entropy arising from a
net topological winding number and the interaction of a chiral solute
with its environment. This interaction is reflected in a drift
coefficient which varies from segment to segment along the length of a
biopolymer. (C) 2011 Elsevier B.V. All rights reserved.
UT WOS:000288051100002
SN 0375-9601
doi 10.1016/j.physleta.2011.01.030

Publication type J
Title Molecular detection of Edwardsiella tarda with gyrB gene isolated from
pirarucu, Arapaima gigas which is exhibited in an indoor private
commercial aquarium
Author/s Choresca, CH Gomez, DK Shin, SP Kim, JH Han, JE Jun, JW Park, SC
Vol 10
Issue 5
Start page 848
End page 850
Publication year 2011
Times cited 0
Abstract The pirarucu, Arapaima gigas, which was displayed in commercial
aquarium was found dead and was submitted for diagnostic examination.
Bacteria from different organs of the fish were characterized using
Vitek System (R) 2 and showed 98% probability to Edwardsiella tarda.
Polymerase chain reaction (PCR) result showed positive for E. tarda
gyrB gene. The 16S rRNA gene was identical and exhibited 99% sequence
similarity with the other known isolates of E. tarda available in the
GenBank. This paper reports the isolation and detection of E. tarda
with the gyrB gene in pirarucu, A. gigas, which was exhibited in an
indoor private commercial aquarium in Seoul, South Korea.
UT WOS:000287930800016
SN 1684-5315

Publication type J
Title Longitudinal changes in testosterone among men transitioning to
fatherhood in the Philippines
Author/s Gettler, LT Agustin, SS McDade, TW Kuzawa, CW
Vol 23
Issue 2
Start page 260
End page 260
Publication year 2011
Times cited 0
UT WOS:000287564200046
SN 1042-0533

Publication type J
Title Generation of Antibodies Against Rice stripe virus Proteins Based on
Recombinant Proteins and Synthetic Polypeptides
Author/s Lian, S Jonson, MG Cho, WK Choi, HS Je, YH Kim, KH
Vol 27
Issue 1
Start page 37
End page 43
Publication year 2011
Times cited 0
Abstract Rice stripe virus (RSV) is one of serious epidemic pathogens for rice
species grown in many Asian countries. Therefore, it is necessary to
produce a diagnostic detection kit applicable in fields for RSV
detection. In this study, RSV proteins that were derived from
recombinant proteins and synthetic polypeptides as antigens were
generated and were raised in rabbits for antiserum production. Among
seven proteins in RSV, genes that code for NCP and NS3 proteins were
cloned and subcloned into vector carrying His-tag protein and were
expressed in E. coli. Of two recombinant proteins, only anti-NCP
displayed stable hybridization signals in western blot analysis.
Alternately, synthetic RSV polypeptides for CP, NCP, NS3 and NSvc4 we
also generated and only antibodies against CP and NCP were very
effective to detect RSV in both RSV infected rice and weed plants.
However, antibodies against NS3 and NSvc4 showed weak specific bands as
well as strong non-specific background due to the difference of viral
proteins produced in the infected leaves. In summary, the antibodies
generated against RSV proteins produced in this study will be useful
for various assays such as for RSV diagnostic detection,
immunoprecipitation, protein purification, and western blot analysis.
UT WOS:000288040200007
SN 1598-2254
doi 10.5423/PPJ.2011.27.1.037

Publication type J
Title A wavelet Whittle estimator of generalized long-memory stochastic
Author/s Gonzaga, A Hauser, M
Vol 20
Issue 1
Start page 23
End page 48
Publication year 2011
Times cited 0
Abstract We consider a k-GARMA generalization of the long-memory stochastic
volatility model, discuss the properties of the model and propose a
wavelet-based Whittle estimator for its parameters. Its consistency is
shown. Monte Carlo experiments show that the small sample properties
are essentially indistinguishable from those of the Whittle estimator,
but are favorable with respect to a wavelet-based approximate maximum
likelihood estimator. An application is given for the Microsoft
Corporation stock, modeling the intraday seasonal patterns of its
realized volatility.
UT WOS:000286831600002
SN 1618-2510
doi 10.1007/s10260-010-0153-9

Publication type J
Title The Essential Cutset Number and Connectivity of the Join and
Composition of Graphs
Author/s Eballe, RG Canoy, SR
Vol 84
Start page 257
End page 263
Publication year 2011
Times cited 0
Abstract In a connected graph G a subset Y of V (G) is a cutset of G if the
removal of Y from G yields a disconnected subgraph. If Y is a cutset of
G such that Y cannot be reduced into a smaller cutset of G, then Y is
called an essential cutset of G. The essential cutset number of G,
denoted by ecs (G), is defined as the maximum cardinality of an
essential cutset of G. In this paper, the essential cutsets of the join
G + H and composition G[H] of two connected graphs G and H are
characterized. From the resulting characterizations, the essential
cutset numbers (as well as the vertex connectivity) of the
aforementioned graphs are computed. The essential cutset numbers and
connectivity of some known classes of graphs are also presented.
UT WOS:000287956500022
SN 0315-3681

Publication type J
Title Paediatric HIV and elimination of mother-to-child transmission of HIV
in the ASEAN region: a call to action
Author/s Ishikawa, N Ishigaki, K Ghidinelli, MN Ikeda, K Honda, M Miyamoto, H Kakimoto, K Oka, S
Vol 23
Issue 4
Start page 413
End page 416
Publication year 2011
Times cited 0
Abstract Recent achievements in scaling up paediatric antiretroviral therapy
(ART) have changed the life of children living with HIV, who now stay
healthy and live longer lives. However, as it becomes more of a chronic
infection, a range of new problems have begun to arise. These include
the disclosure of HIV serostatus to children, adherence to ART,
long-term toxicities of antiretroviral drugs and their sexual and
reproductive health, which are posing significant challenges to the
existing health systems caring for children with HIV with limited
resources, experiences and capacities. While intensified efforts and
actions to improve care and treatment for these children are needed, it
is crucial to accelerate the prevention of mother-to-child transmission
(PMTCT) of HIV, which is the main cause of paediatric HIV in the ASEAN
region so as to eliminate the fundamental cause of the problem. This
report argues that given over 70% of women have access to at least one
antenatal care visit in the region and acceptance of HIV testing after
receiving counselling on PMTCT could be as high as 90%, there is an
opportunity to strengthen PMTCT services and eventually eliminate new
paediatric HIV infections in the ASEAN countries.
UT WOS:000288118800003
SN 0954-0121
doi 10.1080/09540121.2010.516338

Publication type J
Title Permanent El Nino during the Pliocene warm period not supported by
coral evidence
Author/s Watanabe, T Suzuki, A Minobe, S Kawashima, T Kameo, K Minoshima, K Aguilar, YM Wani, R Kawahata, H Sowa, K Nagai, T Kase, T
Journal source NATURE
Vol 471
Issue 7337
Start page 209
End page 211
Publication year 2011
Times cited 0
Abstract The El Nino/Southern Oscillation (ENSO) system during the Pliocene warm
period (PWP; 3-5 million years ago) may have existed in a permanent El
Nino state with a sharply reduced zonal sea surface temperature (SST)
gradient in the equatorial Pacific Ocean(1). This suggests that during
the PWP, when global mean temperatures and atmospheric carbon dioxide
concentrations were similar to those projected for near-term climate
change(2), ENSO variability-and related global climate
teleconnections-could have been radically different from that today.
Yet, owing to a lack of observational evidence on seasonal and
interannual SST variability from crucial low-latitude sites, this
fundamental climate characteristic of the PWP remains
controversial(1,3-10). Here we show that permanent El Nino conditions
did not exist during the PWP. Our spectral analysis of the delta O-18
SST and salinity proxy, extracted from two 35-year, monthly resolved
PWP Porites corals in the Philippines, reveals variability that is
similar to present ENSO variation. Although our fossil corals cannot be
directly compared with modern ENSO records, two lines of evidence
suggest that Philippine corals are appropriate ENSO proxies. First,
delta O-18 anomalies from a nearby live Porites coral are correlated
with modern records of ENSO variability. Second, negative-delta O-18
events in the fossil corals closely resemble the decreases in delta
O-18 seen in the live coral during El Nino events. Prior research
advocating a permanent El Nino state may have been limited by the
coarse resolution of many SST proxies, whereas our coral-based analysis
identifies climate variability at the temporal scale required to
resolve ENSO structure firmly.
UT WOS:000288170200035
SN 0028-0836
doi 10.1038/nature09777

Publication type J
Title Effects of Recharge Wells and Flow Barriers on Seawater Intrusion
Author/s Luyun, R Momii, K Nakagawa, K
Journal source GROUND WATER
Vol 49
Issue 2
Start page 239
End page 249
Publication year 2011
Times cited 0
Abstract The installation of recharge wells and subsurface flow barriers are
among several strategies proposed to control seawater intrusion on
coastal groundwater systems. In this study, we performed
laboratory-scale experiments and numerical simulations to determine the
effects of the location and application of recharge wells, and of the
location and penetration depth of flow barriers, on controlling
seawater intrusion in unconfined coastal aquifers. We also compared the
experimental results with existing analytical solutions. Our results
showed that more effective saltwater repulsion is achieved when the
recharge water is injected at the toe of the saltwater wedge. Point
injection yields about the same repulsion compared with line injection
from a screened well for the same recharge rate. Results for flow
barriers showed that more effective saltwater repulsion is achieved
with deeper barrier penetration and with barriers located closer to the
coast. When the flow barrier is installed inland from the original toe
position however, saltwater intrusion increases with deeper barrier
penetration. Saltwater repulsion due to flow barrier installation was
found to be linearly related to horizontal barrier location and a
polynomial function of the barrier penetration depth.
UT WOS:000287584100018
SN 0017-467X
doi 10.1111/j.1745-6584.2010.00719.x

Publication type J
Title The Effect of Standardization on the Reliability of the Philippine
Board of Surgery Oral Examinations
Author/s Crisostomo, AC
Vol 68
Issue 2
Start page 138
End page 142
Publication year 2011
Times cited 0
Abstract BACKGROUND: Cognizant of potential problems with validity and
reliability, the Philippine Board of Surgery (PBS) undertook
standardization of its oral examination procedures. This retrospective
analytic study was conducted to determine and compare the reliability
of the Philippine Board of Surgery oral examinations before and after
METHODS: The records of oral examinations from June 29, 2003 to March
28, 2010 were reviewed and measures of reliability (intraclass
correlation coefficient and kappa agreement) were computed and compared
between the time periods before and after standardization and among
different case content modules administered. The proportion of passers
between time periods and different content areas were also compared.
RESULTS: All measures of interrater reliability (intraclass correlation
coefficient and kappa agreement) increased significantly overall and in
all content areas and regardless of examinee outcome. There was also a
trend to increased proportion of passers overall and significant
improvement in passing rate in 4 out of 6 content areas.
CONCLUSIONS: This study validates the role of standardization of the
content and scoring in improving the reliability of he oral
examination, which is crucial for high stakes certifying examinations.
(J Surg 68:138-142. (c) 2011 Association of Program Directors in
Surgery. Published by Elsevier Inc. All rights reserved.)
UT WOS:000288146100012
SN 1931-7204
doi 10.1016/j.jsurg.2010.09.013

Publication type J
Title Stercurensin Inhibits Nuclear Factor-kappa B-Dependent Inflammatory
Signals Through Attenuation of TAK1-TAB1 Complex Formation
Author/s Kim, YJ Kim, HC Ko, H Amor, EC Lee, JW Yang, HO
Vol 112
Issue 2
Start page 548
End page 558
Publication year 2011
Times cited 0
Abstract We identified a chalcone, 2′,4′-dihydroxy-6′-methoxy-3′-methylchalcone
(stercurensin), as an active compound isolated from the leaves of
Syzygium samarangense. In the present study, the anti-inflammatory
effects and underlying mechanisms of stercurensin were examined using
lipopolysaccharide (LPS)-stimulated RAW264.7 cells and mice. To
determine the effects of stercurensin in vitro, inducible nitric oxide
synthase (iNOS) and cyclooxygenase-2 (COX-2) expression were analyzed
by RT-PCR and immunoblotting. Nuclear factor-kappa B (NF-kappa B)
activation and its upstream signaling cascades were also investigated
using a dual-luciferase reporter assay, electrophoretic mobility shift
assay, immunoblotting, immunofluorescence, and immunoprecipitation. To
verify the effects of stercurensin in vivo, the mRNA expression levels
of iNOS and COX-2 were evaluated in isolated mouse peritoneal
macrophages by quantitative real-time PCR, and the production of tumor
necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), and IL-1 beta
were assessed in serum samples from mice using a Luminex system.
Pretreatment with stercurensin reduced LPS-induced iNOS and COX-2
expression, thereby inhibiting nitric oxide (NO) and prostaglandin E-2
production, respectively. In addition, an inhibitory effect of
stercurensin on NF-kappa B activation was shown by the recovery of
LPS-induced inhibitor of kappa B (1-kappa B) degradation after blocking
the transforming growth factor-beta-activated kinase 1 (TAK1)/I-kappa B
kinase signaling pathway. In mouse models, stercurensin negatively
regulated NF-kappa B-dependent pro-inflammatory mediators and
cytokines. These results demonstrate that stercurensin modulates
NF-kappa B-dependent inflammatory pathways through the attenuation of
TAK1-TAB1 complex formation. Our findings demonstrating the
anti-inflammatory effects of stercurensin in vitro and in vivo will aid
in understanding the pharmacology and mode of action of stercurensin. J
Cell. Biochem. 112: 548-558, 2011. (C) 2010 Wiley-Liss, Inc.
UT WOS:000287071900023
SN 0730-2312
doi 10.1002/jcb.22945

Publication type J
Title Vandetanib Plus Pemetrexed for the Second-Line Treatment of Advanced
Non-Small-Cell Lung Cancer: A Randomized, Double-Blind Phase III Trial
Author/s de Boer, RH  Arrieta, O Yang, CH Gottfried, M Chan, V Raats, J de Marinis, F
Abratt, RP Wolf, J Blackhall, FH Langmuir, P Milenkova, T Read, J Vansteenkiste, JF
Vol 29
Issue 8
Start page 1067
End page 1074
Publication year 2011
Times cited 1
Abstract Purpose
Vandetanib is a once-daily oral inhibitor of vascular endothelial
growth factor receptor and epidermal growth factor receptor signaling.
This randomized, placebo-controlled phase III study assessed the
efficacy of vandetanib plus pemetrexed as second-line therapy in
advanced non-small-cell lung cancer.
Patients and Methods
Patients (N = 534) were randomly assigned to receive vandetanib 100
mg/d plus pemetrexed 500 mg/m(2) every 21 days (n = 256) or placebo
plus pemetrexed (n = 278). Progression-free survival (PFS) was the
primary end point; overall survival, objective response rate, disease
control rate, time to deterioration of symptoms, and safety were
secondary assessments.
There was no significant difference in PFS between treatment arms
(hazard ratio [HR], 0.86; 97.58% CI, 0.69 to 1.06; P = .108). Overall
survival was also not significantly different (HR, 0.86; 97.54% CI,
0.65 to 1.13; P = .219). Statistically significant improvements in
objective response rate (19% v 8%; P < .001) and time to deterioration
of symptoms (HR, 0.71; P = .0052; median, 18.1 weeks for vandetanib and
12.1 weeks for placebo) were observed in patients receiving vandetanib.
Adding vandetanib to pemetrexed increased the incidence of some adverse
events, including rash, diarrhea, and hypertension, while showing a
reduced incidence of nausea, vomiting, anemia, fatigue, and asthenia
with no reduction in the dose intensity of pemetrexed.
This study did not meet the primary end point of statistically
significant PFS prolongation with vandetanib plus pemetrexed versus
placebo plus pemetrexed. The vandetanib combination showed a
significantly higher objective response rate and a significant delay in
the time to worsening of lung cancer symptoms versus the placebo arm as
well as an acceptable safety profile in this patient population. J Clin
Oncol 29:1067-1074. (c) 2011 by American Society of Clinical Oncology
UT WOS:000288161000032
SN 0732-183X
doi 10.1200/JCO.2010.29.5717

Publication type J
Title Characterization of CTLA-4, PD-1 and PDL-1 of swamp and riverine type
water buffaloes
Author/s Mingala, CN Konnai, S Ikebuchi, R Ohashi, K
Vol 34
Issue 1
Start page 55
End page 63
Publication year 2011
Times cited 0
Abstract Characterization of CTLA-4, PD-1 and PDL-1 genes from swamp and
riverine type water buffaloes was done by molecular cloning, sequencing
and phylogenetic analysis. The cloned cDNA of CTLA-4, PD-1 and PDL-1
contained an open reading frame of 666, 849 and 870 nucleotides,
encoding a polypeptide of 221, 282 and 298 amino acids, respectively.
Nucleotide sequence homology of both CTLA-4 and PDL-1 had 99.8% in
swamp and riverine type, which gives the identical polypeptide.
Meanwhile, PD-1 genes of swamp and riverine type water buffaloes had
99.2% of homology in nucleotide sequence, which has substitution of two
amino acid residues. The hexapeptide motif, phosphatidylinositol
3′-kinase and potential glycosylation sites were conserved within the
tribe Bovinae. Phylogenetic analysis confirmed the degree of
relationship between the bubaline species and justify the distinctness
of each breeds by the bootstrap value generated. (C) 2010 Elsevier Ltd.
All rights reserved.
UT WOS:000288299500009
SN 0147-9571
doi 10.1016/j.cimid.2010.02.002

Publication type J
Title Effects of telmisartan, irbesartan, valsartan, candesartan, and
losartan on cancers in 15 trials enrolling 138 769 individuals The ARB
Trialists Collaboration
Author/s Teo, KK Sleight, P Gao, P Yusuf, S Connolly, S Yusuf, S Swedberg, K Pfeffer, MA Granger, CB McMurray, JJV Sjoelie, AK Massie, BM Carson, P Lewis, JB Wachtell, K Dahlof, B Devereux, RB Kjeldsen, SE Julius, S Ibsen, H Lindholm, LH Olsen, MH Okin, PM Califf, R Holman, RR Haffner, SM Dagenais, G Probstfield, J Anderson, C Diaz, R Dans, A Levine, M Unger, T Fagard, R Diener, HC Sacco, RL Zanchetti, A Cohn, JN Weber, M
Vol 29
Issue 4
Start page 623
End page 635
Publication year 2011
Times cited 0
Abstract Background Angiotensin-converting enzyme inhibitors (ACEi) and
angiotensin II receptor blockers (ARBs) reduce cardiovascular disease
(CVD) events, but a recent meta-analysis of selected studies suggested
that ARBs may increase cancer risks.
Objective Candesartan, irbesartan, telmisartan, valsartan, and losartan
were assessed for incident cancers in 15 large parallel long-term
multicenter double-blind clinical trials of these agents involving 138
769 participants.
Patients and methods Individuals at high CVD risk were randomized to
telmisartan (three trials, n=51 878), irbesartan (three trials, n=14
859), valsartan (four trials, n=44 264), candesartan (four trials, n=18
566), and losartan (one trial, n=9193) and followed for 23-60 months.
Incident cancer cases were compared in patients randomized to ARBs
versus controls. In five trials (n=42 403), the ARBs were compared to
ACEi and in 11 trials (n=63 313) to controls without ACEi. In addition,
in seven trials (n=47 020), the effect of ARBs with ACEi was compared
to ACEi alone and in two trials ARBs with ACEi versus ARB alone (n=25
Results Overall, there was no excess of cancer incidence with ARB
therapy compared to controls in the 15 trials [ 4549 (6.16%) cases of
73 808 allocated to ARB versus 3856 (6.31%) of 61 106 assigned to
non-ARB controls; odds ratio (OR) 1.00, 95% confidence interval (CI)
0.95-1.04] overall or when individual ARBs were examined. ORs comparing
combination therapy with ARB along with ACEi versus ACEi was 1.01 (95%
CI 0.94-1.10), combination versus ARB alone 1.02 (95% CI 0.91-1.13),
ARB alone versus ACEi alone 1.06 (95% CI 0.97-1.16) and ARB versus
placebo/control without ACEi 0.97 (95% CI 0.91-1.04). There was no
excess of lung, prostate or breast cancer, or overall cancer deaths
associated with ARB treatment.
Conclusion There was no significant increase in the overall or
site-specific cancer risk from ARBs compared to controls. J Hypertens
29: 623-635 (C) 2011 Wolters Kluwer Health vertical bar Lippincott
Williams & Wilkins.
UT WOS:000288199500001
SN 0263-6352
doi 10.1097/HJH.0b013e328344a7de

Publication type J
Title Effect of Drought on Yield and Drought Susceptibility Index for Quality
Characters of Promising Rice Genotypes
Author/s Mall, AK Swain, P Das, S Singh, ON Kumar, A
Vol 39
Issue 1
Start page 22
End page 31
Publication year 2011
Times cited 0
Abstract Twenty-four promising drought tolerant genotypes of IRRI and different
parts of India were evaluated for genetic variability and drought
susceptibility index (DSI) for 12 quality characters and grain yield
under irrigated (E-1) and drought (E-2) conditions. In the present
study differences among the genotypes are highly significant for all
the characters; between the environments head rice recovery, alkali
spreading value, water uptake, kernel length after cooking and yield
were significant, while genotype x environment interaction was only
significant for hulling, milling, head rice recovery and water uptake.
Head rice recovery, alkali spreading value, water uptake and amylose
content were observed to be governed by additive gene action under both
the environments. Grain yield was positively correlated with kernel
width and amylose content under stress environment while, kernel width
was positively correlated with hulling and milling and kernel length
was correlated with amylose content. The path coefficient analysis
revealed that only kernel width in both the environments and amylose
content in E2 had positive direct effect on yield. Most of the
genotypes expressed low DSI value (< 1) for yield and quality
characters. However, Swarna and IR 78877-181-B-1-2 were identified as
stable genotypes with low DSI value for seed yield and quality
UT WOS:000288163200003
SN 0133-3720
doi 10.1556/CRC.39.2011.1.3

Publication type J
Title Dopamine D-1 receptor-mediated inhibition of NADPH oxidase activity in
human kidney cells occurs via protein kinase A-protein kinase C cross
Author/s Yu, PY Han, WX Villar, VM Li, HW Arnaldo, FB Concepcion, GP Felder, RA Quinn, MT Jose, PA
Vol 50
Issue 7
Start page 832
End page 840
Publication year 2011
Times cited 0
Abstract Dopamine cellular signaling via the D-1 receptor (D1R) involves both
protein kinase A (PKA) and protein kinase C (PKC), but the PKC isoform
involved has not been determined. Therefore, we tested the hypothesis
that the inhibition NADPH oxidase activity involves cross talk between
PKA and a specific PKC isoform(s). In HEK-293 cells heterologously
expressing human D1R (HEK-hD(1)), fenoldopam, a D1R agonist, and
phorbol 12-myristate 13-acetate (PMA), a PKC activator, inhibited
oxidase activity in a time- and concentration-dependent manner. The
D1R-mediated inhibition of oxidase activity (68.1 +/- 3.6%) was
attenuated by two PKA inhibitors, H89 (10 mu mol/L; 88 +/- 8.1%) and
Rp-cAMP (10 mu mol/L; 97.7 +/- 6.7%), and two PKC inhibitors,
bisindolylmaleimide 1 (1 mu Mol/L; 94 +/- 6%) and staurosporine (10
nmol/L; 93 +/- 8%), which by themselves had no effect (n = 4-8/group).
The inhibitory effect of PMA (1 mu mol/L) on oxidase activity (73 +/-
3.2%) was blocked by H89 (100 +/- 7.8%; n = 5 or 6/group). The
PMA-mediated inhibition of NADPH oxidase activity was accompanied by an
increase in PKC theta(S676), an effect that was also blocked by H89.
Faoldopam (1 mu mol/L) also increased PKC theta(S676) in HEK-hD(1) and
human renal proximal tubule (RPT) cells. Krockdown of PKC theta with
siRNA in RPT cells prevented the inhibitory effect of fenoldopam on
NADPH oxidase activity. Our studies demonstrate for the first time that
cross talk between PKA and PKC theta plays an important role in die
D1R-mediated negative regulation of NADPH oxidase activity in human
kidney cells. (C) 2010 Elsevier Inc. All rights reserved.
UT WOS:000288288700007
SN 0891-5849
doi 10.1016/j.freeradbiomed.2010.12.027

Publication type J
Title Expert recommendations for the diagnosis and treatment of
iron-deficiency anemia during pregnancy and the postpartum period in
the Asia-Pacific region
Author/s Breymann, C Bian, XM Blanco-Capito, LR Chong, C Mahmud, G Rehman, R
Vol 39
Issue 2
Start page 113
End page 121
Publication year 2011
Times cited 0
Abstract Anemia during pregnancy and the postpartum period is commonly caused by
iron deficiency and is a significant worldwide issue with severe
consequences for both mother and developing fetus. From a worldwide
perspective, iron-deficiency anemia (IDA) during pregnancy is highest
in the Asia-Pacific region; however, there has been little guidance in
this region for safe and effective treatment. An expert panel was
convened to develop a concise and informative set of recommendations
for the treatment of IDA in pregnant and postpartum women in the
Asia-Pacific region. This manuscript provides these recommendations and
aims to reduce the morbidity and mortality associated with IDA in
pregnant and postpartum women in the Asia-Pacific region. The consensus
recommendations define anemia as a hemoglobin (Hb) level < 10.5 g/dL
during pregnancy and < 10 g/dL during the postpartum period, and
provide cut-off Hb levels to initiate therapy with oral iron,
intravenous iron or red blood cell transfusion.
UT WOS:000288245600002
SN 0300-5577
doi 10.1515/JPM.2010.132

Publication type J
Title In the Shape of Tradition-Indigenous Art of the Northern Philippines
Author/s Labrador, AMTP
Journal source ARTS OF ASIA
Vol 41
Issue 1
Start page 132
End page 134
Publication year 2011
Times cited 0
UT WOS:000287063300012
SN 0004-4083

Publication type J
Title Use of a TriPollar radio-frequency device for the treatment of acne
Author/s Yu, JNT Huang, P
Vol 13
Issue 2
Start page 50
End page 53
Publication year 2011
Times cited 0
Abstract Introduction : Acne vulgaris is a common disease affecting mainly
teenagers and young adults. Current treatment modalities include local
or systemic medications, which often require a long intake. Light and
radio-frequency (RF) devices have recently been used to treat acne in
selected patients. Objective : To evaluate the safety and efficacy of
TriPollar RF technology for non-invasive treatment of acne vulgaris
lesions. Methods : Twenty patients with active acne lesions underwent
TriPollar RF treatments once a week for 6 weeks. Results were evaluated
using photographs and active lesion counts at baseline, before
subsequent treatment sessions and at follow-up visits. Patients also
rated their satisfaction on a 5-score rating scale. Results : An
average reduction of 42% in active acne lesions was found after six
TriPollar sessions, which was sustained at the 4-week follow-up visit.
The average improvement rated by patients at the 4-week follow-up visit
was 2.5, indicating good to very good satisfaction with the clinical
results. No significant adverse events were recorded during the study
and follow-up period. Conclusion : The findings confirm the safety and
efficacy of TriPollar RF for the treatment of acne vulgaris.
UT WOS:000288323900004
SN 1476-4172
doi 10.3109/14764172.2011.564626

Publication type J
Title Examining the assumptions of integrated coastal management: Stakeholder
agendas and elite cooption in Babuyan Islands, Philippines
Author/s Larsen, RK Acebes, JM Belen, A
Vol 54
Issue 1
Start page 10
End page 18
Publication year 2011
Times cited 0
Abstract In the Philippines, Integrated Coastal Management (ICM) represents the
dominant response to narratives of ecosystem decline. However, there
are persistent challenges to implementation, manifested in continued
resource degradation, questioning of the exercise of stakeholder
involvement and rising resource conflicts. This paper examines the
implementation process and how the assumptions embodied in the ICM
regime meet the local reality in one group of islands in the Philippine
archipelago. The evidence shows how the transformation towards a
supposed equilibrium state of coastal ecosystems is undermined in the
face of diverging stakeholder agendas. Expected actors are disempowered
by the incoherence between the policy owners’ worldview and reality,
paving the way for unethical influence from elite alliances. This is
coupled with a deepening of the dominance of state, international
development banks, foreign aid agencies, and NGOs in promoting their
respective interests. In localities such as the Babuyan Islands, when
assumptions of ICM collapse it has destructive consequences for
fisherfolk and the coastal environment. We conclude that if ICM is to
foster an effective and equitable correction of current unsustainable
exploitation patterns, then there is a need to institute improved
accountability mechanisms in the devolved governance system as well as
taking seriously the espoused commitment to stakeholder involvement in
determining the goals and assumptions of ICM. (c) 2010 Elsevier Ltd.
All rights reserved.
UT WOS:000287072100002
SN 0964-5691
doi 10.1016/j.ocecoaman.2010.10.007

Publication type J
Title Transition from common to private coasts: Consequences of privatization
of the coastal commons
Author/s Cabral, RB Alino, PM
Vol 54
Issue 1
Start page 66
End page 74
Publication year 2011
Times cited 0
Abstract Privatization is often viewed to provide positive stimulus for the
economy that can lead to the betterment of society. But when the
appropriate governance systems are not functionally in place, the
unwanted effects of privatization can have deleterious consequences.
This paper highlights the consequences of undesirable privatization and
the emergent unwanted privatization tendencies of the coastal commons,
particularly in the developing countries such as the Philippines. The
lack of coherent policies, standards, and weak enforcement of policies
in leasing the coastal commons (e.g. various unregulated aquaculture)
in the Philippines in particular, have resulted to alarming
displacement, deprivation and marginalization of fishing and farming
communities and have degraded many coastal zone areas. In addition,
poorly planned coastal tourism and housing development projects in the
foreshore areas, inappropriate reclamation of coastal areas, illegal
usurpation of indigenous people’s rights over ancestral domain areas,
and conversion of fishing and fish farming zones into ecotourism zones
further aggravated this scenario. Equitable access to resources is of
paramount importance to afford concerned stakeholders greater
participation in terms of developing greater capacity for coastal
communities to engage and demand for improved coastal governance an
important facet of public administration often identified as one of the
challenges in managing the commons. Co-management with an
Ecosystem-Based Management approach as core operational mechanism
provides opportunities to enhance policy formulation and
implementation, secure community safety nets, and facilitate the
creation of a level-playing environment that help to prevent the
unwanted effects of privatization. (c) 2010 Elsevier Ltd. All rights
UT WOS:000287072100007
SN 0964-5691
doi 10.1016/j.ocecoaman.2010.10.023

Publication type J
Title Auditory sensitivity of the Philippine tarsier, Tarsius syrichta
Author/s Ramsier, MACunningham, AJMoritz, GLWilliams, CVOng, PSDominy, NJ
CT 80th Annual Meeting of the
CY APR 11-16, 2011
CL Minneapolis, MN
Vol 144
Start page 247
End page 248
Publication year 2011
Times cited 0
UT WOS:000288034000686
SN 0002-9483

Publication type J
Title Characterization of statistical features for plant microRNA prediction
Author/s Thakur, V Wanchana, S Xu, M Bruskiewich, R Quick, WP Mosig, A Zhu, XG
Journal source BMC GENOMICS
Vol 12
Publication year 2011
Times cited 0
Abstract Background: Several tools are available to identify miRNAs from
deep-sequencing data, however, only a few of them, like miRDeep, can
identify novel miRNAs and are also available as a standalone
application. Given the difference between plant and animal miRNAs,
particularly in terms of distribution of hairpin length and the nature
of complementarity with its duplex partner (or miRNA star), the
underlying (statistical) features of miRDeep and other tools, using
similar features, are likely to get affected.
Results: The potential effects on features, such as minimum free
energy, stability of secondary structures, excision length, etc., were
examined, and the parameters of those displaying sizable changes were
estimated for plant specific miRNAs. We found most of these features
acquired a new set of values or distributions for plant specific
miRNAs. While the length of conserved positions (nucleus) in mature
miRNAs were relatively longer in plants, the difference in distribution
of minimum free energy, between real and background hairpins, was
marginal. However, the choice of source (species) of background
sequences was found to affect both the minimum free energy and miRNA
hairpin stability. The new parameters were tested on an Illumina
dataset from maize seedlings, and the results were compared with those
obtained using default parameters. The newly parameterized model was
found to have much improved specificity and sensitivity over its
default counterpart.
Conclusions: In summary, the present study reports behavior of few
general and tool-specific statistical features for improving the
prediction accuracy of plant miRNAs from deep-sequencing data.
UT WOS:000288204300001
SN 1471-2164
doi 10.1186/1471-2164-12-108

Publication type J
Title Identification of QTLs for hybrid fertility in inter-subspecific
crosses of rice (Oryza sativa L.)
Author/s Chin, JH Chu, SH Jiang, W Cho, YI Basyirin, R Brar, DS Koh, HJ
Journal source GENES & GENOMICS
Vol 33
Issue 1
Start page 39
End page 48
Publication year 2011
Times cited 0
Abstract Two subspecies in rice, japonica and indica, have their own ecotypic
traits. However, reproductive barriers such as spikelet sterility in
hybrid progenies between subspecies have been an obstacle in breeding
programs for combining desirable traits from both subspecies through
inter-subspecific hybridization. The 166 F-9 RILs and two BC(1)F(1)s’
were analyzed for spikelet and pollen fertility with the parents and
F-1 between Dasanbyeo (DS, indica) / TR22183 (TR, japonica). A frame
map was constructed using a total of 218 polymorphic STS and SSR
markers. In both BC(1)F(1)s’ of DS//DS/TR and TR//DS/TR, clusters of
significant QTLs for spikelet and pollen fertility were identified on
the short arm of chromosome 5 and chromosome 8. Nine and ten digenic
epistatic interactions for DS//DS/TR and TR//DS//TR were identified,
respectively. HF-QTLs were detected at the similar position with
subspecies-specific markers and segregation distortion loci, implying
that HF-QTLs might be associated with the differentiation of indica and
japonica. Hybrid fertility/sterility and its relationship with other
traits are discussed in relation to the reproductive barriers between
subspecies of rice.
UT WOS:000287969000006
SN 1976-9571
doi 10.1007/s13258-010-0100-z

Publication type J
Author/s Tioleco, PS Nilo, GS Tanael, SB
Vol 41
Issue 3
Start page I3
End page I3
Publication year 2011
Times cited 0
UT WOS:000288019700004
SN 0368-2811
doi 10.1093/jjco/hyq252

Publication type J
Title Doubly Robust and Multiple-Imputation-Based Generalized Estimating
Author/s Birhanu, T Molenberghs, G Sotto, C Kenward, MG
Vol 21
Issue 2
Start page 202
End page 225
Publication year 2011
Times cited 0
Abstract Generalized estimating equations (GEE), proposed by Liang and Zeger
(1986), provide a popular method to analyze correlated non-Gaussian
data. When data are incomplete, the GEE method suffers from its
frequentist nature and inferences under this method are valid only
under the strong assumption that the missing data are missing
completely at random. When response data are missing at random, two
modifications of GEE can be considered, based on inverse-probability
weighting or on multiple imputation. The weighted GEE (WGEE) method
involves weighting observations by the inverse of their probability of
being observed. Imputation methods involve filling in missing
observations with values predicted by an assumed imputation model,
multiple times. The so-called doubly robust (DR) methods involve both a
model for the weights and a predictive model for the missing
observations given the observed ones. To yield consistent estimates,
WGEE needs correct specification of the dropout model while
imputation-based methodology needs a correctly specified imputation
model. DR methods need correct specification of either the weight or
the predictive model, but not necessarily both. Focusing on incomplete
binary repeated measures, we study the relative performance of the
singly robust and doubly robust versions of GEE in a variety of
correctly and incorrectly specified models using simulation studies.
Data from a clinical trial in onychomycosis further illustrate the
UT WOS:000288281800004
SN 1054-3406
doi 10.1080/10543406.2011.550096

Publication type J
Title Xanthine oxidase inhibition of selected Philippine medicinal plants
Author/s Apaya, KL Chichioco-Hernandez, CL
Vol 5
Issue 2
Start page 289
End page 292
Publication year 2011
Times cited 0
Abstract Extracts from selected species of Philippine plants traditionally used
for their anti-inflammatory properties were examined for their ability
to inhibit the action of xanthine oxidase. The degree of inhibition
using Adenanthena payonina, Antegonon leptopus, Blumea balsamifera,
Calophyllum inophyllum, Cassia alata, Cassia fistula, Gliricidia
sepium, Michelia alba, Mimosa pudica, Portulaca olercea, Pogostemon
cablin, Solanum tornum, Tinosphora rumphii and Vitex negundo extracts
were determined by measuring the increase in absorbance at 295 nm which
is associated with uric acid formation which is linked to gout. B.
balsamifera has the highest percent inhibition at 79.67% followed by M.
pudica with 62.36% inhibition. The xanthine oxidase inhibitory
potential and IC50 values of the extracts are reported.
UT WOS:000287938900023
SN 1996-0875

Publication type J
Title Harvest optimization of four Kappaphycus species from the Philippines
Author/s Villanueva, RD Romero, JB Montano, MNE de la Pena, PO
Journal source BIOMASS & BIOENERGY
Vol 35
Issue 3
Start page 1311
End page 1316
Publication year 2011
Times cited 0
Abstract The booming seaweed industry in the Philippines has been recently
challenged by several problems, including the degrading quality of
carrageenan extracts from farmed Kappaphycus species. One emerging
concern is the correctness of certain agronomic protocols, specifically
the recommended duration of culture of farmed seaweeds. We determined
in this study the effect of duration of culture on seaweed biomass and
carrageenan quantity and quality of four commercially farmed
Kappaphycus species. A mathematical formula was then employed to derive
a weekly optimization index (a metric incorporating several parameters
or product attributes, viz., biomass, carrageenan yield and gel
strength) which was used to determine the appropriate time of harvest.
The Kappaphycus species exhibited c. 300% increase in biomass within
4-7 weeks in culture (c. 150 g from an initial biomass of 50 g wet
weight) and then a biomass plateau was observed. Carrageenan yield in
all seaweeds fluctuated minimally (mean: 55-58%; s.d.: 2-4%), however,
gel strength peaked at 8-9 weeks of culture. Highest optimization index
was obtained during week 8 for Kappaphycus alvarezii var. alvarezii and
week 9 for the rest of the cultured seaweeds (Kappaphycus striatum var.
sacol, Kappaphycus sp. “aring-aring” and Kappaphycus sp. “duyan”);
hence, the recommended harvest times for the respective seaweeds are
during these weeks of culture. As several seaweed manuals recommend
other culture durations, a revision of these is appealed in order to
safeguard the quality of farmed Kappaphycus species. (C) 2010 Elsevier
Ltd. All rights reserved.
UT WOS:000288306700038
SN 0961-9534
doi 10.1016/j.biombioe.2010.12.044

Publication type J
Title The Role of Endoscopic Nephron-Sparing Surgery in the Management of
Upper Tract Urothelial Carcinoma
Author/s Raymundo, EM Lipkin, ME Banez, LB Mancini, JG Zilberman, DE Preminger, GM Inman, BA
Vol 25
Issue 3
Start page 377
End page 384
Publication year 2011
Times cited 0
Abstract Introduction: Upper tract urothelial carcinoma (UT-UC) is an uncommon
disease with pronounced difference in 5-year survival for noninvasive
(96%) versus invasive (17%) disease. High survival rate of early
disease questioned the accepted norm of using radical
nephroureterectomy (RNU) for all stages. This review assesses
effectiveness of endoscopic management for UT-UC.
Methods: A review of 131 UT-UC patients seen between January 1999 and
October 2009 was performed. Demographic, clinicopathologic, and
outcomes data were collected and compared between patients initially
managed with RNU versus those initially managed with nephron-sparing
surgery (NSS). The chi-square or Fisher’s exact tests for categorical
variables and the Wilcoxon-Mann-Whitney test for continuous variables
were used. Clinical and pathologic stages of RNU patients were
evaluated with chi-square testing, whereas difference in length of stay
was detected using linear regression. Recurrence rates were compared
using multivariate Cox regression.
Results: The two arms had similar distributions of age, sex, frequency
of medical comorbidities, American Society of Anesthesiologists (ASA),
and Charlson scores. Mean-adjusted length of stay was 2.1 (95%
confidence interval [1.6, 2.5]) and 5.5 days (95% confidence interval
[5.3, 6.4]) for the NSS and RNU groups, respectively (p < 0.001).
Comparison of clinical and pathologic stages of RNU patients showed a
difference (p < 0.001), with under-staging noted in 32%. Men (Hazards
Ratio 2.9 [1.5-5.5], p = 0.001) and NSS patients (hazards ratio [HR] =
3.5 [1.7-7.3], p < 0.001) had threefold increased recurrence risk.
Conclusion: NSS offered shorter hospital stay but had increased risk of
recurrence. Therefore, extreme care should be made to rule out occult
invasive tumors preoperatively. Patients being managed endoscopically
must be informed of the necessity for close follow-up.
UT WOS:000288368400003
SN 0892-7790
doi 10.1089/end.2010.0276

Publication type J
Title Two-Way Coupled Atmosphere-Ocean Modeling of the PhilEx Intensive
Observational Periods
Author/s May, PW Doyle, JD Pullen, JD David, LT
Journal source OCEANOGRAPHY
Vol 24
Issue 1
Start page 48
End page 57
Publication year 2011
Times cited 5
Abstract High-resolution coupled atmosphere-ocean simulations of the Philippines
show the regional and local nature of atmospheric patterns and ocean
response during Intensive Observational Period cruises in
January-February 2008 (IOP-08) and February March 2009 (IOP-09) for the
Philippine Straits Dynamics Experiment. Winds were stronger and more
variable during IOP-08 because the time period covered was near the
peak of the northeast monsoon season. Distinct wind jets between
islands and wakes behind islands are common northeast monsoon features
that are controlled by winds interacting with island topography: The
modeled upper-ocean flow associated with Philippine straits during
IOP-08 exhibits large (> 1 m s(-1)) westward mean flow through Suriago
Strait and highly variable flow through Mindoro Strait. The model shows
prominent eddies in the Bohol Sea and Cuyo East Pass that were also
observed during the field experiment. A high-resolution nested
simulation of the Verde Island Passage finds local wind-driven
upwelling that is confirmed by shipboard sea surface temperature
measurements and satellite observations of chlorophyll concentration.
UT WOS:000288234000005
SN 1042-8275

Publication type J
Author/s Cabrera, OC Villanoy, CL David, LT Gordon, AL
Journal source OCEANOGRAPHY
Vol 24
Issue 1
Start page 130
End page 141
Publication year 2011
Times cited 4
Abstract The Bohol Sea is a relatively unstudied marginal sea located in the
southern part of the Philippines. Hydrographic data from the Philippine
Straits Dynamics Experiment (PhilEx) cruises reveal a complex three
dimensional circulation composed of two overturning cells that may be
referred to as “double estaurine type”. This type of overturning
circulation promotes upwelling of cold, nutrient-rich waters within the
Bohol Sea associated with entrainment and eddy processes that promote
phytoplankton blooms. Evidence from ocean color imagery supports
entrainment in the eastern basin and eddy formation in the southwestern
basin. However, PhilEx researchers found that the cyclonic Iligan Bay
Eddy in the southwestern basin did not conform to the paradigm of
cyclonic eddy upwell. Although upwelling was evident through doming
isotherms within the water column, the surface projection of this
signal was suppressed by the presence of a thick barrier layer,
particularly during cruises on December 2007 and January 2008. I known
La Nina period. Long-term trends in chlorophyll data followed trends in
rainfall and the ENSO 3.4 index, with elevated (reduced) chlorophyll
during dry El Nino years (Wet La Nina years). By promoting stability of
surface layer stratification and preventing vertical transport of
nutrients, the barrier layer is thus a mechanism by which the El
Nino-Southern Oscillation influences phytoplankton biomass in the Bohol
UT WOS:000288234000012
SN 1042-8275

Publication type J
Author/s Jones, BH Lee, CM Toro-Farmer, G Boss, ES Gregg, MC Villanoy, CL
Journal source OCEANOGRAPHY
Vol 24
Issue 1
Start page 142
End page 155
Publication year 2011
Times cited 3
Abstract Measurements in San Bernardino Strait, one of two major connections
between the Pacific Ocean and the interior waters of the Philippine
Archipelago, captured 2-3 m s(-1) tidal currents that drove vertical
mixing and net landward transport. A TRIAXUS towed profiling vehicle
equipped with physical and optical sensors was used to repeatedly map
subregions within the strait, employing survey patterns designed to
resolve tidal variability of physical and optical properties. Strong
flow over the sill between Luzon and Capul islands resulted in upward
transport and mixing of deeper high-salinity, low-oxygen,
high-particle-and-nutrient-concentration water into the upper water
column, landward of the sill. During the high-velocity ebb flow,
topography influences the vertical distribution of water, but without
the diapycnal mixing observed during flood tide. The surveys captured a
net landward flux of water through the narrowest part of the strait.
The tidally varying velocities contribute to strong vertical transport
and diapycnal mixing of the deeper water into the upper layer,
contributing to the observed higher phytoplankton biomass within the
interior of the strait.
UT WOS:000288234000013
SN 1042-8275

Publication type J
Title Monsoon-Driven Coastal Upwelling Off Zamboanga Peninsula, Philippines
Author/s Villanoy, CL Cabrera, OC Yniguez, A Camoying, M de Guzman, A David, LT Flament, P
Journal source OCEANOGRAPHY
Vol 24
Issue 1
Start page 156
End page 165
Publication year 2011
Times cited 3
Abstract Cooler temperatures and elevated chlorophyll a, indicative of
upwelling, are observed off the coast of Zamboanga Peninsula,
Philippines. This upwelling is driven primarily by offshore Ekman
transport as the northeast monsoon winds blow parallel along the coast
of Zamboanga, with enhancement of positive wind stress curl due to the
land’s frictional retrading force. Analysis of sea surface temperature
time series reveals interannual variations in upwelling, with weakening
during the 2007/2008 La Nina and strengthening during the 2006/2007 El
Nino. Upwelling areas are known as productive and biologically rich,
and the Zamboanga upwelling supports a thriving sardine fishery in the
southern Philippines. Sardine landing data correlate remarkably well
with monthly chlorophyll values during 2009-2010. Despite the
prevailing notion that La Nina causes strengthening of the
monsoon-driven upwelling, long-term fisheries production data for
Zambonaga demonstrate a decrease in fish catch due to weaker upwelling
during the 1999/2000 and 2007/2008 La Ninas. Interannual variations in
upwelling, phytoplankton productivity, and sardine catch suggest that
internanual El Nino-Southern Oscillation variations can affect the
small Zamboanga Peninsula pelagic fishery.
UT WOS:000288234000014
SN 1042-8275

Publication type J
Title Microbial community of a volcanic mudspring in the Philippines as
revealed by 16S rDNA sequence analysis and fluorescence in situ
Author/s Lantican, NB Diaz, MGQ Cantera, JJL de los Reyes, FL Raymundo, AK
Vol 27
Issue 4
Start page 859
End page 867
Publication year 2011
Times cited 0
Abstract Mt. Makiling Mudspring in Laguna, Philippines is a thermophilic,
acidophilic environment that previously has been shown to harbor novel
microorganisms. We assessed the microbial community that exists at this
volcanic mudspring using 16S rRNA-based approaches. DNA was extracted
from solfataric soils and sediments taken from Mudspring. The 16S rDNA
was PCR amplified using universal (519F-1392R) and archaeal-specific
(23FPL-1391R) primer pairs, cloned, and sequenced. Phylogenetic
analysis of the cloned 16S rDNA showed that eleven clones clustered
with, and therefore related to Sulfolobus tokodaii 7 and two clones
clustered with S. solfataricu, S. shibatae and S. islandicus. Three
clone sequences were related to those found in thermophilic
chalcopyrite (CuFeS2), a copper sulfuric ore from bioleaching reactors.
One clone had low similarity (95% identity) with uncultured archaeon
clone KOZ184. Fluorescence in situ hybridization (FISH) analysis
revealed that about 71% of the microbial community present in the
Mudspring belong to domain Archaea of which 63% were Crenarchaeota and
8% were Euryarchaeota. Seventeen percent (17%) of the population
consisted of bacteria as indicated by the positive hybridization with
the BACT338 probe, and the remaining 12% are unidentified. This study
is the first attempt to use molecular techniques in any environment in
the Philippines.
UT WOS:000288252400016
SN 0959-3993
doi 10.1007/s11274-010-0528-y

Publication type J
Title Purification, characterization and in vitro cytotoxicity of the
bacteriocin from Pediococcus acidilactici K2a2-3 against human colon
adenocarcinoma (HT29) and human cervical carcinoma (HeLa) cells
Author/s Villarante, KI Elegado, FB Iwatani, S Zendo, T Sonomoto, K de Guzman, EE
Vol 27
Issue 4
Start page 975
End page 980
Publication year 2011
Times cited 0
Abstract A bacteriocinogenic lactic acid bacterium (designated K2a2-3) isolated
from the intestine of Philippine water buffalo was identified as
Pediococcus acidilactici by 16S rRNA gene sequence analysis. The
bacteriocin was purified by hydrophobic interaction chromatography,
cation-exchange chromatography and reverse phase-high performance
liquid chromatography. The purified protein has a molecular mass of
4,625.91 Da, quantified by electrospray ionization time-of-flight mass
spectrometry. Based on a BLAST homology search of a partial sequence of
39 amino acid residues and the presence of the structural gene papA,
detected through polymerase chain reaction, it was identified as very
similar to pediocin PA-1. It was active against a wide spectrum of
lactic acid bacteria and Listeria innocua. Partially-purified
bacteriocin samples, conducted using pH-mediated bacteriocin extraction
method, were found to be cytotoxic against human colon adenocarcinoma
(HT29) and human cervical carcinoma (HeLa) cells in vitro, as
determined by MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium
bromide] assay.
UT WOS:000288252400029
SN 0959-3993
doi 10.1007/s11274-010-0541-1

Publication type J
Title The science-policy interface for safeguarding key biodiversity areas
Author/s Brooks, TM Matiku, P
Vol 14
Issue 2
Start page 111
End page 113
Publication year 2011
Times cited 1
UT WOS:000288450700003
SN 1367-9430
doi 10.1111/j.1469-1795.2011.00452.x

Publication type J
Title Growth, yield and water productivity of zero till wheat as affected by
rice straw mulch and irrigation schedule
Author/s Balwinder-Singh Humphreys, E Eberbach, PL Katupitiya, A Yadvinder-Singh Kukal, SS
Vol 121
Issue 2
Start page 209
End page 225
Publication year 2011
Times cited 0
Abstract Intensive cultivation of rice and wheat in north-west India has
resulted in air pollution from rice straw burning, soil degradation and
declining groundwater resources. The retention of rice residues as a
surface mulch could be beneficial for moisture conservation and yield,
and for hence water productivity, in addition to reducing air pollution
and loss of soil organic matter. Two field experiments were conducted
in Punjab, India, to study the effects of rice straw mulch and
irrigation scheduling on wheat growth, yield, water use and water
productivity during 2006-2008. Mulching increased soil water content
and this led to significant improvement in crop growth and yield
determining attributes where water was limiting, but this only resulted
in significant grain yield increase in two instances. There was no
effect of irrigation treatment in the first year because of
well-distributed rains. In the second year, yield decreased with
decrease and delay in the number of irrigations between crown root
initiation and grain filling. With soil matric potential (SMP)-based
irrigation scheduling, the irrigation amount was reduced by 75 mm each
year with mulch in comparison with no mulch, while maintaining grain
yield. Total crop water use (ET) was not significantly affected by
mulch in either year, but was significantly affected by irrigation
treatment in the second year. Mulch had a positive or neutral effect on
grain water productivity with respect to ET (WPET) and irrigation
(WPi). Maximum WPi occurred in the treatment which received the least
irrigation, but this was also the lowest yielding treatment. The
current irrigation scheduling guidelines based on cumulative pan
evaporation (CPE) resulted in sub-optimal irrigation (loss of yield) in
one of the two years, and higher irrigation input and lower WPi of the
mulched treatment in comparison with SMP-based irrigation scheduling.
The results from this and other studies suggest that farmers in Punjab
greatly over-irrigate wheat. Further field and modelling studies are
needed to extrapolate the findings to a wider range of seasonal and
site conditions, and to develop simple tools and guidelines to assist
farmers to better schedule irrigation to wheat. (C) 2010 Elsevier B.V.
All rights reserved.
UT WOS:000288473900002
SN 0378-4290
doi 10.1016/j.fcr.2010.12.005

Publication type J
Title Row spacing and weed control timing affect yield of aerobic rice
Author/s Chauhan, BS Johnson, DE
Vol 121
Issue 2
Start page 226
End page 231
Publication year 2011
Times cited 0
Abstract Field experiments were conducted during the wet season of 2009 and dry
season of 2010 to determine the effects of row spacing and timing of
weed control on weed growth and yield of aerobic rice. Ten weed
management treatments were used to identify critical periods of weed
competition with aerobic rice grown in three different row spacings
(15-cm, 30-cm, and as paired rows 10-20-10-cm). Dominant weed species
during both growing seasons were Rottboellia cochinchinensis, Digitaria
ciliaris, Echinochloa colona, and Eleusine indica. Rice grown in 30-cm
rows had greater weed biomass and less grain yield than in 15-cm and
10-20-10-cm rows; weed growth and grain yields were similar between
15-cm and 10-20-10-cm rows. Rice yields in the wet season ranged from
170 kg ha(-1) where weeds were not controlled throughout the crop
duration to 2940 kg ha(-1) in weed-free treatment, indicating a 94%
yield loss with uncontrolled weed growth. Similarly in the dry season,
plots with no weed control (140 kg ha(-1)) compared to weed-free plots
(3640 kg ha(-1)) indicate a 96% yield loss with no weed control.
Gompertz and logistic equations were fitted to yield data resulting
from increasing durations of weed control and weed interference,
respectively. Critical periods for weed control in the wet season, to
obtain 95% of a weed-free yield, were estimated as between 18 and 52
days after sowing (DAS) for crops in rows at 15-cm, 20-51 DAS at
10-20-10-cm, and 15-58 DAS at 30-cm. These intervals in the dry season
were 17-56 DAS for crops in rows at 15-cm and 17-60 DAS at 10-20-10-cm
and 15-64 DAS at 30-cm. Durations of the critical periods in the wet
season were 31 days at 10-20-10-cm, 34 days at 15-cm and 43 days at
30-cm, while in the dry season, these were 43 days at 10-20-10-cm. 39
days at 15-cm and 49 days at 30-cm. In both seasons, crops in the wider
spacing (30-cm) were vulnerable to weed competition for the longest
period. The information gained from this study suggests that the
aerobic rice yields better in 15-cm rows and 10-20-10-cm arrangements
than in 30-cm rows and there is very little benefit of weed control
beyond 8 weeks after sowing. (C) 2010 Elsevier B.V. All rights
UT WOS:000288473900003
SN 0378-4290
doi 10.1016/j.fcr.2010.12.008

Publication type J
Title Photorefractive keratectomy using a 213 nm wavelength solid-state laser
in eyes with previous conductive keratoplasty to treat presbyopia:
Early results
Author/s Felipe, AF Agahan, ALD Cham, TL Evangelista, RP
Vol 37
Issue 3
Start page 518
End page 524
Publication year 2011
Times cited 0
Abstract PURPOSE: To evaluate the efficacy and safety of photorefractive
keratectomy (PRK) using a 213 nm wavelength solid-state laser to treat
regression in eyes that had previous conductive keratoplasty (CK) for
SETTING: Outpatient refractive surgery center, Manila, Philippines.
DESIGN: Prospective consecutive case series.
METHODS: Consecutive eyes that had previous CK for presbyopia were
treated with PRK using a 213 nm wavelength solid-state laser (Pulzar
Z1). Uncorrected near (UNVA) and distance (UDVA) visual acuities
(monocular and binocular), corrected distance visual acuity (CDVA),
refraction, keratometry, and slitlamp evidence of corneal haze and
other complications were evaluated for up to 6 months after surgery.
RESULTS: The study evaluated 20 eyes (20 patients). Six months after
PRK, 47% of eyes had monocular UNVA of Jaeger (J) 3 or better and 27%
had a binocular UDVA of 0.10 logMAR (20/25 Snellen equivalent) or
better with a concurrent UNVA of J3 or better. Seventy-three percent of
eyes were within +/- 1.00 diopter of the attempted refraction. No eye
lost 2 or more lines of CDVA or developed significant corneal haze.
CONCLUSION: Photorefractive keratectomy after CK using a 213 nm
wavelength solid-state laser produced functional visual acuity in
presbyopic patients in the short term (6 months).
UT WOS:000288416100015
SN 0886-3350
doi 10.1016/j.jcrs.2010.09.019

Publication type J
Title Health in Southeast Asia 6 Health-financing reforms in southeast Asia:
challenges in achieving universal coverage
Author/s Tangcharoensathien, V Patcharanarumol, W Ir, P Aljunid, SM Mukti, AG Akkhavong, K Banzon, E Huong, DB Thabrany, H Mills, A
Journal source LANCET
Vol 377
Issue 9768
Start page 863
End page 873
Publication year 2011
Times cited 2
Abstract In this sixth paper of the Series, we review health-financing reforms
in seven countries in southeast Asia that have sought to reduce
dependence on out-of-pocket payments, increase pooled health finance,
and expand service use as steps towards universal coverage. Laos and
Cambodia, both resource-poor countries, have mostly relied on
donor-supported health equity funds to reach the poor, and reliable
funding and appropriate identification of the eligible poor are two
major challenges for nationwide expansion. For Thailand, the
Philippines, Indonesia, and Vietnam, social health insurance financed
by payroll tax is commonly used for formal sector employees (excluding
Malaysia), with varying outcomes in terms of financial protection.
Alternative payment methods have different implications for provider
behaviour and financial protection. Two alternative approaches for
financial protection of the non-poor outside the formal sector have
emerged contributory arrangements and tax-financed schemes with
different abilities to achieve high population coverage rapidly. Fiscal
space and mobilisation of payroll contributions are both important in
accelerating financial protection. Expanding coverage of good-quality
services and ensuring adequate human resources are also important to
achieve universal coverage. As health-financing reform is complex,
institutional capacity to generate evidence and inform policy is
essential and should be strengthened.
UT WOS:000288628500034
SN 0140-6736
doi 10.1016/S0140-6736(10)61890-9

Publication type J
Title The sum of orthogonal matrices in M-n (Z(k))
Author/s Merino, DI Paras, AT Reyes, E Walls, G
Vol 434
Issue 10
Start page 2170
End page 2175
Publication year 2011
Times cited 0
Abstract We show that every A is an element of M-n (Z(2k-1)) can be written as a
sum of orthogonal matrices (QQ(T) = Q(T)Q = 1) in M-n (Z(2k-1)).
Moreover, we show that every A is an element of M-n (Z(2k)) can be
written as a sum of orthogonal matrices in M-n (Z(2k)) if and only if
the row sums and column sums of A have the same parities. (C) 2010
Elsevier Inc. All rights reserved.
UT WOS:000288481900005
SN 0024-3795
doi 10.1016/j.laa.2010.12.006

Publication type J
Title Policy and practice in the live reef fish for food trade: A case study
from Palawan, Philippines
Author/s Fabinyi, M Dalabajan, D
Journal source MARINE POLICY
Vol 35
Issue 3
Start page 371
End page 378
Publication year 2011
Times cited 0
Abstract The live reef fish for food trade is a highly significant fishery that
provides income for many coastal communities in the Asia-Pacific region
but faces challenges relating to sustainability. This paper draws
attention to the large gaps that exist between policy and practice in
the live reef fish for food trade in Palawan, Philippines. While many
policies have been introduced over many years, effective implementation
remains a challenge. We show how the implementation of successive sets
of policies has been hindered by three broadly inter-related features
of the local social landscape: the capacity of government institutions
and legal frameworks to implement regulations, the distinctive culture
of fisheries governance in the Philippines, and the perspectives and
practices of local fishers themselves. By focusing on the gaps between
policy and practice, we highlight the ongoing need to examine more
explicitly the ways in which local contexts shape the effectiveness of
implementation, enforcement and policy more generally. (C) 2010
Elsevier Ltd. All rights reserved.
UT WOS:000287276400011
SN 0308-597X
doi 10.1016/j.marpol.2010.11.001

Publication type J
Title A stimulatory effect of Cassia occidentalis on melanoblast
differentiation and migration
Author/s Babitha, S Shin, JH Nguyen, DH Park, SJ Reyes, GA Caburian, A Kim, EK
Vol 303
Issue 3
Start page 211
End page 216
Publication year 2011
Times cited 0
Abstract In vitiligo, the active melanocytes in the epidermis are totally
missing, whereas melanoblast cells in the outer root sheath of hair
follicles are not affected. In an attempt to find potent repigmenting
agents for vitiligo therapy, pod extracts of Cassia occidentalis was
found to be effective in inducing differentiation and migration of
mouse melanoblast cell line. Methanolic extract redissolved in DMSO at
12.5 mu g/ml was found to cause 3.5- to 3.8-fold melanin induction in
melb-a melanoblast cells after 4 days in treatment medium. In addition
it induced the tyrosinase activity and altered melb-a cell morphology.
Transwell migration assay showed the potential of this herbal candidate
to induce direct migration of treated cells. To the best of our
knowledge, this is the first report investigating the effect of Cassia
occidentalis on the differentiation and migration of melanoblast cells.
The findings of present study are significant in designing preclinical
and clinical studies on the efficacy of C. occidentalis as a stimulant
for skin repigmentation in vitiligo.
UT WOS:000288660000008
SN 0340-3696
doi 10.1007/s00403-011-1127-y

Publication type J
Title Spatio-temporal variation of the zooplankton community in a tropical
caldera lake with intensive aquaculture (Lake Taal, Philippines)
Author/s Papa, RDS Zafaralla, MT Eckmann, R
Journal source HYDROBIOLOGIA
Vol 664
Issue 1
Start page 119
End page 133
Publication year 2011
Times cited 0
Abstract Zooplankton were collected from Lake Taal between January and December
2008 in order to test for differences in species composition and
abundance between a lake basin with intensive fish cage (FC)
aquaculture and an open water area without FCs. Most species showed
similar patterns of occurrence in both basins while having differences
in abundance. Several rotifer species were more abundant in FC sites
most of the year, while for microcrustaceans higher abundances in FC
sites only happened during the first 2 months. Their distribution is
attributed to the presence of higher nutrient levels in FC sites as
well as wind-induced basin-wide water movements during the different
monsoon seasons which disperse plankton and nutrients from FC sites to
other parts of the lake. Zooplanktonic indicators, such as the
Brachionus-Trichocerca quotient (Q(B/T)) and the ratio of calanoids to
cladocerans and cyclopoids, clearly demonstrate the eutrophic state of
the lake. A comparison with previous studies suggests that the lake was
already eutrophic prior to the introduction of aquaculture in the
1970s. The trophic conditions in Lake Taal may be attributed to the
lakes’ tropical and volcanic nature, with productivity further enhanced
by increased nutrient input from aquaculture.
UT WOS:000288562800009
SN 0018-8158
doi 10.1007/s10750-010-0591-2

Publication type J
Title Endoscope-Assisted Removal of Intraosseous Schwannoma With Preservation
of Inferior Alveolar Nerve
Author/s Jiang, WH Brillo, GV Cheng, AHA Shen, GF Wang, XD
Vol 22
Issue 2
Start page 617
End page 619
Publication year 2011
Times cited 0
Abstract The use of endoscopes in oral and maxillofacial surgery has been well
documented. The advantage of no external scar and minimal invasiveness
makes endoscopic technique gradually more popular. This article will
describe a rare case of an intraosseous inferior alveolar nerve
schwannoma and its removal using endoscope. The surgical technique and
preservation of the inferior alveolar nerve will be described and
illustrated. The advantages and disadvantages of the approach will be
UT WOS:000288535800056
SN 1049-2275
doi 10.1097/SCS.0b013e3182085671

Publication type J
Title Immunogenicity of a Single Dose of Tetravalent Meningococcal Serogroups
A, C, W-135, and Y Conjugate Vaccine Administered to 2-to 10-year-olds
Is Noninferior to a Licensed-ACWY Polysaccharide Vaccine With an
Acceptable Safety Profile
Author/s Memish, ZA Dbaibo, G Montellano, M Verghese, VP Jain, H Dubey, AP Bianco, V Van der Wielen, M Gatchalian, SMiller, JM
Vol 30
Issue 4
Start page E56
End page E62
Publication year 2011
Times cited 0
Abstract Background: Meningococcal disease remains an important cause of
invasive bacterial infections in children less than 5 years of age.
Immunogenicity and safety of the investigational ACWY vaccine
conjugated with tetanus toxoid (ACWY-TT, GlaxoSmithKline Biologicals)
were evaluated in 1501 healthy 2- to 10-year-old children in the
Philippines, India, Lebanon, and Saudi Arabia.
Methods: Children were randomized (3:1) to receive ACWY-TT or licensed
tetravalent meningococcal polysaccharide vaccine (Mencevax,
GlaxoSmithKline, Men-PS). Diary cards were used to collect solicited
symptoms for 4 days after vaccination. Serious adverse events were
reported for 6 months. Serum bactericidal activity (rSBA, rabbit
complement) was measured before and 1 month after vaccination in the
first 75% of subjects enrolled in each country.
Results: The statistical criteria for noninferiority in terms of rSBA
vaccine responses were reached. Exploratory analyses showed that
postvaccination rSBA titers >= 1:8 and >= 1:128 were significantly
higher after ACWY-TT than Men-PS for serogroups C, W-135, and Y, and
rSBA vaccine responses and geometric mean antibody titers were
significantly higher for all 4 serogroups after administration of
ACWY-TT. Noninferiority in terms of incidences of grade 3 general
symptoms was not demonstrated. ACWY-TT was well tolerated with grade 3
events reported in <1% of subjects per group. No serious adverse events
were considered related to vaccination.
Conclusion: ACWY-TT was immunogenic in children between 2 to 10 years
of age with a clinically acceptable safety profile that resembled
licensed Men-PS. These data support a positive benefit/risk ratio for
the ACWY-TT vaccine.
UT WOS:000288438700001
SN 0891-3668
doi 10.1097/INF.0b013e31820e6e02

Publication type J
Title Palaeozoology of Palawan Island, Philippines
Author/s Piper, PJ Ochoa, J Robles, EC Lewis, H Paz, V
Vol 233
Issue 2
Start page 142
End page 158
Publication year 2011
Times cited 0
Abstract Excavations at the Ille site in north Palawan have produced a large
Terminal Pleistocene to Late Holocene faunal assemblage. Derived both
from the natural deaths of small mammals and the human hunting of large
and intermediate game, the bone assemblage provides important new
information about changes in the composition and structure of the
mammal community of Palawan over the last ca. 14 000 years. The Ille
zooarchaeological record chronicles the terrestrial vertebrate fauna of
the island, and the disappearance of several large taxa since the end
of the last glacial period due to environmental change and human
impacts. (C) 2010 Elsevier Ltd and INQUA. All rights reserved.
UT WOS:000288583400006
SN 1040-6182
doi 10.1016/j.quaint.2010.07.009

Publication type J
Title Acute Cocaine Increases Interleukin-1 beta mRNA and Immunoreactive
Cells in the Cortex and Nucleus Accumbens
Author/s Cearley, CN Blindheim, K Sorg, BA Krueger, JM Churchill, L
Vol 36
Issue 4
Start page 686
End page 692
Publication year 2011
Times cited 0
Abstract The cytokine, interleukin-1 beta (IL1 beta) is a sleep regulatory
substance whose expression is enhanced in response to neuronal
stimulation. In this study, IL1 beta mRNA and immunoreactivity (IR) are
evaluated after acute cocaine. First, IL1 beta mRNA levels were
measured at the start or end of the light period after saline or acute
exposure to a low dose of cocaine (5 mg/kg, intraperitoneal (ip)). IL1
beta mRNA levels after an acute exposure to cocaine (5 mg/kg, ip) at
dark onset were significantly higher than those obtained from rats
sacrificed after an acute exposure to saline in the piriform and
somatosensory cortex, and nucleus accumbens. Acute exposure of cocaine
at 5 mg/kg at dark onset also increased the number of IL1
beta-immunoreactive astrocytes in layer I-V of the prefrontal cortex,
somatosensory cortex and nucleus accumbens. These data suggest that IL1
beta mRNA and protein levels in some of the dopaminergically innervated
brain regions are responsive to cocaine.
UT WOS:000288664400015
SN 0364-3190
doi 10.1007/s11064-011-0410-9

Publication type J
Title Ties Binding Asia, Europe and the USA
Author/s Kim, S Lee, JW Park, CY
Journal source CHINA & WORLD ECONOMY
Vol 19
Issue 1
Start page 24
End page 46
Publication year 2011
Times cited 0
Abstract We investigate changes in Asia’s regional and global trade linkages and
their influence on macroeconomic relationships among Asia, Europe and
the USA. We first document changes in tripartite trade patterns and
discuss stylized facts about East Asia’s trade structure, with
particular focus on the role of China. China plays a critical role in
the rapidly expanding intra-Asian trade as an assembly and production
center that supplies final goods for the advanced economies. However,
China’s trade shares in final goods with East Asia and in parts and
components with Europe and the USA are rising, suggesting that the
region’s production chains are becoming increasingly integrated into
the global business network. Empirical results from a panel vector
autoregression model generally confirm increasingly mutual
macroeconomic interdependence among East Asia, Europe and the USA. The
findings suggest a future role for Asia as an important trade partner
and balancing power in the world economy.
UT WOS:000287037500002
SN 1671-2234
doi 10.1111/j.1749-124X.2011.01225.x

Publication type J
Author/s Lam, C Rojo, F Dolendo, MC
Vol 56
Issue 6
Start page 935
End page 935
Publication year 2011
Times cited 0
UT WOS:000288463100139
SN 1545-5009

Publication type J
Author/s Roa, M
Vol 56
Issue 6
Start page 945
End page 945
Publication year 2011
Times cited 0
UT WOS:000288463100174
SN 1545-5009

Publication type J
Author/s Foronda, TF
Vol 19
Issue 2
Start page A23
End page A23
Publication year 2011
Times cited 0
UT WOS:000287878100062
SN 1067-1927

Publication type J
Title Filipino Arts Among Elders in Institutionalized Care Settings
Author/s de Guzman, AB Satuito, JCB Satumba, MAE Segui, DRA Serquina, FEC Serrano, LJP Sevilla, MD
Vol 37
Issue 3
Start page 248
End page 261
Publication year 2011
Times cited 0
Abstract The use of traditional art in recreational therapies is unexplored.
This paper, thus, attempts to surface the unique power of traditional
Filipino arts (TFA) as synergizing lens in capturing the individual and
the collective experiences of a select group of Filipino elderly in an
institutionalized care setting relative to their feelings of depression
and self-esteem. Three Filipino elderly housed in an institutionalized
care setting were chosen for this phenomenological study, a robotfoto
and a series of semistructured interviews constitute the main data
gathering tool. Field texts were subjected to phenomenological
reduction via the repertory grid analysis. Emerged themes were
subjected to a series of member checking procedures to ensure the
trustworthiness of the reported data. Depression and self-esteem were
interpreted via two emerged themes. The themes were Me, Myself, and
Melancholy and Will Not Let My Worth Wither. Through recreational
therapies in the form of traditional Filipino arts, participants found
novel psychological crutches that overcame the challenges of depression
and give them hope toward more positive views of themselves and life.
UT WOS:000287317900005
SN 0360-1277
doi 10.1080/03601270903534937

Publication type J
Title Evaluation of African Cultivated Rice Oryza glaberrima for Resistance
to Bacterial Blight
Author/s Djedatin, G Ndjiondjop, MN Mathieu, T Cruz, CMV Sanni, A Ghesquiere, A Verdier, V
Journal source PLANT DISEASE
Vol 95
Issue 4
Start page 441
End page 447
Publication year 2011
Times cited 0
Abstract Xanthomonas oryzae pv. oryzae is the causal agent of bacterial blight
in rice, one of the most devastating diseases of rice worldwide.
African X. oryzae pv. oryzae strains belong to a clear genetic group
distinct from those of Asia. Three new races of the pathogen were
characterized among strains from West Africa. We evaluated 107 Oryza
glaberrima accessions for resistance to bacterial blight under
greenhouse conditions. Six-week-old seedlings were inoculated with five
different African X. oryzae pv. oryzae strains originating from the
West African nations of Burkina and Mali and representing different
races (A1, A2, and A3). Philippine X. oryzae pv. oryzae strain PXO86
(race 2) was also used. Most (48%) of the accessions of O. glaberrima
were highly susceptible to X. oryzae pv. oryzae strains from Burkina,
while 20 and 36 were resistant to X. oryzae pv. oryzae strains from
Mali and the Philippines, respectively. CAPS markers and dot blot
assays were used for detection of resistance genes xa5 and Xa21 from a
selected set of O. glaberrima accessions. Our results suggest that the
O. glaberrima germplasm contains a narrow genetic base for resistance
to X. oryzae pv. oryzae. Sources of resistance identified among O.
glaberrima are recommended for rice breeding programs to develop
bacterial blight-resistant cultivars for West Africa.
UT WOS:000288728200011
SN 0191-2917
doi 10.1094/PDIS-08-10-0558

Publication type J
Title Immunogenicity, reactogenicity and safety of the human rotavirus
vaccine RIX4414 (Rotarix (TM)) oral suspension (liquid formulation)
when co-administered with expanded program on immunization (EPI)
vaccines in Vietnam and the Philippines in 2006-2007
Author/s Anh, DD Carlos, CC Thiem, DV Hutagalung, Y Gatchalian, S Bock, HL Smolenov, I Suryakiran, PV Han, HH
Journal source VACCINE
Vol 29
Issue 11
Start page 2029
End page 2036
Publication year 2011
Times cited 0
Abstract Evaluation of immunogenicity and safety of a 2-dose liquid formulation
of human rotavirus vaccine, RIX4414 following WHO’s Expanded Program on
Immunization (EPI) schedule (0, 1, and 2 months; Month 0 indicates day
of enrolment) in Vietnam and the Philippines. Infants aged 6-10 (mean =
8.7 +/- 1.07 weeks Vietnam) and 5-10 weeks (mean = 6.6 +/- 1.03 weeks
Philippines) received two doses of RIX4414 vaccine (V) and one dose of
placebo (PL) or three placebo doses concomitantly with commercially
available diphtheria-tetanus-whole-cell pertussis, hepatitis B and oral
poliovirus vaccines. The vaccination schedules were: V-V-PL, V-PL-V and
PL-PL-PL (Vietnam); PL-V-V, V-PL-V and PL-PL-PL (Philippines).
Anti-rotavirus seroconversion rate was assessed pre-vaccination and
post-vaccination (ELISA cut-off = 20 U/ml). 375 infants were enrolled
in each country. Seroconversion rates at one month post-Dose 2 of
RIX4414 were Vietnam 63.3% (95% CI: 54.3-71.6) in V-V-PL group and
81.5% (95% CI: 73.4-88) in V-PL-V group; Philippines 70% (95% CI:
61-78) in PL-V-V group and 59.2% (95% CI: 49.8-68) in V-PL-V group.
Frequencies of solicited (8-day post-each dose) and unsolicited
symptoms (31-day post-each dose) were similar. Two-doses of rotavirus
vaccine administered within the WHO EPI offer flexibility in existing
schedule, though both schedules provides good immune responses. (C)
2011 Elsevier Ltd. All rights reserved.
UT WOS:000288731000008
SN 0264-410X
doi 10.1016/j.vaccine.2011.01.018

Publication type J
Title At Arms’ Length Revisited: Why Radial Makes Even More Sense
Author/s Heuser, R
Vol 77
Issue 5
Start page 648
End page 648
Publication year 2011
Times cited 0
UT WOS:000288793200012
SN 1522-1946
doi 10.1002/ccd.23070

Publication type J
Title Gender and Physical Punishment: The Filipino Children’s Experience
Author/s Sanapo, MS Nakamura, Y
Vol 20
Issue 1
Start page 39
End page 56
Publication year 2011
Times cited 1
Abstract This paper reports selected findings from a doctoral dissertation on
Filipino children’s attitudes towards physical punishment. The findings
of this research stem from a survey of 270 grade-six students in
Iloilo, Philippines. The results indicated that the majority (61.1%)
had experienced physical punishment at home. The most common punishment
children received was pinching (74.5%), followed by beatings (49.7%).
The chi-square analysis revealed that more boys than girls were
physically punished (p < 0.05). Mothers were found to be the most
frequent users of physical punishment. The prevalence of physical
punishment at home may be attributed to Philippine law which ‘allows
parents to physically punish their children as may be necessary for the
formation of his good character’ as reflected in Article 45 of
Presidential Decree No. 603, known as ‘The Child and Youth Welfare
Code’ (Article 45, PD 603). The tendency of Filipino parents to punish
sons more harshly than their daughters could be explained in relation
to how boys and girls are regarded in society. Boys are expected to be
tough and brave. By administering harsher discipline, parents may
believe they are moulding their sons to be strong and to prepare them
to be future pillars of society. Copyright (C) 2010 John Wiley & Sons,
UT WOS:000287540100003
SN 0952-9136
doi 10.1002/car.1148

Publication type J
Title Extreme weather events and related disasters in the Philippines,
2004-08: a sign of what climate change will mean?
Author/s Yumul, GP Cruz, NA Servando, NT Dimalanta, CB
Journal source DISASTERS
Vol 35
Issue 2
Start page 362
End page 382
Publication year 2011
Times cited 1
Abstract Being an archipelagic nation, the Philippines is susceptible and
vulnerable to the ill-effects of weather-related hazards. Extreme
weather events, which include tropical cyclones, monsoon rains and dry
spells, have triggered hazards (such as floods and landslides) that
have turned into disasters. Financial resources that were meant for
development and social services have had to be diverted in response,
addressing the destruction caused by calamities that beset different
regions of the country. Changing climatic patterns and weather-related
occurrences over the past five years (2004-08) may serve as an
indicator of what climate change will mean for the country. Early
recognition of this possibility and the implementation of appropriate
action and measures, through disaster risk management, are important if
loss of life and property is to be minimised, if not totally
eradicated. This is a matter of urgent concern given the geographical
location and geological characteristics of the Philippines.
UT WOS:000287448400005
SN 0361-3666
doi 10.1111/j.0361-3666.2010.01216.x

Publication type J
Title Exploitation-related reef fish species richness depletion in the
epicenter of marine biodiversity
Author/s Nanola, CL Alino, PM Carpenter, KE
Vol 90
Issue 4
Start page 405
End page 420
Publication year 2011
Times cited 0
Abstract The central Visayan region of the Philippines historically has the
highest concentration of coral reef fishes than any other large marine
area in the world. This well-supported biogeographic phenomenon is
contradicted by recent transect observations on coral reefs that
indicates that the Visayan region and the southern Philippine Sea
region have the lowest species richness in the Philippines. The Visayan
region has unusually low counts of species typically exploited in
fisheries and the aquarium trade. This evidence, coupled with numerous
reports of intense fishing and habitat degradation and subsequent
species declines at local scales suggests that this exploitation is
having a cumulative effect on the overall species richness of the
Visayan region. Successes in Marine Protected Areas in this region in
increasing species richness at local scales suggests that improved
management of these protected areas coupled with much more intensive
fisheries management will be key to reviving a healthy biodiversity in
the Visayas.
UT WOS:000288512600007
SN 0378-1909
doi 10.1007/s10641-010-9750-6

Publication type J
Title Jatropha curcas oil body proteome and oleosins: L-form JcOle3 as a
potential phylogenetic marker
Author/s Popluechai, S Froissard, M Jolivet, P Breviario, D Gatehouse, AMR O’Donnell, AG Chardot, T Kohli, A
Vol 49
Issue 3
Start page 352
End page 356
Publication year 2011
Times cited 0
Abstract The seed oil of Jatropha curcas has been proposed as a source of
biodiesel. In plants, seed oil is stored in subcellular organelles
called oil bodies (OBs), which are stabilized by proteins. Proteome
composition of the J. curcas OBs revealed oleosins as the major
component and additional proteins similar to those in other oil seed
plants. Three J. curcas oleosins were isolated and characterized at the
gene, transcript and protein level. They all contained the
characteristic proline knot domain and were each present as a single
copy in the genome. The smallest, L-form JcOle3 contained an intron.
Isolation of its promoter revealed seed-specific cis-regulatory motifs
among others. Spatio-temporal transcript expression of J. curcas
oleosins was largely similar to that in other oil seed plants.
Immunoassay with antibodies against an Arabidopsis oleosin or against
JcOle3, on seed proteins extracted by different approaches, revealed
JcOle3 oligomers. Alleles of JcOle3 and single nucleotide polymorphisms
(SNPs) in its intron were identified in J. curcas accessions, species
and hybrids. Identified alleles and SNPs could serve as markers in
phylogenetic or breeding studies. (C) 2010 Elsevier Masson SAS. All
rights reserved.
UT WOS:000288777300016
SN 0981-9428
doi 10.1016/j.plaphy.2010.12.003

Publication type J
Title Systematics and phylogeny of the hoplonemertean genus Diplomma
(Nemertea) based on molecular and morphological evidence
Author/s Kajihara, H Olympia, M Kobayashi, N Katoh, T Chen, HX Strand, M Sundberg, P
Vol 161
Issue 4
Start page 695
End page 722
Publication year 2011
Times cited 0
Abstract We provide a redescription of the poorly known distromatonemertean,
Diplomma serpentina ( Stimpson, 1855), a species that has not been
reported since its original description. One of the freshly obtained
topotypes is designated as a neotype. Based on examination of the new
material, as well as the type specimens of three known species, we
present a taxonomic revision of the so-far monotypic genus Diplomma
Stimpson, 1857, which has been regarded as a dubious taxon since 1904.
The following three nominal species are transferred to Diplomma:
Paramphiporus albimarginatus Kirsteuer, 1965, Poseidonemertes
bothwellae Gibson, 1982, and Correanemertes polyophthalma Gibson &
Sundberg, 2001. The genus Paramphiporus Kirsteuer, 1965 is regarded as
a junior synonym of Diplomma. Comparison of cytochrome c oxidase
subunit I gene ( COI) sequences indicates that D. serpentina is
distributed in Indonesia, the Philippines, and Japan. Phylogenetic
analyses based on partial sequences of nuclear 28S rRNA and 18S rRNA
genes, as well as COI, from a selected number of distromatonemerteans
fail to specify the sister relation to Diplomma, although it is
suggested that the genus is more closely related to Antarctonemertes,
Gononemertes, Nemertellina, Tetraneuronemertes, Oerstedia, and
Vulcanonemertes, than to Amphiporus, Cyanophthalma, Geonemertes,
Malacobdella, Paranemertes, Poseidonemertes, Prostoma, Tetrastemma, and
Zygonemertes. (C) 2011 The Linnean Society of London, Zoological
Journal of the Linnean Society, 2011, 161, 695-722.
UT WOS:000288677700001
SN 0024-4082
doi 10.1111/j.1096-3642.2010.00650.x

Publication type J
Title Domestication of the mud crab Scylla serrata
Author/s Quinitio, ET de la Cruz, JJ Eguia, MRR Parado-Estepa, FD Pates, G Lavilla-Pitogo, CR
Vol 19
Issue 2
Start page 237
End page 250
Publication year 2011
Times cited 0
Abstract The significant decrease in wild mud crab population highlights the
need to manage the resources and domesticate crabs. This paper presents
the initial results of the domestication of mud crab Scylla serrata
aimed at producing good-quality captive broodstock. The analysis of the
genetic structure of the base population was done as a prerequisite for
domestication. Adult S. serrata from the northern to southern parts of
the Philippines (Cagayan, Camarines, Samar, and Surigao) were obtained
for genetic diversity analysis and domestication. Analysis of molecular
variance showed that differences in the genetic variability between the
four populations were not significant. Moreover, no significant
deviation from Hardy-Weinberg Equilibrium was observed in each sample
population and even in pooled populations. Body weight was positively
correlated with the carapace width. Second spawning occurred 41-46 days
after the first spawning and 34 days from second to third spawning.
However, there was a decrease in the number of zoea in repeat
spawnings. Twenty-four first-generation (F-1) families were produced
from the four sites. The duration from spawning of the base population
(P-0) to attainment of broodstock size F-1 was 10-14 months. Four
second-generation (F-2) families were produced after 11-12 months. Up
to the F-2, crabs tested negative for six viruses: white spot syndrome
virus, infectious hypodermal and hematopoietic necrosis virus,
gill-associated virus, yellow head virus, Taura syndrome virus, and
infectious myonecrosis virus. The reproductive performance of P-0 was
comparable to the succeeding generations. Several families were
obtained from one population in a year. However, due to the
cannibalistic behavior of crabs, more space is required for the nursery
and grow-out phase. The domestication of S. serrata is the first study
done on any mud crab species in the Indo-west Pacific region. The
initial results would serve as guide to understand and eliminate the
barriers to mud crab domestication. The breeding technology developed
from this study will support the production of good-quality seedstock
for farming.
UT WOS:000288795700003
SN 0967-6120
doi 10.1007/s10499-010-9381-0

Publication type J
Title Phenotypic differences between hatchery-reared and wild mud crabs,
Scylla Serrata, and the effects of conditioning
Author/s Parkes, L Quinitio, ET Le Vay, L
Vol 19
Issue 2
Start page 361
End page 380
Publication year 2011
Times cited 0
Abstract Hatchery-reared animals for stock enhancement should be competent to
survive and grow at rates equivalent to those of wild conspecifics.
However, morphological differences are often observed, and
pre-conditioning steps may be required to improve the fitness of
hatchery-reared juveniles prior to release. In the present study,
hatchery-reared Scylla serrata juveniles were reared either
individually (HR-solitary) or groups in tanks (HR-communal), the latter
group being exposed to intraspecific competition and foraging for food.
After 21 days, both groups were compared to similar size wild-caught
juveniles in terms of morphometric measurements of carapace spination,
abnormalities and carapace colouration. There were some limited
significant differences between HR-communal crabs and HR-solitary crabs
in terms of length of 8th and 9th lateral spines and in
body-weight-carapace width ratio, but both treatments differed from
wild crabs, which were heavier and had longer carapace spines for their
size. In contrast, both HR treatments exhibited common abnormalities
including deformities in the shape of the abdomen, in particular
occurrence of an asymmetrical telson or a deeply folded telson. In all
cases, abnormalities persisted through moulting. Initially, carapace
colour differed in all measures of colour between HR and wild crabs.
However, these differences reduced after a period of 4-8 days of
conditioning on coloured tank backgrounds or dark sand or mud
backgrounds, without moulting. Similarly, hatchery-reared crabs
exhibited very limited burying behaviour on first exposure to sediment,
but this increased to levels observed in wild crabs within 2-4 days.
Thus, short-term conditioning of hatchery-reared crabs on dark
sediments may be effective in increasing predator avoidance and
survivorship in released animals, and present results suggest that this
can be achieved after relatively short periods of 1 week or less.
UT WOS:000288795700012
SN 0967-6120
doi 10.1007/s10499-010-9372-1

Publication type J
Title Workplace Discourse
Author/s Valdez, PNM
Vol 25
Issue 2
Start page 237
End page 241
Publication year 2011
Times cited 0
UT WOS:000287796500005
SN 1050-6519
doi 10.1177/1050651910390769

Publication type J
Title An extended graphical targeting technique for direct reuse/recycle in
concentration and property-based resource conservation networks
Author/s Saw, SY Lee, L Lim, MH Foo, DCY Chew, IML Tan, RR Klemes, JJ
Vol 13
Issue 2
Start page 347
End page 357
Publication year 2011
Times cited 0
Abstract Minimum flowrate targeting methods for resource conservation networks
(RCNs) have been developed over the last decades. The existing
methodologies still have certain drawbacks. Their design insights could
be deepened and some steps should be more convenient for the users. A
targeting tool called the material surplus composite curve (MSCC),
which is an improvement of the surplus diagram for water and hydrogen
networks is introduced. The approach is illustrated on several cases
selected from the literature. Using this technique, it is possible to
determine rigorous flowrate targets for different variants of the RCN
UT WOS:000288549400010
SN 1618-954X
doi 10.1007/s10098-010-0305-5

Publication type J
Title Enhanced biodiversity beyond marine reserve boundaries: The cup
spillith over
Author/s Russ, GR Alcala, AC
Vol 21
Issue 1
Start page 241
End page 250
Publication year 2011
Times cited 0
Abstract Overfishing can have detrimental effects on marine biodiversity and the
structure of marine ecosystems. No-take marine reserves (NTMRs) are
much advocated as a means of protecting biodiversity and ecosystem
structure from overharvest. In contrast to terrestrial protected areas,
NTMRs are not only expected to conserve or recover biodiversity and
ecosystems within their boundaries, but also to enhance biodiversity
beyond their boundaries by exporting species richness and more complex
biological communities. Here we show that species richness of large
predatory reef fish increased fourfold and 11-fold inside two
Philippine no-take marine reserves over 14 and 25 years, respectively.
Outside one reserve (Apo) the species richness also increased. This
increase beyond the Apo reserve boundary was 78% higher closer to the
boundary (200-250 m) than farther from it (250-500 m). The increase in
richness beyond the boundary could not be explained by improvements
over time in habitat or prey availability. Furthermore, community
composition of predatory fish outside but close to (200-250 m) the Apo
reserve became very similar to that inside the reserve over time,
almost converging with it in multivariate space after 26 years of
reserve protection. This is consistent with the suggestion that, as
community composition inside Apo reserve increased in complexity, this
complexity spilled over the boundary into nearby fished areas. Clearly,
the spillover of species richness and community complexity is a direct
consequence of the spillover of abundance of multiple species. However,
this spillover of species richness and community complexity
demonstrates an important benefit of biodiversity and ecosystem export
from reserves, and it provides hope that reserves can help to reverse
the decline of marine ecosystems and biodiversity.
UT WOS:000288850200020
SN 1051-0761

Publication type J
Title Intergroup Positioning in the Political Sphere: Contesting the Social
Meaning of a Peace Agreement
Author/s Montiel, CJ de Guzman, J
Vol 41
Issue 1
Start page 92
End page +
Publication year 2011
Times cited 0
Abstract Cristina Jayme Montiel and Judith de Guzman, Intergroup Positioning in
the Political Sphere: Contesting the Social Meaning of a Peace
Agreement, pp. 92-116
Using a positioning theory lens, we investigated contentious intergroup
conversations about a peace agreement called the Memorandum of
Agreement (MOA), between the Government of the Republic of the
Philippines (GRP) and the Moro Islamic Liberation Front (MILF). Our
data pool consisted of 220 articles from newspaper and government/MILF
website sources. We identified a variety of changing storylines,
identities, rights and duties, and social forces of speech and
non-speech acts. We discovered that the meaning of a peace agreement
(a) varies across different political groups; (b) changes across time,
as the public debate intensifies; (c) and may morph to discourses about
group victimization and negative collective identities of the low-power
group during conflict escalation. Our findings also suggest that a
wider sequential lens during intergroup political conversations may
reveal episodes where avenues for social justice for the low-power
group are blocked, and are then followed by eruptions of so-called
terrorist acts.
UT WOS:000287493200005
SN 0021-8308

Publication type J
Title Single-Port Compared With Conventional Laparoscopic-Assisted Vaginal
Hysterectomy A Randomized Controlled Trial
Author/s Chen, YJ Wang, PH Ocampo, EJ Twu, NF Yen, MS Chao, KC
Vol 117
Issue 4
Start page 906
End page 912
Publication year 2011
Times cited 0
Abstract OBJECTIVE: To compare the immediate results of patients undergoing
either two-channel single-port laparoscopic-assisted vaginal
hysterectomy or conventional multiport laparoscopic-assisted vaginal
METHODS: Patients were randomly assigned to undergo
laparoscopic-assisted vaginal hysterectomy using the single-port (n=50)
or conventional (n=50) approach. The outcome measures included blood
loss, operative time, intraoperative and immediate postoperative
complications, time to flatus passage after operation, and
postoperative pain (assessed by the visual analog scale score and
postoperative analgesics use).
RESULTS: The general characteristics of the patients were similar in
both groups. There were no statistically significant differences in
operative time, estimated blood loss, time to first flatus,
intraoperative and immediate postoperative complications, shoulder tip
pain, or length of hospital stay between the two groups. However,
postoperative pain was significantly less in the single-port group
compared with the conventional group, as evidenced by lower mean scores
on the visual analog scale (3.64 +/- 2.75 compared with 5.08 +/- 2.76
at 24 hours, P=.011 and 1.94 +/- 2.31 compared with 2.84 +/- 2.07 at 48
hours, P=.043) and less mean accumulated dose of postoperative
analgesics (74.40 +/- 24.25 mg compared with 104.80 +/- 57.08 mg of
meperidine, P=.001; 16 +/- 13.40 mg compared with 33.6 +/- 28.7 mg of
tenoxicam, P <.001).
CONCLUSION: Transumbilical two-channel single-port
laparoscopic-assisted vaginal hysterectomy significantly decreases
postoperative pain and analgesic use.
UT WOS:000288647500022
SN 0029-7844
doi 10.1097/AOG.0b013e31820c666a

Publication type J
Author/s Lanuza, GM
Vol 40
Issue 1
Start page 14
End page 40
Publication year 2011
Times cited 0
Abstract Richard Rorty, a world-renowned American pragmatist, died on 8 June
2007. He left an enduring impact on Western philosophy. Like his
predecessors Nietzsche, Dewey, Wittgenstein, and Derrida, Rorty
attempted the gargantuan task of redescribing the nature of philosophy
in the late twentieth century. This article is a modest personal
tribute to a great philosopher who shaped the author’s views about
self-creation, metaphysics, and politics. The major themes in Rorty’s
philosophy are discussed briefly. It is the author’s hope that this
article will serve as a short introduction to Rorty’s. neopragmatism.
The author likewise hopes that it will stimulate the readers to pursue
the philosophical issues that Rorty raised.
UT WOS:000287428800003
SN 0115-8988

Publication type J
Author/s Mabaquiao, NM
Vol 40
Issue 1
Start page 76
End page 87
Publication year 2011
Times cited 0
Abstract Critical in the computationalist account of the mind is the phenomenon
called computational or computer simulation of human thinking, which is
used to establish the theses that human thinking is a computational
process and that computing machines are thinking systems. Accordingly,
if human thinking can be simulated computationally then human thinking
is a computational process; and if human thinking is a computational
process then its computational simulation is itself a thinking process.
This paper shows that the said phenomenon-the computational simulation
of human thinking-is ill-conceived, and that, as a consequence, the
theses that it intends to establish are problematic. It is argued that
what is simulated computationally is not human thinking as such but
merely its behavioral manifestations; and that a computational
simulation of these behavioral manifestations does not necessarily
establish that human thinking is computational, as it is logically
possible for a non-computational system to exhibit behaviors that lend
themselves to a computational simulation.
UT WOS:000287428800007
SN 0115-8988

Publication type J
Title Hobbes: Prince of peace
Author/s Vanhoutte, W
Vol 40
Issue 1
Start page 107
End page 110
Publication year 2011
Times cited 0
UT WOS:000287428800010
SN 0115-8988

Publication type J
Title Understanding Predictors of Postdischarge Deaths: A Prospective
Evaluation of Children 5 Years and Younger Discharged From Philippine
District Hospitals
Author/s Panelo, CIA Shimkhada, R Solon, OC Quimbo, SA Florentino, JF Peabody, JW
Vol 23
Issue 2
Start page 133
End page 140
Publication year 2011
Times cited 0
Abstract Background. Factors that increase likelihood of readmission or
mortality postdischarge from diarrhea and pneumonia cases among
children is less understood. Methods. This study investigated the
deaths of 24 children from a cohort of 3275. Using logistic regression,
the authors compared data from those who survived with those who died
to estimate the determinants of mortality in the study population. The
authors also analyzed the hospital charts and completed mortality
interviews with families of the deceased children. Results. Poor
quality of care significantly increased the likelihood of mortality.
Sicker children, those born to less-educated mothers, and those who had
longer lengths of stay also had a higher likelihood of mortality.
Hospital charts corroborated findings from clinical vignettes. The
mortality interviews revealed delays in seeking care from onset of
symptoms. Conclusion. Quality of care contributes to postdischarge
mortality and that clinical vignettes are an effective means to
identify where quality can be improved.
UT WOS:000288407500003
SN 1010-5395
doi 10.1177/1010539509342120

Publication type J
Title Improving High School Students’ Statistical Reasoning Skills: A Case of
Applying Anchored Instruction
Author/s Prado, MM Gravoso, RS
Vol 20
Issue 1
Start page 61
End page 72
Publication year 2011
Times cited 0
Abstract A learning unit was developed on Binomial Distribution, Poisson
Distribution and Normal Distribution by working alongside with the
statistics teacher and professors and using the statistics textbook,.
Titled Mark’s Eco-encounter, the learning unit was composed of a video
that presented the challenge and activity guide that provided synopsis
of the story, formulae, and other information needed to solve the
challenge. The fictitious story revolved around high school students
who participated in a national environmental camp. The task of the
class was to help the main characters in the story, Mark, Ann and Lui,
solve the problems that they encounter. The instructional intervention
was implemented for three weeks. Comparing respondents’ incremental
scores, data showed a highly significant difference between the
students who studied using the anchored instruction and the
teacher-centered in their statistical reasoning skills in traditional
word and authentic problems related to Binomial, Normal and Poisson
Distribution. Based on the students’ feedback, Mark’s Eco-encounter
made their class interesting and interactive, enabled them to study
involving realistic situation, motivated them to learn on their own,
promoted collaboration, allowed them to learn about environment aside
from statistics, provided them episodic memory cues, and changed their
perception of statistics. The students also said that they like the new
approach in learning compared to their usual statistics class.
UT WOS:000287641300005
SN 0119-5646

Publication type J
Title Critical Thinking, Negative Academic Emotions, and Achievement: A
Mediational Analysis
Author/s Villavicencio, FT
Vol 20
Issue 1
Start page 118
End page 126
Publication year 2011
Times cited 0
Abstract The study tested the control-value theory’s (Pekrun, 2006; Pekrun,
Goetz, Titz, & Perry, 2002) assumptions regarding the
cognitive-motivational effects of emotions on achievement.
Specifically, the link between critical thinking and achievement was
examined among 220 engineering students. The Academic Emotions
Questionnaire (Pekrun, Goetz, & Frenzel, 2005) was used to assess how
specific negative academic emotions mediated the effect of critical
thinking on achievement. Results showed that critical thinking was
positively associated with achievement, but negative emotions (anger,
anxiety, shame, boredom, and hopelessness) were negatively correlated
with achievement. Anxiety and hopelessness were found to completely
mediate the relationship between critical thinking and academic
achievement. The results suggested that when students engage in
critical thinking, their cognitive resources are used appropriately for
the task to be completed, making them less anxious and less hopeless,
thereby increasing their achievement.
UT WOS:000287641300009
SN 0119-5646

Publication type J
Title Motivational Antecedents of Academic Emotions in Filipino College
Author/s Ouano, JA
Vol 20
Issue 1
Start page 127
End page 132
Publication year 2011
Times cited 0
Abstract The control-value theory of academic emotions by Pekrun (2006) contends
that students’ emotional experiences in achievement-related situations
have sources from the appraisals students make about the importance and
value of academic tasks they engage in. The present study looked into
Filipino students’ structure of academic emotions, as well as intrinsic
and extrinsic motivation as antecedents of academic emotions, upon the
assumption that students’ motivations are shaped by their appraisals of
importance and value of schooling. Results showed that intrinsic
motivation had a positive predictive utility on positive emotions but
negatively associated with any negative types of emotions. Extrinsic
motivation positively predicted negative emotions. The predictive
utility of the specific dimensions of intrinsic and extrinsic
motivation on academic emotions were also analyzed, and results
supported most of the hypotheses.
UT WOS:000287641300010
SN 0119-5646

Publication type J
Title Hoya ilagii, another new species (Apocynaceae, Asclepiadoideae) from
Luzon Island, Philippines
Author/s Kloppenburg, RD Siar, SV Carandang, JM Hadsall, AS
Vol 20
Issue 2
Start page 263
End page 269
Publication year 2011
Times cited 0
Abstract A new species of Hoya R.Br. (Apocynaceae, Asclepiadoideae), Hoya ilagii
Kloppenburg, Siar & Cajano is described and illustrated. This new
species is endemic to Mt. Mabilog situated in Nagcarlan, Laguna on
Luzon Island, Philippines. The relationship of this new species to H.
crassicaulis Elmer ex Kloppenburg is discussed and a full taxonomic
description, together with detailed illustration is provided.
UT WOS:000288522000001
SN 0117-3375

Publication type J
Title Developmental historicity and saccharide heterotrophy of Schizochytrium
sp OT01: Implication of docosahexaenoic acid production for
biotechnological applications
Author/s Batbatan, CG Hepowit, NL Oclarit, JM
Vol 20
Issue 2
Start page 289
End page 305
Publication year 2011
Times cited 0
Abstract Thraustochytrids have been targeted worldwide in search of highly
oleaginous strains for industrial applications and newly collected
holotypes are described based on life cycle developmental history and
saccharide heterotrophy. Schizochytrium sp. OT01, a novel
thraustochytrid protist from Panay, Philippines, distinguished from
other reported strains by its asexual reproductive history – including
the successive binary division of vegetative cells forming tetrads or
octads, granular maturation of thalli into zoosporangia liberating
heterokont motile zoospores and transformation of spheroidal thalli
into amoeboid cells. Live-cell differential imaging and electron
micrographs support its distinctive morphological features, such as
hair-like pseudopodial astrals along hyaline margins of mature
limaciform amoeboids and in motile zoospores prior to heterokont
flagellum elongation. Moreover, its heterotrophic culture on certain
saccharides (glucose, fructose, cellobiose, sucrose and starch) in
continuously agitated fermentation condition was further investigated
to determine hydrocarbon assimilative profiles as deduced from biomass
yield and polyunsaturated fatty acid production. Increasing biomass
yield was observed in increasing concentrations of saccharides;
however, aside from glucose and fructose, a graphical drop of biomass
was apparent beyond 15 gL, implying osmotic stress at these levels.
Maximum biomass yield was observed at 30 gL(-) glucose and fructose
concentration, reaching to about 6 g/l as expressed in freeze-dried
weight of harvested cells, which indicates that OT01 could efficiently
absorb and metabolize glucose and fructose compared to other
hydrocarbons with relatively greater molecular weights. Even though
biomass yield amounts were relatively low in cellobiose, sucrose and
starch; however, docosahexaenoic acid (DHA) content in total fatty
acids was relatively higher, amounting to 45.23, 46.25 and 48.86%,
respectively. Moreover, oleagineity levels in glucose and fructose were
highest, with lipid yield amounting to 655.55 and 609.38 mg,
respectively, in every gram of freeze-dried weight cells. Consequently,
DHA yield was significantly higher in both glucose and fructose,
reaching respectively to 492.04 and 478.18 mg per liter of nutrient
broth, which indicates higher absorption and metabolism efficiency of
monosaccharides into fatty acids.
UT WOS:000288522000003
SN 0117-3375

Publication type J
Title Cancer chemotherapeutic potential of endemic and indigenous plants of
Kanawan, Morong, Bataan Province, Philippines
Author/s Canoy, RJC Lomanta, JMJC Ballesteros, PM Chun, EAC Dator, RP Jacinto, SD
Vol 20
Issue 2
Start page 331
End page 339
Publication year 2011
Times cited 0
Abstract The medicinal properties of some endemic and indigenous plants from the
ancestral domain of the Aytas, a group of indigenous people of Kanawan,
Morong, Bataan Province, Philippines were investigated. One focus of
the study was ‘anticancer property. Crude ethanolic extracts of leaves
were evaluated for cytotoxicity against two human cancer cell lines:
lung non-small cell adenocarcinoma (A549) and colon carcinoma (HCT
116). Cytotoxicity was determined using an assay for the reduction of
the yellow tetrazolium (MTT) into purple formazan. Among the 15 plant
species tested, crude extracts of Aglaia loheri Blanco (Meliaceae),
Ficus septica Burm. (Moraceae) and Voacanga globosa (Blanco) Merr.
(Apocynaceae) exhibited high toxicity against the two cell lines with
IC50 values below 201 g/mL. These extracts were subsequently
partitioned into ethyl acetate and hexane fractions and tested again
for cytotoxicity. The resulting ethyl acetate fractions exhibited lower
IC50 values compared to the crude extracts, indicating that these are
worth pursuing for further purification of active components.
UT WOS:000288522000006
SN 0117-3375

Publication type J
Title In vitro digestibility study of mungbean [Vigna radiata (L.) Wilczek]
Author/s Gatchalian-Yee, MV
Vol 20
Issue 2
Start page 341
End page 359
Publication year 2011
Times cited 0
Abstract A study was conducted to investigate in vitro protein digestibility of
mungbean, Vigna radiata (L.) Wilzeck. Whole and dehulled mungbean
samples were boiled or autoclaved at 0, 10, 30, 50 min. A multi-enzyme
technique by Hsu et al. (1977) was used. Trypsin, chymotrypsin and
peptidase were the enzymes which determined the in vitro digestibility
of the mungbean samples. Results showed an increased in percentage in
vitro digestibility as length of cooking time of mungbean samples
increased. Also, whole mungbean samples boiled at 30 min were
recommended for household use.
UT WOS:000288522000007
SN 0117-3375

Publication type J
Title Revised size limit for viability in the wild: Neonatal and young of the
year whale sharks identified in the Philippines
Author/s Aca, EQ Schmidt, JV
Vol 20
Issue 2
Start page 361
End page 368
Publication year 2011
Times cited 0
Abstract The whale shark, Rhincodon typus, is a vulnerable species found in
tropical waters worldwide. Young whale sharks are rarely seen, with
only 12 encounters with neonatal animals reported in the scientific
literature. During March 2009, two neonatal whale sharks were recovered
alive near Donsol, Philippines, the first neonatal whale sharks
identified in the western Pacific. The first animal measured 46 cm
total length, and the second measured 64 cm total length, and both
sharks carried the abdominal vitelline scars indicative of recent
pupping. The 46 cm neonate is the smallest free-swimming whale shark
ever recorded. Young of the year whale sharks between I and 2 m total
length are also very rare. A previously unreported juvenile whale shark
from the Philippines measuring 1.4 m total length is described here.
These findings significantly add to the limited body of knowledge of
whale sharks in their earliest free-swimming life stage.
UT WOS:000288522000008
SN 0117-3375

Publication type J
Title Leaf size zonation pattern of woody species along the northeastern
altitudinal gradient of Mount Makiling, Luzon Island, Philippines
Author/s Lambio, IAFBuot, IE
Vol 20
Issue 2
Start page 369
End page 383
Publication year 2011
Times cited 0
Abstract Woody species sampled along trail linking UPLB to the peak were
subjected to leaf size zonation study using cluster analysis from 150
to 950 meters above sea level (m asl) on the northeastern slopes of Mt.
Makiling (1109 m asl). Eighty species representing 64 genera and 36
families were encountered within the study area. Cluster analysis using
leaf size showed that four clusters existed: Zone I – mesophyllous and
notophyllous, Zone II – mesophyllous, notophyllous and microphyllous,
Zone III – mesophyllous and Zone IV – microphyllous. Largest leaf
measuring 132000 mm(2) belonged to the Moraceae family (Artocarpus
blancoi) and was collected at 250 m asl (Zone I), while the smallest
leaf measuring 47.2 mm(2) belonged to the family Sabiaceae (Meliosma
pinnata) and was collected at 450 masl (Zone I). Results show that
large leaf sizes are mostly found in lower elevations and are replaced
by smaller leaf sizes with increase in altitude; Emergence of a
distinct zone within the first zone, attributed to previous intentional
reforestation efforts of big-leafed exotic pioneer species and human
encroachment, leading to the increase in mesophyllous leaves.
UT WOS:000288522000009
SN 0117-3375

Publication type J
Title Tetragnatha heongi, a new species of long-jawed orb spider (Araneae:
Tetragnathidae:Tetragnathinae) from Hainan Island, China
Author/s Barrion, AT Barrion-Dupo, ALA Villareal, SS Cai, DC
Vol 20
Issue 2
Start page 385
End page 394
Publication year 2011
Times cited 0
Abstract Tetragnatha heongi Barrion & Barrion-Dupo, a new species of long-jawed
orb spider from Hainan Island, China is described and illustrated. It
belongs to the subfamily Tetragnathinae possessing long legs, slender
abdomen, and porrect chelicerae with strong promarginal and
retromarginal teeth and a member of the “rubriventris-group”
characterized by the posterior eye row (PER) distinctly narrower than
the anterior eye row (AER) and male chelicera as long as or longer than
carapace. It represents the 39(th) species described from China. A
biological note on phorid flies associated with the egg cocoon is also
UT WOS:000288522000010
SN 0117-3375

Publication type J
Title Changes in indigenous land use system: From swidden to sedentary
Author/s Palao, LKM Dressler, WH Cruz, RVO Pulhin, JM
Vol 20
Issue 2
Start page 395
End page 416
Publication year 2011
Times cited 0
Abstract As the Philippine government continues to embrace the establishment of
protected areas as a primary strategy for environmental conservation,
livelihood difficulties have arisen in marginal areas where land and
forest resources become scarce. This paper explores why the indigenous
Tagbanua people, who commonly practice shifting agriculture (or
swidden), are slowly moving towards sedentary agriculture due to
socio-political and economic pressures at Puerto Princesa Subterranean
River National Park, Palawan Island, the Philippines. A
semi-structured, open-ended questionnaire is used to explore the
factors that have given rise to this shift in land use production among
Tagbanua. The limitations of access to forest areas, programs of
government and non-government organizations, declining swidden
productivity and growth of local markets have caused Tagbanua to opt
for rice paddy and fruit farming. Current national park-related
interventions are directed towards stabilizing swidden to prevent
further expansion into the forest frontiers of buffer zones. Efforts
from government and non-governmental organization have brought
livelihood programs, dispersal of seedlings, draught animals, and
seminars and trainings to facilitate the sedentary farming of Tagbanua.
Currently, swidden is practiced as a means of land preparation for the
expansion and establishments of fruit plantations, paddy rice
cultivation and other intensified agriculture. However, this does not
suggest that swidden is completely in demise. Although agricultural
intensification is on the rise, swidden agriculture is still integrated
into Tagbanua livelihood strategies.
UT WOS:000288522000011
SN 0117-3375

Publication type J
Title Acetylcholinesterase (AChE) inhibition and changes in branchial
histology of Nile Tilapia (Oreochromis niloticus L.) as induced by
thiobencarb herbicide
Author/s Legaspi, DB Ocamp, PP
Vol 20
Issue 2
Start page 417
End page 429
Publication year 2011
Times cited 0
Abstract Three experiments (i.e. including dose-response, time-course and
recovery) were conducted to determine the effects of low concentration
levels of thiobencarb on acetylcholinesterase (AChE) activity and
branchial histology in Oreochromis niloticus L. The dose-response
experiment found that the brain AChE inhibition rate significantly
varied among treatment groups (KW= 21.6, p<0.05). On the other hand,
the enzyme inhibition rates of muscle samples of the same individuals
showed no significant trend among treatment groups with values ranging
from 72.4- 75.5%. These values were relatively higher than those
detected among brain samples. In the time-course experiment, where 50
fish were exposed to a constant dose (0.120 mg/L) of thiobencarb in
varying test period, found that those individuals with longer period of
exposure exhibited also higher rate of brain AChE inhibition. The
differences among exposure period were found significant (KW= 36.7,
p<0.05). The same pattern of activity was observed from muscle samples
obtained from the same individuals at different observation period (KW=
29.8, p<0.05). Recovery of either muscle or brain AChE activities was
also observed in all the treated individuals. In the dose-response
experiment, changes in branchial histology were also evaluated.
Hyperplasia was the apparent abnormality observed in all doses. The
presence and severity of gill lesions among thiobencarb-exposed fish
(i.e. including hyperplasia, wilting, clavate and aneurysm) were found
to be influenced by the increasing concentrations.
UT WOS:000288522000012
SN 0117-3375

Publication type J
Title Preservation of Culture Heritage through Philippine Games
Author/s Buan, AR Monte, RN dela Cruz, JS Salangsang, MTA
Vol 20
Issue 2
Start page 431
End page 442
Publication year 2011
Times cited 0
Abstract Philippine games are part of our cultural heritage that was once
popular but is now almost buried in oblivion. People have forgotten to
play these games hence, most children have taken their value for
granted as the social teaming process became broken. Children today
engage in desktop or hand-held computer games instead of playing
diverse array of traditional games. Displaced Philippine games, which
serve as socio-historical markers mean less appreciation of our culture
and its relationship with the environment-social and natural. The
rationale of this study is to help in the appreciation, preservation
and propagation of Philippine games. The traditional games are
presented in a new light that could give the youth a renewed outlook on
Philippine culture and environment consequently helps in preserving
this important facet of Filipino daily lives.
UT WOS:000288522000013
SN 0117-3375

Publication type J
Title Effects of controlled burning on soil erosion rates, survival and
growth of Pinus kesiya and Alnus japonica in Itogon, Benguet Province,
Author/s Florece, LM Tolentino, EL Bantayan, NC Cruz, RVO Castillo, ASA
Vol 20
Issue 2
Start page 491
End page 502
Publication year 2011
Times cited 0
Abstract The effects of controlled burning on survival and growth of newly
planted seedlings of Pinus insularis and Alnus japonica and soil
erosion rates of the burned and unburned plots were quantified in
Itogon, Benguet Province, Philippines.
The results showed that survival of the two species in the burned and
unburned plots was not significantly different. The overall mean
survival rate of trees in the burned plot was 93.8% compared to 93.1%
in the unburned. In terms of growth diameter as affected by fire, A.
japonica diameter increment was higher in the low fire intensity, while
for P insularis the diameter increment was higher in the unburned
treatment compared to the two fire intensity levels. The same responses
were also observed in the growth height of the two species.
Soil erosion rate in 2008 was high in the burned plot at 2.73 tha(-1)
and 0.73 tha(-1) for the unburned, while for 2009, the burned plot had
3.91 tha(-1) and 3.69 tha(-1) in the unburned. In terms of surface
runoff, the unburned had higher value at 69.9 m(3)ha(-1) compared to
63.6 m(3)ha(-1) for the burned plot in 2008, but in 2009, the burned
plot had higher surface runoff at 534.4 m(3)ha(-1) as against 529
m(3)ha(-1) in the unburned.
While the cost of reforestation using controlled burning is much higher
than the conventional reforestation approach, the use of fire to
eradicate fire hazard is promising for ecosystems where fire is part of
their natural development processes.
UT WOS:000288522000017
SN 0117-3375

Publication type J
Title Responses of yellow corn (Zea mays L.) inbreds to salinity
Author/s Magnaye, AMA Santos, PJA Cruz, PCS
Vol 20
Issue 2
Start page 521
End page 533
Publication year 2011
Times cited 0
Abstract Two greenhouse experiments were conducted to assess the responses of
yellow corn inbred lines to varying salt concentrations at early and
late vegetative stages using hydroponics culture. In the first
experiment, significant detrimental effects on young corn (Zea mays L.)
plants from 19 inbred lines were apparent in terms of plant height, dry
matter accumulation and survival when the plants were grown in saline
medium (100 mMol NaCl). In contrast, chlorophyll content in plants
generally increased under saline medium. Corn inbred lines varied in
the degree of response to saline condition. Inbred lines that exhibited
the highest tolerance and sensitivity to salt were advanced to the
second experiment. The second experiment showed similar plant responses
in terms of plant height, dry matter accumulation and survival when
grown under increasingly saline medium at late vegetative stage. The
tolerant inbred IYL-50 had the highest dry matter accumulation
regardless of salinity level, while IYL-44 had the lowest. However,
chlorophyll content also decreased with increasing salinity, in
contrast to the results obtained from the first experiment. The
inconsistency with the observation at early vegetative stage could be
due to re-mobilization of nitrogen from the leaves (affecting the
chlorophyll) as the plants shifted from vegetative to reproductive
stage. Results showed that corn plants are more susceptible to salinity
stress at early vegetative stage than at late vegetative to early
reproductive stage. While the corn plants were found to be generally
sensitive to salt stress, the observed differential degree of response
could be used as a basis in selecting possible parent materials to
develop salt tolerant corn varieties or hybrids.
UT WOS:000288522000019
SN 0117-3375

Publication type J
Title The Changing Face of Infective Endocarditis in the Adult Filipino: A
Six Year Review (2004-2009) at the Philippine General Hospital
Author/s Javier, AC Punzalan, FE Abelardo, NS Salvana, EM Leyritana, K
Vol 147
Start page S17
End page S18
Publication year 2011
Times cited 0
UT WOS:000288659000055
SN 0167-5273

Publication type J
Title Untreated Depressive Symptoms Among Cognitively-Intact, Community
Dwelling Filipino Patients With Parkinson Disease
Author/s Go, CL Rosales, RL Joya-Tanglao, M Fernandez, HH
Vol 121
Issue 3
Start page 137
End page 141
Publication year 2011
Times cited 0
Abstract The objective of this study is to determine the prevalence of
depressive symptoms and its correlation with the quality of life among
cognitively intact, community dwelling Filipino patients with Parkinson
disease (PD) not treated pharmacologically for depression. In this
prospective, cross-sectional study 76 PD patients were included.
Demographic data were obtained including: age, gender, onset of
disease, disease duration, and medication intake. The Mini Mental State
Examination (MMSE) was performed to exclude significant cognitive
impairment. The Montgomery Asberg Depression Rating Scale (MADRS) was
administered to quantify the degree of depressive symptoms. The degree
of depressive symptoms was correlated with the SF 36 and UPDRS Parts II
and III. Our cohort of patients had a mean age of 61 years (range:
42-81 years), and disease duration of 2.7 years (33 months); 46 (61%)
experienced significant depressive symptoms based on the MADRS cutoff
score of > 14. Depressive symptoms were associated with poorer
performance on both UPDRS Parts II and III and SF 36. Untreated
depressive symptoms among Filipinos with PD may be higher compared to
other PD populations but prospective and age-matched controlled studies
will need to be performed to confirm these preliminary observations.
The presence of depressive symptoms was significantly correlated with
poorer quality of life and level of functioning.
UT WOS:000288721300004
SN 0020-7454
doi 10.3109/00207454.2010.537414

Publication type J
Title Oceanic Sharks Clean at Coastal Seamount
Author/s Oliver, SP Hussey, NE Turner, JR Beckett, AJ
Journal source PLOS ONE
Vol 6
Issue 3
Publication year 2011
Times cited 0
Abstract Interactions between pelagic thresher sharks (Alopias pelagicus) and
cleaner wrasse were investigated at a seamount in the Philippines.
Cleaning associations between sharks and teleosts are poorly
understood, but the observable interactions seen at this site may
explain why these mainly oceanic sharks regularly venture into shallow
coastal waters where they are vulnerable to disturbance from human
activity. From 1,230 hours of observations recorded by remote video
camera between July 2005 and December 2009, 97 cleaner-thresher shark
events were analyzed, 19 of which were interrupted. Observations of
pelagic thresher sharks interacting with cleaners at the seamount were
recorded at all times of day but their frequency declined gradually
from morning until evening. Cleaners showed preferences for foraging on
specific areas of a thresher shark’s body. For all events combined,
cleaners were observed to conduct 2,757 inspections, of which 33.9%
took place on the shark’s pelvis, 23.3% on the pectoral fins, 22.3% on
the caudal fin, 8.6% on the body, 8.3% on the head, 2.1% on the dorsal
fin, and 1.5% on the gills respectively. Cleaners did not
preferentially inspect thresher sharks by time of day or by shark sex,
but there was a direct correlation between the amount of time a
thresher shark spent at a cleaning station and the number of
inspections it received. Thresher shark clients modified their behavior
by “circular-stance-swimming,” presumably to facilitate cleaner
inspections. The cleaner-thresher shark association reflected some of
the known behavioral trends in the cleaner-reef teleost system since
cleaners appeared to forage selectively on shark clients. Evidence is
mounting that in addition to acting as social refuges and foraging
grounds for large visiting marine predators, seamounts may also support
pelagic ecology by functioning as cleaning stations for oceanic sharks
and rays.
UT WOS:000288512400003
SN 1932-6203
doi 10.1371/journal.pone.0014755

Publication type J
Title 20-Year Trends in Filipino Women’s Weight Reflect Substantial Secular
and Age Effects
Author/s Adair, LS Gultiano, S Suchindran, C
Vol 141
Issue 4
Start page 667
End page 673
Publication year 2011
Times cited 0
Abstract Increasing obesity in low- and middle-income countries is well
documented in cross-sectional studies. However, few longitudinal
studies identify factors that influence individual weight gain patterns
over time in relation to the major social and economic changes that now
characterize these settings. This study uses data from adult Filipino
women participating in the Cebu Longitudinal Health and Nutrition
Survey from 1983 to 2005. A sample of 3005 women contributed 1-8
observations each. Longitudinal mixed effects models identified how age
and secular weight trends related to underlying effects of urbanization
and changing household socioeconomic status (SES) and to proximate
individual effects of reproductive history, diet, and occupational
physical activity. The 23-y secular trend in weight amounted to nearly
10 kg. Younger women gained more weight than older women (12.4 kg in
those < 20 y old in 1983 vs. 4.9 kg in those > 35 y). Periods of more
rapid weight gain corresponded to periods of rapid increase in SES and
urbanization. Weight was positively related to energy intake,
percentage of calories from protein, and more sedentary occupations,
but negatively related to months pregnant and lactating and
postmenopausal status. These effects all varied with age and over time.
The trends contributed to a 6-fold increase in prevalence of overweight
and an increasing number of women who have or are likely to develop
obesity-related metabolic diseases. The trends are highly relevant for
health policy and preventive health measures in the Philippines and
other countries now facing the dual burden of over- and undernutrition.
J. Nutr. 141: 667-673, 2011.
UT WOS:000288876800019
SN 0022-3166
doi 10.3945/jn.110.134387

Publication type J
Title Institutional traps and vulnerability to changes in climate and flood
regimes in Thailand
Author/s Lebel, L Manuta, JB Garden, P
Vol 11
Issue 1
Start page 45
End page 58
Publication year 2011
Times cited 0
Abstract Vulnerabilities to floods in Thailand are changing as a result of many
factors. Formal and informal institutions help shape exposure,
sensitivity and capacities to respond of individuals, social groups and
social-ecological systems. In this paper we draw on several case
studies of flood events and flood-affected communities to first assess
how current practices reflect various laws, procedures, programs and
policies for managing floods and disasters and then explore the
implications for dealing with additional challenges posed by climate
change. Our analysis identifies several institutional traps which need
to be overcome if vulnerability is to be reduced, namely capture of
agendas by technical elites, single-level or centralized concentration
of capacities, organizational fragmentation and overemphasis on
reactive crisis management. Possible responses are to expand public
participation in managing risks, build adaptive capacities at multiple
levels and link them, integrate flood disaster management and climate
change adaptation into development planning, prioritize risk reduction
for socially vulnerable groups and strengthen links between knowledge
and practice. Responses like these could help reduce vulnerabilities
under current climate and flood regimes, while also improving
capacities to handle the future which every way that unfolds.
UT WOS:000287596900004
SN 1436-3798
doi 10.1007/s10113-010-0118-4

Publication type J
Title Effect of water management on dry seeded and puddled transplanted rice.
Part 1: Crop performance
Author/s Sudhir-Yadav Gill, G Humphreys, E Kukal, SS Walia, US
Vol 120
Issue 1
Start page 112
End page 122
Publication year 2011
Times cited 0
Abstract An alarming rate of ground water depletion and increasing labour
scarcity are major threats to future rice production in north west
India. Management strategies that reduce the irrigation amount and
labour requirement while maintaining or increasing yield are urgently
needed. Dry seeded rice (DSR) has been proposed as one means of
achieving these objectives, but little is known about optimal water
management for DSR. Therefore a field study was conducted on a clay
loam soil in Punjab, India, during 2008 and 2009, to investigate the
effects of irrigation management on the performance of puddled
transplanted rice (PTR) and dry seeded rice. Irrigation scheduling
treatments were based on soil water tension (SWT) ranging from
ponding/saturation (daily irrigation) to alternate wetting and drying
(AWD) with irrigation thresholds of 20,40 and 70 kPa at 18-20 cm soil
depth. Rainfall was above average and well distributed in 2008 (822
mm), and average and less well distributed in 2009 (663 mm).
With daily irrigation, crop duration of PTR and DSR was the same.
Shifting from daily irrigation to AWD delayed crop maturity by 8-17 d,
and DSR was more affected than PTR, and more so in the drier year. Crop
performance in terms of tiller density, leaf area index and growth rate
was better in DSR than PTR with daily and 20 kPa irrigation scheduling.
However, crop performance was poorer in DSR than FTR at higher (40 and
70 kPa) irrigation thresholds, more so in the drier year when DSR
showed signs of severe iron deficiency which was not overcome with iron
sprays. Yield components were similar in both establishment methods
when irrigation was scheduled daily or at 20 kPa, but panicle density
and the number of filled grains per panicle were significantly lower at
40 and 70 kPa in DSR than PTR.
Each year, yield of DSR and PTR were similar when irrigation was
scheduled daily or at 20 kPa. Yields of both PTR and DSR declined under
higher water deficit stress (40 and 70 kPa irrigation thresholds), but
more so in DSR, and more so in the drier year. There was a very large
and significant decline in irrigation water input with irrigation at 20
kPa compared to daily irrigation in both establishment methods, but
only a very small decline in irrigation amount when the threshold was
increased from 20 to 40 and 70 kPa. Irrigation water use in DSR-AWD
treatments was significantly lower than in respective PTR treatments
(e.g. by 33-53% when irrigation was scheduled at 20 kPa).
The results suggest the feasibility of reducing irrigation amount while
maintaining yield by replacing PTR with DSR with AWD, provided that
soil tension is kept lower than 20 kPa at 20 cm depth, but that this
threshold needs to be tested over a wider range of seasonal and site
conditions and varieties. (C) 2010 Elsevier B.V. All rights reserved.
UT WOS:000289026500013
SN 0378-4290
doi 10.1016/j.fcr.2010.09.002

Publication type J
Title Effect of water management on dry seeded and puddled transplanted rice
Part 2: Water balance and water productivity
Author/s Sudhir-Yadav Humphreys, E Kukal, SS Gill, G Rangarajan, R
Vol 120
Issue 1
Start page 123
End page 132
Publication year 2011
Times cited 0
Abstract Labour and water scarcity in north west India are driving researchers
and farmers to find alternative management strategies that will
increase water productivity and reduce labour requirement while
maintaining or increasing land productivity. A field experiment was
done in Punjab. India, in 2008 and 2009 to compare water balance
components and water productivity of dry seeded rice (DSR) and puddled
transplanted rice (PTR). There were four irrigation schedules based on
soil water tension (SWT) ranging from saturation (daily irrigation) to
alternate wetting drying (AWD) with irrigation thresholds of 20, 40 and
70 kPa at 18-20 cm soil depth. There were large and significant
declines in irrigation water input with AWD compared to daily
irrigation in both establishment methods. The irrigation water savings
were mainly due to reduced deep drainage, seepage and runoff, and to
reduced ET in DSR. Within each irrigation treatment, deep drainage was
much higher in DSR than in PTR, and more so in the second year (i.e.
after 2 years without puddling). The irrigation input to daily
irrigated DSR was similar to or higher than to daily irrigated PTR.
However, within each AWD treatment, the irrigation input to DSR was
less than to PTR, due to reduced seepage and runoff, mainly because all
PTR treatments were continuously flooded for 2 weeks after
transplanting. There was 30-50% irrigation water saving in DSR-20 kPa
compared with PTR-20 kPa due to reduced seepage and runoff, which more
than compensated for the increased deep drainage in DSR. Yields of PTR
and DSR with daily irrigation and a 20 kPa irrigation threshold were
similar each year. Thus irrigation and input water productivities (WPI
and WPI+R) were highest with the 20 kPa irrigation threshold, and WPI
of DSR-20 kPa was 30-50% higher than of PTR-20 kPa. There was a
consistent trend for declining ET with decreasing frequency of
irrigation, but there was no effect of establishment method on ET apart
from higher ET in DSR than PTR with daily irrigation. Water
productivity with respect to ET (WPET) was highest with a 20 kPa
irrigation threshold, with similar values for DSR and PTR. An
irrigation threshold of 20 kPa was the optimum in terms of maximising
grain yield, WPI and WPI+R for both PTR and DSR. Dry seeded rice with
the 20 kPa threshold outperformed PTR-20 kPa in terms of WPI through
maintaining yield while reducing irrigation input by 30-50%. (C) 2010
Elsevier B.V. All rights reserved.
UT WOS:000289026500014
SN 0378-4290
doi 10.1016/j.fcr.2010.09.003

Publication type J
Title Phylogeny of Philippine slender skinks (Scincidae: Brachymeles) reveals
underestimated species diversity, complex biogeographical
relationships, and cryptic patterns of lineage diversification
Author/s Siler, CD Diesmos, AC Alcala, AC Brown, RM
Vol 59
Issue 1
Start page 53
End page 65
Publication year 2011
Times cited 0
Abstract The spectacular, virtually endemic radiation of Philippine
semi-fossorial skinks of the genus Brachymeles represent one of the few
radiations of scincid lizards to possess both fully limbed and limbless
species. And yet, nothing is known of the phylogenetic relationships of
this exceptional group. Morphologically similar body plans have made it
difficult to assess species-level diversity, and the genus has long
been recognized as one of the more modest radiations of southeast Asian
lizards. However, recent large-scale survey efforts have resulted in
the discovery of numerous new species, and taxonomic studies indicate
that the diversity within the genus Brachymeles is grossly
underestimated. In this study we provide the first robust estimate of
phylogenetic relationships within the genus Brachymeles using a
multi-locus dataset and nearly complete taxonomic sampling. We provide
statistical tests of monophyly for all polytypic species and two
widespread limb-reduced species and our results indicate wholesale
deviations from past summaries and taxonomic evaluations of the genus.
With few exceptions, we are able to reject the monophyly of all
polytypic and widespread species, thereby validating the need for
large-scale taxonomic revisions. Our results reveal that the limbless,
monotypic, genus Davewakeum is nested within Brachymeles. Mapping of
body form on our preferred phylogenetic tree suggests that
limb-reduction and digit loss has occurred on multiple occasions in the
history of the genus. A Bayesian reconstruction of ancestral areas
indicates strong statistical support for a minimum of five major
dispersal events that have given rise to a major component of the
observed species diversity on separate Pleistocene aggregate island
platforms of the archipelago. (C) 2011 Elsevier Inc. All rights
UT WOS:000289021000005
SN 1055-7903
doi 10.1016/j.ympev.2010.12.019

Publication type J
Title Assessing the Impact of Misclassification Error on an Epidemiological
Association between Two Helminthic Infections
Author/s Tarafder, MR Carabin, H McGarvey, ST Joseph, L Balolong, E Olveda, R
Vol 5
Issue 3
Publication year 2011
Times cited 0
Abstract Background: Polyparasitism can lead to severe disability in endemic
populations. Yet, the association between soil-transmitted helminth
(STH) and the cumulative incidence of Schistosoma japonicum infection
has not been described. The aim of this work was to quantify the effect
of misclassification error, which occurs when less than 100% accurate
tests are used, in STH and S. japonicum infection status on the
estimation of this association.
Methodology/Principal Findings: Longitudinal data from 2276
participants in 50 villages in Samar province, Philippines treated at
baseline for S. japonicum infection and followed for one year, served
as the basis for this analysis. Participants provided 1-3 stool samples
at baseline and 12 months later (2004-2005) to detect infections with
STH and S. japonicum using the Kato-Katz technique. Variation from
day-to-day in the excretion of eggs in feces introduces individual
variations in the sensitivity and specificity of the Kato-Katz to
detect infection. Bayesian logit models were used to take this
variation into account and to investigate the impact of
misclassification error on the association between these infections.
Uniform priors for sensitivity and specificity of the diagnostic test
to detect the three STH and S. japonicum were used. All results were
adjusted for age, sex, occupation, and village-level clustering.
Without correction for misclassification error, the odds ratios (ORs)
between hookworm, Ascaris lumbricoides, and Trichuris trichiura, and S.
japonicum infections were 1.28 (95% Bayesian credible intervals: 0.93,
1.76), 0.91 (95% BCI: 0.66, 1.26), and 1.11 (95% BCI: 0.80, 1.55),
respectively, and 2.13 (95% BCI: 1.16, 4.08), 0.74 (95% BCI: 0.43,
1.25), and 1.32 (95% BCI: 0.80, 2.27), respectively, after correction
for misclassification error for both exposure and outcome.
Conclusions/Significance: The misclassification bias increased with
decreasing test accuracy. Hookworm infection was found to be associated
with increased 12-month cumulative incidence of S. japonicum infection
after correction for misclassification error. Such important
associations might be missed in analyses which do not adjust for
misclassification errors.
UT WOS:000288940800026
SN 1935-2727
doi 10.1371/journal.pntd.0000995

Publication type J
Title A multicentre surveillance study on the characteristics, bacterial
aetiologies and in vitro antibiotic susceptibilities in patients with
acute exacerbations of chronic bronchitis
Author/s Hui, DS Ip, M Ling, T Chang, SC Liao, CH Yoo, CG Kim, DK Yoon, HI Udompanich, V Mogmeud, S Muttalif, R Salleh, AM Roa, C Mendoza, M Fajardo-Ang, C Soepandi, P Isbaniah, F Burhan, E Sudarmono, P Mangunnegoro, H Liu, HH
Journal source RESPIROLOGY
Vol 16
Issue 3
Start page 532
End page 539
Publication year 2011
Times cited 0
Abstract Background and objective: Antimicrobial resistance is a global problem
and the prevalence is high in many Asian countries.
Methods: A prospective observational study of the prevalence of
bacterial pathogens and their antimicrobial susceptibilities in
patients with acute exacerbations of chronic bronchitis (AECB) was
conducted in Indonesia, Philippines, Korea, Thailand, Malaysia, Taiwan
and Hong Kong from August 2006 to April 2008. The diagnosis of AECB was
based on increased cough and worsening of two of following: dyspnoea,
increased sputum volume or purulence. Patients who had taken
antibiotics within 72 h of presentation were excluded. All bacterial
strains were submitted to a central laboratory for re-identification
and antimicrobial susceptibility testing to 16 antimicrobial agents
according to Clinical and Laboratory Standards Institute.
Results: Four hundred and seven isolates were identified among 447
patients of AECB. The most frequent organisms isolated were Klebsiella
pneumoniae and associated species (n = 91 + 17), Haemophilus influenzae
(n = 71), Pseudomonas aeruginosa (n = 63), Streptococcus pneumoniae (n
= 32), Acinetobacter baumannii (n = 22) and Moraxella catarrhalis (n =
21). According to Clinical and Laboratory Standards Institute
susceptibility breakpoints, 85.7% and >90% of these pathogens were
susceptible to levofloxacin and cefepime respectively. Other options
with overall lower susceptibilities include imipenem, ceftazidime,
ceftriaxone and amoxicillin/clavulanate.
Conclusions: Gram-negative bacteria including Klebsiella spp., P.
aeruginosa and Acinetobacter spp. constitute a large proportion of
pathogens identified in patients with AECB in some Asian countries.
Surveillance on the local prevalence and antibiotic resistance of these
organisms is important in guiding appropriate choice of antimicrobials
in the management of AECB.
UT WOS:000288959600021
SN 1323-7799
doi 10.1111/j.1440-1843.2011.01943.x

Publication type J
Title Phase II, Open-Label Study of Brivanib as First-Line Therapy in
Patients with Advanced Hepatocellular Carcinoma
Author/s Park, JW Finn, RS Kim, JS Karwal, M Li, RK Ismail, F Thomas, M Harris, R Baudelet, C Walters, I Raoul, JL
Vol 17
Issue 7
Start page 1973
End page 1983
Publication year 2011
Times cited 0
Abstract Purpose: Brivanib, a selective dual inhibitor of fibroblast growth
factor and VEGF signaling, has demonstrated encouraging antitumor
activity in preclinical and phase I studies. We performed a phase II
open-label study of brivanib as first-line therapy in patients with
unresectable, locally advanced, or metastatic hepatocellular carcinoma.
Experimental Design: Brivanib was administered orally at a dose of 800
mg once daily. The primary objective was 6-month progression-free
survival, progression-free survival rate; secondary objectives were
tumor response rate, time to response, duration of response, median
progression-free survival, median overall survival, disease control
rate (complete response, partial response, or stable disease >= 42
days), and safety and tolerability.
Results: Between March 2007 and May 2009, 55 patients were treated and
were evaluable for response. Patients were assessed using modified
World Health Organization (mWHO) criteria. According to mWHO criteria
and as assessed by Independent Response Review Committee, the six-month
progression-free survival rate (95% CI) was 18.2% (9.1%-30.9%). Median
progression-free survival (95% CI) was 2.7 months (1.4-3.0). One
patient achieved a complete response and three achieved a partial
response. Twenty-two had stable disease. Median overall survival (95%
CI) was 10 (6.8-15.2) months. Brivanib was generally well tolerated;
the most common adverse events included fatigue, hypertension, and
Conclusion: Brivanib as first-line therapy demonstrates promising
antitumor activity and a manageable safety profile in patients with
advanced, unresectable HCC. Clin Cancer Res; 17(7); 1973-83. (C)2011
UT WOS:000289054100035
SN 1078-0432
doi 10.1158/1078-0432.CCR-10-2011

Publication type J
Title Oral L-Ornithine-L-Aspartate Improves Health-Related Quality of Life in
Cirrhotic Patients with Hepatic Encephalopathy An Open-Label,
Prospective, Multicentre Observational Study
Author/s Ong, JP Oehler, G Kruger-Jansen, C Lambert-Baumann, J Younossi, ZM
Vol 31
Issue 4
Start page 213
End page 220
Publication year 2011
Times cited 0
Abstract Background and Objective: Hepatic encephalopathy (HE) is a serious
complication of cirrhosis. Clinical trials have consistently shown that
L-ornithine-L-aspartate significantly improves HE symptoms.
Health-related quality of life (HR-QOL) is impaired in HE patients and
represents an important outcome measure for therapeutic intervention.
The present study aimed to assess the impact of L-ornithine-L-aspartate
on HR-QOL and safety in patients with HE in a clinical practice
Methods: This was an open-label, prospective, multicentre observational
study in clinical practice (general practitioners in Germany) that
included 191 cirrhotic patients with HE. Patients were administered
three sachets daily of L-ornithine-L-aspartate 6 g (Hepa-Merz (R), Merz
Pharmaceuticals GmbH, Frankfurt/Main, Germany) dissolved in water taken
during or after meals. L-ornithine-L-aspartate was administered over a
period of 8 weeks. The main outcome variable was the mean change in
HR-QOL over the observation period as assessed by the patients using
the German-validated version of the Chronic Liver Disease Questionnaire
(CLDQ-D). Further assessments included mean changes in the severity of
cirrhosis/HE-related symptoms, changes in disease severity (measured on
the modified Clinical Global Impression-Severity [CGI-S] scale), and
changes in disease status (measured on the modified CGI-Improvement
[CGI-I] scale).
Results: Treatment with L-ornithine-L-aspartate for 8 weeks markedly
improved all HR-QOL domains, in particular fatigue (67.5% improvement),
resulting in a mean +/- SD CLDQ-D sum score improvement from 3.53 +/-
1.03 at baseline to 5.04 +/- 0.93 at the end of treatment. Symptom
severity also improved, with particular benefits seen in fatigue, sleep
quality and concentration deficits. Patient self-assessment correlated
well with the physicians’ clinical evaluation. Physicians rated 70.0%
of the patients very much or much improved at the end of treatment.
Very good or good tolerability was observed in 97.8% of patients. No
drug-related adverse events were reported.
Conclusion: Treatment of HE with oral L-ornithine-L-aspartate in
cirrhotic patients markedly improved HR-QOL and was well tolerated by
97.8% of patients.
UT WOS:000289122500001
SN 1173-2563

Publication type J
Title Pushing on a string: How policy might encourage private doctors to
compete with the public sector on the basis of quality
Author/s Quimbo, S Peabody, JW Javier, X Shimkhada, R Solon, O
Vol 110
Issue 2
Start page 101
End page 103
Publication year 2011
Times cited 0
Abstract Results from the Philippine Quality Improvement Demonstration Study
show that a policy that expands insurance coverage improves quality of
care, as measured by clinical performance vignettes, among public
physicians, and induces a spillover effect that improves quality among
private physicians. (C) 2010 Elsevier B.V. All rights reserved.
UT WOS:000288309200009
SN 0165-1765
doi 10.1016/j.econlet.2010.10.021

Publication type J
Title Detection and genetic analysis of aquabirnaviruses in subclinically
infected aquarium fish
Author/s Shin, SP Gomez, DK Kim, JH Choresca, CH Han, JE Jun, JW Park, SC
Vol 23
Issue 2
Start page 325
End page 329
Publication year 2011
Times cited 0
Abstract Aquabirnaviruses (ABVs) cause serious diseases in a variety of fish
species used worldwide in aquaculture and have been isolated from a
variety of healthy fish and shellfish species. The type species of ABV
is Infectious pancreatic necrosis virus (IPNV), which is the causative
agent of a highly contagious disease in juvenile salmonid fish. Marine
birnaviruses (MABVs) have been isolated from various marine fish and
shellfish. In Korea, ABV infection has been identified in several fish
and shellfish. The current study presents sequence data from nested
polymerase chain reaction products of 3 ABV strains obtained from
different species of asymptomatic aquarium fish collected from a
private commercial aquarium in Korea. Phylogenetic analysis of these
strains, based on the partial nucleotide sequence of the VP2/NS
junction, placed them within the genogroup VII (95-99% bootstrap
confidence), which also contains MABV. The subclinically infected fish
may be a source of MABV infection for other susceptible fish species
inside the aquarium and potentially represent a serious challenge for
the management of MABV infections. Additionally, the presence of MABV
in these subclinically infected aquarium fish imported from other
countries indicates that there is a need for the establishment of
appropriate quarantine
UT WOS:000288838300021
SN 1040-6387

Publication type J
Title Blood transfer devices for malaria rapid diagnostic tests: evaluation
of accuracy, safety and ease of use
Author/s Hopkins, H Oyibo, W Luchavez, J Mationg, ML Asiimwe, C Albertini, A Gonzalez, IJ Gatton, ML Bell, D
Journal source MALARIA JOURNAL
Vol 10
Publication year 2011
Times cited 0
Abstract Background: Malaria rapid diagnostic tests (RDTs) are increasingly used
by remote health personnel with minimal training in laboratory
techniques. RDTs must, therefore, be as simple, safe and reliable as
possible. Transfer of blood from the patient to the RDT is critical to
safety and accuracy, and poses a significant challenge to many users.
Blood transfer devices were evaluated for accuracy and precision of
volume transferred, safety and ease of use, to identify the most
appropriate devices for use with RDTs in routine clinical care.
Methods: Five devices, a loop, straw-pipette, calibrated pipette, glass
capillary tube, and a new inverted cup device, were evaluated in
Nigeria, the Philippines and Uganda. The 227 participating health
workers used each device to transfer blood from a simulated
finger-prick site to filter paper. For each transfer, the number of
attempts required to collect and deposit blood and any spilling of
blood during transfer were recorded. Perceptions of ease of use and
safety of each device were recorded for each participant. Blood volume
transferred was calculated from the area of blood spots deposited on
filter paper.
Results: The overall mean volumes transferred by devices differed
significantly from the target volume of 5 microliters (p < 0.001). The
inverted cup (4.6 microliters) most closely approximated the target
volume. The glass capillary was excluded from volume analysis as the
estimation method used is not compatible with this device. The
calibrated pipette accounted for the largest proportion of blood
exposures (23/225, 10%); exposures ranged from 2% to 6% for the other
four devices. The inverted cup was considered easiest to use in blood
collection (206/ 226, 91%); the straw-pipette and calibrated pipette
were rated lowest (143/225 [ 64%] and 135/225 [60%] respectively).
Overall, the inverted cup was the most preferred device (72%, 163/227),
followed by the loop (61%, 138/227).
Conclusions: The performance of blood transfer devices varied in this
evaluation of accuracy, blood safety, ease of use, and user preference.
The inverted cup design achieved the highest overall performance, while
the loop also performed well. These findings have relevance for any
point-of-care diagnostics that require blood sampling.
UT WOS:000288812600004
SN 1475-2875
doi 10.1186/1475-2875-10-30

Publication type J
Title On the deficiency index of even order symmetric differential
expressions with essential spectrum
Author/s Roque, MP Schultze, B
Vol 284
Issue 5-6
Start page 790
End page 796
Publication year 2011
Times cited 0
Abstract It shall be shown that for every n, k epsilon N with n <= k < 2n, there
exist real symmetric differential expressions M of order 2n with
nonempty essential spectrum such that d(M) = k. (C) 2011 WILEY-VCH
Verlag GmbH & Co. KGaA, Weinheim
UT WOS:000289006100017
SN 0025-584X
doi 10.1002/mana.200810141

Publication type J
Unfettered Finance in the 1990s and 2000s
Author/s Park, CY
Journal source PACIFIC AFFAIRS
Vol 84
Issue 1
Start page 109
End page 110
Publication year 2011
Times cited 0
UT WOS:000288362900006
SN 0030-851X

Publication type J
Title THINGS FALL AWAY: Philippine Historical Experience and the Makings of
Author/s Gealogo, FA
Journal source PACIFIC AFFAIRS
Vol 84
Issue 1
Start page 197
End page 199
Publication year 2011
Times cited 0
UT WOS:000288362900056
SN 0030-851X

Publication type J
Title The January 2009 anomalous precipitation associated with the “Tail-end
of the Cold Front” weather system in Northern and Eastern Mindanao
(Philippines): Natural hazards, impacts and risk reductions
Author/s Faustino-Eslava, DV Yumul, GP Servando, NT Dimalanta, CB
Vol 76
Issue 1-2
Start page 85
End page 94
Publication year 2011
Times cited 0
Abstract In the first half of January 2009, the southern Philippine island of
Mindanao was overwhelmed by numerous natural disasters caused by the
passage of the tail-end of the cold front. This otherwise ordinary
weather condition was accompanied by unusually heavy precipitation
sustained over a period of several days. This triggered numerous
landslides and caused many drainage systems to swell, flooding huge
tracts of low lying areas that have not experienced similar events in
the recent past. Many communities were caught unprepared for the
calamity. The amount and extent of damage reflect both the magnitude of
the natural disaster itself and the community’s nominal level of
disaster-preparedness. In view of the increasing atmospheric moisture
levels and the likelihood that global warming will affect the weather
patterns, there is a possibility that similar weather disturbances can
become more frequent. Therefore, there is an urgent need for disaster
risk management programs to be developed or enhanced at the local
community level especially in areas most vulnerable to weather-related
natural hazards, in light of changing global climatic patterns. (C)
2010 Elsevier B.V. All rights reserved.
UT WOS:000288934400008
SN 0921-8181
doi 10.1016/j.gloplacha.2010.12.009

Publication type J
Title Exclusive breastfeeding of low birth weight infants for the first six
months: infant morbidity and maternal and infant anthropometry
Author/s Agrasada, GV Ewald, U Kylberg, E Gustafsson, J
Vol 20
Issue 1
Start page 62
End page 68
Publication year 2011
Times cited 0
Abstract Background: to report anthropometry and morbidity among term low birth
weight infants and anthropometry of their first time mothers during the
first six months in relation to breastfeeding practice. Methods: we
examined data from a randomized controlled trial in Manila, the
Philippines. Of the 204 mothers randomized, 68 mothers received eight
postpartum breastfeeding counseling sessions, the rest did not.
Maternal and infant anthropometric data at birth, 2, 4 and 6 months
were taken. During seven follow-up hospital visits, an independent
interviewer recorded feeding data. Results: the 24 infants exclusively
breastfed from birth to six months did not have diarrhea compared to
134 partially breastfed (mean 2.3 days) and 21 non-breastfed infants
(mean 2.5 days). Partially breastfed and non-breastfed infants compared
to exclusively breastfed infants had more frequent, as well as more
severe episodes of respiratory infections. At six months, neither
overall gain in infant weight, length and head circumferences nor mean
maternal weight and body mass index differed significantly between the
feeding groups. Conclusions: exclusive breastfeeding for 6 months can
be recommended in term low birth weight infants, who were protected
from diarrhea, had fewer respiratory infections, required no
hospitalization and had catch up growth. Exclusively breastfeeding
mothers did not differ from mothers who breastfed partially or those
who did not breastfeed with regard to weight changes at six months.
UT WOS:000289186200011
SN 0964-7058

Publication type J
Title Drought-induced site-specific DNA methylation and its association with
drought tolerance in rice (Oryza sativa L.)
Author/s Wang, WS Pan, YJ Zhao, XQ Dwivedi, D Zhu, LH Ali, J Fu, BY Li, ZK
Vol 62
Issue 6
Start page 1951
End page 1960
Publication year 2011
Times cited 0
Abstract An indica pyramiding line, DK151, and its recurrent parent, IR64, were
evaluated under drought stress and non-stress conditions for three
consecutive seasons. DK151 showed significantly improved tolerance to
drought. The DNA methylation changes in DK151 and IR64 under drought
stress and subsequent recovery were assessed using
methylation-sensitive amplified polymorphism analysis. Our results
indicate that drought-induced genome-wide DNA methylation changes
accounted for similar to 12.1% of the total site-specific methylation
differences in the rice genome. This drought-induced DNA methylation
pattern showed three interesting properties. The most important one was
its genotypic specificity reflected by large differences in the
detected DNA methylation/demethylation sites between DK151 and IR64,
which result from introgressed genomic fragments in DK151. Second, most
drought-induced methylation/demethylation sites were of two major types
distinguished by their reversibility, including 70% of the sites at
which drought-induced epigenetic changes were reversed to their
original status after recovery, and 29% of sites at which the
drought-induced DNA demethylation/methylation changes remain even after
recovery. Third, the drought-induced DNA methylation alteration showed
a significant level of developmental and tissue specificity. Together,
these properties are expected to have contributed greatly to rice
response and adaptation to drought stress. Thus, induced epigenetic
changes in rice genome can be considered as a very important regulatory
mechanism for rice plants to adapt to drought and possibly other
environmental stresses.
UT WOS:000288553000018
SN 0022-0957
doi 10.1093/jxb/erq391

Publication type J
Title Absorption of Lithium in Montmorillonite: A Density Functional Theory
(DFT) Study
Author/s Wungu, TDK Aspera, SM David, MY Dipojono, HK Nakanishi, H Kasai, H
Vol 11
Issue 4
Start page 2793
End page 2801
Publication year 2011
Times cited 0
Abstract The absorption of lithium in montmorillonite [LiSi8(Al3Mg)O-20(OH)(4)]
was investigated using Density Functional Theory (DFT). The final
position of lithium after absorption was found to be in good agreement
with an experimental observation where lithium atom migrated from the
interlayer into the vacant octahedral site of montmorillonite. The
lithium absorbed on montmorillonite was held together by a very strong
attraction between ions and exhibited an insulating behavior as
depicted from the density of states curve. Due to the presence of
lithium in the octahedral site of montmorillonite, the OH group
reoriented itself perpendicular to the ab plane and an electron of
lithium was transferred in order to compensate the existing net charge
of montmorillonite caused by isomorphous substitutions. Relative small
charge transfer was observed between lithium and montmorillonite.
UT WOS:000289176100005
SN 1533-4880
doi 10.1166/jnn.2011.3913

Publication type J
Title Genome-wide temporal-spatial gene expression profiling of drought
responsiveness in rice
Author/s Wang, D Pan, YJ Zhao, XQ Zhu, LH Fu, BY Li, ZK
Journal source BMC GENOMICS
Vol 12
Publication year 2011
Times cited 0
Abstract Background: Rice is highly sensitive to drought, and the effect of
drought may vary with the different genotypes and development stages.
Genome-wide gene expression profiling was used as the initial point to
dissect molecular genetic mechanism of this complex trait and provide
valuable information for the improvement of drought tolerance in rice.
Affymetrix rice genome array containing 48,564 japonica and 1,260
indica sequences was used to analyze the gene expression pattern of
rice exposed to drought stress. The transcriptome from leaf, root, and
young panicle at three developmental stages was comparatively analyzed
combined with bioinformatics exploring drought stress related
Results: There were 5,284 genes detected to be differentially expressed
under drought stress. Most of these genes were tissue-or stage-specific
regulated by drought. The tissue-specific down-regulated genes showed
distinct function categories as photosynthesis-related genes prevalent
in leaf, and the genes involved in cell membrane biogenesis and cell
wall modification over-presented in root and young panicle. In a
drought environment, several genes, such as GA2ox, SAP15, and Chitinase
III, were regulated in a reciprocal way in two tissues at the same
development stage. A total of 261 transcription factor genes were
detected to be differentially regulated by drought stress. Most of them
were also regulated in a tissue-or stage-specific manner. A cis-element
containing special CGCG box was identified to over-present in the
upstream of 55 common induced genes, and it may be very important for
rice plants responding to drought environment.
Conclusions: Genome-wide gene expression profiling revealed that most
of the drought differentially expressed genes (DEGs) were under
temporal and spatial regulation, suggesting a crosstalk between various
development cues and environmental stimuli. The identification of the
differentially regulated DEGs, including TF genes and unique candidate
cis-element for drought responsiveness, is a very useful resource for
the functional dissection of the molecular mechanism in rice responding
to environment stress.
UT WOS:000289066700001
SN 1471-2164
doi 10.1186/1471-2164-12-149

Publication type J
Title Novel therapeutic vaccine Granulysin and new DNA vaccine against
Author/s Okada, M Kita, Y Nakajima, T Kanamaru, N Hashimoto, S Nagasawa, T Kaneda, Y Yoshida, S Nishida, Y Nakatani, H Takao, K Kishigami, C Nishimatsu, S Sekine, Y Inoue, Y Matsumoto, M McMurray, DN Dela Cruz, EC Tan, EV Abalos, RM Burgos, JA Saunderson, P Sakatani, M
CT 7th World Congress on Vaccines, Immunisation and Immunotherapy (WCVII)
CY MAY 26-28, 2010
Journal source HUMAN VACCINES
Vol 7
Start page 60
End page 67
Publication year 2011
Times cited 0
Abstract Purpose: Multi-drug resistant (MDR) Mycobacterium tuberculosis (M. TB)
is a big problem in the world. We have developed novel TB therapeutic
Results and Methods: DNA vaccine expressing mycobacterial heat shock
protein 65 and IL-12 was delivered by the hemagglutinating virus of
Japan (HVJ)-envelope. M.TB, MDR-TB or extremenly drug resistant
(XDR-TB) was injected i.v. into DBA/1 mice, and treated with the
vaccine three times. This HVJ-E/Hsp65DNA+IL-12DNA vaccine provided
strong therapeutic efficacy against MDR-TB and XDR-TB (prolongation of
survival time and the decrease in the number of TB) in mice.
Therapeutic effect of this vaccine on TB infection was also
demonstrated in chronic TB infection murine model using aerosol
infection intratracheally. On the other hand, granulysin protein
produced from CTL has lethal activity against TB. Granulysin protein
vaccine also exerted strong therapeutic effect. Furthermore, we
extended our studies to monkey model, which is currently the best
animal model of human TB. Hsp65DNA+IL-12 DNA vaccine exerted strong
therapeutic efficacy (100% survival and augmentation of immune
responses) in the TB-infected monkeys. In contrast, the survival of the
saline control group was 60% at 16 week post-challenge.
HVJ-Envelope/HSP65 DNA+IL-12 DNA vaccine increased the body weight of
TB-infected monkeys, improved the erythrocyte sedimentation rate and
augmentated the immune responses (proliferation of PBL and IL-2
production). The enhancement of IL-2 production from monkeys treated
with this vaccine was correlated with the therapeutic efficacy of the
Conclusion: These data indicate that novel vaccines might be useful
against TB including XDR-TB and MDR-TB for human therapeutic clinical
UT WOS:000288984200010
SN 1554-8600
doi 10.4161/hv.7.0.14563

Publication type J
Title Development of therapeutic and prophylactic vaccine against
tuberculosis using monkey and transgenic mice models
Author/s Kita, Y Okada, M Nakajima, T Kanamaru, N Hashimoto, S Nagasawa, T Kaneda, Y Yoshida, S Nishida, Y Nakatani, H Takao, K Kishigami, C Nishimatsu, S Sekine, Y Takamori, Y McMurray, DN De la Cruz, EC Tan, EV Abalos, RM Burgos, JA Saunderson, P Sakatani, M
CT 7th World Congress on Vaccines, Immunisation and Immunotherapy (WCVII)
CY MAY 26-28, 2010
Journal source HUMAN VACCINES
Vol 7
Start page 108
End page 114
Publication year 2011
Times cited 0
Abstract Purpose: BCG is not efficacious against M. tuberculosis (TB) in adult.
Therefore, novel TB vaccines were established by using three kinds of
animal models (cynomolgus monkey model which is the best animal model
of human TB, IL-2R knock out SCID mice as a human immune model and
granulysin transgenic mouse).
Methods and Results: DNA vaccine expressing TB Hsp65 and IL-12 was
delivered by the hemagglutinating virus of Japan (HVJ)-envelope. The
BCG prime followed by Hsp65 + IL-12/HVJ vaccine boost showed a
synergistic effect in the TB-infected cynomolgus monkey (100%
survival). In contrast, 33% of monkeys were alive in BCG alone group.
Furthermore, the prolongation of survival period of the monkey was
observed by the combination of BCG and DNA vaccine even when the boost
was performed after long-term period (4 month) from prime. This
combination also improved the erythrocyte sedimentation rate (ESR),
increased the body weight and augmented the proliferation of PBL and
IL-12 production at higher levels than BCG alone or saline.
Furthermore, this vaccine exerted therapeutic efficacy in IL-2R knock
out SCID-PBL/hu mice, which were transplanted with human T cells.
Granulysin is an important defensive molecule expressed by human T
cells and NK cells and has a cytolytic activity against microbes
including Mycobacterium tuberculosis (TB) and tumors. Expression of 15
kD (15 K) granulysin protein and mRNA in CD8 positive T cells in the
patients infected with drug sensitive (TB) or multidrug resistant M.
tuberculosis (MDR-TB) were lower than that in the healthy volunteers,
suggesting that granulysin treatment might improve the tuberculous
disease in human. Therefore, we established two kinds of granulysin
transgenic mice (15 K granulysin transgenic mice and 9 K granulysin
transgenic mice). It was demonstrated that 15 K granulysin transgenic
mice as well as 9 K granulysin transgenic mice exerted in vivo anti-TB
effect, including the decrease of the number of TB and augmentation of
the CTL activity. These are the first findings which demonstrate in
vivo effects of 15 K granulysin and 9 K granulysin against TB
infection. Moreover, DNA vaccine expressing 15 K granulysin showed a
therapeutic activity against TB in mice.
Conclusion: These data indicate that monkey, IL-2R gene-knock out
SCID-PBL/hu and granulysin transgenic mice models provide useful tools
for the development of novel vaccines (HVJ-Envelope/Hsp65 DNA + IL-12
DNA vaccine and granulysin vaccine) against TB.
UT WOS:000288984200016
SN 1554-8600
doi 10.4161/hv.7.0.14571

Publication type J
Title Asian Financial Cooperation in the 1990s: The Politics of Membership
Author/s Hamanaka, S
Vol 11
Issue 1
Start page 75
End page 103
Publication year 2011
Times cited 0
Abstract A commonplace view holds that the trend toward Asian financial
regionalism is a relatively new phenomenon, developing in response to
the 1997-1998 Asian financial crisis in particular. In this article I
challenge this view by analyzing financial regionalist projects before
the crisis. Asian countries, especially Japan, sought to establish an
Asia-only financial cooperation framework throughout the 1990s. The
policy stance of the United States, in contrast, was to participate in
Asian forums and/or by itself propose and establish regional groupings
that included the United States. This competition between Japan and the
United States is a key factor in understanding the rise and fall of
various regionalist projects and also has theoretical implications for
membership politics in regional financial cooperation frameworks.
UT WOS:000288106400003
SN 1598-2408

Publication type J
Title Relationship between Symptoms and Gene Expression Induced by the
Infection of Three Strains of Rice dwarf virus
Author/s Satoh, K Shimizu, T Kondoh, H Hiraguri, A Sasaya, T Choi, IR Omura, T Kikuchi, S
Journal source PLOS ONE
Vol 6
Issue 3
Publication year 2011
Times cited 0
Abstract Background: Rice dwarf virus (RDV) is the causal agent of rice dwarf
disease, which often results in severe yield losses of rice in East
Asian countries. The disease symptoms are stunted growth, chlorotic
specks on leaves, and delayed and incomplete panicle exsertion. Three
RDV strains, O, D84, and S, were reported. RDV-S causes the most severe
symptoms, whereas RDV-O causes the mildest. Twenty amino acid
substitutions were found in 10 of 12 virus proteins among three RDV
Methodology/Principal Findings: We analyzed the gene expression of rice
in response to infection with the three RDV strains using a 60-mer
oligonucleotide microarray to examine the relationship between symptom
severity and gene responses. The number of differentially expressed
genes (DEGs) upon the infection of RDV-O, -D84, and -S was 1985, 3782,
and 6726, respectively, showing a correlation between the number of
DEGs and symptom severity. Many DEGs were related to defense, stress
response, and development and morphogenesis processes. For defense and
stress response processes, gene silencing-related genes were activated
by RDV infection and the degree of activation was similar among plants
infected with the three RDV strains. Genes for hormone-regulated
defense systems were also activated by RDV infection, and the degree of
activation seemed to be correlated with the concentration of RDV in
plants. Some development and morphogenesis processes were suppressed by
RDV infection, but the degree of suppression was not correlated well
with the RDV concentration.
Conclusions/Significance: Gene responses to RDV infection were
regulated differently depending on the gene groups regulated and the
strains infecting. It seems that symptom severity is associated with
the degree of gene response in defense-related and development- and
morphogenesis-related processes. The titer levels of RDV in plants and
the amino acid substitutions in RDV proteins could be involved in
regulating such gene responses.
UT WOS:000288809100031
SN 1932-6203
doi 10.1371/journal.pone.0018094

Publication type J
Author/s Quimbo, SA Peabody, JW Shimkhada, R Florentino, J Solon, O
Vol 20
Issue 5
Start page 620
End page 630
Publication year 2011
Times cited 0
Abstract In this paper, we present evidence on the health effects of a health
insurance intervention targeted to poor children using data from a
randomized policy experiment known as the Quality Improvement
Demonstration Study. Among study participants, using a
difference-in-difference regression model, we estimated a 9-12 and 4-9
percentage point reduction in the likelihood of wasting and having an
infection, respectively, as measured by a common biomarker C-reactive
Protein. Interestingly, these benefits were not apparent at the time of
discharge; the beneficial health effects were manifest several weeks
after release from the hospital. Copyright (C) 2010 John Wiley & Sons,
UT WOS:000288815800008
SN 1057-9230
doi 10.1002/hec.1621

Publication type J
Title Ego Integrity of Older People with Physical Disability and Therapeutic
Author/s de Guzman, AB Shim, HE Sia, CKM Siazon, WHS Sibal, MJAP Siglos, JBLC Simeon, FMC
Vol 37
Issue 4
Start page 265
End page 291
Publication year 2011
Times cited 0
Abstract Ego integrity, the last developmental task in Erikson’s psychological
theory, develops naturally among older people. However, the presence of
loss-like physical disability-can considerably affect the quality of
life, interactions, and well being of older adults. Hence, older people
with physical disabilities need more assistance in accomplishing tasks
of ego integrity. This study aimed to utilize traditional Filipino art
to capture the essence of the lived experiences of a select group of
older people with physical disabilities in relation to their ego
integrity. Four Filipino elderly with physical disabilities were
purposely selected for this study. Picture prompting and doodling
sessions were held as pretest and posttest to ascertain the
effectiveness of puni-making in facilitating ego integrity of
participants. A series of interviews were pursued to elicit experiences
and feelings of participants regarding their disability and old age.
From the analysis of the triangulated set of data, two findings
emerged. First, four activators of ego integrity, namely: work, family,
belief in self and belief in God, were identified as essentials in the
formation of the participants’ ego-integrity. Second, shifts related to
the activators were identified indicating ego integrity’s source,
meaning and connection elements have become more grounded, certain and
integrated. The influence of puni-making in understanding the ego
integrity of older people with disabilities was found to be a sound and
novel recreational therapy. It can stimulate a select group of Filipino
elderly for openness to share their subjective and yet illuminating
life experiences.
UT WOS:000288666200001
SN 0360-1277
doi 10.1080/03601270903534945

Publication type J
Title Cancer survival differences between European countries and an urban
population from the Philippines
Author/s Redaniel, MT Laudico, A Mirasol-Lumague, MR Gondos, A Brenner, H
Vol 21
Issue 2
Start page 221
End page 228
Publication year 2011
Times cited 0
Abstract Background: The EUROCARE study has disclosed large variations of
survival across Europe, with the magnitude varying, depending on cancer
site. Comparisons of these rates with those from the developing
countries are rare, but important in evaluating international cancer
care discrepancies. This study aimed to provide up-to-date estimates of
cancer survival in a Philippine urban population, and to compare these
with those observed in the European countries. Methods: Using the
results from the EUROCARE-4 study, the survival estimates of the
European patients who were diagnosed in 1995-99 and followed till
December 2003 were abstracted. From randomly selected samples drawn
from the Manila and Rizal Cancer Registries, 5-year survival was
estimated for nine common cancers. Age-adjusted survival estimates were
then compared between the Philippine population and Europeans. Results:
In comparison to the European mean, survival estimates for the
Philippine residents were lower for most cancers, with differences
ranging from 2 to 40% units. Differences with European country-specific
estimates were large for cancers of the breast and cervix, where early
detection is possible, and for leukaemia, where treatment regimens are
costly, highlighting the importance of health care. Smaller
discrepancies were observed for stomach, liver and lung cancers, with
the 5-year relative survival being similar to the Philippines and to
many European countries. A survival advantage was seen though for the
Philippine residents for ovarian cancer. Conclusion: Apart from efforts
to prevent cancers, improvements in cancer control and making early
diagnosis and treatment more accessible remain major challenges, both
in the Philippines and in the European nations.
UT WOS:000288806600018
SN 1101-1262
doi 10.1093/eurpub/ckq031

Publication type J
Title Women’s Empowerment in Pakistan-Definitions and Enabling and
Disenabling Factors: A Secondary Data Analysis
Author/s Bustamante-Gavino, MI Rattani, S Khan, K
Vol 22
Issue 2
Start page 174
End page 181
Publication year 2011
Times cited 0
Abstract Purpose: The purpose of the study was to explore Pakistani women’s
definition of women’s empowerment, including its enabling and
disenabling factors. Through understanding empowerment, interventions
may be developed for women to be empowered. Design: Transcriptions of
35 interviews from a previous study were reanalyzed through secondary
data analysis. Findings/Results: The themes of economic stability,
social acceptability, educational achievement, and family harmony
emerged for the concept of definition of empowerment. Themes for
enabling factors were strength of personality and openness of mind.
Disenabling factors had sociocultural influences, religious
misinterpretations, and dominant ideology as themes.
Discussion/Conclusions: Pakistani women hold on to their customs,
traditions, and religion tenaciously. The views of empowerment leading
to the themes were expressed as true for their lives.
UT WOS:000289171000010
SN 1043-6596
doi 10.1177/1043659610395762

Publication type J
Title Dynamic modelling and control of fully rated converter wind turbines
Author/s Caliao, ND
Vol 36
Issue 8
Start page 2287
End page 2297
Publication year 2011
Times cited 0
Abstract Today, many countries are integrating large amount of wind energy into
the grid and many more are expected to follow. The expected increase of
wind energy integration is therefore a concern particularly to
transmission grid operators. Based on the past experience, some of the
relevant concerns when connecting significant amount of wind energy
into the existing grid are: fault ride through requirement to keep wind
turbines on the grid during faults and wind turbines have to provide
ancillary services like voltage and frequency control with particular
regard to island operation.
While there are still a number of wind turbines based on fixed speed
induction generators (FSIG) currently running, majority of wind
turbines that are planned to be erected are of variable speed
configurations. The reason for this is that FSIG are not capable of
addressing the concern mentioned above. Thus, existing researches in
wind turbines are now widely directed into variable speed
configurations. This is because apart from optimum energy capture and
reduction of mechanical stress, preference of these types is also due
to the fact that it can support the network such as its reactive power
and frequency regulation. Variable wind turbines are doubly fed
induction generator wind turbines and full converters wind turbines
which are based on synchronous or induction generators.
This paper describes the steady state and dynamic models and control
strategies of wind turbine generators. The dynamic models are presented
in the dq frame of reference. Different control strategies in the
generator side converter and in the grid side converter for fault ride
through requirement and active power/frequency and reactive/voltage
control are presented for variable speed wind turbines. (C) 2011
Elsevier Ltd. All rights reserved.
UT WOS:000289128100027
SN 0960-1481
doi 10.1016/j.renene.2010.12.025

Publication type J
Title Monitoring Cry1Ab susceptibility in Asian corn borer (Lepidoptera:
Crambidae) on Bt corn in the Philippines
Author/s Alcantara, E Estrada, A Alpuerto, V Head, G
Journal source CROP PROTECTION
Vol 30
Issue 5
Start page 554
End page 559
Publication year 2011
Times cited 0
Abstract Between 2002 and 2004, collections of egg masses of Asian corn borer
(ACB), Ostrinia furnacalis (Guenee) were made from corn-planting sites
on the major Philippine islands of Luzon (Laguna, Pangasinan, Camarines
Sur and Isabela provinces) and Mindanao (Bukidnon and South Cotabato
provinces). The resulting neonates were bioassayed for susceptibility
to Bacillus thuringiensis (Bt) Cry1Ab protein. The median lethal
concentrations (LC(50)s) for the different collections ranged from 0.42
to 2.37 ng/cm(2). The bioassay results suggest that Philippine corn
borer populations were highly susceptible to Cry1Ab protein prior to
the widespread deployment of Bt corn. The upper limit of the estimated
LC99 (104 ng/cm(2)) from the pooled bioassay data was selected as a
candidate diagnostic concentration and subsequently tested on eleven
ACB populations. Results of the validation assays showed that the
mortality response of all the tested ACB populations was higher than
the expected mortality (99%). Therefore, the concentration of 104
ng/cm(2) was used to monitor susceptibility in ACB populations in the
Philippines. Monitoring of field populations during 2009 in areas where
Bt corn had been grown for 3 years found some enhanced survival of
neonates at the diagnostic concentration but progeny of the
diagnostic-concentration survivors did not survive on Bt corn,
indicating that ACB populations in the Philippines remain susceptible
to Cry1Ab-containing Bt corn hybrids. (C) 2010 Elsevier Ltd. All rights
UT WOS:000289332500006
SN 0261-2194
doi 10.1016/j.cropro.2010.12.019

Publication type J
Title Does susceptibility to heat stress confound screening for drought
tolerance in rice?
Author/s Jagadish, KSV Cairns, JE Kumar, A Somayanda, IM Craufurd, PQ
Vol 38
Issue 4
Start page 261
End page 269
Publication year 2011
Times cited 0
Abstract Drought affected rice areas are predicted to double by the end of this
century, demanding greater tolerance in widely adapted mega-varieties.
Progress on incorporating better drought tolerance has been slow due to
lack of appropriate phenotyping protocols. Furthermore, existing
protocols do not consider the effect of drought and heat interactions,
especially during the critical flowering stage, which could lead to
false conclusion about drought tolerance. Screening germplasm and
mapping-populations to identify quantitative trait loci (QTL)/candidate
genes for drought tolerance is usually conducted in hot dry seasons
where water supply can be controlled. Hence, results from dry season
drought screening in the field could be confounded by heat stress,
either directly on heat sensitive processes such as pollination or
indirectly by raising tissue temperature through reducing
transpirational cooling under water deficit conditions.
Drought-tolerant entries or drought-responsive candidate genes/QTL
identified from germplasm highly susceptible to heat stress during
anthesis/flowering have to be interpreted with caution. During drought
screening, germplasm tolerant to water stress but highly susceptible to
heat stress has to be excluded during dry and hot season screening.
Responses to drought and heat stress in rice are compared and results
from field and controlled environment experiments studying drought and
heat tolerance and their interaction are discussed.
UT WOS:000289260700001
SN 1445-4408
doi 10.1071/FP10224

Publication type J
Title Numerical correction of optical vortex using a wrapped phase map
analysis algorithm
Author/s Maallo, AMS Almoro, PF
Journal source OPTICS LETTERS
Vol 36
Issue 7
Start page 1251
End page 1253
Publication year 2011
Times cited 0
Abstract We demonstrate experimentally a technique for the numerical correction
of an optical vortex with a unitary topological charge. A developed
algorithm based on the axial behavior of a reconstructed wavefront is
used in the detection of the optical vortex. Optimizations of the
number of axial phase maps and the window size used in the algorithm
yield the precise coordinates of the vortex eye. The obtained
coordinates and vortex handedness are used in designing a proper
filter, facilitating numerical correction of the vortex phase map. The
developed algorithm can be applied to absolute phase and phase
difference maps obtained through any reconstruction method. (C) 2011
Optical Society of America
UT WOS:000289251000077
SN 0146-9592

Publication type J
Title Effect of multiple infestations from insect pests and other stresses on
irrigated rice in the Philippines: I. Damage functions
Author/s Litsinger, JA Bandong, JP Canapi, BL
Vol 57
Issue 2
Start page 93
End page 116
Publication year 2011
Times cited 1
Abstract Artificial infestation methods were employed to generate damage
function graphs for guilds of three rice insect pests. In the
vegetative stage, infestation of whorl maggot (Hydrellia philippina
Ferino) and defoliators (a mixed population of Naranga aenescens Moore
and Rivula atimeta [Swinhoe]) was applied as a combined or single pest
attack. Infestation of yellow stemborer (Scirpophaga incertulas
[Walker]) and leaffolder (Cnaphalocrocis medinalis [Guenee]) each were
infested in one or two crop growth stages. Combinations of three
stresses (four N application rates, solar radiation from the wet or dry
season, and/or the presence or absence of weeds) were applied to each
guild to develop more holistic economic injury levels (EILs). Slopes on
the linear portion of damage curves of each pest guild became steeper
with each additional stress applied, whether from multiple insect pest
attack, low N, low solar radiation, or weeds. EILs can be developed by
pest managers from the graphs of the damage functions for the variables
quantified in this study.
UT WOS:000290044900001
SN 0967-0874
doi 10.1080/09670874.2010.530355

Publication type J
Title Effect of multiple infestations from insect pests and other stresses to
irrigated rice in the Philippines: II. Damage and yield loss
Author/s Litsinger, JA Bandong, JP Canapi, BL
Vol 57
Issue 2
Start page 117
End page 131
Publication year 2011
Times cited 0
Abstract Single and multiple species infestations of common insect pests were
compared in terms of yield loss involving crop stresses that included
weeds, sheath blight (Rhizoctonia solani Kunh.), drought, and
deficiencies of N and solar radiation in addition to insect pest
infestations. Losses from the various combinations of stresses were
found to be additive, antagonistic, or synergistic. Most combinations
of insect pests produced additive losses, with the balance being
antagonistic, so implying that compensation occurred. Combinations of
insect damage with other biotic and abiotic stresses produced mostly
synergistic crop losses, which were significantly greater than additive
ones. Among insect pests, additive losses resulted from yellow
stemborer (Scirpophaga incertulas [Walker]) attacking two rice growth
stages while the same was true for leaffolder (Cnaphalocrocis medinalis
[Guenee]). Only the combination of whorl maggot (Hydrellia philippina
Ferino) and defoliators (a mixture of Naranga aenescens Moore and
Rivula atimeta [Swinhoe]) produced synergistic losses. Knowing the mode
of yield loss from combinations of different plant stresses will aid
the farmer in making decisions regarding which ones should be corrected
and which the crop can tolerate.
UT WOS:000290044900002
SN 0967-0874
doi 10.1080/09670874.2010.537792

Publication type J
Title Cleaning up the ‘Bigmessidae’: Molecular phylogeny of scleractinian
corals from Faviidae, Merulinidae, Pectiniidae and Trachyphylliidae
Author/s Huang, DW Licuanan, WY Baird, AH Fukami, H
Vol 11
Publication year 2011
Times cited 0
Abstract Background: Molecular phylogenetic studies on scleractinian corals have
shown that most taxa are not reflective of their evolutionary
histories. Based principally on gross morphology, traditional taxonomy
suffers from the lack of well-defined and homologous characters that
can sufficiently describe scleractinian diversity. One of the most
challenging clades recovered by recent analyses is ‘Bigmessidae’, an
informal grouping that comprises four conventional coral families,
Faviidae, Merulinidae, Pectiniidae and Trachyphylliidae, interspersed
among one another with no apparent systematic pattern. There is an
urgent need for taxonomic revisions in this clade, but it is vital to
first establish phylogenetic relationships within the group. In this
study, we reconstruct the evolutionary history of ‘Bigmessidae’ based
on five DNA sequence markers gathered from 76 of the 132 currently
recognized species collected from five reef regions in the central
Indo-Pacific and the Atlantic.
Results: We present a robust molecular phylogeny of ‘Bigmessidae’ based
on the combined five-gene data, achieving a higher degree of resolution
compared to previous analyses. Two Pacific species presumed to be in
‘Bigmessidae’ are more closely related to outgroup clades, suggesting
that other unsampled taxa have unforeseen affinities. As expected,
nested within ‘Bigmessidae’ are four conventional families as listed
above, and relationships among them generally corroborate previous
molecular analyses. Our more resolved phylogeny supports a close
association of Hydnophora (Merulinidae) with Favites + Montastraea
(Faviidae), rather than with the rest of Merulinidae, i.e., Merulina
and Scapophyllia. Montastraea annularis, the only Atlantic
‘Bigmessidae’ is sister to Cyphastrea, a grouping that can be
reconciled by their septothecal walls, a microstructural feature of the
skeleton determined by recent morphological work. Characters at the
subcorallite scale appear to be appropriate synapomorphies for other
subclades, which cannot be explained using macromorphology. Indeed,
wide geographic sampling here has revealed more instances of possible
cryptic taxa confused by evolutionary convergence of gross coral
Conclusions: Numerous examples of cryptic taxa determined in this study
support the assertion that diversity estimates of scleractinian corals
are erroneous. Fortunately, the recovery of most ‘Bigmessidae’ genera
with only minor degrees of paraphyly offers some hope for impending
taxonomic amendments. Subclades are well defined and supported by
subcorallite morphological features, providing a robust framework for
further systematic work.
UT WOS:000289410500002
SN 1471-2148
doi 10.1186/1471-2148-11-37

Publication type J
Title Determining the basis of nonhost resistance in rice to cereal rusts
Author/s Ayliffe, M Jin, Y Kang, ZS Persson, M Steffenson, B Wang, SP Leung, H
Journal source EUPHYTICA
Vol 179
Issue 1
Start page 33
End page 40
Publication year 2011
Times cited 0
Abstract Cereal rusts are a constant disease threat that limits the production
of almost all agricultural cereals. Rice is atypical in that it is an
intensively grown agricultural cereal that is immune to rust pathogens.
This immunity is manifested by nonhost resistance (NHR), the mechanisms
of which are poorly understood. As part of the Borlaug Global Rust
Initiative (BGRI), studies are being undertaken to dissect the
molecular mechanisms that provide rust immunity in rice and determine
if they can be transferred to wheat via transgenesis. Microscopic
analyses showed that cereal rusts are capable of entering the rice leaf
via formation of an appressorium over a stomate and subsequent
infection of underlying mesophyll cells. However, there is considerable
variation in the extent of colonization at each infection site. Our
research effort has focused on screening for increased growth of cereal
rust using natural and induced variants of rice. Two collections of
rice mutants, T-DNA insertional mutants and
chemical/irradiation-induced mutants, and diverse germplasm accessions
are being screened for compromised NHR to cereal rusts. Preliminary
screening with stripe rust identified several potential mutants that
allow increased fungal growth. The confirmation of these lines will
serve as the foundation for the isolation of gene(s) responsible for
this compromised resistance. Details of the strategies being undertaken
and progress to date are provided.
UT WOS:000289305300004
SN 0014-2336
doi 10.1007/s10681-010-0280-2

Publication type J
Title Tolerance of longer-term partial stagnant flooding is independent of
the SUB1 locus in rice
Author/s Singh, S Mackill, DJ Ismail, AM
Vol 121
Issue 3
Start page 311
End page 323
Publication year 2011
Times cited 0
Abstract Longer-term partial stagnant flooding, particularly when it occurs
following transient complete submergence causes severe damage to modern
rice varieties. Progress was made in developing varieties tolerant of
complete submergence through transfer of the Submergence-1 (SUB1) gene
into popular varieties. However, SUB1 may not be effective under
partial stagnant flooding (SF), as the new varieties may not elongate
and continue growth when fully or partially submerged because of the
SUB I-mediated suppression of elongation. We tested a set of rice
genotypes, including a pair of near-isogenic lines (NILs), Swarna and
Swarna-Sub1, under either SF or SF following complete submergence of
12d. Swarna-Sub1 had higher survival and yield than Swarna following
12d of submergence, but survival and grain yield of all lines decreased
substantially when SF of 15-30 cm followed complete submergence, with
the sensitive lines experiencing greater reductions in growth and
yield. This suggests the importance of combining SUB1 with tolerance of
SF in areas where both stresses are expected during the season. Swarna
and Swarna-Sub1 are more sensitive to long-term partial SF than
11249830 and IR42 because of their short stature, and Swarna-Sub1
showed slightly higher reduction in tillering than did Swarna when
subjected to deeper SF alone, possibly because of further inhibition of
elongation by SUB1 if induced in submerged tissue. The results suggest
that tolerance of these genotypes to SF depends less on SUB1
introgression and more so on the genetic background of the recipient
genotype, with better performance of the genotypes that are inherently
taller, such as IR42 and IR49830. The SUB1 donor landrace FR13A and its
derivative breeding line IR49830 had better survival and relatively
less reduction in grain yield under SF following complete submergence
and under longer-term partial SF, indicating that these genotypes may
have genes other than SUB1 for submergence and SF tolerance. For better
adaptation to prolonged SF. SUB1 should be introgressed into genotypes
that tolerate partial SF through better tillering ability and taller
shoots, because SUB1 may not be effective in shorter genotypes, as it
promotes survival of submerged plants by hindering shoot elongation to
conserve energy reserves. Varieties combining tolerance of prolonged SF
with SUB1 will have broader adaptation in flood-prone areas and greater
impacts on yield stability. (C) 2011 Elsevier B.V. All rights reserved.
UT WOS:000289399800002
SN 0378-4290
doi 10.1016/j.fcr.2010.12.021

Publication type J
Title Effects of long-term use of sodic water irrigation, amendments and crop
residues on soil properties and crop yields in rice-wheat cropping
system in a calcareous soil
Author/s Choudhary, OP Ghuman, BS Bijay-Singh Thuy, N Buresh, RJ
Vol 121
Issue 3
Start page 363
End page 372
Publication year 2011
Times cited 0
Abstract One of the options to ameliorate the deleterious effects of sodic water
irrigation is to apply gypsum to soil. We examined whether the
application of organic manures or crop residue can reduce the need for
gypsum in calcareous soils. A long-term field experiment with annual
rice-wheat cropping rotation was conducted for 15 years (1991-2006) on
a non-saline calcareous sandy loam soil (Typic Ustochrept) in
northwestern, India. The irrigation water treatments included good
quality canal water (CW) and sodic water (SW) with residual sodium
carbonate (RSC) of 10 mmol(c) L-1 from 1991 to 1999 and of 12.5 mmol(c)
L-1 from 2000 onwards. Gypsum was applied at 0, 12.5, 25, and 50% of
the gypsum requirement (GR), to neutralize RSC of the SW. Three organic
material treatments consisted of application of farmyard manure (FYM)
at 20 Mg ha(-1), Sesbania green manure (GM) at 20 Mg ha(-1), and wheat
straw (WS) at 6 Mg ha(-1). The organic materials were applied every
year to the rice crop. Continuous irrigation with sodic water for 15
years without gypsum or organic materials resulted in a gradual
increase in soil pH and exchangeable sodium percentage (ESP),
deterioration of soil physical properties, and decrease in yields of
both rice and wheat. The cumulative yield loss in SW irrigated plots
without gypsum and organic materials remained <1.5 Mg ha(-1) for up to
eight years in the case of rice and up to nine years in the case of
wheat. Thereafter, marked increase in pH and ESP resulted in further
depression in yields of rice by 1.6 Mg ha(-1) year(-1) and wheat by 1.2
Mg ha(-1) year(-1). Application of gypsum improved physical and
chemical properties of the soil. The beneficial effects on crop yields
were visible up to 12.5% GR in rice and up to 50% GR in wheat in most
of the years. All the organic materials proved effective in mobilizing
Ca2+ from inherent and precipitated CaCO3 resulting in decline in soil
pH and ESP, increase in infiltration rate, and a increase in the yields
of rice and wheat crops. Although the application of organic materials
resulted in comparable reductions in pH and ESP, the increase in yield
with SW was higher for both crops with FYM. Pooled over the last six
years (2000-2006), application of FYM resulted in 38 and 26% increase
in rice and wheat yields, respectively, over SW treatment;
corresponding increases in 50% GR treatment (recommended level) was 18
and 19%. During these years, application of GM and WS increased wheat
yields by 20%; for rice, GM resulted in 22% increase compared to 17% in
WS amended SW irrigated plots. Combined application of gypsum and
organic materials did not increase the yields further particularly in
the case of FYM and GM treated plots. This long-term study proves that
organic materials alone can be used to solubilize Ca from inherent and
precipitated CaCO3 in calcareous soils for achieving sustainable yields
in sodic water irrigated rice-wheat grown in annual rotation. The
results can help reduce the dependency on gypsum in sodic water
irrigated calcareous soils. (C) 2011 Elsevier B.V. All rights reserved.
UT WOS:000289399800007
SN 0378-4290
doi 10.1016/j.fcr.2011.01.004

Publication type J
Title Effects and fate of biochar from rice residues in rice-based systems
Author/s Haefele, SM Konboon, Y Wongboon, W Amarante, S Maarifat, AA Pfeiffer, EM Knoblauch, C
Vol 121
Issue 3
Start page 430
End page 440
Publication year 2011
Times cited 0
Abstract Although crop residues constitute an enormous resource, actual residue
management practices in rice-based systems have various negative side
effects and contribute to global warming. The concept of a combined
bioenergy/biochar system could tackle these problems in a new way. Rice
residues would be used for energy production, thereby reducing field
burning and the use of fossil fuels, and the biochar by-product could
help to improve soils, avoid methane emissions, and sequester carbon in
soils. To examine some of these promises, we conducted field
experiments from 2005 to 2008 in three different rice production
systems. Objectives were to study the effect of biochar from rice husks
on soil characteristics, assess the stability of carbonized rice
residues in these different systems, and evaluate the agronomic effect
of biochar applications. The results showed that application of
untreated and carbonized rice husks (RH and CRH) increased total
organic carbon, total soil N. the C/N ratio, and available P and K. Not
significant or small effects were observed for soil reaction,
exchangeable Ca, Mg, Na, and the CEC. On a fertile soil, the high C/N
ratio of CRH seemed to have limited N availability, thereby slightly
reducing grain yields in the first three seasons after application. On
a poor soil, where the crop also suffered from water stress, soil
chemical and physical improvements increased yields by 16-35%. Together
with a parallel study including methane and CO2 emission measurements
at one site, the results strongly suggest that CRH is very stable in
various rice soils and systems, possibly for thousands of years.
However, the study also showed that CRH was very mobile in some soils.
Especially in poor sandy soil, about half of the applied carbon seemed
to have moved below 0.30 m in the soil profile within 4 years after
application. We concluded that biochar from rice residues can be
beneficial in rice-based systems but that actual effects on soil
fertility, grain yield, and soil organic carbon will depend on
site-specific conditions. Long-term studies on biochar in field trials
seem essential to better understand biochar effects and to investigate
its behavior in soils. (C) 2011 Elsevier B.V. All rights reserved.
UT WOS:000289399800015
SN 0378-4290
doi 10.1016/j.fcr.2011.01.014

Publication type J
Title Influence of the soil physical environment on rice (Oryza sativa L.)
response to drought stress and its implications for drought research
Author/s Cairns, JE Impa, SM O’Toole, JC Jagadish, SVK Price, AH
Vol 121
Issue 3
Start page 303
End page 310
Publication year 2011
Times cited 0
Abstract Plant performance under drought stress is not solely defined by an
inadequate water supply but by an interaction among many factors,
including climatic, edaphic, and biological factors. An important
interacting factor affecting root growth, and therefore the ability of
a plant to access and take up water, is the soil physical environment.
Soil penetration resistance can restrict, or even halt, root system
growth. For rice, a soil penetration resistance of 1.4 MPa is
sufficient to inhibit root system expansion. This review describes the
effects of the soil physical environment on root growth and its
interaction with drought stress. A large variation in soil penetration
resistance exists among rainfed rice-growing areas of South and
Southeast Asia and within experimental stations used for
managed-drought field phenotyping. This variability may influence
genotypic performance across experimental sites/countries and the
response of crop genotypes to drought stress. A case study is presented
in which differences in the soil physical environment may partially
elucidate differences in experimental results between two field studies
conducted at different locations. These results highlight the need for
increased knowledge of environmental interactions to allow the outputs
of genomics to increase drought tolerance at the field level. (C) 2011
Elsevier B.V. All rights reserved.
UT WOS:000289399800001
SN 0378-4290
doi 10.1016/j.fcr.2011.01.012

Publication type J
Title Barang king banga: A Visayan language reading of the Calatagan pot
inscription (CPI)
Author/s Guillermo, RG Paluga, MJD
Vol 42
Issue 1
Start page 121
End page 159
Publication year 2011
Times cited 0
Abstract The Calatagan pot, with an inscription around its rim, is one of the
very few existing archeological evidences of ancient writing in the
Philippines. It was discovered in Calatagan, Batangas and bought by the
Philippine National Museum in 1961. Having since eluded decipherment,
the present paper proposes a strategy which combines traditional
palaeographic techniques and cryptographic methods. By means of this
procedure, a tentative decipherment of the inscription is proposed
here. The preliminary results show that the inscription is some kind of
ancient spell or charm written in a central Philippine language with a
Javanese admixture.
UT WOS:000286958300006
SN 0022-4634
doi 10.1017/S0022463410000561

Publication type J
Title Detection and subtype identification of Blastocystis isolates from
wastewater samples in the Philippines
Author/s Banaticla, JEG Rivera, WL
Vol 9
Issue 1
Start page 128
End page 137
Publication year 2011
Times cited 0
Abstract To provide further evidence of waterborne transmission of Blastocystis,
a total of 31 wastewater treatment plants from geographically distinct
locations across the Philippines were sampled for influent and effluent
sewage samples. In vitro cultivation was the method of choice to
increase sensitivity of detection. Blastocystis cysts were detected in
15% (9/62) of the samples using in vitro culture. Moreover, influent
and effluent samples were 23% (7/31) and 7% (2/31) positive for the
parasite, respectively. The presence of viable cysts in treated samples
may be an indication of the inefficiency of the treatment process in
preventing Blastocystis from entering the environment. Polymerase chain
reaction and sequencing of the full-length small subunit ribosomal RNA
(SSU rRNA) genes of the nine wastewater isolates were performed. The
SSU rRNA gene sequences of the isolates showed very high similarity (98
to 99%) to homologous sequences of Blastocystis described previously.
The phylogenetic tree constructed showed that the wastewater isolates
clustered with each other with good bootstrap support and belonged to
two subtypes (ST) – ST1 and ST2. This is the first report of subtyping
Blastocystis isolates from wastewater samples and gives further
emphasis to the remarkable genetic diversity of the parasite.
UT WOS:000289387900012
SN 1477-8920
doi 10.2166/wh.2010.127

Publication type J
Author/s Del Vecchio, FB Franchini, E Del Vecchio, AHM Pieter, W
Journal source BIOLOGY OF SPORT
Vol 28
Issue 1
Start page 75
End page 78
Publication year 2011
Times cited 0
Abstract Objective: Although some scientific information on electronic body
protectors in taekwondo is available, no research has been done to
assess the impact of kicks in a competitive situation. The purpose of
this study, then, was to assess the energy absorbed by these protectors
from kicks performed in an actual taekwondo competition. Methods:
Subjects consisted of junior (14-17 years) and senior (>= 18 years)
male taekwondo-in, who participated in an open tournament. Data on the
energy imparted by valid kicks in Joules (1) were collected from a
public visual electronic monitor. Results: Energy was higher for the
seniors: 264.31 +/- 56.63 J versus 224.38 +/- 48.23 J for the juniors
(eta(2) = 0.121). The seniors scored lower in percent impact but the
effect was trivial: 123.46 +/- 24.77% versus 136.70 +/- 26.33% (eta(2)
= 0.087). Conclusions: The difference between senior and junior
taekwondo-in in absolute energy generated was small, while the
difference in relative energy impact was trivial in favour of the
junior taekwondo athletes.
UT WOS:000289182300012
SN 0860-021X

Publication type J
Title A World Health Organization Framework for Zoonoses in the Asia-Pacific
Author/s Kasai, T
Journal source ECOHEALTH
Vol 7
Start page S125
End page S125
Publication year 2011
Times cited 0
UT WOS:000287901500219
SN 1612-9202

Publication type J
Title Eco-Bio-Social Research for Dengue Prevention and Control in Asia – A
study in 6 Countries
Author/s Kittayapong, P Abeyewickreme, W Arunachalam, N Espino, F Tana, S Wai, KT Horstick, O Sommerfeld, J
Journal source ECOHEALTH
Vol 7
Start page S130
End page S130
Publication year 2011
Times cited 0
UT WOS:000287901500230
SN 1612-9202

Publication type J
Title Safety and immunogenicity of a tetravalent meningococcal serogroups A,
C, W-135 and Y conjugate vaccine in adolescents and adults
Author/s Bermal, N Huang, LM Dubey, AP Jain, H Bavdekar, A Lin, TY Bianco, V Baine, Y Miller, JM
Journal source HUMAN VACCINES
Vol 7
Issue 2
Start page 239
End page 247
Publication year 2011
Times cited 0
Abstract The highest incidence of invasive meningococcal disease is in young
children, with a second peak in adolescents/young adults. All five
major disease-causing serogroups (A, B, C, W-135 and Y) have been
described in Asia. Immunogenicity and safety of the investigational
meningococcal ACWY-tetanus toxoid conjugate vaccine (ACWY-TT,
GlaxoSmithKline Biologicals) was evaluated in healthy, meningococcal
conjugate vaccine-nave adolescents in the Philippines, India and
Taiwan. 1,025 adolescents were randomized (3:1) to receive one dose of
ACWY-TT or tetravalent ACWY polysaccharide vaccine (Mencevax (TM),
Men-PS). Serum bactericidal activity using rabbit complement (rSBA) was
measured. Local and systemic adverse reactions were recorded for 4
days. Safety data were pooled with results from a second, similarly
designed study in adults for evaluation of grade 3 systemic events. The
pre-specified immunogenicity criterion for non-inferiority to Men-PS
was met. One month post-vaccination, >= 85.4%-97.1% had a vaccine
response (post-titre >= 1:8 in initially seronegative and >= 4-fold
increase in seropositive), versus 78.0%-96.6% after Men-PS, against
each vaccine serogroup. Exploratory comparisons showed statistically
significantly higher post-vaccination rSBA geometric mean titres
against all serogroups following ACWY-TT versus Men-PS. Exploratory
analysis showed no statistically significant differences between groups
in grade 3 general symptoms; however, the statistical criterion for
non-inferiority between pooled treatment groups in terms of the ratio
of incidences of grade 3 general symptoms was not demonstrated. No SAEs
were related to vaccination. ACWY-TT was immunogenic in Asian
adolescents with a reactogenicity profile that was clinically
acceptable and similar to that of licensed Men-PS. The results of this
study indicate that ACWY-TT could be used as a third conjugate vaccine
in the protection of adolescents against meningococcal disease.
UT WOS:000288990900015
SN 1554-8600
doi 10.4161/hv.7.2.14068

Publication type J
Title Arthropod diversity and community composition on wild and cultivated
Author/s Chen, YH Bernal, CC
Vol 13
Issue 2
Start page 181
End page 189
Publication year 2011
Times cited 0
Abstract Most crop plants are grown far from their region of origin and have
been significantly altered by human selection. Given the importance of
biodiversity in ecosystem function, surprisingly little is known about
the effect of domestication on arthropod diversity and community
Arthropod diversity and species abundance were compared with three
genotypes of cultivated rice Oryza sativa L. and two genotypes of wild
rice O. rufipogon Griff. in southern Luzon, the Philippines.
Domestication had a small but positive effect on total arthropod
diversity. Arthropod species richness was highest on the cultivar IR64
and lowest on one of the O. rufipogon genotypes, although arthropod
community composition was similar across rice genotypes.
Total arthropod abundance and the relative abundance of guilds did not
differ between wild and cultivated rice. All common herbivores,
however, responded to rice domestication. Stem-boring moths and several
sap-sucking herbivores benefited from domestication, although
domestication reduced densities of the wolf spider Pardosa
pseudoannulata Boesenberg et Strand.
By contrast to previous assumptions, crop domestication may not always
decrease arthropod diversity. We did not detect any changes in
biodiversity or community composition suggesting that rice
domestication has altered the capacity of the arthropod community to
regulate herbivores.
UT WOS:000289468200009
SN 1461-9555
doi 10.1111/j.1461-9563.2010.00510.x

Publication type J
Title Financial Incentives And Measurement Improved Physicians’ Quality Of
Care In The Philippines
Author/s Peabody, J Shimkhada, R Quimbo, S Florentino, J Bacate, M McCulloch, CE Solon, O
Journal source HEALTH AFFAIRS
Vol 30
Issue 4
Start page 773
End page 781
Publication year 2011
Times cited 0
Abstract The merits of using financial incentives to improve clinical quality
have much appeal, yet few studies have rigorously assessed the
potential benefits. The uncertainty surrounding assessments of quality
can lead to poor policy decisions, possibly resulting in increased cost
with little or no quality improvement, or missed opportunities to
improve care. We conducted an experiment involving physicians in thirty
Philippine hospitals that overcomes many of the limitations of previous
studies. We measured clinical performance and then examined whether
modest bonuses equal to about 5 percent of a physician’s salary, as
well as system-level incentives that increased compensation to
hospitals and across groups of physicians, led to improvements in the
quality of care. We found that both the bonus and system-level
incentives improved scores in a quality measurement system used in our
study by ten percentage points. Our findings suggest that when careful
measurement is combined with the types of incentives we studied, there
may be a larger impact on quality than previously recognized.
UT WOS:000289233400031
SN 0278-2715
doi 10.1377/hlthaff.2009.0782

Publication type J
Title Gross and Fine Anatomy of the Respiratory Vasculature of the
Mudskipper, Periophthalmodon schlosseri (Gobiidae: Oxudercinae)
Author/s Gonzales, TT Katoh, M Ghaffar, MA Ishimatsu, A
Vol 272
Issue 5
Start page 629
End page 640
Publication year 2011
Times cited 0
Abstract To illustrate vascular modification accompanying transition from
aquatic to amphibious life in gobies, we investigated the respiratory
vasculatures of the gills and the bucco-opercular cavities in one of
the most terrestrially-adapted mudskippers, Periophthalmodon
schlosseri, using the corrosion casting technique. The vascular system
of Pn. schlosseri retains the typical fish configuration with a serial
connection of the gills and the systemic circuits, suggesting a lack of
separation of O-2-poor systemic venous blood and O-2-rich effluent
blood from the air-breathing surfaces. The gills appear to play a
limited role in gas exchange, as evidenced from the sparsely-spaced
short filaments and the modification of secondary lamellar vasculature
into five to eight parallel channels that are larger than red blood
cell size, unlike the extensive sinusoidal system seen in purely
water-breathing fishes. In contrast, the epithelia of the
bucco-opercular chamber, branchial arches, and leading edge of the
filaments are extensively laden with capillaries having a short (< 10
mu m) diffusion distance, which strongly demonstrate the principal
respiratory function of these surfaces. These capillaries form spiral
coils of three to five turns as they approach the epithelial surface.
The respiratory capillaries of the bucco-opercular chamber are supplied
by efferent blood from the gills and drained by the systemic venous
pathway. We also compared the degree of capillarization in the
bucco-opercular epithelia of Pn. schlosseri with that of the three
related intertidal-burrowing gobies (aquatic, non-air-breathing
Acanthogobius hasta; aquatic, facultative air-breathing Odontamblyopus
lacepedii; amphibious air-breathing Periophthalmus modestus) through
histological analysis. The comparison revealed a clear trend of wider
distribution of denser capillary networks in these epithelia with
increasing reliance on air breathing, consistent with the highest
aerial respiratory capacity of Pn. schlosseri among the four species.
J. Morphol. 272:629-640, 2011. (C) 2011Wiley-Liss, Inc.
UT WOS:000289435500011
SN 0362-2525
doi 10.1002/jmor.10944

Publication type J
Title Relative effects of ammonia and nitrite on the germination and early
growth of aerobic rice
Author/s Haden, VR Xiang, J Peng, SB Bouman, BAM Visperas, R Ketterings, QM Hobbs, P Duxbury, JM
Vol 174
Issue 2
Start page 292
End page 300
Publication year 2011
Times cited 0
Abstract Recent studies have documented adverse affects of urea on the
establishment and growth of aerobic rice when applied at seeding. The
following experiments were conducted to examine the relative importance
of ammonia and nitrite (NO2-) toxicities as mechanisms contributing to
poor germination and early growth of aerobic rice. Soil was collected
from an experiment in the Philippines where aerobic rice was grown
continuously for 7 years. Subsamples of the soil were: (1) pretreated
with sulfuric acid (0.5 M H2SO4 added at 75 mL kg(-1)), (2) oven-heated
at 120 degrees C for 12 h, or (3) left untreated. In a greenhouse study
N was applied to the untreated, acidified, and oven-heated soils as
either urea or ammonium sulfate (0.0 or 0.3 g N kg(-1)). Plant height,
root length, total biomass, and number of seminal roots were evaluated
after 10 d. Microdiffusion incubations were used to assess the effects
of soil pretreatment, N source, and N rate (0, 0.5, 1.0, 1.5 g N
kg(-1)) on ammonia (NH3) volatilization and germination. Nitrite
incubations were conducted to establish a critical level for NO2-
toxicity and measure the extractable NO2- and germination trends as
affected by soil pretreatment, N source, and N rate. On untreated soil,
urea reduced early growth and germination while ammonium sulfate caused
no adverse effects. Progressively higher rates of urea increased NH3
volatilization and inhibited germination, while oven-heating and
acidification minimized the adverse effects. All treatment combinations
(soil pretreatment, N source, N rate) had extractable NO2- levels below
the critical level of 0.2 g N kg(-1), suggesting that ammonia and not
NO2- toxicity was the principal cause of inhibition. Since the risk of
NH3 toxicity is highest just following urea hydrolysis, strategies to
optimize the timing and placement of urea should be considered.
UT WOS:000289443100013
SN 1436-8730
doi 10.1002/jpln.201000222

Publication type J
Title The role of beta-blockers in the management of hypertension: An Asian
Author/s Tomlinson, B Dalal, JJ Huang, J Low, LP Park, CG Rahman, AR Reyes, EB Soenarta, AA Heagerty, A Follath, F
Vol 27
Issue 5
Start page 1021
End page 1033
Publication year 2011
Times cited 0
Abstract Following publication of the National Institute of Clinical Excellence
(NICE) Guidelines in 2006, the use of beta beta-blockers as first-line
therapy in hypertension has been somewhat controversial. However, a
recent reappraisal of the European Society of Hypertension guidelines
highlights that these agents exhibit similar Start page lowering efficacy to
other classes of agents, prompting a re-examination of the utility of
these agents in various patient populations. The authors felt that it
is important to address this controversy and provide an Asian
perspective on the place of beta beta-blockers in current clinical
practice and the benefits of beta beta-blockade in selected patient
populations. In addition to their use as a potential first-line therapy
in uncomplicated hypertension, beta beta-blockers have a particular
role in patients with hypertension and comorbidities such as heart
failure or coronary artery disease, including those who had a
myocardial infarction. One advantage which beta beta-blockers offer is
the additional protective effects in patients with prior cardiovascular
events. Some of the disadvantages attributed to beta beta-blockers
appear more related to the older drugs in this class and further
appraisal of the efficacy and safety profile of newer beta
beta-blockers will lend support to the current guideline
recommendations in Asian countries and encourage increased appropriate
use of beta beta-blockade in current clinical practice within Asia.
UT WOS:000289528000015
SN 0300-7995
doi 10.1185/03007995.2011.562884

Publication type J
Title Spread of methicillin-resistant Staphylococcus aureus between the
community and the hospitals in Asian countries: an ANSORP study
Author/s Song, JH Hsueh, PR Chung, DR Ko, KS Kang, CI Peck, KR Yeom, JS Kim, SW Chang, HH Kim, YS Jung, S ISon, JS So, TMK Lalitha, MK Yang, YH Huang, SG Wang, H Lu, QA Carlos, CC Perera, JA Chiu, CH Liu, JW Chongthaleong, A Thamlikitkul, V Van, PH
Vol 66
Issue 5
Start page 1061
End page 1069
Publication year 2011
Times cited 1
Abstract Objectives: Methicillin-resistant Staphylococcus aureus (MRSA) is
highly prevalent in hospitals in many Asian countries. Recent emergence
of community-associated (CA) MRSA worldwide has added another serious
concern to the epidemiology of S. aureus infections. To understand the
changing epidemiology of S. aureus infections in Asian countries, we
performed a prospective, multinational surveillance study with
molecular typing analysis.
Methods: We evaluated the prevalence of methicillin resistance in S.
aureus isolates in CA and healthcare-associated (HA) infections, and
performed molecular characterization and antimicrobial susceptibility
tests of MRSA isolates.
Results: MRSA accounted for 25.5% of CA S. aureus infections and 67.4%
of HA infections. Predominant clones of CA-MRSA isolates were
ST59-MRSA-SCCmec type IV-spa type t437, ST30-MRSA-SCCmec type IV-spa
type t019 and ST72-MRSA-SCCmec type IV-spa type t324. Previously
established nosocomial MRSA strains including sequence type (ST) 239
and ST5 clones were found among CA-MRSA isolates from patients without
any risk factors for HA-MRSA infection. CA-MRSA clones such as ST59,
ST30 and ST72 were also isolated from patients with HA infections.
Conclusions: Our findings confirmed that MRSA infections in the
community have been increasing in Asian countries. Data also suggest
that various MRSA clones have spread between the community and
hospitals as well as between countries.
UT WOS:000289584000018
SN 0305-7453
doi 10.1093/jac/dkr024

Publication type J
Title Transforming health professionals’ education
Author/s Cristobal, F Worley, P
Journal source LANCET
Vol 377
Issue 9773
Start page 1235
End page 1236
Publication year 2011
Times cited 0
UT WOS:000289597300020
SN 0140-6736

Publication type J
Title Compiling Market and Other Financial Data on Smallholder Forestry in
Leyte, the Philippines
Author/s Cedamon, E Harrison, S Herbohn, J Mangaoang, E
CT International Workshop on Figures for Forests
CY NOV 24-26, 2008
Vol 10
Issue 2
Start page 149
End page 162
Publication year 2011
Times cited 0
Abstract Data collection and maintenance of databases concerning smallholder
forestry presents special problems in developing countries. This paper
examines forestry data collection experiences in a series of research
projects in Leyte, Philippines, supported by the Australian Centre for
International Agricultural Research, and the prospects for developing
forestry accounting networks. A variety of financial data have been
collected in relation to seedling production, plantation performance
and timber marketing. Seedling production cost and revenue data have
been obtained through snapshot surveys conducted in 2002 and 2008, and
repeated attempts have been made to estimate financial returns from
growing the most popular tree species. Diverse sources have been
identified for timber market information. On the supply side, these
include government records of registered plantations, obtaining
inventory data from barangay (community) leaders, and reporting
information about timber available for harvest on community notice
boards. On the demand side, official records of registered timber
merchants have been accessed, a detailed survey of timber processors
has been conducted, and estimates are being made of apparent per capita
timber consumption by district. Experiences in the Philippines
reinforce that the potential for forestry accounting networks is
limited by the resource-constrained situations of developing countries,
placing greater reliance on one-off surveys. Use of pre-existing local
networks and institutional structures offers potential for routine
collection of forestry data, such as through barangay (village) leaders
in the Philippines.
UT WOS:000289628800003
SN 1873-7617
doi 10.1007/s11842-010-9115-1

Publication type J
Title Impact of the alternate wetting and drying (AWD) water-saving
irrigation technique: Evidence from rice producers in the Philippines
Author/s Rejesus, RM Palis, FG Rodriguez, DGP Lampayan, RM Bouman, BAM
Journal source FOOD POLICY
Vol 36
Issue 2
Start page 280
End page 288
Publication year 2011
Times cited 0
Abstract This article evaluates the impacts of a controlled irrigation technique
in rice production called alternate wetting and drying (AWD).
Propensity score matching (PSM) and regression-based approaches applied
to farm-level survey data are used to achieve the objective of the
study. The PSM and regression-based approach accounts for the potential
bias due to selection problems from observable variables. Results of
the impact analysis using both empirical approaches indicate that AWD,
particularly the “Safe AWD” variant, reduces the hours of irrigation
use (by about 38%), without a statistically significant reduction in
yields and profits. This reduction in irrigation time translates to
corresponding savings in the amount of irrigation water and pumping
energy used. However, further analysis of the impact estimates suggests
that the potential magnitude of the selection bias based on
unobservable variables may still be able to eliminate the measured
impact from the PSM and regression-based techniques that only control
for selection based on observable variables. Hence, the current impact
results have to be interpreted with caution and further data collection
is needed to construct a panel data that would allow one to account for
selection problems due to unobservable variables and, consequently,
better estimate the AWD impact. (C) 2010 Elsevier Ltd. All rights
UT WOS:000289340500021
SN 0306-9192
doi 10.1016/j.foodpol.2010.11.026

Publication type J
Title Distribution and genetic diversity of begomoviruses infecting tomato
and pepper plants in the Philippines
Author/s Tsai, WS Shih, SL  Venkatesan, SG Aquino, MU Green, SK Kenyon, L Jan, FJ
Vol 158
Issue 3
Start page 275
End page 287
Publication year 2011
Times cited 0
Abstract Begomoviruses were found to be the major viruses infecting tomato
plants in the Philippines based on the surveys conducted from 2005 to
2006. Pepper-infecting begomoviruses were also detected. Isolates of
four distinct begomovirus species, Ageratum yellow vein virus (AYVV),
Tomato leaf curl Cebu virus (ToLCCeV), Tomato leaf curl Mindanao virus
(ToLCMiV) and Tomato leaf curl Philippines virus (ToLCPV), were
characterised at the DNA sequence level by comparing 20 DNA-As from
tomato samples comprising 13 from Luzon, 2 from Cebu and 5 from
Mindanao Islands, along with 3 DNA-As from pepper samples, 1 each from
Luzon, Cebu and Mindanao Islands. Two of these species (ToLCCeV and
ToLCMiV) were distinct novel begomoviruses, while AYVV was detected for
the first time in the Philippines. By geographic distribution, two
tomato begomoviruses (ToLCPV and ToLCCeV) were detected in Luzon and
Cebu Islands. The ToLCMiV was also detected in Luzon Island. The three
tomato begomoviruses, AYVV, ToLCCeV and ToLCMiV, were detected in
Mindanao Island. A ToLCPV isolate infecting pepper was also detected in
Luzon Island, while ToLCCeV was detected in pepper samples from Cebu
and Mindanao Islands. The diversity of viruses and their distinct
geographic distribution need to be taken into consideration in the
development and deployment of resistance against begomoviruses in the
Philippines. Strategies for the use of post-transcriptional gene
silencing for the control of tomato-infecting begomoviruses in the
Philippines are discussed.
UT WOS:000289637300006
SN 0003-4746
doi 10.1111/j.1744-7348.2011.00462.x

Publication type J
Title Fuzzy Optimization Model for Source-Sink Water Network Synthesis with
Parametric Uncertainties
Author/s Tan, RR
Vol 50
Issue 7
Start page 3686
End page 3694
Publication year 2011
Times cited 1
Abstract Source-sink problems occur in various process systems engineering
applications, such as the design of water reuse systems and resource
conservation networks. Such problems may be solved using alternative
approaches, including graphical pinch analysis and linear programming.
In most cases, it is normally assumed that the stream flow rates and
quality levels are deterministic. This paper presents a fuzzy
mathematical programming model for the synthesis of water networks when
the model parameters exhibit fuzzy uncertainties. The modeling approach
is illustrated for three water network case studies adapted from
literature. These illustrative examples cover concentration- and
property-based stream quality indices, as well as single- and
multiple-plant water integration.
UT WOS:000288833700006
SN 0888-5885
doi 10.1021/ie101025p

Publication type J
Title Preservation of larval bivalve shells in a radiolarian chert in the
Late Triassic (Early Norian) interval of the Malampaya Sound Group,
Calamian Island, western Philippines
Author/s Onoue, T Nikaido, T Zamoras, LR Matsuoka, A
Vol 79
Issue 1-2
Start page 58
End page 65
Publication year 2011
Times cited 0
Abstract Silicified thin larval bivalve shells occur in Upper Triassic
radiolarian chert (Early Norian) in the Liminangcong Formation of the
Malampaya Sound Group, part of a Late Jurassic to Early Cretaceous
subduction-related accretionary complex in the North Palawan Block,
western Philippines. The bivalve-bearing radiolarian chert, which we
term “bivalve chert,” is considered to be a deep-sea sediment that
accumulated in an open-ocean realm of the Panthalassa Ocean.
Radiolarian and conodont biostratigraphies indicate an early Norian
deposition of the thin-shelled bivalves. The bivalve morphology, thin
shells (less than 30 mu m thick), smooth ornamentation, and small size
(less than 1.3 mm long), suggests they represent larval shells.
Although their taxonomic identity cannot be established with certainty,
halobiid bivalves that lived in Norian times apparently had such a
planktonic larval mode of life. (C) 2011 Elsevier B.V. All rights
UT WOS:000289661900006
SN 0377-8398
doi 10.1016/j.marmicro.2011.01.005

Publication type J
Title Flying with Two Wings?: Justice and Gender in Vanuatu
Author/s Jolly, M
Vol 12
Issue 2
Start page 195
End page 201
Publication year 2011
Times cited 0
Abstract Miranda Forsyth’s book offers a lucid account of the relation between
state and non-state systems of justice in Vanuatu, as prospectively
like a ‘bird that flies with two wings’. It is equally informed by a
strong command of the theory and practice of legal pluralism and the
history and anthropology of Vanuatu. While acknowledging the complex
diversities of the archipelago it affords a national but not a
state-centric perspective. But how realistic is this image of the
future complementarity and parity between kastom and state justice, and
how might the challenges of gender hierarchy and gender violence skew
that hope of flying with two wings?.
UT WOS:000289251400006
SN 1444-2213
doi 10.1080/14442213.2011.548305

Publication type J
Title Quality of life in Leprosy patients assessed by the WHO-QOL finds
social aspect of life most affected
Author/s Mendoza, CG Dela Serna-Mah, AM Teresita, M Gabriel, G
Vol 52
Start page 34
End page 34
Publication year 2011
Times cited 0
UT WOS:000289470400098
SN 0004-8380

Publication type J
Author/s Jaluague, MM Porciuncula, CI Villardo, MM Estacio, RH
Vol 147
Start page S123
End page S123
Publication year 2011
Times cited 0
UT WOS:000289284500232
SN 0167-5273

Publication type J
Author/s Jaluague, MM
Vol 147
Start page S137
End page S138
Publication year 2011
Times cited 0
UT WOS:000289284500269
SN 0167-5273

Publication type J
Title Positive Antibody Response to Vaccination in Adolescence Predicts Lower
C-Reactive Protein Concentration in Young Adulthood in the Philippines
Author/s McDade, TW Adair, L Feranil, AB Kuzawa, C
Vol 23
Issue 3
Start page 313
End page 318
Publication year 2011
Times cited 0
Abstract Objectives: Inflammation has been associated with a wide range of
chronic degenerative diseases, but the developmental factors
contributing to the regulation of inflammation are poorly understood.
This study investigates the within-individual association between
antibody response to vaccination in adolescence and C-reactive protein
(CRP) concentration in young adulthood.
Methods: In 1998-99, at age 14-15 years, a subset of participants (N =
96) in the Cebu Longitudinal Health and Nutrition Survey were
administered a typhoid vaccine, and baseline and follow-up blood
samples were drawn to assess the strength of the antibody response to
vaccination. In 2005, at age 20-21 years, blood samples were drawn from
the full cohort for measurement of CRP. N = 74 individuals had complete
data at both time points. Bivariate associations and multivariate
logistic regression models were evaluated to test the hypothesis that
vaccine responsiveness in adolescence was significantly associated with
CRP level in young adulthood.
Results: There was a strong and statistically significant association
between antibody response to vaccination in adolescence and CRP in
young adulthood. Median CRP was more than four times higher among
nonresponders than responders, and nonresponders were 2.3 to 3.6 times
more likely to have CRP in the top tertile of the sample distribution.
Conclusions: This study provides evidence for a prospective,
within-individual link between more effective antibody-mediated immune
defenses and lower levels of inflammation. In the context of prior
research in this population, these results suggest that early
environments are important determinants of multiple aspects of an
individual’s immuno- phenotype. Am. J. Hum. Biol. 23: 313-318, 2011.
(c) 2010 Wiley-Liss, Inc.
UT WOS:000289354700004
SN 1042-0533
doi 10.1002/ajhb.21128

Publication type J
Title Changes in safety attitude and relationship to decreased postoperative
morbidity and mortality following implementation of a checklist-based
surgical safety intervention
Author/s Haynes, AB Weiser, TG Berry, WR Lipsitz, SR Breizat, AHS Dellinger, EP Dziekan, G Herbosa, T Kibatala, PL Lapitan, MCM Merry, AF Reznick, RK Taylor, B Vats, A Gawande, AA
Journal source BMJ QUALITY & SAFETY
Vol 20
Issue 1
Start page 102
End page 107
Publication year 2011
Times cited 0
Abstract Objectives: To assess the relationship between changes in clinician
attitude and changes in postoperative outcomes following a
checklist-based surgical safety intervention.
Design: Pre- and post intervention survey.
Setting: Eight hospitals participating in a trial of a WHO surgical
safety checklist.
Participants: Clinicians actively working in the designated study
operating rooms at the eight hospitals.
Survey instrument: Modified operating-room version Safety Attitudes
Questionnaire (SAQ).
Main outcome measures: Change in mean safety attitude score and
correlation between change in safety attitude score and change in
postoperative outcomes, plus clinician opinion of checklist efficacy
and usability.
Results: Clinicians in the preintervention phase (n=281) had a mean SAQ
score of 3.91 (on a scale of 1 to 5, with 5 representing better safety
attitude), while the postintervention group (n=257) had a mean of 4.01
(p=0.0127). The degree of improvement in mean SAQ score at each site
correlated with a reduction in postoperative complication rate
(r-0.7143, p=0.0381). The checklist was considered easy to use by 80.2%
of respondents, while 19.8% felt that it took a long time to complete,
and 78.6% felt that the programme prevented errors. Overall, 93.4%
would want the checklist used if they were undergoing operation.
Conclusions: Improvements in postoperative outcomes were associated
with improved perception of teamwork and safety climate among
respondents, suggesting that changes in these may be partially
responsible for the effect of the checklist. Clinicians held the
checklist in high regard and the overwhelming majority would want it
used if they were undergoing surgery themselves.
UT WOS:000289726400014
SN 2044-5415
doi 10.1136/bmjqs.2009.040022

Publication type J
Title Initial combination therapy with saxagliptin and metformin provides
sustained glycaemic control and is well tolerated for up to 76 weeks
Author/s Pfutzner, A Paz-Pacheco, E Allen, E Frederich, R Chen, RCV
Vol 13
Issue 6
Start page 567
End page 576
Publication year 2011
Times cited 0
Abstract Methods: In this phase 3, parallel-group, double-blind,
active-controlled study, 1306 patients 18-77 years of age (HbA1c
8.0-12.0%) were randomized to saxagliptin 5 mg + 500 mg metformin,
saxagliptin 10 mg + 500 mg metformin, saxagliptin 10 mg + placebo or
500 mg metformin + placebo. Blinded metformin was titrated during weeks
1-5 of the short-term treatment period in 500 mg/day increments to 2000
mg/day maximum in the metformin-based treatment groups. No titration of
metformin was permitted during the long-term treatment period. A total
of 888 patients completed the study (76 weeks), 613 without being
rescued. Changes in HbA1c, fasting plasma glucose, 120-min postprandial
glucose (PPG) and PPG-area under the curve (AUC) from baseline to week
76 were analysed using a repeated-measures model.
Results: At 76 weeks, adjusted mean changes from baseline HbA1c (95%
CI) for saxagliptin 5 mg + metformin, saxagliptin 10 mg + metformin,
saxagliptin 10 mg and metformin were -2.31 (-2.44, -2.18), -2.33
(-2.46, -2.20), -1.55 (-1.70, -1.40) and -1.79% (-1.93, -1.65),
respectively (post hoc and nominal p < 0.0001 vs. metformin and
saxagliptin monotherapies for saxagliptin 5 mg + metformin and
saxagliptin 10 mg + metformin). The proportions of patients requiring
rescue or discontinuation for insufficient glycaemic control were lower
for saxagliptin + metformin than for either monotherapy. Little or no
attenuation in PPG-AUC or 120-min PPG was observed between weeks 24 and
76 for saxagliptin + metformin, indicating persistent efficacy. Adverse
event rates were similar across groups; hypoglycaemic events occurred
at a low frequency.
Conclusion: Saxagliptin + metformin initial combination therapy was
well tolerated and produced sustained glycaemic control for up to 76
weeks, with greater improvements in glycaemic parameters compared with
either drug alone.
UT WOS:000289731100012
SN 1462-8902
doi 10.1111/j.1463-1326.2011.01385.x

Publication type J
Title Compensatory Growth of Ludwigia (Ludwigia hyssopifolia) in Response to
Interference of Direct-Seeded Rice
Author/s Chauhan, BS Pame, ARP Johnson, DE
Journal source WEED SCIENCE
Vol 59
Issue 2
Start page 177
End page 181
Publication year 2011
Times cited 0
Abstract Ludwigia is an important broadleaf weed of direct-seeded rice in Asia.
Crop interference that relies on shading may have potential as a
component of integrated weed management strategies but it requires
understanding the extent to which rice can interfere with weed growth
and how these weeds may respond. The growth of ludwigia was studied
when grown alone and in competition with 4 and 12 rice (cv. IR72)
plants. Rice interference reduced ludwigia height, number of branches,
and shoot and root biomass. However, ludwigia showed the ability to
reduce the effects of rice interference by increasing leaf weight
ratio, increasing stem and leaf biomass in the upper half of the plant,
and increasing specific stem length. At 11 wk after seeding, for
example, ludwigia grown with 12 rice plants had 38% greater leaf weight
ratio compared to plants grown alone. When grown with 12 rice plants,
the weed had 82% of its leaf biomass in upper half of the plant
compared to only 25% in weeds grown alone. The results showed that
ludwigia responded to rice interference with a combination of
adaptations typical of many weed species. Despite such plasticity, the
control of ludwigia may be achieved by dense rice stands and increasing
UT WOS:000289808400006
SN 0043-1745
doi 10.1614/WS-D-10-00134.1

Publication type J
Title Seed Germination Ecology of Itchgrass (Rottboellia cochinchinensis)
Author/s Bolfrey-Arku, GEK Chauhan, BS Johnson, DE
Journal source WEED SCIENCE
Vol 59
Issue 2
Start page 182
End page 187
Publication year 2011
Times cited 0
Abstract Itchgrass is a weed of many crops throughout the tropics and one of the
most important grass weeds of rainfed rice. Experiments were conducted
in the laboratory and screenhouse to determine the effects of light,
alternating day/night temperatures, high temperature pretreatment,
water stress, seed burial depth, and rice residue on seed germination
and seedling emergence of itchgrass in the Philippines. Two populations
were evaluated and the results were consistent for both populations.
Germination in the light/dark regime was greater at alternating
day/night temperatures of 25/15 C than at 35/25, 30/20, or 20/10 C.
Light was not a requirement for germination, but a light/dark regime
increased germination by 96%, across temperature and population. A
5-min high temperature pretreatment for 50% inhibition of maximum
itchgrass germination ranged from 145 to 151 C with no germination when
seeds were exposed to >= 180 C. The osmotic potential required for 50%
inhibition of maximum germination was -0.6 MPa for itchgrass, although
some seeds germinated at -0.8 MPa. Seedling emergence was greatest for
seeds placed on the soil surface, and emergence declined with
increasing soil burial depth; no seedlings emerged from seeds buried at
10 cm. The addition of rice residue to soil surface in pots at rates
equivalent to 4 to 6 Mg ha(-1) reduced itchgrass seedling emergence.
Since seedling emergence was greatest at shallow depths and germination
was stimulated by light, itchgrass may become a problem in systems
where soil is cultivated at shallow depths. Knowledge gained in this
study could contribute to developing components of integrated weed
management strategies for itchgrass.
UT WOS:000289808400007
SN 0043-1745
doi 10.1614/WS-D-10-00095.1

Publication type J
Title Laparoscopic partial nephrectomy: six degrees of haemostasis
Author/s Louie, MK Deane, LA Kaplan, A GLee, HJ Box, GN Abraham, JBA Borin, JF Khan, F McDougall, EM Clayman, RV
Vol 107
Issue 9
Start page 1454
End page 1459
Publication year 2011
Times cited 0
To describe six steps for haemostasis and collecting system closure
(‘six degrees of haemostasis’) that are reproducible and that minimize
the two most concerning complications of laparoscopic partial
nephrectomy: haemorrhage and urine leakage.
A retrospective study of 23 consecutive laparoscopic partial
nephrectomy cases performed by a single surgeon between 2005 and 2008
using the ‘six degrees of haemostasis’ was carried out.
There were no cases of intraoperative, postoperative or delayed
There were no cases of urine leakage.
The ‘six degrees of haemostasis’ technique for laparoscopic partial
nephrectomy described in the present study provides a reliable and
reproducible method to reassure the surgeon of haemostasis and provide
a decreased risk of urine leakage.
UT WOS:000289739400022
SN 1464-4096
doi 10.1111/j.1464-410X.2010.09651.x

Publication type J
Title Micro-pulling-down-method-grown Ce:LiCAF crystal for side-pumped laser
Author/s Kouno, M Gabayno, JL Cadatal-Raduban, M Pham, M Yamanoi, K Estacio, E Garcia, W Nakazato, T Shimizu, T Sarukura, N Suyama, T Fukuda, K Kim, KJ Yoshikawa, A Saito, F
CT 16th International Conference on Crystal Growth (ICCG16)/14th
International Conference on Vapor Growth and Epitaxy (ICVGE14)
CY AUG 08-13, 2010
Vol 318
Issue 1
Start page 737
End page 740
Publication year 2011
Times cited 0
Abstract We demonstrate 290 nm lasing and femtosecond amplification using a
micro-pulling-down method-grown Ce:LiCaAlF6 crystal, which was excited
using dual-side- and four-side-pumping schemes. These results show that
the flexibility and lower cost of this growth technique as well as the
multi-side pumping configurations provide good prospects for high-power
ultraviolet generation that will enhance the applications of the
Ce:LiCaAlF6 laser and amplifier. (C) 2010 Elsevier B.V. All rights
UT WOS:000289653900161
SN 0022-0248
doi 10.1016/j.jcrysgro.2010.12.049

Publication type J
Author/s Ravanes, JM Cellona, RV Balagon, M Abalos, RM Walsh, GP Walsh, DS
Vol 42
Issue 2
Start page 323
End page 330
Publication year 2011
Times cited 0
Abstract The aim of this study was to describe the ocular conditions in
multi-bacillary (MB) leprosy patients treated with 2 year WHO multiple
drug therapy (MDT), consisting of dapsone, clofazimine and rifampin, a
regimen expected to reduce ocular complications of leprosy. We
conducted comprehensive eye examinations in 202 Filipino MB leprosy
patients before, during, and after WHO 2 year MDT. Assessments were
carried out for at least 5 years. Inflammatory “lepra” reactions
occurred in 62% (reversal reaction, 52%; erythema nodosum leprosum,
10%); most were mild. Eye abnormalities consisted mostly of diminished
corneal sensitivity before MDT (6%) and lagopthalmos (n = 7,3.4%). Six
of 7 lagopthalmos cases occurred in a subset of 132 patients with
facial patches (5%). Visual acuity scores, intra-ocular pressures and
pupil cycle times were unremarkable. Bacillary invasion, keratitis,
episcleritis, iridocyclitis, ectropion, synechiae, glaucoma and
cataract formation were not detected. Scleral clofazimine pigmentation
was frequent, resolving in most within 3 years of treatment cessation.
Facial patches at presentation may denote a higher risk for
lagopthalmos. We propose the generally low rates of ocular problems
reflected mild lepra reactions, due to anti-inflammatory properties of
clofazimine, a relatively young cohort, and a readily accessible
community-based clinic permitting earlier diagnosis and prompt
UT WOS:000289862000012
SN 0125-1562

Publication type J
Title Leprosy in the Philippines: a review
Author/s Handog, EB Gabriel, MTG Co, CC
Vol 50
Issue 5
Start page 573
End page 581
Publication year 2011
Times cited 0
Abstract Leprosy is a skin disease that accounts for serious deformities and
disabilities, leading to stigmatization and psychosocial suffering. It
is included in “The Neglected Tropical Diseases”. Not surprisingly, its
management is increasingly reported as a function of Dermatology
Departments, with a strong community-orientated bias. Prompt and
accurate diagnosis of leprosy is crucial in the control of leprosy. Its
management requires a multidisciplinary team of skilled physicians,
laboratory staff, and nurses. All members of the health sectors should
remain vigilant to combat this battle against leprosy.
UT WOS:000289832300015
SN 0011-9059
doi 10.1111/j.1365-4632.2011.05044.x

Publication type J
Title The prognostic factors of recurrent GCT: a cooperative study by the
Eastern Asian Musculoskeletal Oncology Group
Author/s Takeuchi, A Tsuchiya, H Niu, XH Ueda, T Jeon, DG Wang, EHM Asavamongkolkul, A Kusuzaki, K Sakayama, K Kang, YK
Vol 16
Issue 2
Start page 196
End page 202
Publication year 2011
Times cited 0
Abstract Background Giant-cell tumor (GCT) of bone is a common primary benign
tumor with high local recurrence and potential distant metastasis or
malignant transformation. We have investigated the clinical behavior of
recurrent GCT of bone in the extremities.
Methods We retrospectively reviewed 110 patients with recurrent GCTs of
bone in the extremities treated by the Eastern Asian Musculoskeletal
Oncology Group. The factors that affected the number of recurrences and
distant metastasis were analyzed.
Results The median interval between initial surgery and the first
recurrence of GCT was 16 months (2-180 months). All patients received
additional surgery for first recurrence. Twenty-five patients had a
second recurrence and 6 patients had a third recurrence. The mean
interval between the initial surgery and the first recurrence
correlated with the eventual number of recurrences-14.1 months for the
repeated recurrence groups (two and three recurrences) and 28.3 months
for the single recurrence group (p = 0.016). Campanacci grade did not
correlate with repeated recurrence (p = 0. 446). The venue of the
initial surgery did not correlate with recurrence but did affect
preservation of the adjacent joint (chi-squared test; p = 0.046).
Campanacci grade II and III also correlated with sacrifice of the
adjacent joint (p = 0.020). The incidence of lung metastasis and
malignant transformation were 7.5% (8 out of 107 patients) and 2.7% (3
out of 110 patients), respectively. Repeat recurrence was associated
with lung metastasis (p = 0.018).
Conclusions Early local recurrence of GCT is a risk factor for repeat
recurrence. Repeat recurrence also correlates with lung metastasis.
Recurettage with meticulous adjuvant treatment to completely preclude
recurrent lesions is a reasonable method for preserving the adjacent
joint. However, a continuous careful follow-up is mandatory.
UT WOS:000289849800010
SN 0949-2658
doi 10.1007/s00776-011-0030-x

Publication type J
Title Priority actions for the non-communicable disease crisis
Author/s Beaglehole, R Bonita, R Horton, R Adams, C Alleyne, G Asaria, P Baugh, V Bekedam, H Billo, N Casswell, S Cecchini, M Colagiuri, R Colagiuri, S Collins, T Ebrahim, S Engelgau, M Galea, G Gaziano, T Geneau, R Haines, A Hospedales, J Jha, P Keeling, A Leeder, S Lincoln, P McKee, M Mackay, J Mgnusson, R Moodie, R Mwatsama, M Nishtar, S Norrving, B Patterson, D Piot, P Ralston, J Rani, M Reddy, KS Sassi, F Sheron, N Stuckler, D Suh, I Torode, J Varghese, C Watt, J
Journal source LANCET
Vol 377
Issue 9775
Start page 1438
End page 1447
Publication year 2011
Times cited 0
Abstract The UN High-Level Meeting on Non-Communicable Diseases (NCDs) in
September, 2011, is an unprecedented opportunity to create a sustained
global movement against premature death and preventable morbidity and
disability from NCDs, mainly heart disease, stroke, cancer, diabetes,
and chronic respiratory disease. The increasing global crisis in NCDs
is a barrier to development goals including poverty reduction, health
equity, economic stability, and human security. The Lancet NCD Action
Group and the NCD Alliance propose five overarching priority actions
for the response to the crisis leadership, prevention, treatment,
international cooperation, and monitoring and accountability and the
delivery of five priority interventions tobacco control, salt
reduction, improved diets and physical activity, reduction in hazardous
alcohol intake, and essential drugs and technologies. The priority
interventions were chosen for their health effects, cost-effectiveness,
low costs of implementation, and political and financial feasibility.
The most urgent and immediate priority is tobacco control. We propose
as a goal for 2040, a world essentially free from tobacco where less
than 5% of people use tobacco. Implementation of the priority
interventions, at an estimated global commitment of about US$9 billion
per year, will bring enormous benefits to social and economic
development and to the health sector. If widely adopted, these
interventions will achieve the global goal of reducing NCD death rates
by 2% per year, averting tens of millions of premature deaths in this
UT WOS:000289963000033
SN 0140-6736
doi 10.1016/S0140-6736(11)60393-0

Publication type J
Author/s Alegria, FC Tiglao, NMC
Vol 18
Issue 1
Start page 3
End page 12
Publication year 2011
Times cited 0
Abstract The Histogram Test method is a popular technique in analog-to-digital
converter (ADC) testing. The presence of additive noise in the test
setup or in the ADC itself can potentially affect the accuracy of the
test results. In this study, we demonstrate that additive noise causes
a bias in the terminal based estimation of the gain but not in the
estimation of the offset. The estimation error is determined
analytically as a function of the sinusoidal stimulus signal amplitude
and the noise standard deviation. We derive an exact but
computationally difficult expression as well as a simpler closed form
approximation that provides an upper bound of the bias of the terminal
based gain. The estimators are validated numerically using a Monte
Carlo procedure with simulated and experimental data.
UT WOS:000289491200001
SN 0860-8229

Publication type J
Title Diversity Analysis of Philippine Bananas Using Simple Sequence Repeats
Author/s Dacumos, CN Lalusin, AG Namuco, LO Patena, LF Barba, RC
Vol 36
Issue 1
Start page 1
End page 10
Publication year 2011
Times cited 0
Abstract Simple Sequence Repeats (SSRs) were used to determine the genetic
variability and relationships among sixty-one genotypes of Philippine
bananas. Ten out of twelve primer pairs tested were found to be
polymorphic and generated 43 alleles ranging from 3 to 13 alleles per
primer. Seven out of the ten primers gave unique bands for some of the
genotypes tested showing their potential use in cultivar identification
and fingerprinting. The resolving power of molecular markers measured
as the Polymorphism Information Content (PIC) ranged from 0.68 to 0.94.
Cluster analysis at the 83.1% similarity divided the dendrogram into 11
clusters with several outliers indicating a wide genetic variation
existing within the different Musa genotypes. Cluster analysis
separated the genotypes of Musa acuminata from other genotypes with A
and B genomes although no cohesive clustering among different groups.
(i.e. diploids, triploids, and tetraploids) was observed.
UT WOS:000289749300001
SN 0115-463X

Publication type J
Title Assessment of Ploidy and Genome Constitution of Some Musa balbisiana
Cultivars using DArT Markers
Author/s Sales, EK Butardo, NG Paniagua, HG Jansen, H Dolezel, J
Vol 36
Issue 1
Start page 11
End page 18
Publication year 2011
Times cited 0
Abstract The Philippines is one of the centers of origin and diversity for
bananas. There is an endless range of names and synonyms for cultivars,
thus the major constraint in banana and plantain research is on proper
identification and classification. Musa balbisiana is grown extensively
and considered endemic in the Philippines. However, there are opposing
views as to the genomic constitution of cultivars. Philippine and other
Asian Musa experts claimed that Philippine ‘Saba’ group is of the
triploid B but American and European Musa workers denied the existence
of such and consistently claimed that it is hybrids of A and B genomes.
The objective of the study was to determine if Diversity Array
Technology (DArT) analysis can efficiently verify the genome
constitution of the Musa cultivars in question. Twenty-four Philippine
Musa cultivars were subjected to flow cytometry analysis for ploidy
confirmation and DArT analysis for molecular characterization. Results
of the flow cytometry analysis confirmed the triploidy of the
Philippine ‘Saba’ group while the molecular data showed that some DArT
markers were specific for the B genome such that these markers can
identify the cultivars with B genome regardless of the presence of A
genome. Hence these markers can be used to establish genome identity of
the Musa cultivars. Likewise, dendrogram constructed by Mega version 4
clearly separated the BB/BBB cultivars from AA/AAA and AAB cultivars.
Moreover, the dendrogram showed that most of these putative BBB
cultivars grouped as a separate cluster from the AAA and AAB groups.
Bootstrapping all the more enhanced these groupings, and strongly
supported the existence of a pure Balbisiana group. These confirmed the
Asian claims of the triploid B nature of the Philippine ‘Saba’ group.
However, two cultivars namely ‘Inambak’ and ‘Pondol’ (assumed to be of
the BBB type) formed a cluster with the AAB (cv’Tindok and ‘Latundan’).
This suggests therefore, that these two Phil. Musa cultivars could be
AAB unlike the rest of the cultivars claimed to be triploid B.
UT WOS:000289749300002
SN 0115-463X

Publication type J
Title Rapid Evaluation Protocol for Hydrogen Peroxide and Ultraviolet
Radiation Resistance using Lesion Mimic Mutant rice (Oryza sativa L.)
Author/s Manigbas, NL Park, DS Park, SK Kim, SM Hwang, WH Wang, HJ Kang, SG Kang, HW Yi, G
Vol 36
Issue 1
Start page 19
End page 27
Publication year 2011
Times cited 0
Abstract Ultraviolet (UV) radiation can induce an increase in hydrogen peroxide
(H2O2) production which could both inflict injury to crops affecting
growth and productivity. Responses of plants to UV and H2O2 may vary
not only among species but also among cultivars. A protocol for
screening UV and H2O2 resistance was developed using lesion mimic
mutant (LMM) rice lines to detect resistant rice breeding lines related
to abiotic stresses where H2O2 is involved. To date, there is no
standard method or protocol yet that has been defined for the rapid and
reliable detection of resistant rice lines using UV and H2O2. Screening
under field conditions is difficult due to plant and soil interactions,
soil heterogeneity, land and labor resources, and uncontrollable
environmental effects such as temperature, humidity, rainfall, and
solar radiation/duration. Thus, a rapid and reproducible laboratory
protocol for H2O2 and UV radiation is necessary to reduce time and
resources with desirable outputs. LMM rice lines were preferably used
than the cultivars since LMM are known to be more sensitive to stress
signals and spontaneously develop necrotic lesions when subjected to
environmental stresses. Rice seedlings were subjected to 50, 100, 200,
400, 600, and 1000 mM H2O2 concentration for 3 d. This resulted to
different reaction of leaf browning and 600 mM H2O2 concentration was
selected to screen leaf and plant samples. For UV treatment, seedlings
were exposed to artificial UV light at 30 cm height. Results showed
that 3 out of 13 fully characterized lesion mimic mutant lines had 50%
survival under ultraviolet stress and 10 out of 52 other lesion mimic
mutants were found to be tolerant to H2O2 better than the wild type
Dongjin. Our investigation indicated that H2O2 could be used as
selectable marker in the early detection of resistant lines to related
abiotic stresses where H2O2 has been involved. H2O2 is known as a
regulatory molecule in stress perception and signal transduction.
UT WOS:000289749300003
SN 0115-463X

Publication type J
Title Genetic Variability Potential and Morphometric Characteristics of Five
Geographic Populations of Oryza meyeriana (Zoll. et Mor. ex. Steud.)
Baill. Found in the Philippines
Author/s Bon, SG Borromeo, TH Altoveros, NC
Vol 36
Issue 1
Start page 28
End page 36
Publication year 2011
Times cited 0
Abstract This study was conducted on 5 Philippine populations of Oryza meyeriana
(Zoll. et Mor. ex. Steud.) Baill. presently available under ex situ
conservation to elucidate their phenotypic and isozyme characteristics
as well as their potential genetic variability structure based on 29
morphometric characteristic and 8 isozyme systems. Morphometric
characterization showed a range of phenotypic characteristics generally
conforming with published taxonomic description for the species, though
visually the population samples can be differentiated by provenance.
The population samples were polymorphic in 5 qualitative descriptors
and assume ranges of quantitative values generally conforming with
published taxonomic descriptions. Zymogram patterns for Alanine
aminopeptidase, Isocitrate dehydrogenase, Endopeptidase, Shikimate
dehydrogenase, Glutamic oxaloacetate transaminase and Phosphogluconate
isomerase strongly suggest inherent substantial genetic variability
among the wild populations tested with 6 isozymes being polymorphic.
However, isozyme pattern was not strongly correlated with phenotypic
characteristics or provenance. Cluster analysis indeed indicated within
sample and between sample differences and similarities. Qualitatively,
Palawan samples showed discreetly different morphotypes but share
values within a common range for quantitative characters.
Multi-dimensional scaling confirms the aggregation of Palawan
population as well as the geographic separation of Sorsogon and Nueva
Vizcaya populations. Results therefore have substantially demonstrated
significant genetic diversity potential of O. meyeriana populations
occurring in the Philippines. Further, phenotypic and isozyme
characterization have shown that the local populations were composed of
diverse morphotypes, where genetic diversity maybe expressed both
between and within geographic populations. Recommendations for finer
and wider analysis of genetic structure in support of developing
genetically effective conservation approach for the local populations
of O. meyeriana were suggested.
UT WOS:000289749300004
SN 0115-463X

Publication type J
Title Agronomic Response of Lowland Rice PSB Rc 18 (Oryza sativa L.) to
Different Water, Spacing and Nutrient Management
Author/s Escasinas, RO Zamora, OB
Vol 36
Issue 1
Start page 37
End page 46
Publication year 2011
Times cited 0
Abstract A field experiment was conducted for PSB Rc 18 in two cropping seasons
at the experimental area of the Department of Agronomy and Soil
Science, Visayas State University, Visca, Baybay, Leyte to examine the
agronomic responses of lowland rice grown under different water,
spacing and nutrient management. The wet season cropping was from 8
November 2007 to 29 February 2008 while the dry season cropping was
from 14 April to 17 August 2008.
Different sources of fertilizers were designated as the mainplot and
plant spacing as the subplot nested within 2 water regimes i.e.
continuous flooding (conventional) and no flooding (soil was saturated
but not flooded). Lowland rice may not need continuous flooding in
order to produce high grain yield. Yield of PSB Rc 18 under non flooded
condition was significantly higher than under continuous flooding water
management system by 12-15% with water saving of 52-53%. This is
applicable in high rainfall areas such as in the Visayas State
University. Reduced plant height was recorded under no flooding
condition, a characteristic that imparts resistance to lodging even at
high grain yield. Composted goat manure and compost mixture (G. sepium
+ goat manure + rice straw + carbonized rice hull) as organic
fertilizers gave similar. grain yield as inorganic fertilizer, implying
that these materials are viable alternatives to expensive inorganic
fertilizers. Plant spacing of 20 x 20 cm and 40 x 10 cm did not differ
significantly in most agronomic characteristics as well as grain yield.
However, in 20 x 20 cm spacing, transplanting and weeding were managed
with less difficulty. Hence, 20 x 20 cm spacing is the appropriate
distance of planting for optimum grain yield of PSB Rc 18 under organic
production system. The treatment combination of no flooding,
application of goat manure and closer spacing of 20 x 20 cm was the
best combination that gave similar yield to PSB Rc 18 plants applied
with inorganic fertilizer at 90-30-30 kg ha(-1) NPK.
UT WOS:000289749300005
SN 0115-463X

Publication type J
Title Composting and Microbial Inoculation of Coconut Coir Dust-Chicken
Manure Mixture for Organic Fertilizer Use
Author/s Espiritu, BM
Vol 36
Issue 1
Start page 47
End page 56
Publication year 2011
Times cited 0
Abstract Coconut coir dust and chicken manure abound as agro-industrial wastes
in many parts of the country and their successful processing into
effective organic fertilizers could provide added income as well as
help in mitigating environmental pollution. This study explored the use
of composting and microbial inoculation to convert these materials,
into value-added inputs for agricultural production. Cultures of
Azotobacter sp. and/or Trichoderma sp. were inoculated into coconut
coir dust-chicken manure mixture (60/40, w/w) and this was composted
for a 28-d period under 3 conditions: flask composting without combined
N; flask-composting with 1% ammonium sulfate; and net-bag composting
embedded in actual compost heaps. Unsterile mixtures inoculated with
Azotobacter alone exhibited the highest weight loss and the highest N
gain in compost in flasks. Under actual composting, although
Azotobacter alone increased material degradation significantly over all
other treatments, the combined inoculation with Azotobacter and
Trichoderma promoted high carbon loss, high N gain and depression of
C/N ratio. Correlation showed total N increase was due more to nitrogen
fixation than to substrate decomposition. Microbial inoculation
enhanced the populations of target organisms in the resulting compost
Confirmation of the beneficial effects of inoculated coir dust-chicken
manure compost was done in a field test in lowland rice. Significant
grain yield increase over the control, as much as 30%, was obtained
with this kind of compost.
UT WOS:000289749300006
SN 0115-463X

Publication type J
Title “Betag”: First Locally-Bred NSIC-Approved Variety of Garden Pea (Pisum
sativum) for Commercialization in Benguet
Author/s Tandang, LL Kebasen, BA Amlos, BB Kimeu, AM Maghirang, RG
Vol 36
Issue 1
Start page 57
End page 61
Publication year 2011
Times cited 0
Abstract The project was undertaken to evaluate promising varieties of garden
pea developed at Benguet State University-Institute of Plant Breeding
Highland Crops Research Station and to identify potential varieties for
nomination and recommendation to the National Seed Industry Council
(NSIC) for release as new locally-bred variety of garden pea with
higher yield and better horticultural characteristics than the
commercial varieties for regional commercialization. Out of the 183
accessions collected from foreign sources, 23 were identified potential
parents. They were involved in hybridization program including existing
commercial varieties through pedigree method of breeding.
Characterization and evaluation were done among F-2 to F-6 segregating
populations. The top ten advanced breeding lines including the check
variety were identified as promising varieties. They were entered in
on-farm field trials in different locations in La Trinidad from
2006-2008 which resulted to official approval and registration of CLG
18A as NSIC 2008 GP1 with popular name “Betag” on November 20, 2008 by
the DA-NSIC as new improved garden pea variety for regional
commercialization in the Cordillera.
UT WOS:000289749300007
SN 0115-463X

Publication type J
Title Making Art and History Matter The Lopez Memorial Museum at Fifty
Author/s Benitez-Johannot, P
Journal source ARTS OF ASIA
Vol 41
Issue 2
Start page 118
End page 130
Publication year 2011
Times cited 0
UT WOS:000289763100011
SN 0004-4083

Publication type J
Title Identification of unknown ocular pathogens in clinically suspected eye
infections using ribosomal RNA gene sequence analysis
Author/s Daroy, MLG Lopez, JS Torres, BCL Loy, MJ Tuano, PMC Matias, RR
Vol 17
Issue 5
Start page 776
End page 779
Publication year 2011
Times cited 0
Abstract P>DNA sequence-based identification of pathogens from ocular samples of
patients with clinically suspected eye infections was accomplished
using 16S and internal transcribed spacer (ITS) ribosomal RNA gene
sequence analysis. PCR was positive for 24 of 99 samples tested. Both
culture and 16S rDNA sequence analysis identified Pseudomonas
aeruginosa, streptococci and Enterobacteriaceae. Isolates misidentified
as Burkholderia cepacia by biochemical tests were identified as
Ralstonia mannitolilytica by 16S rDNA sequence analysis. Sequence
analysis identified the following microorganisms from 19
culture-negative samples: Haemophilus influenzae, Sphingomonas sp.,
Klebsiella pneumoniae, Staphylococcus haemolyticus, Morganella
morganii, Mycobacterium sp., Chryseobacterium sp., Pseudomonas
saccharophila (Xanthomonas) and the fungus, Phaeoacremonium inflatipes.
UT WOS:000289891600024
SN 1198-743X
doi 10.1111/j.1469-0691.2010.03369.x

Publication type J
Title The Early Phase of an HIV Epidemic in a Population Exposed Previously
to HCV in the Philippines
Author/s Telan, EFO Samonte, GMJ Abellanosa-Tac-An, IP Alesna, ET Leano, PSA Emphasis, YEE Tsuneki, A Matsumoto, K Kageyama, S
Vol 83
Issue 6
Start page 941
End page 947
Publication year 2011
Times cited 0
Abstract Human immunodeficiency virus (HIV) sentinel surveillance program for
injecting drug users has been conducted in Metro Cebu, the Philippines.
A low prevalence (0-0.52%) of anti-HIV-positivity had been detected in
this population from 2002 to 2007. However, a 10-fold increase in HIV
prevalence was detected in the 2009 national HIV sentinel surveillance
program. It prompted an additional outreach program to be conducted in
Metro Cebu in January 2010, which recorded the highest HIV prevalence
rate ever documented in the Philippines (75%, 44/59). HIV genes from
fourteen 2009 to 2010 Metro Cebu strains were clustered closely in the
phylogenetic tree, but no other strain collected outside Metro Cebu and
none stored in the International Nucleotide Sequence Database was
allocated to the same phylogenetic cluster. All these HIV infections
have emerged in the anti-hepatitis C virus (HCV)-positive population
(100%, 62/62) in Metro Cebu from 2009 to 2010. The five HCV strains
from the individuals harboring the closely related HIV strains were
categorized into different subtypes. These results strongly suggest
that HIV infections occurred recently and spread rapidly among
injecting drug users, while HCV had been circulating previously among
them. Considering the fact that injecting drug use was the first mode
of HIV transmission in Asia, extensive monitoring of injecting drug
users and associated bridging populations is necessary. Therefore,
HCV-guided characterization of the spread of HIV to populations that
are vulnerable to blood-borne infections could play an important role
in alerting health authorities to the early phase of an HIV epidemic.
J. Med. Viral. 83:941-947, 2011. (C) 2011 Wiley-Liss, Inc.
UT WOS:000289960500003
SN 0146-6615
doi 10.1002/jmv.22070

Publication type J
Title Genome-Wide Association Study of Anthropometric Traits and Evidence of
Interactions With Age and Study Year in Filipino Women
Author/s Croteau-Chonka, DC Marvelle, AF Lange, EM Lee, NR Adair, LS Lange, LA Mohlke, KL
Journal source OBESITY
Vol 19
Issue 5
Start page 1019
End page 1027
Publication year 2011
Times cited 0
Abstract Increased values of multiple adiposity-related anthropometric traits
are important risk factors for many common complex diseases. We
performed a genome-wide association (GWA) study for four quantitative
traits related to body size and adiposity (BMI, weight, waist
circumference, and height) in a cohort of 1,792 adult Filipino women
from the Cebu Longitudinal Health and Nutrition Survey (CLHNS). This is
the first GWA study of anthropometric traits in Filipinos, a population
experiencing a rapid transition into a more obesogenic environment. In
addition to identifying suggestive evidence of additional
single-nucleotide polymorphism (SNP) association signals (P < 10(-5)),
we replicated (P < 0.05, same direction of additive effect)
associations previously reported in European populations of both BMI
and weight with MC4R and FTO, of BMI with BDNF, and of height with
EFEMP1, ZBTB38, and NPPC, but none with waist circumference. We also
replicated loci reported in Japanese or Korean populations as
associated with BMI (OTOL1) and height (HIST1H1PS2, C14orf145, GPC5). A
difference in local linkage disequilibrium (LD) between European and
Asian populations suggests a narrowed association region for BDNF,
while still including a proposed functional nonsynonymous amino acid
substitution variant (rs6265, Val66Met). Finally, we observed
significant evidence (P < 0.0042) for age-by-genotype interactions
influencing BMI for rs17782313 (MC4R) and rs9939609 (FTO), and for a
study year-by-genotype interaction for rs4923461 (BDNF). Our results
show that several genetic risk factors are associated with
anthropometric traits in Filipinos and provide further insight into the
effects of BDNF, FTO, and MC4R on BMI.
UT WOS:000289933300021
SN 1930-7381
doi 10.1038/oby.2010.256

Publication type J
Author/s Demeterio, FP
Vol 40
Issue 2
Start page 149
End page 169
Publication year 2011
Times cited 0
Abstract This paper is written to provide an aesthetic parameter to sensibly
analyze the controversy that arose after the naming of Carlo J. Caparas
as National Artist for Visual Arts and Film. By contextualizing Caparas
and his works in five clusters of aesthetic systems, namely,
traditional, modern, patronage, pseudo-modern, and postmodern, this
paper argues that there can never be a coherent, sustained, and
rational justification for the error committed by President Gloria
Macapagal-Arroyo in honoring him. The paper concludes with the note
that the aesthetic discourse on the controversy was unfortunately
converted into a legal discourse as a case was filed by some National
Artists, Art Groups, and concerned citizens at the Supreme Court,
questioning the legality of the so-called “presidential insertion.”
UT WOS:000289823100003
SN 0115-8988

Publication type J
Author/s Vanhoutte, WMA
Vol 40
Issue 2
Start page 192
End page 211
Publication year 2011
Times cited 0
Abstract Contemporary philosophy is said to focus on particular issues, rather
than on comprehensive syntheses. The following contribution intends to
join this trend by offering some reflections on the “animal rights”
debate, which is to be situated within the wider context of
environmental philosophy. While classical Western concepts of man were
anthropocentric, recent cultural developments have triggered a
rediscovery of Nature, especially of nonhuman animals, while focusing
on their affiliations with us, humans. Appropriate relations with those
animals require a respectful attitude on the human side, as if those
animals had full moral and legal rights. But is this not an illusion?
Can we talk about real “rights” for animals, or should we just remain
aware of them having their own feelings and take care not to hurt them,
unless for a “serious” cause? While taking note of the wide variety of
animal species and habitats (a dog is not a fish, while pets are
different from farm animals or animals in the wild), the answer to this
question may have its bearings on one’s personal choices regarding
food, clothing, entertainment, etc.
UT WOS:000289823100005
SN 0115-8988

Publication type J
Title Essentials of logic
Author/s de Vera, DA
Vol 40
Issue 2
Start page 212
End page 216
Publication year 2011
Times cited 0
UT WOS:000289823100006
SN 0115-8988

Publication type J
Title Relationship between asthma control status, the Asthma Control Test
(TM) and urgent health-care utilization in Asia
Author/s Lai, CKW Ko, FWS Bhome, A De Guia, TS Wong, GWK Zainudin, BZ Nang, AN Boonsawat, W Cho, SH Gunasekera, KD Hong, JG Hsu, JY Viet, NN Yunus, F Mukhopadhyay, A
Journal source RESPIROLOGY
Vol 16
Issue 4
Start page 688
End page 697
Publication year 2011
Times cited 0
Abstract Background and objective: Accurate assessment of control is an integral
part of asthma management. We investigated the relationship between
control status derived from the Global Initiative for Asthma (GINA),
the Asthma Control Test (ACT) and urgent health-care utilization.
Methods: Asthma Insights and Reality in Asia-Pacific Phase 2 (AIRIAP 2)
was a cross-sectional, community-based survey of 4805 subjects with
asthma from urban centres across Asia. A symptom control index was
derived from the AIRIAP 2 questionnaire using the GINA control criteria
for day-and night-time symptoms, need for rescue medication, activity
limitation and exacerbations; lung function was excluded. The main
outcomes were asthma control, based on these GINA criteria and the ACT,
and the relationship between control and self-reported urgent
health-care utilization (hospitalization, emergency room visits or
other unscheduled urgent visits) related to asthma over the previous 12
Results: Each of the symptom criteria was significantly associated with
urgent health-care utilization, with odds ratios (ORs) ranging from
2.25 (95% confidence interval (CI): 1.94-2.61) for daytime symptoms to
2.57 (95% CI: 2.29-2.90) for nocturnal awakening. Similarly, control
status was significantly associated with urgent health-care
utilization, with ORs of 0.19 (95% CI: 0.13-0.28), 0.70 (95% CI:
0.65-0.76) and 1.00 for controlled, partly controlled and uncontrolled,
respectively. The optimal ACT cut-off score for identifying
uncontrolled asthma was <= 19 for subjects aged >= 12 years. Urgent
health-care utilization was reported by 57.2% versus 28.7% of patients
scoring <= 19 versus > 19 (P < 0.001).
Conclusions: The GINA control classification and the ACT are valid
symptom-based measures that are significantly associated with urgent
health-care utilization.
UT WOS:000289893700018
SN 1323-7799
doi 10.1111/j.1440-1843.2011.01954.x

Publication type J
Title Could international medical graduates offer a solution to the surgical
workforce crisis? Balancing national interest and global responsibility
Author/s Itani, KMF Hoballah, J Kaafarani, H Crisostomo, AC Michelassi, F
Journal source SURGERY
Vol 149
Issue 5
Start page 597
End page 600
Publication year 2011
Times cited 0
UT WOS:000289930700001
SN 0039-6060
doi 10.1016/j.surg.2010.12.011

Publication type J
Title Prevailing oxic environments in the Pacific Ocean during the
mid-Cretaceous Oceanic Anoxic Event 2
Author/s Takashima, R Nishi, H Yamanaka, T Tomosugi, T Fernando, AG Tanabe, K Moriya, K Kawabe, F Hayashi, K
Vol 2
Publication year 2011
Times cited 0
Abstract The occurrence of Oceanic Anoxic Event 2 (OAE2) 94 million years ago is
considered to be one of the largest carbon cycle perturbations in the
Earth’s history. The marked increase in the spatial extent of the
anoxic conditions in the world’s oceans associated with OAE2 resulted
in the mass accumulation of organic-rich sediments. Although extensive
oceanographic studies of OAE2 have been undertaken in the Atlantic
Ocean, the Tethys Sea, and the epicontinental seas of Europe and
America, little is known about OAE2 in the Pacific Ocean. Here, we
present high-resolution carbon-isotope and degree of pyritization (DOP)
data from marine sequences that formed along the continental margins of
North America and Asia below the northeastern and northwestern Pacific
Ocean. The predominance of low DOP values in these areas revealed that
the continental margins of the Pacific Ocean were oxic for most of the
OAE2 interval.
UT WOS:000289982600024
SN 2041-1723
doi 10.1038/ncomms1233

Publication type J
Title Sympathetic Ophthalmia in an Infected Post-Scleral Buckling Eye
Author/s Sy-Ongkeko, JMB Agahan, ALD Lopez, JS Dy-Liacco, JU
Vol 40
Issue 3
Start page 147
End page 148
Publication year 2011
Times cited 0
UT WOS:000289926900009
SN 0304-4602

Publication type J
Title Pilot-scale commercialization of iron-fortified rice: Effects on anemia
Author/s Angeles-Agdeppa, I Saises, M Capanzana, M Juneja, LR Sakaguchi, N
Vol 32
Issue 1
Start page 3
End page 12
Publication year 2011
Times cited 0
Abstract Background. Rice, the staple food of the Philippines, is an appropriate
vehicle for iron fortification to combat the high prevalence of
iron-deficiency anemia. A previous study among schoolchildren
supplemented with iron-fortified rice showed a significant reduction in
the rate of iron-deficiency anemia from 100% to 33%.
Objective. To document the processes involved in commercializing
iron-fortified rice and to determine its effects on anemia prevalence.
Subjects and methods. This study was conducted on 766 mothers and their
children aged 6 to 9 years in Orion, Bataan. Soliciting political
support, networking with local organizations, market surveys, and
social marketing activities were conducted. The iron content of
iron-fortified rice was tested for each production run. Hemoglobin
measurements were performed on the mothers and children at baseline and
Results. A municipal ordinance to sell iron-fortified rice was issued,
while the local federation provided funds to kick off the sale of
iron-fortified rice. Sales of iron-fortified rice were highest when the
rice was sold at Php 27 (Php 1 = US$0.025) per kilogram and lowest when
the price was Php 37 per kilogram or greater. The municipal ordinance
was not strictly enforced because of the global rice crisis. Social
marketing activities encouraged families to buy iron-fortified rice.
The iron content of the iron-rice premix was within the set
specification limits of 600 to 760 mg of iron per 100 g of premix,
while the iron-fortified rice was within 3 to 3.8 mg of iron and 1 to 2
mg (BC No. 2009-010) per 100 g of raw and cooked fortified rice,
respectively. The decrease in the rate of anemia was significant among
children (from 17.5% to 12.8%) but not among mothers (from 13.0% to
12.5%) after 9 months of study implementation.
Conclusions. Strong political support and intensive social marketing
activities are crucial inputs in commercializing iron-fortified rice.
Keeping the cost affordable and maintaining the commitment of
identified partners were the key factors for providing a continuous
supply of iron-fortified rice. Commercializing iron-fortified rice can
be considered as one of the strategies for decreasing anemia
UT WOS:000290137700001
SN 0379-5721

Publication type J
Title Tannin-rich fraction from Terminalia catappa inhibits quorum sensing
(QS) in Chromobacterium violaceum and the QS-controlled biofilm
maturation and LasA staphylolytic activity in Pseudomonas aeruginosa
Author/s Taganna, JC Quanico, JP Perono, RMG Amor, EC Rivera, WL
Vol 134
Issue 3
Start page 865
End page 871
Publication year 2011
Times cited 0
Abstract Aim of the study: The study aimed to test the activity of Terminalia
catappa L against bacterial quorum sensing (QS) in order to provide a
potential scientific basis for the traditional use of leaf extracts of
this plant as an antiseptic.
Materials and methods: The anti-QS activity of the methanolic leaf
extract of Terminalia catappa was detected through the inhibition of
the QS-controlled violacein pigment production in Chromobacterium
violaceum. Fractions resulting from size-exclusion chromatography were
assayed. The most active fraction was characterized through qualitative
phytochemical detection methods. The effect of this fraction on known
QS-controlled phenotypes in test strains was assessed.
Results: The fraction with the highest activity (labeled as TCF12) was
characterized to be tannin-rich. It specifically inhibited
QS-controlled violacein production in Chromobacterium violaceum with
50% reduction achieved at 62.5 mu g mL(-1) without significantly
affecting growth up to about 962 mu g mL(-1). The assessment of its
effects on LasA activity of Pseudomonas aeruginosa ATCC 10145 found
that the production of this virulence determinant is reduced in a
concentration dependent manner with about 50% reduction at 62.5 mu g
mL(-1). Furthermore, it was found that TCF12 was able to inhibit the
maturation of biofilms of Pseudomonas aeruginosa, a phenotype that has
also been known to be QS-regulated.
Conclusion: Therefore, tannin-rich components of Terminalia catappa
leaves are able to inhibit certain phenotypic expression of QS in the
test strains used. (C) 2011 Elsevier Ireland Ltd. All rights reserved.
UT WOS:000289866500035
SN 0378-8741
doi 10.1016/j.jep.2011.01.028

Publication type J
Title Interrater Reliability of the Pediatric National Institutes of Health
Stroke Scale (PedNIHSS) in a Multicenter Study
Author/s Ichord, RN Bastian, R Abraham, L Askalan, R Benedict, S Bernard, TJ Beslow, L deVeber, G Dowling, M Friedman, N Fullerton, H Jordan, L Kan, L Kirton, A Amlie-Lefond, C Licht, D Lo, WR McClure, C Pavlakis, S Smith, SE Tan, M Kasner, S Jawad, AF
Journal source STROKE
Vol 42
Issue 3
Start page 613
End page 617
Publication year 2011
Times cited 1
Abstract Background and Purpose-Stroke is an important cause of death and
disability among children. Clinical trials for childhood stroke require
a valid and reliable acute clinical stroke scale. We evaluated
interrater reliability (IRR) of a pediatric adaptation of the National
Institutes of Health Stroke Scale.
Methods-The pediatric adaptation of the National Institutes of Health
Stroke Scale was developed by pediatric and adult stroke experts by
modifying each item of the adult National Institutes of Health Stroke
Scale for children, retaining all examination items and scoring ranges
of the National Institutes of Health Stroke Scale. Children 2 to 18
years of age with acute arterial ischemic stroke were enrolled in a
prospective cohort study from 15 North American sites from January 2007
to October 2009. Examiners were child neurologists certified in the
adult National Institutes of Health Stroke Scale. Each subject was
examined daily for 7 days or until discharge. A subset of patients at 3
sites was scored simultaneously and independently by 2 study
Results-IRR testing was performed in 25 of 113 a median of 3 days
(interquartile range, 2 to 4 days) after symptom onset. Patient
demographics, total initial pediatric adaptation of the National
Institutes of Health Stroke Scale scores, risk factors, and infarct
characteristics in the IRR subset were similar to the non-IRR subset.
The 2 raters’ total scores were identical in 60% and within 1 point in
84%. IRR was excellent as measured by concordance correlation
coefficient of 0.97 (95% CI, 0.94 to 0.99); intraclass correlation
coefficient of 0.99 (95% CI, 0.97 to 0.99); precision measured by
Pearson rho of 0.97; and accuracy measured by the bias correction
factor of 1.0.
Conclusions-There was excellent IRR of the pediatric adaptation of the
National Institutes of Health Stroke Scale in a multicenter prospective
cohort performed by trained child neurologists. (Stroke. 2011; 42:
UT WOS:000287479401448
SN 0039-2499
doi 10.1161/STROKEAHA.110.607192

Publication type J
Title The epidemiology of osteoarthritis in Asia
Author/s Fransen, M Bridgett, L March, L Hoy, D Penserga, E Brooks, P
Vol 14
Issue 2
Start page 113
End page 121
Publication year 2011
Times cited 1
Abstract Worldwide, osteoarthritis (OA) is estimated to be the fourth leading
cause of disability. Most of this disability burden is attributable to
the involvement of the hips or the knees. OA is strongly associated
with ageing and the Asian region is ageing rapidly. Further, OA has
been associated with heavy physical occupational activity, a required
livelihood for many people living in rural communities in developing
countries. Unfortunately, joint replacement surgery, an effective
intervention for people with severe OA involving the hips or knees, is
inaccessible to most people in these regions. On the other hand,
obesity, another major risk factor, may be less prevalent, although it
is on the increase. Determining region-specific OA prevalence and risk
factor profiles will provide important information for planning future
cost-effective preventive strategies and health care services. An
update of what is currently known about the prevalence of hip and knee
OA from population-based studies conducted in the Asian region is
presented in this review. Many of the recent studies have conducted
comparisons between urban and rural areas and poor and affluent
communities. The results of Asian-based studies evaluating risk factors
from population-based cohorts or case-control studies, and the current
evidence on OA morbidity burden in Asia is also outlined.
UT WOS:000289901600002
SN 1756-1841
doi 10.1111/j.1756-185X.2011.01608.x

Publication type J
Title What about supplements for osteoarthritis? A critical and
evidenced-based review
Author/s Vista, ES Lau, CS
Vol 14
Issue 2
Start page 152
End page 158
Publication year 2011
Times cited 0
Abstract Dietary supplements have inundated the commercial market in recent
times. These so called “health” supplements are being marketed as
beneficial in the prevention and regression of several common medical
conditions that include osteoarthritis. This review provides an
overview of osteoarthritis as a common disease and elucidates the
disease process in relation to conventional therapeutic approaches. We
also attempt to present perspectives about the dietary industry,
focusing on the widely available dietary supplements for
osteoarthritis; then we discuss the current available evidence
regarding these common dietary supplements which are finally
consolidated and enumerated as major key points.
UT WOS:000289901600007
SN 1756-1841
doi 10.1111/j.1756-185X.2011.01619.x

Publication type J
Title Physiological and Proteomic Responses of Rice Peduncles to Drought
Author/s Muthurajan, R Shobbar, ZS Jagadish, SVK Bruskiewich, R Ismail, A Leung, H Bennett, J
Vol 48
Issue 2
Start page 173
End page 182
Publication year 2011
Times cited 0
Abstract Panicle exsertion, an essential physiological process for obtaining
high grain yield in rice is mainly driven by peduncle (uppermost
internode) elongation. Drought at heading/panicle emergence prevented
peduncle elongation from reaching its maximum length even after
re-watering. This inhibitory effect of drought resulted in delayed
heading and trapping spikelets lower down the panicle inside the
flag-leaf sheath, thus increasing sterility in the lower un-exserted
spikelets and also among the upper superior spikelets whose exsertion
was delayed. Intermittent drought stress caused a significant reduction
in relative water content (RWC) and an increase in the abscisic acid
(ABA) level of the peduncles, while both returned to normal levels upon
re-watering. Semi-quantitative reverse transcription polymerase chain
reaction (RT-PCR) analysis revealed the down-regulation of GA
biosynthetic genes during drought. 2D-PAGE analysis of proteins from
peduncles collected under well-watered, drought-stressed, and
re-watered plants revealed at least twofold differential changes in
expression of 31 proteins in response to drought and most of these
changes were largely reversed by re-watering. The results indicate that
ABA-GA antagonism is a key focal point for understanding the failure of
panicle exsertion under drought stress and the consequent increase in
spikelet sterility.
UT WOS:000289800000009
SN 1073-6085
doi 10.1007/s12033-010-9358-2

Publication type J
Title Glare in a Case of a Craniopharyngioma
Author/s Reyes, KB Goh, KY Cullen, JF
Vol 35
Issue 2
Start page 73
End page 75
Publication year 2011
Times cited 0
Abstract Glare is commonly encountered in patients with corneal disease,
uveitis, or retinal problems. Rarely, it may be a presenting
manifestation of more sinister conditions such as chiasmal lesions. We
present the case of a 42-year-old male who complained of glare for 2-3
months. There was neither headache nor blurring of vision. His
neuro-ophthalmological examination was within normal limits except for
slight decrease in colour contrast of the upper temporal dots of the
red-dot perimetry chart. Automated visual fields showed a central
scotoma on the right eye and a temporal-inferior field defect on the
left. He underwent neuro-imaging, which revealed a suprasellar cystic
mass, most likely a craniopharyngioma. Referral to the neurosurgeon was
made who performed supraorbital keyhole surgery. Intraoperative
findings showed a cystic mass stuck bilaterally on the optic nerves,
carotids, and optic chiasm with the pituitary stalk deviated to the
right side. Histopathology report revealed a craniopharyngioma,
adamantinomatous variant. One month post excision, the patient showed
improvement in his visual functions.
UT WOS:000290024600003
SN 0165-8107
doi 10.3109/01658107.2011.557761

Publication type J
Title Southeast Asia in the Global Economy: Securing Competitiveness and
Social Protection
Author/s Park, D
Vol 56
Issue 1
Start page 145
End page 147
Publication year 2011
Times cited 0
UT WOS:000289949400009
SN 0217-5908
doi 10.1142/S0217590811004134

Publication type J
Title Inter-observer Reliability of the Pediatric NIH Stroke Scale (PedNIHSS)
in a Multicenter Study
Author/s Ichord, RN Bastian, R Abraham, L Askalan, R Benedict, S Bernard, T Beslow, L deVeber, G Dowling, M Friedman, N Fullerton, H Jordan, L Kan, L Kirton, A Amlie-Lefond, C  Licht, D Lo, W McClure, C Pavlakis, S Smith, SE Tan, M Jawad, AF
CT International Stroke Conference
CY FEB 08-10, 2011
CL Los Angeles, CA
Journal source STROKE
Vol 42
Issue 3
Start page E98
End page E98
Publication year 2011
Times cited 0
UT WOS:000287479400197
SN 0039-2499